Nanoscale
·
2025
·Vol. 17
·期 39
·23010-23021
·
IF 5.1
Binqi He,Yunping Ma,Xinyue Xiang,Sifan Sun,Qianzuo Liu,Ting Zhang,Maiyong Zhu,Tie Li
The development of high-performance electrochemical catalysts capable of ultrasensitive detection of small molecules remains a significant challenge. Emerging two-dimensional materials, particularly metallenes such as Pd metallene, have demonstrated considerable potential in addressing these challenges. However, several critical limitations remain, including the need for further enhancement of electrochemical activity, detection sensitivity, and molecular selectivity. In this study, a one-step hydrothermal approach was employed to synthesize porous PdPr bimetallene alloys with a semi-transparent, wrinkled architecture, which function as high-performance catalysts in flexible electrochemical sensors. These materials exhibit excellent sensitivity and selectivity toward ethylene glycol detection. The incorporation of Pr not only induces unique synergistic lattice distortion effects but also enhances the thermodynamic stability of defect sites, which act as efficient electron-transfer channels and significantly activate the catalytic centers. This structural engineering significantly improves both electronic conductivity and structural stability, while also accelerating electron-transfer kinetics and enhancing the activity of the ethylene glycol oxidation reaction (EOR). This work not only demonstrates the effectiveness of active-site engineering in PdPr bimetallene for improved catalytic performance but also broadens the application of metallenes in the sensing of small molecules, aligning with current trends in advanced sensing technologies.
研究领域:
材料科学
·
电化学
·
纳米技术
·
传感器与探测器
·
催化
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DOI
PubMed
高影响因子
Biomaterials Science
·
2019
·Vol. 7
·期 6
·2520-2532
·
IF 5.251
Xu-Qi Kang,Yue Qiao,Xiao-Yang Lu,Sai-Ping Jiang,Wei-Shuo Li,Xiao-Juan Wang,Xiao-Ling Xu,Jing Qi,Yong-Hong Xiao,Yong-Zhong Du
Multiple drug resistance and the increase in the appearance of superbugs together with the exceedingly scant development of new potent antibiotic drugs pose an urgent global medical threat and imminent public security crisis. In the present study, we fabricated well-dispersed tocopherol polyethylene glycol succinate (TPGS)-capped silver nanoparticles (AgNPs) of about 10 nm in size. The hollow structure of the TPGS-capped AgNPs (TPGS/AgNPs) was confirmed and applied to load antibiotics. The TPGS/AgNPs proved to be able to cross the bacterial cell wall and penetrate into bacteria, thereby delivering more of the antibiotic to the interior of bacteria and thus enhancing the in vitro antibacterial effect of the antibiotic, even overcoming the drug-resistance in drug-resistant E. coli and Acinetobacter baumannii. It was found that the TPGS modification in the TPGS/AgNPs could decrease the activity of the efflux pumps AdeABC and AdeIJK in drug-resistant Acinetobacter baumannii via inhibiting the efflux pump genes adeB and adeJ, thus increasing the accumulation of the delivered antibiotic and overcoming the drug-resistance. Tigecycline delivered by TPGS/AgNPs could effectively antagonize drug-resistance in an acute peritonitis model mice, thereby increasing the survival rate and alleviating the inflammatory response. TPGS/AgNPs were developed as a novel and effective antibiotic delivery system and TPGS was demonstrated to have great potential as a pharmaceutical excipient for use in drug-resistant infection therapy.
研究领域:
药剂学
·
纳米技术
·
微生物学
·
传染病学
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DOI
PubMed
高影响因子
JOURNAL OF SURFACTANTS AND DETERGENTS
·
2014
·Vol. 17
·期 6
·1089-1097
·
IF 1.352
Guo Shengnan,Sun Xiaowen,Zou Qichao,Zhang Jinzhi,Ni Hong
A series of cationic gemini surfactants containing two dimethylalkylammonium chains linked by ethylene glycol bisacetyl spacers were synthesized [G
m -A n A- m
, G = gemini surfactant, m = 12 (–C 12 H 25 ), 14 (–C 14 H 29 ), or 16 (–C 16 H 33 ), A = acetyl, and n = 2, 3, or 4 is the number of ethylene glycol units in the spacers]. Because of the inductive effect of the oxygen atom in the spacer, acylation can take place using chloroacetyl chloride instead of bromoacetyl bromide which helps to limit the use of environmentally harmful reagents. Critical micelle concentrations were determined using conductivity measurements. The antibacterial activities of the surfactants against Gram-positive bacterium Staphylococcus aureus and Gram-negative bacterium Escherichia coli were evaluated from the minimum inhibitory concentration (MIC), minimum bacterial concentration, a time–kill study, and the inhibitory zone. Increasing the length of the spacer did not result in an obvious change of antibacterial activity. However, increasing the length of the alkyl chain apparently increased the antibacterial activity against S. aureus but decreased the antibacterial activity against E. coli . The G 12-A2A-12 surfactant had the lowest CMC of 1.26 mmol L −1 and exhibited the best antibacterial activity with a MIC of 32 μg mL −1 toward S. aureus and 64 μg mL −1 toward E. coli in the presence of 10 5 CFU of bacteria. This work indicated that these cationic gemini surfactants have potential applications as antibacterial agents and emulsifiers.
研究领域:
化学
·
微生物学
·
药学
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DOI
高影响因子
JOURNAL OF APPLIED POLYMER SCIENCE
·
2012
·Vol. 128
·期 1
·89-96
·
IF 1.289
Qunfang Wang,Li Ren,Caixia Xu,Zhichen Zhai,Jia-an Zhou,Yongchang Yao,Huan Xia,Yingjun Wang
This study presented the synthesis and characterization of glucosamine (GlcN) modified poly (ethylene glycol) (PEG) hydrogels. The chemical structure was characterized by Fourier transform infrared (FTIR) and proton nuclear magnetic resonance ( 1 H NMR) spectroscopy. The morphology of hydrogels was observed by scanning electron microscopy (SEM). The results indicated that GlcN was successfully incorporated into PEG hydrogel network. Moreover, the data of the swelling ratio showed that the ratio of GlcN-modified PEG hydrogels was lower than that of pure poly(ethylene glycol) diacrylated (PEGDA). Biocompatibility of unreacted GlcN monomer and GlcN-modified hydrogels was also evaluated in vitro . Compared with glucosamine hydrochloride, 2 and 5 m M N -acroloyl-glucosamine monomer exhibited no toxicity against bone marrow stromal cells (BMSCs), while with the concentration increased to 10 m M , cell viability appeared to decrease. However, when BMSCs were encapsulated in GlcN-modified hydrogels via photopolymerization method, cells remained vigorous viability. Metabolic activity of the encapsulated cells demonstrated GlcN-modified hydrogels was favorable for cell proliferation. Compared with free GlcN, covalent binding GlcN showed lower cytotoxicity and higher cell proliferation properties. As a result, GlcN-modified PEGDA hydrogels could be used as safe and injectable cell carriers for in situ tissue engineering applications. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
研究领域:
生物材料
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组织工程
·
医学
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DOI
高影响因子
AICHE JOURNAL
·
2026
·
IF 4
Bo Wang,Tan Li,Xuhao Xie,Wenbo Zhao,Zhiyong Xu,Yongming Luo
The efficient removal of hydrogen sulfide (H 2 S) is crucial for clean energy and environmental protection, with amine-based absorption being the mainstream due to its cost-effectiveness and high efficiency. This work designed eight hybrid absorbents using organic diamines and ethylene glycol (EG). Absorption capacity measurements revealed that at 303.15 K and 1 bar, short-chain diamines exhibited ~1 mol/mol, while long-chain ones reached ~2 mol/mol. Notably, the 1,4-butanediamine-EG reached a remarkable capacity of 1.7 mol/mol at 0.2 bar, and the N , N , N ′, N ′-tetramethyl-1,6-hexanediamine-EG reached 2.06 mol/mol at 1 bar. Absorption capacity positively correlated with diamine chain length, and primary/secondary amines outperformed tertiary amines at low partial pressures. A reaction equilibrium thermodynamic model was established to verify the structure–capacity relationship via parameters like equilibrium constant K . The selectivity of H 2 S/CO 2 was studied. This provides theoretical guidance for H 2 S absorbent design and industrial applications.
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高影响因子
Journal of the Iranian Chemical Society
·
2022
·Vol. 19
·期 12
·4637-4644
·
IF 2.271
Su Kai,Liu Mao,Xu Meisong,Zhao Tianxiang
Ether-rich tetraethylene glycol is an alternative SO 2 absorbent due to the good solubility and high stability. Due to the high viscosity of tetraethylene glycol, it is usually necessary to add an appropriate amount of water to reduce the viscosity. In this case, insight into the interaction mechanism between molecules can guide the most reasonable amount of water to be added to tetraethylene glycol in the actual SO 2 gas separation process. In this work, the structure–activity relationship of SO 2 in tetraethylene glycol and its aqueous solution was studied by measuring the SO 2 solubility and spectral features. Using an isochoric saturation method, the solubility of SO 2 in tetraethylene glycol (1) + water (2) mixtures was determined at 303.2 K and pressures up to 120 kPa. It was found that the solubility of SO 2 increases gradually with increasing mass fraction of tetraethylene glycol and the dissolution process of SO 2 conforms to Henry’s law within the current experimental conditions. The Henry’s constants were further calculated based on solubility data. Furthermore, FTIR, UV–Vis, and 1 H NMR spectroscopic characteristic for dissolved SO 2 into tetraethylene glycol (1) + water (2) mixture was also investigated, revealing significant information about the SO 2 absorption mechanism.
研究领域:
化学工程
·
环境科学
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DOI
高影响因子
JOURNAL OF FORESTRY RESEARCH
·
2020
·Vol. 32
·期 4
·1779-1787
·
IF 1.689
Cai Hangchuan,Wang Zhiqi,Xie Di,Zhao Panpan,Sun Jianping,Qin Daoyu,Cheng Fangchao
Transparent wood has potential application in intelligent building, solar cell, electronics, and other advanced materials, while its single functionability hinders its further development. Flexible transparent wood (FTW) was prepared by alkaline pretreatment and bleaching treatment of paulownia wood followed by impregnation of epoxy resin and ethylene glycol diglycidyl ether (EDGE). The effect of delignification degree on the optical and mechanical properties of FTW was studied, and the influence of the epoxy/EDGE ratio on the flexibility and mechanical properties of FTW was also investigated. The results showed that higher delignification degree resulted in higher transmittance of FTW. More EDGE addition led to better flexibility of FTW, while overmuch addition of EDGE will reduce the mechanical properties. The optimal FTW sample resulted in a high transmittance of 89% and an ultrahigh haze value of 97% with outstanding flexibility and excellent mechanical properties. The investigation of FTW broadens the research field of transparent wood, and provides great possibility for its application in flexible wearable devices and flexible materials.
研究领域:
材料科学
·
林业工程
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DOI
高影响因子
REACTIVE & FUNCTIONAL POLYMERS
·
2017
·
IF 3.151
Kewen Li,Chao Zhou,Shunli Liu,Fang Yao,Guodong Fu,Liqun Xu
Hydrogels have been considered as promising materials in tissue engineering and biomedical areas. However, the weak and brittle nature of common synthetic hydrogels largely hinders their potential applications. Therefore, it is challenging to fabricate tough hydrogels for biomedical applications . In this manuscript, well-defined and thermo-responsive polyurethane-poly(ethylene glycol) (PU-PEG) hydrogels were prepared via thermally-induced copper-catalyzed 1,3-dipolar azide-alkyne cycloaddition (CuAAC) using azido-pendent PU-PEG and dialkynyl PEG as the gel precursors. The physical properties of the as-formed hydrogels were investigated by swelling ratios and mechanical tests. The PU-PEG hydrogels not only possess thermo-responsive and excellent mechanical properties, but also exhibit good biocompatibility .
研究领域:
生物医学工程
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材料科学
·
组织工程
·
高分子化学
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DOI
高影响因子
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
·
2022
·Vol. 101
·期 7
·4217-4229
·
IF 2.5
Jia Wang,Rongchun Shen,Yueqiang Cao,Wei Li,Jinghong Zhou
1,2-butanediol (1,2-BDO) and 1,2-propanediol (1,2-PDO) are inevitably side produced in the ethylene glycol (EG) production processes from non-petroleum routes, but are very difficult to separate by the ordinary distillation method because of the closeness of their boiling temperatures to EG, thus compromise the economy of these processes. The azeotropic distillation process using 1-octanol (CPO) as an entrainer to separate EG and 1,2-BDO mixture with or without 1,2-PDO was studied in this paper. Four binary vapour–liquid equilibrium data of EG-1,2-BDO, EG-CPO, 1,2-BDO-CPO, and 1,2-PDO-CPO were measured using an Ellis equilibrium kettle and regressed with the thermodynamic model of non-random two liquid to obtain the corresponding binary interaction parameters. On this basis, azeotropic distillations with CPO as an entrainer were designed to separate EG and 1,2-BDO with or without 1,2-PDO. The complete separation processes, including the azeotropic distillation and CPO recovery process consisting of extraction with H 2 O and subsequent distillation, were simulated and optimized with Aspen Plus for both the EG-1,2-BDO binary mixture and the EG-1,2-BDO-1,2-PDO ternary mixture. The simulation results show that the azeotropic distillation method with CPO as an entrainer can effectively separate the mixture of EG-1,2-BDO and EG-1,2-BDO-1,2-PDO, achieving EG of 99.90% purity with 99.98% recovery and 1,2-BDO of 99.30% purity with 99.45% recovery for the binary mixture, and achieving EG of 99.90% purity with 99.80% recovery, 1,2-BDO of 99.35% purity with 99.35% recovery, and 1,2-PDO of 90.59% purity with 94.38% recovery for the ternary mixture. These processes are promising for industrial application and can significantly improve the economy of non-petroleum EG production.
研究领域:
化学工程
·
分离技术
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Kaiqi Du,Guangpeng Chen,Hao Pan,Liting Fan,Huiping Xu,Wenqiu Su,Shaolong Wan,Wenjing Hong
Base-catalyzed transesterification was studied for PGMEA synthesis avoiding acid and water. • EtONa was identified as the catalyst and its deactivation mechanism was EA Claisen condensation. • In situ formation of sodium PGME can partially suppress catalyst deactivation at low loadings. • 99.90% PGMEA with negligible metal and moisture was achieved by customized rectification. • Process simulation of two-stage distillation shows that electronic-grade PGMEA is achievable. Propylene glycol methyl ether acetate (PGMEA) is an essential electronic-grade solvent in semiconductor manufacturing. However, the conventional esterification route introduces acid and water, requiring extensive purification to meet ultra-stringent quality standards. Herein, an alternative transesterification process with base catalysts that inherently avoids acid and water formation was systematically investigated. Sodium ethoxide (EtONa) exhibited the highest catalytic activity among the bases examined. Catalyst deactivation was traced to EtONa-catalyzed Claisen condensation of ethyl acetate (EA), while the formation of sodium PGME (PGMENa) partially suppressed this effect at low catalyst loadings. Using a customized rectification process, PGMEA with 99.90% purity and negligible metal content was obtained, and process simulation results indicate that electronic-grade purity (99.9999%) is achievable. This work demonstrates a practical and industrially viable route for the production of ultra-high-purity PGMEA.
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DOI
高影响因子
Energy Material Advances
·
2026
·
IF 17.4
Huan Ge,Yi Ma,Ning Jian,Lin Wang,Yaoyue Yang,Jing Yu,Jordi Arbiol,Haiting Wang,Jiaming Ding,Luming Li,Andreu Cabot,Junshan Li
Electrocatalytic ethylene glycol oxidation (EGOR) is central to energy conversion andpolyethylene terephthalate (PET) plastics upcycling, yet its deployment is limited by thescarcity of selective, durable anodes. We report cobalt nickel diselenide (Co1-xNixSe2)nanoparticles (NPs) prepared by hydrothermal synthesis, where Ni incorporationmodulates the spin states of Co and tailors the electronic structure. In situ Fouriertransform infrared spectroscopy identifies glycolaldehyde and glyoxylic acid as keyintermediates, revealing a Ni-induced shift toward a C–C bond-cleavage pathway. Anequimolar Ni/Co composition delivers ≈90% Faradaic efficiency (FE) to formate at 1.6 Vversus RHE while sustaining ~100 mA cm-2 over 10 h testing. The enhanced activity andselectivity arise from spin-state optimization, which strengthens adsorption of reactionintermediates, promotes selective dehydrogenation and controlled C–C scission, andsuppresses over-oxidation. These results establish spin-state engineering as an effectivelever to steer the electrooxidation pathways of small organic molecules and guide thedesign of high-performance anode catalysts.
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DOI
高影响因子
Journal of Energy Storage
·
2026
·
IF 10.7
Zijiao Guo,Fankai Lin,Qianchao Ma,Mengyao Yang,Xianjie Liu,Mingyong Liu,Yue'na Jiang,Xin Min,Zhaohui Huang
To address the high cost, low thermal conductivity, and limited solar-thermal conversion efficiency of conventional composite phase change materials, this study develops a wood-derived composite phase change material based on polyethylene glycol and a wood-derived porous carbon skeleton. Wood chips and phenolic resin were used as carbon sources to fabricate an integrated porous carbon framework through dry pressing and carbonization, and polyethylene glycol was subsequently incorporated as the phase change component. The phenolic resin promoted the formation of a continuous and mechanically stable carbon skeleton, resulting in a thermal conductivity of 0.57 W/(m·K), approximately three times that of pure polyethylene glycol, and a compressive strength of 0.85 MPa. As a further enhancement, silicon carbide nanowires were generated in situ by introducing silicon powder into the carbon skeleton. The nanowires improved heat-transfer pathways and regulated the pore structure, increasing the thermal conductivity to 1.13 W/(m·K) while enabling a polyethylene glycol loading of 62%. The resulting composite exhibited good shape stability during phase transition, which were attributed to the capillary confinement and interfacial interactions provided by the porous carbon framework. In addition, the combined effects of the biomass-derived carbon skeleton and silicon carbide nanowires contributed to a solar–thermal conversion efficiency of 78.7%. These results demonstrate that wood-derived porous carbon can serve as a low-cost and effective supporting framework for polyethylene glycol, while the in-situ-formed silicon carbide nanowires provide an additional route for improving heat transfer and solar–thermal conversion. This study offers a practical strategy for developing biomass-based composite phase change materials with favorable thermal storage, mechanical, and solar-thermal conversion performance.
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高影响因子
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