POLYMER DEGRADATION AND STABILITY
·
2024
·
IF 6.3
Mei Wan,Congling Shi,Lei Chen,Lei Deng,Yueping Qin,Honglei Che,Jingyun Jing,Junyi Li,Xiaodong Qian
Ammonium polyphosphate (APP) is the most commercially valuable phosphorus-based flame retardant, but poor interaction with the polymer interface limits the flame-retardant efficiency. In this work, a new type of multi-layered nanomaterial coating APP (APP-PEI@MXene@ZIF-67) was prepared and introduced into thermoplastic polyurethane (TPU) polymers by a simple and green assembly strategy. The effects of different loading shells of modified APP on the flame retardancy of TPU composites were investigated, as well as their gas/condensed phase thermal degradation products and their flame-retardant mechanisms. The results showed that APP-PEI@MXene@ZIF-67 was more favorable for catalytic char formation than APP, and the residual char formed by its composites was denser and more continuous. Compared with the pure TPU, the pHRR, THR, pSPR, and TSP of TPU/APP-PEI@MXene@ZIF-67–2BL composites were decreased by 72.75 %, 87.25 %, 59.58 %, and 85.97 %, respectively, which significantly reduced the heat and smoke release during the combustion process. The gas-phase and condensed-phase flame retardant mechanisms synergized to construct a possible approach to address the fire risk and heat/smoke hazards of TPUs and promote the extensive application of TPU polymers.
研究领域:
材料科学
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高分子科学
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消防安全工程
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DOI
高影响因子
JOURNAL OF RAMAN SPECTROSCOPY
·
2021
·Vol. 53
·期 2
·211-221
·
IF 3.133
Nan Jia,Yinran Xiong,Ying Wang,Siqian Lu,Ruoqiu Zhang,Yan Kang,Yiping Du
A label-free and novel surface-enhanced Raman scattering (SERS) method has been studied to rapidly detect common fish pathogenic bacteria ( Escherichia coli , Vibrio anguillarum , Vibrio harveyi , Edwardsiella piscicida , and Pseudomonas plecoglossicida ). The marriage of magnetic nanospheres (Fe 3 O 4 ) with polyethylenimine (PEI) could trigger surface charge modifications of Fe 3 O 4 , making it effective to capture negatively charged bacteria. After the rapid bacterial capture procedure within 10 min, Au@Ag core-shell bimetallic nanoparticles served as hotspot providers to facilitate the enhancement of biological Raman signals. The results demonstrated that the minimum detection limit of E. piscicida could be as low as 10 5 cfu/ml. The peak intensity at 1628 cm −1 ( E. piscicida ) showed a linear relationship with the logarithm of the bacterial concentration ( R 2 = 0.997). A mimic test was conducted by spiking E. piscicida into tap water. Linear discriminant analysis (LDA) was also harnessed to classify different types of fish bacteria. And the positive rates of the training set and the prediction set were 100% and 80%, respectively. The whole experimental procedure only takes 20 min. This method opens a new avenue for the rapid detection and identification of fish pathogenic bacteria.
研究领域:
水产养殖学
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生物分析化学
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纳米技术
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DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2022
·
IF 9.136
Rui Ding,Qiuchen Wang,Xuehua Ruan,Yan Dai,Xiangcun Li,Wenji Zheng,Gaohong He
1D nanotube (HNT) based MMM presents high CO 2 permeation due to its long and hollow structure. However, the improvement of selectivity is still challenging. In this study, small PEI molecules with abundant amino groups were introduced into the nanocages of ZIF-8 HNTs to construct facilitated CO 2 transmission channel with low resistance. In the PEI@ZIF-8 HNTs, the –NH 2 groups can facilitate CO 2 transport in presence of H 2 O, resulting in an improvement in both CO 2 permeability and selectivity. Second, the introduction of PEI into the nanocages of ZIF-8 can adjust the effective sieving size to enhance CO 2 selectivity. Third, the hydrogen bond between PEI and Pebax can strengthen the interfacial compatibility, further improving CO 2 /N 2 selectivity of the MMMs. Finally, the 1D hollow structure of PEI@ZIF-8 HNTs provides CO 2 molecules with low-resistance and fast transport channel, enhancing the CO 2 permeability. Consequently, both the high CO 2 permeability and the high CO 2 /N 2 selectivity are acquired by the versatile filler of PEI@ZIF-8 HNTs. PEI@ZIF-8 HNTs based MMM at filler loading of 7 wt% under dry mixed gas, presents CO 2 permeability of 177 Barrer and CO 2 /N 2 selectivity of 72, which are 40% and 10.8% higher than those of ZIF-8 HNTs based MMM, respectively. Moreover, the permeability of CO 2 and the selectivity of CO 2 /N 2 reach 306 Barrer and 79 respectively under the wet mixed gas, which is far beyond the Robeson upper bound in 2008 and exceeds the McKeown upper bound in 2019. The proposed PEI@ZIF-8 HNTs are believed to be promising filler for MMMs based CO 2 capture.
研究领域:
材料科学
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化学工程
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环境科学
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DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2021
·
IF 5.909
Yan Li,Shu Xiong,Xiangying Tang,Hao Wu,Chao Han,Ming Yi,Yan Wang
Salt accumulation is inevitable in the conventional textile wastewater treatment , which hardly realize the effectively remove of dye and recover of water. Loose nanofiltration (NF) membrane with highly hydrophilic surface and loose structure has been demonstrated as an optimal choice for efficient dye/salt separation. This study develops a loose NF membrane via the layer-by-layer (LbL) assembly of highly-branched sulfonated polyethyleneimine (SPEI)/polyethyleneimine (PEI) and mussel-inspired post-crosslinking. Different molecular weights of highly-branched SPEI are synthesized. Effects of LbL assembly and cross-linking process, SPEI molecular weight and crosslinker type are investigated systematically. It is found that the membrane prepared with the assembly of SPEI10k/PEI and crosslinked by catechol exhibits low roughness (Ra = 3.56 nm), high hydrophilicity (WCA = 44.07°) and negatively-charged membrane surface (ζ = −16.39 mV). As a result, the membrane achieves an ultrahigh permeability (~ 36.89 LMH/bar), excellent dyes retention (> 99.37% to Congo red), as well as low rejection to salts (2.47% to NaCl). The novel loose NF membrane developed in this work therefore shows a promising prospect in practical industrial textile wastewater treatment.
研究领域:
环境工程
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材料科学
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水处理
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产品关联
DOI
高影响因子
JOURNAL OF FLUORESCENCE
·
2024
·
IF 2.6
Zhu Hongmei,Yang Bo,Niu Yang,Huang Yongjiu
Laryngeal cancer, a common malignant respiratory tumor, is primarily treated through surgery. However, challenges such as recurrence, metastasis, and drug resistance persist. In recent years, multifunctional drug delivery systems (DDS) based on nanoparticles have shown great potential in improving drug loading and release. We developed a biocompatible core-shell nanoparticle system with a zinc-based metal-organic framework (MOF) as the core, named CP1. The shell, composed of polyethyleneimine (PEI), folic acid, and calcium carbonate, forms a composite called CaCO 3 -PEI-FA. This system enhances biocompatibility and increases the efficacy of biomedical applications. Encapsulating CP1 within the CaCO 3 -PEI-FA shell allows for the targeted delivery of the anticancer drug doxorubicin (DOX) to laryngeal cancer cells (Hep-2), resulting in the CaCO 3 -PEI-FA@CP1@DOX system. The CaCO 3 -PEI-FA composite exhibits strong fluorescence with a peak around 350 nm, confirming successful synthesis and demonstrating its potential as a bioimaging probe. Importantly, the nanoparticle system without DOX showed low toxicity to normal human skin fibroblasts (HSF). In vitro cytology experiments revealed a 38% inhibition rate of Hep-2 cells after 24 h, highlighting the nanocomposite’s significant potential in inhibiting laryngeal cancer cell proliferation and inducing apoptosis, underscoring its promise in targeted laryngeal cancer therapy.
研究领域:
纳米技术
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癌症研究
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药物递送系统
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
Journal of Coatings Technology and Research
·
2023
·Vol. 20
·期 3
·979-994
·
IF 2.3
Liu De,Wang Huming,Dong Xuxu,Liu Xiaodan,Dosta Sergi,Zhang Chao,Cao Pan
Marine fouling can cause a series of hazards in the marine industrial field, and the traditional antifouling methods do not fulfill the green antifouling requirement. Herein, a novel DA/PEI/SiO 2 /antibacterial peptide antifouling coating was prepared by a multi-modification approach. Initially, the nanocoatings were prepared by depositing DA, PEI, and SiO 2 on the dopamine (DA)-modified 304 stainless steel (SS) surface, and finally, the DA/PEI/SiO 2 /AMPs composite coatings were prepared by grafting antimicrobial peptides (AMPs). The surfaces of SS before and after modification were characterized by Fourier transform infrared spectrometer (FTIR), X-ray photoelectron spectrometer (XPS), field emission scanning electron microscopy (SEM), contact angle measurement, and 3D optical profilometer. SSN-1 cells were used to evaluate the cytocompatibility of the modified surface. The results revealed that the cells cultured on the modified surface still maintained a good adhesion morphology, demonstrating the superior cytocompatibility of the composite coating. The anti-biofilm and antimicrobial properties of the modified samples were evaluated using Vibrio natriegens . The antibacterial efficiency of SS-DA/PEI/SiO 2 surfaces before and after AMPs modification reached 78.39 and 95.90%, and anti-biofilm efficiency of AMPs modified surface achieved 72.87% corresponding to 44.19% of SS-DA/PEI/SiO 2 . The successful grafting of AMPs improved the antibacterial and anti-biofilm properties of the modified sample surfaces. Electrochemical and stability tests indicated that the modified sample surfaces exhibited excellent corrosion resistance and antifouling stability properties. This research could provide a novel green anti-fouling and anti-corrosion strategy for the marine industry and other related fields.
研究领域:
材料科学
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表面工程
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生物医学工程
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海洋技术
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产品关联
DOI
高影响因子
Journal of Materials Chemistry B
·
2014
·Vol. 2
·期 13
·1825-1837
·
IF 0
Changcan Shi,Fanglian Yao,Jiawen Huang,Guoliang Han,Qian Li,Musammir Khan,Yakai Feng,Wencheng Zhang
Herein, we developed a novel biodegradable gene carrier for rapid endothelialization of endothelial cells (ECs) in vitro. Three triblock amphiphilic copolymers, methoxy-poly(ethylene glycol)-block-poly(3(S)-methyl-2,5-morpholinedione-co-glycolide)-graft-polyethyleneimine (mPEG-b-P(MMD-co-GA)-g-PEI) with different 3(S)-methyl-2,5-morpholinedione and glycolide contents were synthesized. Microparticles (MPs) were obtained via self-assembly of these copolymers. The hydrophobic core composed of P(MMD-co-GA) segments provide crosslinking points for numbers of PEG and short PEI chains to form a highly hydrophilic and positively charged corona/shell of MPs. Using these MPs, potential genes (ZNF580) for rapid endothelialization were efficiently transported into EA.hy926 cells. Because of the hydrophilic PEG chains and low molecular weight PEI in the triblock copolymers, the cytotoxicity of these MPs and their complexes with pEGFP–ZNF580 was decreased significantly. The transfection efficacy of MPs/pEGFP–ZNF580 complexes was as high as Lipofectamine™ 2000 reagent to EA.hy926 cells in vitro. The proliferation and migration of EA.hy926 cells were improved greatly by the expression of pEGFP–ZNF580 after 60 hours. Our results indicated that the mPEG-b-P(MMD-co-GA)-g-PEI based MPs could be a suitable non-viral gene carrier for ZNF580 gene to enhance rapid endothelialization.
研究领域:
生物医学工程
·
基因治疗
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材料科学
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细胞生物学
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产品关联
DOI
PubMed
Algal Research-Biomass Biofuels and Bioproducts
·
2017
·
IF 3.994
Yangyang Yang,Jun Hou,Peifang Wang,Chao Wang,Lingzhan Miao,Yanhui Ao,Yi Xu,Xun Wang,Bowen Lv,Guoxiang You,Zijun Yang
Heteroaggregation between magnetic nanoparticles (MNPs) and cells is a crucial precondition for the harvesting and separation of algae from the aquatic environment . However, separation mechanisms have not been fully elaborated in previous studies, especially regarding cyanobacteria coated with extracellular polymeric substances (EPS). The present study was conducted to investigate the interaction between PEI-coated iron-oxide nanoparticles (IONPs) and M. aeruginosa as a function of cell type (FACHB-1343 and FACHB-905) and cells with/without extracellular polymeric substances (EPS). The results demonstrated that harvesting efficiency (HE) varied with the different cell types with/without EPS surrounding the cyanobacteria. The PEI-coated IONPs showed higher HE for M9 than for M1 with the same mass ratio of NPs/cyanobacteria. Furthermore, EPS significantly affected the HE because of their heterogeneous composition, which was interpreted by spectral analysis and the DLVO theory. Overall, this study provides guidance on cyanobacteria harvesting with different environmental conditions when employing magnetic separation technology.
研究领域:
环境科学
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纳米技术
·
水生生物学
·
化学工程
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产品关联
DOI
高影响因子
Journal of Saudi Chemical Society
·
2023
·
IF 5.6
Jiafeng He,Jumei Li
Developing sensitive, reliable, and robust surface-enhanced Raman spectroscopy (SERS) substrates relies heavily on fabricating a substantial number of hot spots. In this study, we present a straightforward method for creating Ag@PEI/Ag core-satellite nanocomposites. Large Ag nanospheres serve as the cores, and smaller Ag nanoparticles are electrostatically assembled around them through the introduction of polyethyleneimine (PEI). This assembly process generates numerous hot spots not only between two Ag satellites but also between the inner Ag core and Ag satellites, thanks to the sub-nm PEI interlayer. The nanocomposites exhibit great potential for SERS analysis, enabling effective sensing of various organic pollutants, such as thiram and ciprofloxacin, using a portable Raman spectrometer. Notably, these nanocomposites obtain an exceptional detection limit of as low as 10 −8 M for them, which falls below the safety level set by the United States Environmental Protection Agency. Additionally, the substrates demonstrate excellent uniformity, reproducibility and storing stability. Consequently, the Ag@PEI/Ag core-satellite nanocomposites hold great promise as efficient SERS platforms for reliable and highly sensitive monitoring of food safety and environmental analysis.
研究领域:
纳米技术
·
分析化学
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环境科学
·
食品安全
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2023
·
IF 5.8
Ziwei Liang,Yuhui Wang,Jiapu Wang,Tao Xu,Shilong Ma,Qi Liu,Liqin Zhao,Yan Wei,Xiaojie Lian,Di Huang
Ferroptosis is a novel form of regulated cell death induced by iron-dependent lipid peroxidation imbalance. It has emerged as a promising antitumor therapeutic strategy in recent years. In this work, we successfully synthesized a complex magnetic nanocube Fe 3 O 4 modified with PEI and HA by the thermal decomposition method. While loading a ferroptosis inducer RSL3 inhibited cancer cells through the ferroptosis signal transduction pathway. The drug delivery system could actively target tumor cells through an external magnetic field and HA-CD44 binding. Zeta potential analysis showed that Fe 3 O 4 [email protected] nanoparticles were more stable and uniformly dispersed in tumor acidic environment. Moreover, cellular experiments demonstrated that Fe 3 O 4 [email protected] nanoparticles could significantly inhibit the proliferation of hepatoma cells without a cytotoxic effect on normal hepatic cells. In addition, Fe 3 O 4 [email protected] played a vital role in ferroptosis by accelerating ROS production. The expression of ferroptosis-related genes Lactoferrin, FACL 4, GPX 4 and Ferritin was significantly suppressed with increasing treatment of Fe 3 O 4 [email protected] nanocubes. Therefore, this ferroptosis nanomaterial has great potential in Hepatocellular carcinoma (HCC) therapy.
研究领域:
纳米技术
·
癌症生物学
·
药学
·
分子生物学
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生物医学工程
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产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF ADHESION AND ADHESIVES
·
2020
·
IF 2.671
Weijie Li,Lin Sang,Xigao Jian,Jinyan Wang
Increasing interest in 3D-printed high-performance polymers is observed due to their excellent mechanical properties and high resistance to chemical and thermal degradation. One of the ongoing challenges is to achieve sufficient joint strength because of the inertness of thermoplastics . In the current work, effects of surface treatment on shear bond strength of 3D-printed samples were focused and assessed. First, polyetherimide (PEI), polyether ether ketone (PEEK) and PEEK/CF(carbon fiber) as adherend were produced via FDM 3D printing . Then, sanding or atmospheric plasma treatments were carried out to improve the surface wettability of the 3D-printed specimens. Significantly, reduction in surface roughness was observed in sanding treated specimens, while nearly no change occurred in plasma-treated counterparts. However, surface free energy and wettability were greatly improved after plasma treatment. Single lap-shear tests and failure mode for PEI, PEEK and PEEK/CF using two different adhesives (film and liquid) were investigated, and the effect of surface treatment on bond strength was further compared. Results suggested that liquid adhesive contributed higher joint strength for surface-treated specimens in comparison to film adhesive . Besides, atmospheric plasma treatment is more efficient and safer method for 3D-printed PEEK and PEEK/CF, achieving a higher joining strength.
研究领域:
材料科学
·
机械工程
·
表面工程
·
3D打印
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产品关联
DOI
高影响因子
ANALYTICA CHIMICA ACTA
·
2022
·
IF 6.911
Mengyang Li,Baoshan He,Haoyang Yan,Lingling Xie,Xiaoyu Cao,Huali Jin,Min Wei,Wenjie Ren,Zhiguang Suo,Yiwei Xu
A novel ultrasensitive electrochemical aptasensor was proposed for quantitative detection of Cd 2+ . To this end, flower-like polyethyleneimine-functionalized molybdenum disulfide-supported gold nanoparticles (PEI-MoS 2 [email protected] NPs) were used as substrates for the modification of bare gold electrodes (AuE). PEI-MoS 2 [email protected] NPs not only possessed excellent biocompatibility and large specific surface area to enhance the cDNA loading capacity, but also possessed good conductivity to accelerate the electron transfer rate. Furthermore, the preparation of dendritic platinum-palladium nanoparticles (PtPd NPs) can effectively load Cd 2+ -aptamer. Thionine and aptamers were loaded onto PtPd NPs to construct Thi-PtPd NPs-aptamer signal probes. The signal probes were captured by the cDNA immobilized on the electrode via base-pairing rule, and the signal of Thi was detected by differential pulse voltammetry (DPV). In the presence of Cd 2+ , aptamer-cDNA unwinded, and the combination of aptamer and Cd 2+ caused the signal probes to fall off the electrode and the electrical signal decreases. Under optimal conditions, the proposed aptasensor exhibited a linear relationship between the logarithm of Cd 2+ concentration and the current response over a wide range of 1 × 10 −3 nM to 1 × 10 2 nM, with a detection limit of 2.34 × 10 −4 nM. At the same time, the aptasensor was used to detect Cd 2+ in tap water with satisfactory results. In addition, it has good reproducibility, selectivity and stability, and has broad application prospects in heavy metal analysis.
研究领域:
分析化学
·
环境科学
·
纳米技术
·
电化学
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产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）