SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Xia Gao,Guangming Sun,Xinke Wang,Xiaodong Lin,Shuo Wang,Yaqing Liu
As a vital signaling molecules, hydrogen sulfide (H 2 S) with abnormal concentrations is correlated with many diseases. Therefore, development of novel assays for quantitative and selective detection of H 2 S is important. Herein, we synthesized a host-guest metal-organic framework (MOF), i.e., RhB/UiO-66-N 3 (here, RhB means rhodamine B) by a mildly and simply way, as reaction-based ratiometric fluorescent nanosensor for selective detection and intracellular imaging of H 2 S. In the presence of H 2 S, the RhB/UiO-66-N 3 exhibits dual emissions at 425 nm and 575 nm under irradiation of single excitation wavelength. The blue fluorescence at 425 nm (F 425 ) is attributed to the H 2 S-mediated biorthogonal reduction of azide to amine, and the red fluorescence at 575 nm (F 575 ) originating from RhB is served as an internal reference. With increasing concentrations of H 2 S, the intensity of blue fluorescence increases while the intensity of red fluorescence has no obvious change. With F 425 /F 575 as readout, turn-on and ratiometric fluorescence detection of H 2 S was achieved with good selectivity and sensitivity. Interestingly, RhB/UiO-66-N 3 can be tuned from microscale to nanoscale sizes, and endows high stability under physiological conditions. The exogenous and endogenous H 2 S in live cells has been further targeted and imaged, demonstrating its considerable potential for extensive applications.
研究领域:
生物化学
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医学
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材料科学
✓ 已验证
DOI
高影响因子
ANALYTICAL SCIENCES
·
2024
·Vol. 40
·期 6
·1081-1087
·
IF 1.8
Mei Xuqiao,Zeng Zhenhua,Xu Wenxin,Yang Huicong,Zheng Yuanhai,Gao Haimin,Wu Chuncai,Zheng Yanping,Xu Qiaoli,Wang Guowei,Xu Yuhuang,Wu Ayang
CA125 (carbohydrate antigen 125) is an important biomarker of ovarian cancer, so developing effective method for its detection is of great significance. In the present work, a novel sandwich-like electrochemical immunosensor (STEM) of CA125 was constructed by preparing nanoribbon-like Ti 3 C 2 T x MXenes (Ti 3 C 2 T x NR) to immobilize primary antibody (PAb) of CA125 and UIO-66-NH 2 MOFs structure to immobilize second antibody (SAb) and electroactive toluidine blue (Tb) probe. In this designed STEM assay, the as-prepared Ti 3 C 2 T x NR nanohybrid offers the advantages in large surface area and conductivity as carrier, and UIO-66-NH 2 provided an ideal platform to accommodate SAb and a large number of Tb molecules as signal amplifier. In the presence of CA125, the peak currents of Tb from the formed STEM structure increase with the increase of CA125 level. After optimizing the related control conditions, a wide linear range (0.2–150.0 U mL −1 ) and a very low detection limit (0.05 U mL −1 ) of CA125 were achieved. It’s thus expected the developed STEM strategy has important applications for the detection of CA125. Graphical abstract
研究领域:
生物医学工程
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分析化学
·
肿瘤学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Peng Li,Yuxiu Sun,Zhengqing Zhang,Zhenjie Gu,Zhihua Qiao,Chongli Zhong
Metal-organic frameworks (MOFs) have driven the development of polycrystalline membranes in the field of gas separation owing to the strong adsorption-desorption behavior and stable framework structure. However, the poor heterogeneous bonding ability between crystals and the substrate leads to the unsatisfactory gas separation as well as low stability of MOF membranes, especially in the humid environment . Herein, we prepared a thin and defect-free UiO-66 membrane by a crystal heterogeneous nucleation assisted growth strategy for efficient CO 2 /N 2 separation. The addition of small amount of water in the precursor solution promoted the crystal nucleation process on the substrate surface. Meanwhile, the smooth PDMS interlayer guaranteed the heterogeneous well-intergrown of crystals into thin UiO-66 membranes, and provided a hydrophobic environment. Therefore, the dense UiO-66 membrane with a small thickness exhibited a high CO 2 permeance (177.4 × 10 −9 mol·m −2 ·s −1 ·Pa −1 ) with moderate CO 2 /N 2 selectivity (24.3) under humid conditions. Furthermore, the prepared membrane demonstrated excellent renewable performance after dehumidification at high temperature, and maintained good hydrothermal stability during long-term operation under the humid environment. This work provides a new insight for the design of high-quality MOF membranes and promotes the development of MOF membranes in practical gas separation process.
研究领域:
材料科学
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化学工程
·
气体分离技术
✓ 已验证
产品关联
DOI
高影响因子
Materials Science and Engineering B-Advanced Functional Solid-State Materials
·
2021
·
IF 4.051
Hailin Tian,Yan Gu,Houle Zhou,Yingping Huang,Yanfen Fang,Ruiping Li,Changcun Tang
In this work, bismuth bromideoxide (BiOBr), a typical visible-light photocatalyst , was coated with Zr-based MOFs (UiO-66) to prepare the BiOBr@UiO-66 photocatalysts with different mole ratios by the solvothermal method. The core–shell BiOBr@UiO-66 photocatalysts with abundant activated sites was obtained due to the modification of UiO-66 on the surface of BiOBr. The structure and properties of the BiOBr@UiO-66 photocatalysts were characterized by several methods. The 30% BiOBr@UiO-66 photocatalysts exhibited the biggest photodegradation rate constant (k = 0.0669 min −1 ) for RhB under visible-light irradiation than pure BiOBr (k = 0.0281 min −1 ) and UiO-66 (k = 0.0041 min −1 ). Additionally, the 30% BiOBr@UiO-66 photocatalysts exhibited the enhanced photocatalytic activity and stable recyclability due to the effective electron-hole separation and synergistic effect. The photocatalytic mechanism of the BiOBr@UiO-66 photocatalysts for RhB, which contained a photosensitization process, was discussed with the trapping experiment of active species and the proposed energy band alignments.
研究领域:
材料科学
·
环境科学
✓ 已验证
DOI
高影响因子
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
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2024
·
IF 6.9
Dawei Lan,Huiwen Zhu,Jianwen Zhang,Fan Wang,Yueying Zheng,Zeyu Guo,Gang Yang,Mengxia Xu,Tao Wu
Metal-organic frameworks (MOFs) is a promising material that can be used in many fields, including environmental remediation. In this work, a novel adsorbent was successfully prepared by doping the Co element into the framework of UiO-66 with an in-situ oil bath synthesis. This modification ensured that the materials retained relatively good crystallinity. The Co-doping process had a major impact on the particle size and morphology of the original MOFs. The CoUiO-2 exhibited larger surface area and pore size than pristine UiO-66. Accordingly, the maximum adsorption amount of malachite green (MG) on CoUiO-2 (628.93 mg/g) was significantly larger compared with UiO-66 (343.64 mg/g), which was due to more active adsorption sites. In addition, the CoUiO-2 also showed a superior adsorption capacity on rhodamine B (RhB) (1106.22 mg/g). The adsorption process was well described by both the pseudo-second order and Langmuir models, indicating it was dominated by chemisorption and the adsorbent had a homogeneous surface area for adsorption. Therefore, the CoUiO-2 material could be a promising adsorbent for wastewater treatment . This work can provide an important insight into the modification of MOF materials and identify further opportunities to promote the adsorption performance in environmental remediation.
研究领域:
环境科学
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材料科学
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2024
·
IF 8.1
Jiahe Chen,Yingying Zhang,Xin Guo,Yiyang Qiao,Ping Yu
Artemisinin (Art) is the primary therapies for plasmodium falciparum malaria. However, it is very cumbersome to extract artemisinin from the plant Artemisia annua L. Herein, a novel defect-type UiO-66 structure was proposed, which can adsorb artemisinin through effective sites provided by ‘template molecules’. At the same time, the delayed phase inversion technology was used to prepare the loofah membrane to make the defect-type UiO-66 uniformly dispersed in the pores. In addition, the inside of the biomass loofah membrane had good mechanical properties and loofah membrane wrapped with polyacrylonitrile (PAN) can make Art solution evenly dispersed in each channel, greatly improving the utilization rate of defect-type UiO-66. The defect-type UiO-66 and the UiO-66-D@loofah membrane were characterized using various methods, including SEM, EDS, FT-IR, XRD, contact angle, and mechanical performance analyses. Compared with the static adsorption behavior of powder and loofah membrane, it was found that the adsorption performance presented an optimal adsorption capacity (56.548 mg g −1 ) at the flow rate of 5 mL min −1 , which was better than that of powder (27.096 mg g −1 ) as well as the static loofah membrane (33.127 mg g −1 ). The structural design of the membrane has provided a new solution for the extraction of Art from Artemisia annua L.
研究领域:
材料科学
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药物提取
·
生物工程
✓ 已验证
产品关联
DOI
高影响因子
Small
·
2024
·Vol. 20
·期 34
·2401914
·
IF 13
Zhaohui Fang,Xiaoyang Yue,Quanjun Xiang
Metal halide perovskite quantum dots (QDs) are widely studied in the field of photocatalytic CO 2 due to their strong light absorption and long carrier migration length. However, it can not exhibit high catalytic performance because of the radiative recombination and the lack of effective catalytic sites. Metal organic frameworks (MOFs) encapsulated QDs can not only solve the aforementioned problems, but also maintain their own unique characteristics with ultra-high specific surfaces area and abundant metal sites. In this work, lead-free bismuth-based halide perovskite QDs are encapsulated into Zr-based MOF (UiO-66), which combines the advantages with high power conversion efficiency of QDs and the high surface area and porosity of UiO-66. In addition, benefiting from the close contact between the Cs 3 Bi 2 Br 9 QDs and the UiO-66 enables the photogenerated electrons in the QDs to be rapidly transferred to the MOF. As a result, the Cs 3 Bi 2 Br 9 @UiO-66 composite exhibits a higher yield for photocatalytic CO 2 reduction than that of the prepared large-sized composite of Cs 3 Bi 2 Br 9 and UiO-66.
研究领域:
材料科学
·
环境科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2025
·
IF 3.9
Shanqiu Liu,Enze Yu,Taotao Ge,Qing Liu,Yu Zhong,Wei Cui,Jie Yu,Jingguo Li
Nanocellular polymer foams are highly valuble for their lightweight nature, high strength, and unique nanostructures, which offer significant potential across a variety of applications. However, their production and practical use are limited by low cell nucleation efficiency and the requirement for extremely high-pressure foaming processes. In this study, we successfully fabricated poly(methyl methacrylate) (PMMA) nanocellular foams with a cell density on the order of 1012 cells cm–3 at a relatively low foaming pressure of 6.0 MPa. This achievement was made possible through the use of defective UiO-66 nanoparticles as nucleation enhancers, which demonstrated a high nucleation efficiency of 1.11. We synthesized four types of defective UiO-66 nanoparticles, each with varying levels of defects, and confirmed their efficacy as nucleators for PMMA nanofoams. The successful synthesis of these defective UiO-66 nanoparticles was verified using Fourier Transform Infrared Spectroscopy, X-ray Diffraction, Scanning Electron Microscopy (SEM), and Energy Dispersive X-ray Spectroscopy. The cell size and density of the PMMA nanocellular foams were characterized via SEM analysis. Our findings showed that the incorporation of defective UiO-66 nanoparticles markedly reduced the cell size of the PMMA foam, achieving a higher cell density. This improvement is attributed to a decrease in the free energy required for cell nucleation within nanocavities located at the matrix–nucleator interface. Consequently, the careful design of high-performance nucleating particles and the judicious choice of foam matrix components emerge as critical strategies in developing polymer cellular materials with nanoscale cell dimensions. These insights significantly advance the fabrication of polymer foams with enhanced thermal insulation properties and have broad implications for the field of cellular materials science. By optimizing nucleation mechanisms and material combinations, this work opens new avenues for the development of advanced cellular polymers tailored for applications requiring superior insulation or lightweight yet robust structures.
研究领域:
材料科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Nano Materials
·
2025
·
IF 5.5
Feng Ding,Xiong Shuai,Yanyan Chen,Donglan Zhang,Fangwei Qi,Cijun Shuai
Following peripheral nerve injury, a large number of macrophages will be recruited to the nerve defect site to regulate the immune microenvironment and then initiate a series of inflammatory reactions, which is not conducive to nerve repair. Electrical stimulation can not only affect the polarity of macrophages by regulating the immune microenvironment but also promote nerve regeneration by modulating voltage-gated ion channels. However, traditional electrical stimulation relies on power sources, wires, and implanted electrodes, which may pose risks of infection and secondary surgery. Here piezoelectric materials Ti3C2Tx/UiO-66 are synthesized by a hydrothermal method and then blended into PLLA to prepare a self-power nerve scaffold using laser additive manufacturing technology. Under ultrasound stimulation, UiO-66 nanoparticles can generate localized piezoelectric potential, while Ti3C2Tx nanosheets accelerate the charge transfer. The results indicate that a nerve scaffold promotes the current generation, with a current of up to 0.036 μA. The results indicate that electrical stimulation can promote the transformation of macrophages into the M2 antiinflammatory phenotype by inhibiting the Ca2+-CaMKII-NF-κB signaling pathway. Furthermore, the scaffold can upregulate the expression of bone marrow mesenchymal stem cell neural markers Tuj and Map under ultrasound treatment. This work provides insights into wireless electrical stimulation regulating the immune microenvironment to promote nerve repair.
研究领域:
生物医学工程
·
材料科学
·
神经科学
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Pu Zhou,Han Dong,Wanglin Zhang,Jiachen Liu,Yefei Tian,Yi Li,Jiabei Luo,Song Xiao,Kerui Li,Hongye Yuan
Developing metal–organic framework (MOF)-based sorbents with high water-uptake capacity and mild regeneration conditions remains challenging, but is highly sought after for addressing water shortages. Herein, we report a strategy for fabricating thermal-responsive Poly (N-isopropylacrylamide) (PNIPAM)/UiO-66 composite aerogels with variable PNIPAM loading by leveraging the ordered nanopores of UiO-66 colloids, enabling the confined polymerization of NIPAM monomers within the pores, which allows for controllable water capture and release at above 32 ℃. The thermal-responsive PNIPAM/UiO-66 composite aerogels, with varying PNIPAM loadings, demonstrated an outstanding maxima water capture of over 2100 wt% at room temperature and reversible release at above 32 ℃. This performance sets a new benchmark for the leading water-capture adsorbents reported in the literature, thanks to the extensive specific surface area of the aerogels and the unique hydrophilicity-hydrophobicity transition exhibited by the PNIPAM component. More intriguingly, the aforementioned phase transition can be directly visualized by incorporating 4-(1,2,2-triphenylvinyl) benzoic acid (TPE-COOH) molecules with the well-known aggregation-induced emission (AIE) effect into the aerogels. The remarkable water-uptake ability and mild release conditions showcased in this study open new possibilities for practical water harvesting.
研究领域:
材料科学
·
环境科学
·
化学工程
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2024
·
IF 1.5
Guo Dingge,Xiao Jing,Ning Yang,Yu Hongchao,Jin Tianxiang,Huang Bin,Qian Yong
The efficient removal of thorium from the environment is critical due to the risks it poses to organisms. Metal–organic frameworks are favored by scholars because of their potential to effectively adsorb a variety of heavy metal ions in wastewater treatment. In this work, the interaction of UiO-66-NH 2 surface with graphene, enhances adsorption capacity of MOFs. Optimal adsorption conditions have been identified, and a detailed adsorption mechanism has also been comprehensively discussed. The theoretical maximum adsorption capacity exhibited by UiO-66-GO is 119.57 mg g −1 . Moreover, it shows a fast adsorption rate and reached equilibrium within 20 min. The development of materials with good adsorption performance and fast adsorption for Th(IV) plays an important role in the development of Th(IV) adsorption in the future.
研究领域:
环境科学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2025
·
IF 9.7
Xiangrong Li,Shaohua Xie,Dongman Hou,Wenliang Wang,Guoqiang Li
Indium nitride (InN) exhibited significant potential as a photoelectrode material for photoelectrochemical (PEC) water splitting, attributed to its superior light absorption, high electron mobility, and direct bandgap. However, its practical application was constrained by rapid carrier recombination occurring within the bulk and at the surface. To address these limitations, researchers developed InN/UiO-66 heterojunction photoelectrodes, which markedly enhanced PEC water splitting for hydrogen production. Functionalization of the UiO-66 metal–organic framework (MOF) with hydroxyl (–OH) groups optimized the bandgap and improved light absorption, facilitating efficient charge separation and transfer processes. The functionalization also mitigated surface defect states in the InN nanorods (NRs), which were a major source of photogenerated carrier recombination, thereby enhancing overall photocatalytic activity. Compared to pristine InN NRs, the optimized InN/UiO-66-(OH) 2 electrode achieved a photocurrent density of −0.42 mA cm −2 and an applied bias photon-to-current efficiency (ABPE) of 0.47 % at −0.5 V vs. reversible hydrogen electrode (RHE). Furthermore, the InN/Ag/UiO-66-(OH) 2 system demonstrated a hydrogen production rate of 1.82 μmol min −1 under AM 1.5G illumination, with excellent long-term stability. This study provided critical insights into the design of efficient and durable PEC photoelectrodes, achieved the highest hydrogen yield reported for indium-based photocathodes to date, and underscored the promise of InN-based materials for solar-driven hydrogen production in the context of clean energy applications.
研究领域:
材料科学
·
能源科学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）