ADVANCED FUNCTIONAL MATERIALS
·
2025
·
IF 19
Wei Yu,Xinru Zhang,Muge Gu,Yihui Zhang,Xiangqi Zhang,Jiayu Wang,Genjiang Zheng,Wei-En Yuan
Peripheral nerve injuries, often caused by trauma and tumor resection, severely impair motor and sensory functions. While autologous nerve grafting remains the gold standard, its efficiency is hindered by limited donor tissue availability, donor site morbidity, and neuropathic pain. Tissue-engineered nerve grafts, emerging as promising alternatives, still face challenges due to the lack of essential biochemical and biophysical cues for comprehensive nerve regeneration. This study introduces a Janus Mg 2+ /H 2 pump conduit, constructed with a MgH 2 @PLGA middle layer, polycaprolactone (PCL) outer layers, and a polydopamine-coated PCL (PCL@PDA) inner layer. The PCL provides structural support, while the MgH 2 @PLGA layer continuously releases Mg 2+ and H 2 as biochemical cues, driven by an acidic microenvironment and the MgH 2 -water reaction. PDA modification of the inner layer, serving as biophysical cues, further increases cell adhesion. Mg 2+ released from the conduit mitigates oxidative stress in Schwann cells and increases their expression of neurotrophic factors, while the H 2 attenuates inflammation, aiding nerve regeneration. In a rat sciatic nerve defect model, the conduit shows enhanced functional, electrophysiological, and histological recovery. These findings highlight the potential of Janus Mg 2+ /H 2 pump conduit as a promising approach for peripheral nerve defect repair by offering a conducive microenvironment.
研究领域:
神经科学
·
生物材料学
·
再生医学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Yufei Yan,Jin Wang,Wubin Wang,Chao Han,Kaili Huo,Qingyun Zhang,Ning Wang
Positively charged nanofiltration (NF) membranes are widely used to separate Li + and Mg 2+ , which play an important role in extracting lithium from salt lakes. Despite its widespread use, the polyethyleneimine-trimesoyl chloride (PEI-TMC) membrane has attracted attention due to its limited permeance and separation efficiency. To address these challenges, we introduced amine-functionalized titanium dioxide (TiO 2 -NH 2 ) nanoparticles into the interfacial polymerization (IP) reaction. The introduction of TiO 2 -NH 2 reduced the diffusion rate of PEI and formed nanoscale water channels in the polyamide (PA) layer. This modification effectively modulated the structure of the NF membrane. The NF membrane exhibited high water permeance (9.65 L·m −2 ·h −1 ·bar −1 ) and Li + /Mg 2+ selectivity ( S Li, Mg = 16.31) when 0.03 wt% TiO 2 -NH 2 was used. The DLVO theory and transition state theory showed that the introduction of TiO 2 -NH 2 improved the rejection of Li + and Mg 2+ by the membrane. Furthermore, the optimized NF membranes demonstrated excellent stability during long-term filtration and in the mixed salt solutions with varying Mg 2+ /Li + mass ratios. This work is of great significance for designing and advancing membrane materials that facilitate the efficient separation of lithium from salt lakes with high Mg 2+ /Li + mass ratios.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2024
·
IF 8.3
Jia-Shuai Chen,Jing Wang,Ji-Hong Zhang,Zhi-Yuan Guo,Pan-Pan Zhang,Xiao-Fu Guo,Jie Liu,Zhi-Yong Ji
Achieving separation of lithium and magnesium with similar radii is crucial for the current lithium extraction technology from salt lakes, which usually possess a high lithium-to-magnesium ratio. Herein, we proposed the facile sequential interfacial polymerization (SIP) approach to construct electronanofiltration membranes (ENFMs) with a bilayer charged structure consisting of a high positively charged surface and a negatively charged sublayer. The trimesoyl chloride (TMC) concentration was adjusted to enhance the −COOH content and negative charge of the polyamide sublayer to promote Li+ migration, and then the quaternized polyethylenimine was introduced to the membrane surface by the SIP process to increase the positive charge density on the surface of the ENFMs, which would block the migration of Mg2+ and enhance the Li+/Mg2+ selectivity of the ENFMs. The optimal quaternary-modified ENFMs achieved outstanding selectivity for Li+/Mg2+ (49.85) and high Li+ flux (4.10 × 10–8 mol cm–2 s–1) at a current density of 10 mA cm–2. Moreover, in simulated brines with low lithium concentration and high Mg2+/Li+ ratio, the optimal ENFMs also displayed elevated Li+/Mg2+ selectivity (>45), highlighting the substantial promise of the membranes for practical applications.
研究领域:
材料科学
·
化学工程
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2024
·
IF 8.4
Zhiyuan Zha,Tingyu Li,Ismail Hussein,Ying Wang,Song Zhao
The scarcity of lithium can be effectively addressed by extracting it from salt-lake brines. In this work, aza-crown ether (diazo-18-crown-6, DA18C6) was coupled into a polyamide (PA) network interfacial polymerized by trimesoyl chloride and polyethyleneimine (PEI) for efficient Li + /Mg 2+ separation. The embedment of DA18C6 molecule into PA network was confirmed by structural characterization and density functional theory simulation, which enhanced crosslinking degree and reduced average pore size of PA selective layer. In addition, the strong interaction between DA18C6 and Li + was proven through molecular dynamics simulation. The resulting PEI@DA18C6-PA membrane displayed a high pure water permeance of 10.4 L⋅m − 2 ⋅h − 1 ⋅bar − 1 and an excellent Li + /Mg 2+ separation factor ( S Li,Mg ) of 11.2, which was comparable with most reported Li + /Mg 2+ separation membranes . Furthermore, the PEI@DA18C6-PA membrane was employed in a three-stage NF treatment process to filtrate simulated brines containing a high Mg 2+ /Li + ratio of 57. The results demonstrated that Li + can be effectively concentrated and extracted through the membrane to obtain a permeate with an ultralow Mg 2+ /Li + ratio of only 0.03, suggesting that PEI@DA18C6-PA membrane has great application potential in lithium extraction from salt-lake brines.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Jian Lu,Chenye Dai,Shilong Li,Dong Zou,Yuqing Sun,Wenheng Jing
Similar physicochemical properties render the separation of Li + /Mg 2+ from salt lake brine difficult for two-dimensional (2D) membranes. Herein, ultraefficient Li + /Mg 2+ separation was achieved under the influence of an electric field using MXene/carbon nanotube (CNT) membranes developed on tubular ceramic substrates via thermal crosslinking. Crosslinking reactions between CNTs and MXene yielded well–intercalated CNTs between MXene nanosheets, forming antiswelling MXene/CNT membranes (MCMs) (interlayer spacing: 8.04 Å) suitable for Li + /Mg 2+ separation. At 2.8 V applied voltage, the MCMs exhibited Li + flux of 0.0491 mol m −2 h −1 and high Li + /Mg 2+ selectivity of 54.5, which outperform existing state–of–the–art 2D membranes. Specifically, under a positive electric field, Li + with a small hydration diameter and low hydration energy permeated through the membrane nanochannels more easily than Mg 2+ , increasing and decreasing Li + and Mg 2+ flux, respectively. Additionally, Mg 2+ retention was enhanced via the complexation of enriched Mg 2+ with –OH and –COOH on the membrane surface. The MXene membrane surface was thus reconfigured to be positively charged, inducing effective Mg 2+ rejection. This study offers a novel and practical approach for efficiently separating Li + /Mg 2+ as well as monovalent/multivalent ions.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2025
·
IF 9
Yufei Yan,Jin Wang,Wubin Wang,Chao Han
Positively charged polyethyleneimine (PEI) nanofiltration (NF) membranes exhibit great potential for Li + /Mg 2+ separation. However, the dense nature of the polyamide (PA) layer presents a challenge in breaking through the permeance bottleneck, significantly hindering its further application. In this study, 1-(2-aminoethyl)piperazine (AEP) was first incorporated into the PEI solution as a structural regulator to adjust the microstructure of the PA separation layer. The structure of the PA selective layer was fine-tuned with the incorporation of AEP, enlarging the spacing between the long-chain molecules of PEI, and established hydrogen bonding interactions with PEI. This led to the generation of Turing structures on the membrane surface, which enhanced permeance. Meanwhile, the primary amine groups in AEP were protonated in water, aiding in boosting positive membrane charge and subsequently elevating its rejection capability for divalent cations. The ingenious combination of large molecule PEI and small molecule AEP served a dual purpose in promoting the membrane construction and performance. The optimized PEI/AEP-TMC NF membrane exhibited high pure water permeance (11.24 L m −2 h −1 bar −1 ) and excellent Li + /Mg 2+ selectivity ( S Li, Mg = 24.59), while also achieving higher Li purity and Li recovery. Insights into the remarkable performance of the modified membranes were gained through the transition state theory. Additionally, the internal stress generated in the NF process was determined by utilizing the principles of thin plate theory, revealing that the NF membrane possesses good pressure resistance and maintains stable operation at pressures up to 9 bar. This study demonstrates the capability of PEI/AEP-TMC NF membranes for Li + /Mg 2+ separation and offers a novel aqueous phase monomer for the preparation of NF membranes specifically for Li + /Mg 2+ separation.
研究领域:
材料科学
·
化学工程
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
DESALINATION
·
2026
·
IF 9.9
Chun-Xu Zhang,Yan-Yan Chen,Ren-Jie Fan,Yu-Xuan Sun,Xiaohu Wang,Fujun Xiong,Yong Wang,Mei-Ling Liu,Shi-Peng Sun,Weihong Xing
Electric field-assisted nanofiltration (ENF) has emerged as a promising technology for Mg 2+ /Li + separation from salt lake brines. However, integrating ENF process with widely used negatively charged membranes induces a non-uniform distribution of reconstructed positive charge. This leads to reduced separation efficiency under high feed concentrations due to charge shielding effects. To overcome this limitation, we developed a strategy employing a positively charged nanofiltration (NF) membrane under an applied electric field. This configuration facilitates both the dehydration of hydrated Li + and a more uniform distribution of positive charges on the membrane surface. The optimized system demonstrated a remarkable separation performance, achieving nearly 100% rejection of Mg 2+ and − 176% rejection of Li + . The separation factor ( S Li, Mg ) represents a 162-fold improvement over the system without an electric field. The ENF process successfully separated Mg 2+ and Li + even in real Yiliping salt lake brine. Furthermore, the permeate stream containing high-purity Li + enabled the production of battery-grade Li₂CO₃ with 99.9% purity. This study demonstrates a pragmatic and efficient approach for Mg 2+ /Li + separation, showcasing considerable promise for high-purity Li + extraction from salt lakes.
✓ 已验证
产品关联
DOI
高影响因子
Nano-Micro Letters
·
2026
·Vol. 18
·期 1
·126
·
IF 36.3
Zhang Zixuan,Kong Yan,Li Runlai,Yue Xiaolin,Deng Hao,Zheng Yu,Zhang Sui,Zhang Runnan,Jiang Zhongyi
Covalent organic framework (COF) scaffold membranes with gate-lane nanostructure were prepared.
The gating layer affords high rejection to Mg 2+ and thus high Li + /Mg 2+ selectivity. The permeating layer bearing Li + lanes and Cl − lanes facilitates Li + transport and thus high Li + permeability.
The COF scaffold membrane exhibits the true selectivity of 231.9 with Li + enrichment of 120.2% at the Mg 2+ /Li + mass ratio of 50, exceeding the ideal selectivity of 80.5.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2026
·
IF 5.8
Yuancheng Yao,Jinhuan Yao,Jiqiong Jiang,Xin Tang,Jianwen Yang,Yanwei Li
Developing bifunctional materials with concurrent electrochromic and electrochemical energy storage capabilities is crucial for advancing the construction of energy-saving smart windows, smart sensors, implanted displays, and electronic skins. Herein, a layered V 2 O 5 · n H 2 O thin film is fabricated through a facile electrodeposition method with V 2 O 5 sol as electrolyte, and its Mg 2+ storage and electrochromic performances are explored for the first time. This layered V 2 O 5 film exhibits outstanding Mg 2+ storage performance, delivering an areal specific capacity of 17 μAh cm −2 at 0.5 mA cm −2 , showing no capacity decay during 500 cycles, and exhibiting superior rate performance. It achieves an optical contrast (Δ T ) of 64.63% at 769 nm wavelength (between orange-red and dark green) and a rapid switching speed. Notably, the color transition exhibits a distinct potential dependence and high optical distinguishability: it reversibly switches between green, orange, and red hues at discrete potential points during the electrochemical cycling process. The structure/performance relationship of the film is analyzed via in situ Raman, ex situ XRD, XPS, and DFT calculations. This study provides clues for developing Mg 2+ -intercalation-based electrochromic energy storage bifunctional materials.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2019
·
IF 7.015
Chengyi Zhang,Yingxin Mu,Wen Zhang,Song Zhao,Yuxin Wang
Developing effective technologies for extraction of Li + from salt-lake brines with high Mg 2+ /Li + ratios is paramount for sustainable utilization of lithium resources in electric vehicle and nuclear energy industries. In this work, hybrid membranes were prepared with polyvinyl chloride matrix and six metal−organic frameworks (MOFs@PVC) to separate Li + from Mg 2+ in solution. The effects of pore size sieving and sulfonation of the MOFs on the Li + /Mg 2+ separation efficiency were evaluated using the current-voltage ( I – V ) method, and the stability of the MOFs@PVC membranes was systematically evaluated. The loading amount of MOFs and the thickness of the membranes were also optimized for Li + transport and selectivity. The results show that the small pore size and sulfonation of MOFs are benefit to separate Li + from Mg 2+ . Specifically, PVC-based hybrid membrane containing HSO 3 -UiO-66 shows the highest selectivity for Li + (Li + /Mg 2+ > 4), with the diffusion coefficient of 2.0×10 -10 cm 2 s -1 for Li + and 4.67×10 -11 cm 2 s -1 for Mg 2+ . This study highlights the stable sulfonated Zr-based MOF with suitable pore sizes for membrane-based Li + /Mg 2+ separation, and provides a potential alternative for recovering lithium from salt-lake brines.
研究领域:
材料科学
·
化学工程
·
环境科学
✓ 已验证
产品关联
DOI
高影响因子
Bioactive Materials
·
2021
·
IF 14.593
Zhaoyuan Guo,Zhuangzhuang Zhang,Nan Zhang,Wenxia Gao,Jing Li,Yuji Pu,Bin He,Jing Xie
Bacterial infection is a vital factor to delay the wound healing process. The antibiotics abuse leads to drug resistance of some pathogenic bacteria. Non-antibiotic-dependent multifunctional biomaterials with accelerated wound healing performance are urgently desired. Herein, we reported a composite antibacterial hydrogel PDA-PAM/Mg 2+ that shows excellent self-healing and tissue adhesive property, and photothermal antibacterial functions for accelerating wound healing. The gel was composed of polyacrylamide (PAM), polydopamine (PDA), and magnesium (Mg 2+ ) and prepared via a two-step procedure: an alkali-induced dopamine pre-polymerization and followed radical polymerization process. The composite gel shows excellent tissue adhesiveness and Mg 2+ -synergized photothermal antibacterial activity, inducing a survival rate of 5.29% for S. aureus and 7.06% for E. coli after near infrared light irradiation. The composite hydrogel further demonstrated efficient bacteria inhibition, enhanced wound healing and collagen deposition in a full-thickness skin defect rat model. Together, the PDA-PAM/Mg 2+ hydrogel presents an excellent wound dressing with excellent tissue adhesion, wound healing, and antibacterial functions.
研究领域:
生物材料学
·
医学
·
药理学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
JOURNAL OF MEMBRANE SCIENCE
·
2022
·
IF 10.53
Xufei Liu,Yuxi Feng,Yunxia Ni,Huawen Peng,Shaoping Li,Qiang Zhao
Nanofiltration represents an efficient technology for mono/divalent ions separation, such as Mg 2+ /Li + mixtures which are crucial for lithium extraction from salt lakes. This work shows that charge intensification of loose structure nanofiltration membranes is an effective way to reconcile high flux with Mg 2+ /Li + selectivity. A new electrolyte monomer (QTHIM) containing quadruple imidazolium and hydroxyl groups was synthesized to react with residual acyl chloride groups on the nascent polyethyleneimine-based polyamide membranes (PEI-TMC), leading to the formation of a high-permeance nanofiltration membrane (PEI-TMC-QTHIM). The modified membrane highlights loose structures combined with enhanced positive charge, exhibiting high water permeance (∼33 L m −2 h −1 bar −1 ), good MgCl 2 rejection (∼92%) and high flux to 100 Mg 2+ /Li + ratio mixture (∼170 L m −2 h −1 ). Notably, flux of the modified membrane is ca. 6 times as high as that of the nascent membrane.
研究领域:
材料科学
·
环境工程
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）