ACS Applied Materials & Interfaces
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2022
·
IF 10.383
Ge Xie,Shuo Du,Qiuyi Huang,Min Mo,Yujie Gao,Miaomiao Li,Juan Tao,Lianbin Zhang,Jintao Zhu
Rapid and sensitive diagnostics in the early stage of bacterial infection and immediate treatment play critical roles in the control of infectious diseases. However, it remains challenging to develop integrated systems with both rapid detection of bacterial infection and timely on-demand disinfection ability. Herein, we demonstrate a photonic hydrogel platform integrating visual diagnosis and on-site photothermal disinfection by incorporating Fe3O4@C nanoparticles into a poly(hydroxyethyl methacrylate)-co-polyacrylamide (PHEMA-co-PAAm) matrix. In vitro experiments demonstrate that such a hydrogel can respond to pH variation caused by bacterial metabolism and generate the corresponding color changes to realize naked-eye observation. Meanwhile, its excellent photothermal conversion ability enables it to effectively kill bacteria by destroying cell membranes under near-infrared irradiation. Moreover, the pigskin infection wound model also verifies the bacterial detection performance and disinfection ability of the hydrogel in vivo. Our strategy demonstrates a new approach for visual diagnosis and treatment of bacterial infections.
研究领域:
生物医学工程
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材料科学
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传染病学
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纳米技术
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DOI
PubMed
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Pei Su,Xuedong Du,Yang Zheng,Wenyang Fu,Qizhan Zhang,Minghua Zhou
A bifunctional catalyst with Ce-based metal–organic frameworks deposited on carbon encapsulated Fe 3 O 4 particles (Ce-MOFs/Fe 3 O 4 @C) was prepared for heterogeneous electro-Fenton (EF), which exhibited high H 2 O 2 generation efficiency (over 90% selectivity and 80.7% current efficiency), high sulfamethazine (SMT) removal with very low electric energy consumption (7.65 kWh kg −1 SMT), and wider pH suitability to alkaline environment (pH 9). The highest content of oxygen vacancies (O V ), Ce 3+ and Fe 2+ was simultaneously exhibited when the Fe/Ce ratio in precursor was 2:1. Interface-confined between Ce-MOFs and Fe 3 O 4 @C and presence of O V promoted the O 2 adsorption for oxygen reduction reaction and O 2 ∙- generation, and electron transfer between Fe and Ce. Meanwhile, the presence of Fe 2+ /Fe 3+ and Ce 3+ /Ce 4+ simultaneously facilitated the sequential catalysis induced by H 2 O 2 to generate ∙ OH, and Ce 4+ could promote O 2 ∙- to generate 1 O 2 . This work provides new insight into the design and synthesis of Fe-based catalysts in EF with interface confinement and multi-layered reaction centers to improve the generation and the decomposition of H 2 O 2 at the same time at a low cathode potential.
研究领域:
环境科学
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催化化学
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DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
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2019
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IF 9.518
Rui Zhang,Na Lu,Jiaxing Zhang,Ruohong Yan,Jie Li,Lihua Wang,Na Wang,Min Lv,Min Zhang
In enzyme-based immunoassys, the use of natural enzyme has been remarkably restricted by the inconvenience in preparation and storage, especially for point-of-care testing. Nanozymes, which can mimic the functions of natural enzymes, have been regarded as promising alternatives due to their robust stability and convenience in fabrication. Here we fabricated one-dimensional Fe 3 O 4 @C core-shell nanostructures via a solvent-thermal method. Thus prepared nanocomposites showed excellent peroxidase-like activity, capable of catalyzing chromogenic substrates into colored products in the presence of H 2 O 2 . We then developed a nanozyme-linked aptamer sorbent assay (NLASA) in a sandwich format, in which the as-prepared Fe 3 O 4 @C nanowires were employed as catalytic labels for colorimetric detection by naked eyes. In the detection of platelet-derived growth factor BB (PDGF-BB), this assay reliably exhibited detection limits as low as 10 fM, with a working range from 10 fM to 100 nM. By incorporating G-quadruplex-hemin DNAzyme with Fe 3 O 4 @C nanowires, the detection limit could be further lowered to 50 aM. The detection limit of PDGF-BB in 50% human serum was 100 fM. This ultrasensitive, cost-effective and easy-to-operate sensing platform offers new opportunities for protein detection in clinical diagnosis.
研究领域:
生物化学
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纳米技术
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分析化学
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临床诊断
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DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2026
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IF 5.4
Qing Jin,Kai Ma,Guilong Gao,Xinyu Zhou,Lijie Xu,Ying Zhang,Jiangtao Shi,Lu Gan
In this study, a series of carbon nanofiber (CNF) based one-dimensional catalysts were prepared by pyrolyzing MIL-88B(Fe) anchored PAN/lignin electrospun nanofibers, which were then employed to activate peroxymonosulfate (PMS) for bisphenol A (BPA) degradation. The results indicated that adjusting the lignin content in nanofiber precursor could engineer the crystalline phase of iron compounds in the catalysts, as well as their catalytic activity and stability. Specifically, the precursor with lower lignin content was converted into Fe 3 O 4 loaded CNF (P2L1-Fe-C), whereas Fe 3 C loaded CNF was obtained (P1L1-Fe-C) by increasing lignin content to 50 wt% in the nanofiber precursor. Having multiple Fe valence states within Fe 3 C which facilitated internal electron transfer, P1L1-Fe-C exhibited high catalytic activity with high stability and low iron ion leaching when activating PMS for BPA degradation. P1L1-Fe-C/PMS system could produce more kinds of active species including hydroxyl radical (•OH) and multiple non-radical species like singlet oxygen ( 1 O 2 ), high-valent iron-oxo species, and electron transfer process. Comparatively, P2L1-Fe-C/PMS system was only able to produce •OH and 1 O 2 . The existence of more BPA degradation pathways resulted in enhanced resistance of P1L1-Fe-C/PMS system towards various environmental interferences. This study inspires a new thinking of developing iron based Fenton-like catalyst with tunable crystalline phases through precursor recipe regulation, achieving both high activity and stability. Download: Download high-res image (225KB) Download: Download full-size image
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产品关联
DOI
高影响因子
Journal of Materials Chemistry A
·
2018
·Vol. 6
·期 35
·17057-17066
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IF 9.931
Ruiying Shi,Cuiping Han,Hongfei Li,Lei Xu,Tengfei Zhang,Junqin Li,Zhiqun Lin,Ching-Ping Wong,Feiyu Kang,Baohua Li
Li ion capacitors (LICs) are emerging as a promising device to integrate the high power density of supercapacitors with the high energy density of Li ion batteries. However, the insufficient specific capacity of the conventional capacitive electrode presents a great challenge in achieving high energy density for LICs. Herein, we demonstrate the synthesis of hierarchical porous carbon with an extremely large specific surface area of 3898 m2 g−1 and an improved graphitization degree by using egg white biomass as a precursor and NaCl as a template, in which dual functional NaCl served both as a macropore creating template and a graphitic catalyst to enhance the graphitization degree. With rational design, the developed porous carbon exhibits a noticeably enhanced specific capacity of 118.8 mA h g−1 at 0.1 A g−1 with excellent rate capability and improved cycling stability over 4000 cycles in an organic Li ion conducting electrolyte. Furthermore, the obtained porous carbon was employed as a cathode paired with a Fe3O4@C anode for LIC applications, which delivers an integrated high energy density of 124.7 W h kg−1 and a power density of 16 984 W kg−1 as well as a superior capacity retention of 88.3% after 2000 cycles at 5 A g−1, demonstrating the promising application as potential electrode candidates for efficient energy storage systems.
研究领域:
材料科学
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电化学
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能源存储
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DOI
高影响因子
危险品化学品经营许可证（带存储）