CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
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2025
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IF 1.3
Danping Tian,Ruipeng Hao,Yanzi Zhang,Wanyu Xie,Pei Zhang,Wenbo Lu
A novel electrochemical sensing platform was developed based on copper-based metal-organic framework (Cu-MOF) microcapsules synthesized via a Pickering emulsion templating approach, where carbon nanoparticles used as solid emulsifiers to enhance electrode interfacial interactions and material conductivity. This design synergistically combines the superior catalytic activity of Cu-MOF with the conductive carbon matrix. The Cu-MOF microcapsules were applied in the modification of a glassy carbon electrode to obtain an electrochemical sensor for simultaneous detection of dopamine and paracetamol. This sensor showed the good sensing performance with a broad linearity range (2–1600 μM for dopamine and 2–6500 μM for paracetamol) and low detection limits (1.69 μM for dopamine and 1.81 μM for paracetamol at S/N = 3). This platform also demonstrated excellent reproducibility (RSD < 3%) and selectivity against common interferents, highlighting its potential for practical applications in real sample detection.
研究领域:
电化学
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材料科学
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分析化学
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纳米技术
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Bing Chang,Fengtao Zhang,Zhaojun Min,Nan Wang,Qingchun Xia,Jing Fan,Maohong Fan,Jianji Wang
Cu-based catalysts, especially co-sites of Cu 0 and Cu Ⅰ , are the best competitors for electrochemical CO 2 fixation to produce multi-carbon (C2 + ) products. However, it is challenging to construct highly stable Cu Ⅰ sites due to the changeability of its valence state and electronic structure in the electroreduction process, and the mechanism is also elusive. Herein, a 2D conductive Cu Ⅱ -MOF film (Cu Ⅱ HHTP@Cu 0 ) is prepared on Cu (1 0 0) foil by in-situ electrochemical assembly. After pre-reduction, the in-situ produced Cu 2 O clusters are confined in the cavities of the film created by the local breaking of the MOF framework to construct a unique Cu Ⅰ -Cu Ⅱ HHTP@Cu 0 catalyst, so that a novel strategy is proposed to stablize highly dispersed Cu Ⅰ sites during electrochemical reduction, thus protecting the Cu 2 O clusters from further reduction and ensuring the coexistence of Cu Ⅰ (1 1 1)-Cu 0 (1 0 0) sites. As such, the current density of CO 2 electrochemical reduction catalyzed by this catalyst exceeds 300 mA cm −2 , the duration overs 50 h, and the C2 selectivity achieves 72.6 %. In-situ spectroscopy and theoretical calculations reveal that the optimized microenvironment of the Cu Ⅰ (1 1 1) sites reduces the energy barrier of *OCCOH coupling, and Cu 0 (1 0 0) sites increase the coverage of *CO, thus boosting the production of C2 products.
研究领域:
材料科学
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电化学
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高影响因子
ACS Applied Nano Materials
·
2024
·
IF 5.3
Chaofan Ma,Qun Yang,Huiyu Su,Huimin Yang,Xiaoxia Wang,Dawen Zeng
P-type semiconductors [copper oxide (CuO) and cuprous oxide (Cu2O)] have been widely researched as good gas sensing materials due to their unique oxygen adsorption properties. In this work, C-doped CuO/Cu2O hollow nano-octahedrons have been prepared by thermal decomposition of the Cu-based metal–organic framework ([Cu3(BTC)2]n). The CuO and Cu2O nanoparticles form nano-octahedron heterojunctions by a close packing mode. A large number of active heterojunction sites were exposed, which significantly increased the adsorbed oxygen (O2–) content. Meanwhile, doping C in the lattice of the heterojunction effectively reduces the band gap of CuO/Cu2O and promotes the chemical reaction of the target gas on the surface of the material. Density functional theory calculations indicate that the CuO/Cu2O heterojunction has strong adsorption ability for NO2. Electrochemical impedance spectroscopy further reveals that C-doped CuO/Cu2O hollow nano-octahedrons-40 min heterojunction has the best electron transport performance. The sensors have good gas sensing response (22.88–50 ppm) and selectivity to nitrogen dioxide (NO2) at room temperature (28 °C). In addition, the sensor has extremely low detection, which can detect parts per billion level NO2 (20.50% to 100 ppb). It is expected to provide a reference for the development of a room-temperature NO2 sensor.
研究领域:
材料科学
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化学
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环境科学
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高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 3
·168
·
IF 5.4
Ma Ya,Zheng Yuqing,Wang Jiahao,Bai Liwei,Liu Jizhong,Bai Weidong,Zhao Xiaojuan
Cu-metal organic framework (MOF) derived porous carbon (Cu/Cu 2 O@C 700 ) derived from Cu-based MOF was prepared by one-step pyrolysis, and then used together with nitrogen-doped longan shell carbon (NCs) to establish a new electrochemical sensor for the rapid detection of enrofloxacin (ENR) by differential pulse voltammetry. The materials and the preparation process of electrochemical sensor were characterized. Results have shown that Cu/Cu 2 O@C 700 exhibited abundant porous structures, high surface area, and numerous active sites, which significantly improved response sensitivity. NCs is a porous carbon material which possess high specific surface area and make the diffusion and transport of electrolyte ions easier. Under optimal conditions, the peak current of ENR exhibits favorable linear relationships with the concentration within a range 0.1–1000 ng mL − 1 , and the detection limit is 7.73 × 10 − 3 ng mL −1 (S/ N = 3). The sensor has good selectivity, stability and repeatability, and good recovery (93.90 ~ 104.0%, RSD<4%) for the detection of ENR in fresh fish and shrimp. Compared with LC-MS/MS, it also shows competitive accuracy, which is of great significance in ensuring the safety of aquatic products. Graphical abstract
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高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
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2024
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IF 4
Kai Zhang,Dan Hou,Dongping Wu,Yanxia Li,Xuemei He,Tingting Sun,Jianhua Xiong,Xiaoning Liao
Accurate detection of benzimidazole pesticide thiophanate-methyl (TM) is of vital importance due to its harm to environmental safety and human health. Herein, for the first time, we developed a sensitive nonenzymatic electrochemical sensor for TM detection based on multiwall carbon nanotubes (MWCNTs) functionalized bimetallic iron−copper organic frameworks (Fe/Cu MOF). The synthesized nanocomposites showed excellent electro-oxidation ability to TM owing to the synergistic effect between MWCNTs and Fe/Cu MOF. Fe/Cu MOF enhanced the specific surface area for MWCNTs and MWCNTs improved the conductivity for Fe/Cu MOF, which resulted in a nanocomposite with abundant catalytical active sites and superior conductivity, greatly amplifying the detection signal for TM. Under optimized conditions, the proposed sensor based on the composite presented a wide linearity from 0.3 nM to 200 nM which is wider than that of currently reported methods and a very low detection limit (LOD) of 0.1 nM far lower than the maximum residue levels (MRLs) enacted worldwide. Furthermore, the sensor showed good reproducibility, long-term stability and high anti-interference. Moreover, the sensor can be successfully employed for the determination of TM in apple and cucumber with good recoveries (80.96 %–105. 5 %), highlighting its excellent potential as an alternative to traditional techniques.
研究领域:
环境科学
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分析化学
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高影响因子
Biomaterials Science
·
2022
·Vol. 11
·期 1
·322-338
·
IF 7.59
Jianwen Zhang,Xianlan Ke,Maotao Huang,Xinyu Pei,Shuai Gao,Dimeng Wu,Junying Chen,Yajun Weng
The anticoagulation and antibacterial functions of implant and interventional catheters during indwelling will determine their success or failure. Here, an amino-containing copper-based metal–organic framework (Cu-MOF) coating was prepared on the thermoplastic polyurethane substrate (TPU) surface by spin coating for anti-thrombotic and anti-infection effects. The adhesion properties of the polyurethane prepolymer coating (PC) enhanced the binding force of Cu-MOF particles and TPU surface and improved stability. Due to the coordination affinity of Cu2+ with nitric oxide (NO) and the NO loading capacity of the amino group, it showed that a large amount of NO was loaded in the coating. Meanwhile, the coordinated Cu2+ in the coating also catalyzed endogenous NO donors to generate NO, which prolonged the NO release for up to 30 days. The results of antibacterial experiments showed that the NO released from the coating had good antibacterial effects on both E. coli and S. epidermidis. An obvious antibacterial ring can be seen and the antibacterial rate was higher than 96%. It also showed inhibiting platelet adhesion and activation, prolonged in vitro clotting time and inhibited thrombus formation. In summary, for the first time, NO release from the coating was realized by the combined ways of NO donor and catalytic endogenous NO donor. It can not only meet the high NO release rate required for early anticoagulation and antibacterial of the catheter but also maintain normal anticoagulation requirements in the later period.
研究领域:
材料科学
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生物材料
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生物医学工程
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PubMed
高影响因子
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
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2022
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IF 4.831
Ningning Zhang,Lixin Zhao,Mengting He,Peng Luo,Liang Tan
A highly sensitive and selective sensor for the quantitative assay of inorganic pyrophosphatase (PPase) activity was developed based on a fluorescence “turn–off” strategy. Carbon quantum dots@Cu(II)-based metal–organic framework nanotubes (CQDs@Cu-MOF) with length less than 300 nm and width less than 20 nm were synthesized. CQDs in the nanotubes exhibited weak fluorescence owing to static quenching. The coordination reaction between pyrophosphate ion (PPi) and Cu(II) decomposed CQDs@Cu-MOF and led to the release of CQDs, of which the fluorescence recovered. In the presence of PPase, the hydrolysis of PPi generated phosphate ion (Pi). CQDs@Cu-MOF remained their structural stability and the fluorescence turned off. The fluorescence intensity difference of the mixture of CQDs@Cu-MOF and PPi in the absence and presence of PPase (-Δ F ) was proportional to the PPase concentration from 0.1 to 5 mU mL −1 and that from 5 to 50 mU mL −1 , and a limit of detection at 0.03 mU mL −1 was obtained. PPase activity in human serum was analyzed using the proposed fluorescence sensor and the recovery values were found to vary from 95.0% to 104 %.
研究领域:
生物化学
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分析化学
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PubMed
高影响因子
ACS Omega
·
2025
·
IF 4.3
Dongpeng Sun,Shumei Kang,Jinghao Li,Hong Chen,Xintong Li,Hongyan Qi
Copper-based metal–organic frameworks (Cu-MOFs) show great promise in corrosion protection due to their large specific surface area and inherent antibacterial properties. However, when applied to epoxy resin (EP) coatings, their tendency to agglomerate and the instability of the passive films formed during corrosion compromise the anticorrosion performance of the composite materials. To overcome these challenges, this study synthesized a series of zinc–copper bimetallic MOFs (Zn/Cu-MOFs) by incorporating zinc ions with similar ionic radii during the synthesis process. The surface morphology and ion release characteristics of the Zn/Cu-MOFs were comprehensively characterized using FE-SEM, XRD, FTIR, XPS, and ICP-OES. Subsequently, taking Zn10/Cu-MOF (fabricated with a Zn2+-to-Cu2+ volume ratio of 1:9) as an example, the anticorrosion performance of the nanoparticles was assessed in both solution and coating systems. Remarkably, Zn10/Cu-MOF nanoparticles achieved a corrosion inhibition efficiency of 89.7% for carbon steel after 24 h of immersion. Furthermore, electrochemical impedance spectroscopy (EIS) and salt spray tests on the coatings demonstrated that Zn10/Cu-MOFs impart efficient corrosion resistance and self-healing ability to the EP matrix. After 40 days of immersion in 3.5 wt % NaCl solution, the Zn10/Cu-MOF@EP coating exhibited a significantly higher low-frequency impedance modulus (|Z|0.01 Hz ≈ 108 Ω·cm2) compared to Cu-MOF@EP (∼106 Ω·cm2) and pure EP (∼105 Ω·cm2).
研究领域:
材料科学
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腐蚀工程
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纳米材料
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涂层技术
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金属有机框架（MOFs）
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DOI
PubMed
高影响因子
COMPOSITES PART A-APPLIED SCIENCE AND MANUFACTURING
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2025
·
IF 8.9
Xiang Li,Wenjie Zhao,Guosong Wu,Yinghao Wu
The harsh service environment in the splash zone poses serious challenges for the long-term durability of steel pipe piles. The basalt fibers (BF) reinforced-composite coatings have acquired great attention in various fields such as offshore wind power equipment and construction industry due to the high strength and chemical stability. However, the service life of BF reinforced-composite coatings is greatly restricted by poor interfacial compatibility between BFs and polymer resin. In this work, we fabricated a BF reinforced epoxy powder composite coating with excellent erosion resistance by constructing L-Cys@Cu MOF on BFs. The interfacial shear strength value between MBF and EP was 49.66 % larger than that of BF. Contrasted to EP, the adhesion strength between 2.5 %MBF/EP coating and the steel substrate was 79.65 MPa, which was increased by 24.67 %. Interestingly, the mass and volume loss of 2.5 %MBF/EP coating was decreased by 22.77 % and 21.16 %, respectively, compared with 2.5 %CBF/EP coating. These results demonstrate the broader applicability of BF in composite materials, arising from the synergistic effect of mechanical interlocking between MBF and EP and the formation of cross-linking network between L-Cys@Cu MOF and EP. This work provides a novel perspective for the development of BF reinforced-composite coatings with long-term erosion resistance.
研究领域:
材料科学
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腐蚀工程
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复合材料
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表面改性
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海洋防护涂层
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DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
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2026
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IF 6.7
Yanfang Zhu,Dongdong Kang,Zhiyuan Huang,Guiyang Xu
Photocatalytic H 2 production and pollutant degradation using solar-driven processes are promising approaches for sustainable energy conversion. However, the reaction efficiency is inadequate due to rapid carrier (e -/ h + ) recombination and poor catalyst stability. In this work, we report a novel heterostructure comprising iridium-modified Cu-MOF coupled with sulfur-doped HfO 2 (S-HfO 2 ), termed as Ir-Cu-MOF/S-HfO 2 composite, to investigate photocatalytic H 2 production and bisphenol-A (BPA) degradation. Advanced characterization studies, such as X-ray diffraction (XRD), scanning and transmission electron microscopy (SEM & TEM), X-ray photoelectron spectroscopy (XPS), electrochemical impedance spectroscopy (EIS), and electron spin resonance (ESR), were used to explicate the structural, morphological, electronic, and charge transfer performances of the Ir-Cu-MOF/S-HfO 2 composite. Under LED-light irradiation, the Ir-Cu-MOF/S-HfO 2 photocatalyst displays a H 2 evolution rate of 12.98 mmol g -1 h -1 using triethanolamine (TEOA) as a sacrificial agent. Simultaneously, it achieves 96% degradation of bisphenol-A (BPA) within 120 min, with a rate constant of 0.018 min -1 , representing superior bifunctional photocatalytic activities. Characteristics studies suggest that the synergistic interaction between Ir-infused Cu-MOF active centres and defect-rich S-HfO 2 facilitates the efficient separation and migration of photogenerated charge carriers. Moreover, the Ir-Cu-MOF/S-HfO 2 photocatalyst exhibits good stability and reusability over prolonged cycles. This study provides valuable insights into the clear design of noble metal-modified MOF-based heterostructures and highlights their potential for integrated solar-driven hydrogen production and environmental pollutant abatement.
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高影响因子
Chemosensors
·
2025
·Vol. 13
·期 6
·200
·
IF 3.7
Xuanlin Feng,Jiaqi Zhao,Shiwei Wu,Ying Kan,Honemei Li,Weifei Zhang
Hydroxychloroquine (HCQ), a cornerstone therapeutic agent for autoimmune diseases, requires precise serum concentration monitoring due to its narrow therapeutic window. Current HCQ monitoring methods such as HPLC and LC-MS/MS are sensitive but costly and complex. While electrochemical sensors offer rapid, cost-effective detection, their large chambers and high sample consumption hinder point-of-care use. To address these challenges, we developed a microfluidic electrochemical sensing platform based on a screen-printed carbon electrode (SPCE) modified with a hierarchical nanocomposite of gold nanoparticles (AuNPs), copper-based metal–organic frameworks (Cu-MOFs), and multi-walled carbon nanotubes (MWCNTs). The Cu-MOF provided high porosity and analyte enrichment, MWCNTs established a 3D conductive network to enhance electron transfer, and AuNPs further optimized catalytic activity through localized plasmonic effects. Structural characterization (SEM, XRD, FT-IR) confirmed the successful integration of these components via π-π stacking and metal–carboxylate coordination. Electrochemical analyses (CV, EIS, DPV) revealed exceptional performance, with a wide linear range (0.05–50 μM), a low detection limit (19 nM, S/N = 3), and a rapid response time (<5 min). The sensor exhibited outstanding selectivity against common interferents, high reproducibility (RSD = 3.15%), and long-term stability (98% signal retention after 15 days). By integrating the nanocomposite-modified SPCE into a microfluidic chip, we achieved accurate HCQ detection in 50 μL of serum, with recovery rates of 95.0–103.0%, meeting FDA validation criteria. This portable platform combines the synergistic advantages of nanomaterials with microfluidic miniaturization, offering a robust and practical tool for real-time therapeutic drug monitoring in clinical settings.
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高影响因子
Biomaterials Advances
·
2025
·
IF 6
Gao Pan,Qi Zhong,Tiange Wang,Xiuwen Gao,Huixing Li,Jiajun Li,Hui Yang,Cijun Shuai,Shuping Peng
Molybdenum disulfide (MoS 2 ), a typical piezoelectric sonosensitive material, holds great promise in ultrasound-activated catalytic antibacterial applications and osteogenic differentiation promotion. However, it has two key limitations: rapid carrier recombination leading to insufficient antibacterial activity; and difficulty in forming stable interfaces with biopolymers as an inorganic compound, which impairs effective sonocurrent transmission in heterojunction scaffolds for osteogenesis induction. To address these issues, we proposed a multi-beneficial strategy: anchoring Cu-MOF to MoS 2 via Cu S chemical bonds to construct a Type-II MoS 2 /Cu-MOF heterojunction. Under ultrasonic stimulation, this heterojunction undergoes polarization to form a built-in electric field, accelerating carrier separation and enhancing catalytic efficiency. Additionally, Cu-MOF releases Cu + and Cu 2+ ions, which undergo Fenton-like reactions with bacterial endogenous H 2 O 2 and glutathione to generate hydroxyl radicals via chemodynamic effects, increasing reactive oxygen species (ROS) production; the resultant oxygen further boosts sonodynamic efficiency. Furthermore, Cu 2+ in MoS 2 /Cu-MOF forms metal coordination bonds with carboxyl groups in poly-l-lactic acid (PLLA) macromolecules, constructing an interfacial “Line-Point-Plane” ternary structure that enhances interfacial electron transfer efficiency, facilitates sonocurrent transmission, and thus effectively realizes electrical stimulation for osteogenic differentiation. Specifically, we incorporated the heterojunction into PLLA matrix powder and fabricated MoS 2 /Cu-MOF/PLLA heterojunction scaffolds via selective laser sintering (SLS). Under ultrasonic stimulation, these scaffolds achieve synergistic sono/chemodynamic antibacterial activity, while ultrasound-activated sonocurrents transmit through the ternary interfacial structure of the heterojunction scaffolds to effectively induce osteogenic differentiation. Results showed that compared to pure MoS 2 scaffolds, the heterojunction scaffold exhibited a 0.4 eV narrower band gap and a 350 Ω lower impedance, with antibacterial rates of 97.3 % and 98 % against Staphylococcus ( S.aureus ) and Escherichia coli ( E.coli ), respectively. Notably, under ultrasonic irradiation, the upregulation of osteogenic factors such as Wnt-10b is induced, and osteoblast differentiation is promoted simultaneously; the results indicate that osteogenic factors like Wnt-10b have a potential role in promoting osteoblast differentiation under ultrasonic conditions.
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高影响因子
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