CERAMICS INTERNATIONAL
·
2023
·
IF 5.2
Lei Yu,Kuibao Zhang,Kui Liu,Baozhu Luo
In this study, the chemical durability of Gd 2 Zr 2 O 7 transparent ceramics was investigated under different pH environments. The influence of acidic and alkaline environments on the leaching behavior of Gd 2 Zr 2 O 7 immobilization matrix were studied to simulate the disposal of nuclear waste forms in deep geological landfills. The measured results demonstrate that the normalized leaching rates in acidic environments are higher than those in alkaline and neutral environments. The macroscopic color of all samples fades after leaching, and the visible range in-line transmittance of the leached transparent ceramics decreases slightly at pH ≤ 9. The leaching behavior leads decrement of lattice volume and increment of surface roughness, but it exhibits no significant effect on the surface elemental distribution. Never the less, Gd 2 Zr 2 O 7 transparent ceramic exhibits excellent chemical durability in weak alkaline environment, and the leaching process leads to the discoloration of Gd 2 Zr 2 O 7 transparency.
研究领域:
材料科学
·
环境科学
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DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2018
·
IF 4.439
Feng Chen,Yazhi Zhu,Wei Li,Jintao Yang,Ping Fan,Zhengdong Fei,Mingqiang Zhong,Lingqian Chang,Tairong Kuang
Surfaces with stimuli-responsive properties have shown prominent applications in bioengineering, controlled drug release and biosensors in recent years. In this work, we report a surface-initiated reversible addition–fragmentation chain transfer polymerization method to graft azobenzene-containing diblock copolymer (azo-BCP) brushes onto an Indium Tin Oxide (ITO) glass surface. In this method, a sequential azo block serves as the outer layer that controls the closure or opening of the brushes, and the second block (PDMAEMA) acts as the inner layer that switches between swollen and collapsed chain states in response to different pH values and temperatures. Upon exposure to UV light, the ITO surface became more hydrophilic (>10° change of contact angles), and its friction coefficient (0.5–0.9) increased; this suggests a loose aggregation of the azo block. Additionally, the ion conductivity of the ITO surface can be influenced by the aggregation state of the azo-BCP brushes, thus leading to the transportation of light-triggered ions under various pH values and temperatures. This work provides a deep understanding of the surface properties of a sensitive hybrid material upon various stimuli for electrode purpose, thereby paving the way for the development of bioengineering and environmental sensory applications.
研究领域:
生物工程
·
材料科学
·
传感器技术
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产品关联
DOI
高影响因子
Materials Science & Engineering C-Materials for Biological Applications
·
2016
·
IF 3.42
Minming Wu,Zhaoyu Cao,Yunfei Zhao,Rong Zeng,Mei Tu,Jianhao Zhao
Novel pH-responsive biodegradable biomimetic nanocarriers were prepared by the self-assembly of N -acetyl- l -histidine-phosphorylcholine-chitosan conjugate (NAcHis-PCCs), which was synthesized via Atherton-Todd reaction to couple biomembrane-like phosphorylcholine (PC) groups, and N , N ′-carbonyldiimidazole (CDI) coupling reaction to link pH-responsive N -acetyl- l -histidine (NAcHis) moieties to chitosan. In vitro biological assay revealed that NAcHis-PCCs nanoparticles had excellent biocompatibility to avoid adverse biological response mainly owing to their biomimetic PC shell, and DLS results confirmed their pH-responsive behavior in acidic aqueous solution (pH ≤ 6.0). Quercetin (QUE), an anti-inflammatory, antioxidant and potential anti-tumor hydrophobic drug, was effectively loaded in NAcHis-PCCs nanocarriers and showed a pH-triggered release behavior with the enhanced QUE release at acidic pH 5.5 compared to neutral pH 7.4. The results indicated that pH-responsive biomimetic NAcHis-PCCs nanocarriers might have great potential for site-specific delivery to pathological acidic microenvironment avoiding unfavorable biological response.
研究领域:
药剂学
·
生物材料学
·
医学
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产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 84
·80964-80971
·
IF 3.289
Jingjing Yang,Shufen Zhang
This work describes the synthesis and pH sensitivity of polyampholytes containing aromatic rings which were prepared from a poly(acrylamide-co-vinylamine) oligomer and aryl sulfonate derivatives. The structures of the products were characterized by Fourier transform infrared spectroscopy, liquid chromatography-mass spectrometry and nuclear magnetic resonance spectroscopy analysis. The effects of degree of substitution, concentration of the polyampholyte solution, the amount of sulfonate groups in the aryl sulfonate derivatives, and the aromatic ring on the pH sensitivity of the polyampholytes were discussed in detail. The results exhibited that the pH sensitivity of these polyampholytes was mainly affected by the molar ratio of cationic to anionic groups in the polyampholytes which can be controlled by changing both the degree of substitution and the amount of sulfonate groups in the aryl sulfonate derivatives at the fixed degree of substitution.
研究领域:
高分子化学
·
材料科学
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产品关联
DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2023
·
IF 4.5
Zhuo Chen,Waqar Uddin,Gang Hu,Xiaofeng Shen,Jie Yang,Lin Hu,Zhaohui Fang
In this study, we report an electrochemical method for the identification of three halates (ClO 3 − , BrO 3 − , and IO 3 − ) by using a pH clock system composed of HCHO-NaHSO 3 -Na 2 SO 3 . When equal amounts of analytes (halates) are separately added to the clock system, the increase in the induction period for the clock system is observed to be IO 3 − > BrO 3 − > ClO 3 − . Three halates are then distinguished from each other by such different perturbation effects. Furthermore, there is a linear relationship between the concentration of halates and the induction period in the range of 5.0 × 10 −4 -2.0 × 10 −3 mol/L. The quantitative analysis for halates is then to be achieved. Finally, the perturbation mechanisms of the three halates on the pH clock system are explained in detail.
研究领域:
分析化学
·
环境科学
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产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2023
·
IF 7.7
Xingyu Lin,Yong Zhang,Ziteng Yang,Wenjian Yue,Ruoxin Zhang,Jie Qi,Hongsheng Lu
pH-regulated wettability transformation materials have gained increasing attention attributing to the capacity for sustainable oil-water separation. In this work, a smart quartz sand (OD-SiO 2 @sand) with controllable wettability was designed as a filter media for efficient oil-water mixtures and water in oil emulsions separation. The OD-SiO 2 @sand was synthesized by grafting nano-silica and modifying with two silane couplers, including N, N-Diethyl-3-(trimethoxysilyl)− 1-propanamine (DTP) and trimethoxy(octyl)silane (OTMS). OD-SiO 2 @sand featured superhydrophobicity with a water contact angle (WCA) of 151.6°, which suggests selective separation capacity for oil and high permeation flux up to 4018 L.m −2 ∙h −1 . Meanwhile, OD-SiO 2 @sand exhibits superhydrophobicity and hydrophilicity in neutral and acidic solutions resulting from the reversible protonation of grafted DTP, which was revealed by 1 H NMR and molecular dynamics simulations. OD-SiO 2 @sand posed controllable oil-water separation performance, which remains superhydrophobicity with a WCA of 150.4° after 10 cycles of filtration processes upon pH regulation. Furthermore, OD-SiO 2 @sand demonstrated efficient demulsification and separation capacity for various water in oil emulsions, achieving a purified oil size of less than 10 nm and a permeation flux up to 1850 L.m −2 ∙h −1 . Thus, OD-SiO 2 @sand shows promising applicability in the field of oil recovery and oil quality improvement.
研究领域:
材料科学
·
环境工程
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产品关联
DOI
高影响因子
JOURNAL OF MOLECULAR LIQUIDS
·
2024
·
IF 5.3
Bin Zhou,Xiaoqian Cao,Yujuan Rong,Can Wu,Yuying Hu,Bin Li,Bing Cui
Modifying and improving protein functionality is crucial for expanding the application of proteins in the food industry. The aim of this study was to investigate the effect of pH-shift treatments on the emulsifying and interfacial properties of glutenin (Glu). Glu was exposed to acidic (pH 1–3) and basic (pH 10–13) pH values for 4 h and subsequently neutralized for refolding. The pH-shifting treatments significantly improved Glu surface wettability with three-phase contact angle from 66.21 ± 2.31° to 91.4 ± 0.88°. The alkali shift treatment resulted in samples with larger K diff values. The treated samples also showed amplitude and frequency dependence in their E, E v , and E d values, with higher E and E d values indicating an elastic membrane at the interface. Emulsions prepared from Glu treated with alkali shift treatment exhibited smaller particle size, larger ζ-potential, and more stable storage properties. The rheological results indicated higher viscosity, thixotropy and creep of emulsions prepared from alkali shift treated Glu. In conclusion, treatment of Glu with alkali shift resulted in significant improvements in emulsifying and interfacial properties, suggesting that Glu may be a more promising ingredient for use in food.
研究领域:
食品科学
·
蛋白质化学
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产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2019
·
IF 3.973
Wen Yao Hu,Zhi Min Wu,Qian Qian Yang,Yue Jin Liu,Juan Li,Can Yang Zhang
The development of intelligent oral drug delivery carrier aiming at efficiently bring insulin to intestine is of great significance for diabetes mellitus therapy. In the present study, a series of amphiphilic pH-sensitive block copolymer poly(methyl methacrylate- co -methacrylicacid)- b -poly(2-amino ethyl methacrylate) [P(MMA- co -MAA)- b -PAEMA] was synthesized via activators regenerated by electron transfer atom transfer radical polymerization (ARGET ATRP) and further self-assembled into pH-responsive cationic polymeric micelles (PCPMs) for oral insulin delivery. The structure and molecular weight were confirmed by proton nuclear magnetic resonance ( 1 H-NMR), Fourier transforming infrared spectrum (FT-IR) and gel permeation chromatography (GPC), respectively. The critical micelle concentration (CMC) values of these copolymers were measured by fluorescent probe method at pH 1.2 (8–15 μg/mL) and pH 7.4 (22–42 μg/mL), respectively, demonstrating high stability at acidic environment. A decrease in the particle size of PCPMs was associated with an increased pH at beginning, which reached around 200 nm at neutral pH, while the particle size increased obviously with pH increase, indicating the pH-sensitivity of PCPMs. The insulin was entrapped into the core of PCPMs (Ins-loaded PCPMs) with high loading efficiency via diafiltration method. The in vitro experiments show Ins-loaded PCPMs have low toxicity and exhibit pH-triggered release profile with remitted initial burst release. The results indicate that the PCPMs self-assembled from P(MMA- co -MAA)- b -PAEMA may be potential carriers for efficient oral delivery of insulin with controlled release property.
研究领域:
药剂学
·
生物材料
·
糖尿病治疗
✓ 已验证
DOI
高影响因子
DYES AND PIGMENTS
·
2025
·
IF 4.2
Wenbin Zhu,Zemin Ma,Liwen Zhang,Chunbing Yang,Fujun Xu,Jiangyong Yu
Smart textiles with real-time visual monitoring abilities of environmental pH hold significant importance in wearable products. Natural dyes have gained growing interest as eco-friendly pH indicators, however, their stability and large-scale isolation remain challenging. In this work, we developed a type of pH-monitoring colorimetric indicator based on anthocyanins, a natural dye extracted from red cabbage, with enhanced affinity to cotton fiber substrates by utilizing metal salts and biopolymers. Compared to cotton fabric directly dyed with pristine anthocyanins, this colorimetric fabric demonstrates higher color contrast, superior reversibility of color change, and enhanced light and washing color fastness. The color strength (K/S) was significantly improved from 0.136 for untreated fabric to 1.266 for colorimetric fabric, and the excellent colorimetric properties maintained either after over 20 h washing or 12 h exposure to sunlight. This work addressed the issue of the easy light degradation of biomaterials, and provided a feasible optimization strategy for the development and application of environment-responsive biomass colorimetric textiles as smart and wearable products.
研究领域:
纺织科学
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生物材料学
·
环境科学
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产品关联
DOI
高影响因子
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
·
2024
·
IF 3.6
Mao-Lan Zhang,Gui-Ping Zhang,Hong-Shuo Ma,Yu-Zhu Pan,Xiao-Ling Liao
Considering the differences in pH between bacterial infection microenvironment and normal tissues, a series of pH-responsive drug-release amphiphilic polyurethane copolymers (DPU-g-PEG) have been prepared in this work. Fourier transform infrared (FT-IR) spectroscopy and 1H NMR was selected to detect the structure of the condensed polymers. The DPU-g-PEG amphiphilic copolymers could form stable micelles with a hydrophilic shell of polyethylene glycol (PEG) and a hydrophobic core of polylactic acid (PLA). We loaded a model drug called triclosan onto DPU-g-PEG micelles and studied how pH affects their particle size, Zeta potential, and drug release performance. The results revealed that when exposed to acidic conditions, the surface potential of DPU-g-PEG micelles changed, the micelles’ particle size increased, and the drug release performance was significantly enhanced. These results suggested that the micelles prepared in this study can release more antibacterial substances at sites of bacterial infection. Meanwhile, we also investigated the impact of different ratios of soft and hard segments on the properties of micelles, and the results showed that the pH responsiveness of micelles was strongest when the ratio of soft segments (PLLA diol + PEG 2000): 1,6-hexamethylene diisocyanate (HDI): 2,6-Bis-(2-hydroxy-ethyl)-pyrrolo[3,4-f]isoindole-1,3,5,7-tetraone (DMA) = 1: 1.2: 0.2. Furthermore, the results of inhibition zone test, minimum inhibitory concentration (MIC), and minimum bactericidal concentration (MBC) all confirmed the antibacterial activity of triclosan-load DPU-g-PEG micelles. In conclusion, the DPU-g-PEG micelles produced in this study have the potential to be used as intelligent drug delivery systems in the biomedical field.
研究领域:
生物材料学
·
药剂学
·
微生物学
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产品关联
DOI
PubMed
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2015
·
IF 2.752
Jiao Wang,Xiao Chen,Wanling Cui,Sijing Yi
pH-responsive vesicles have been prepared from the mixture of 1-(10-(4-formyl-phenoxy) decyl)-pyridinium (FDP) or 1-methyl-3-(10-(4-formyl-phenoxy) decyl) imidazolium (FDI) with 1-octyl amine at a molar ratio of 1:1 in alkaline aqueous solutions. Their structures and morphologies were characterized by transmission electron microscopy with sample preparations by negative staining or freeze-fracture. Basically, the spherical unilamellar vesicles were formed with the mean diameters respectively of about 71 and 107 nm for two supra-amphiphile systems, which were based on the formation of dynamic imine bonds between amine and FDP (i-FDP) or FDI (i-FDI). The loading and release studies of a fluorophore, Nile red (NR), demonstrated the capabilities of these vesicles to encapsulate NR and a rapid release at low pH environment. The vesicles from i-FDP behaved relatively more sensitive to acidic environment than those from i-FDI. The dynamic transitions of supra-amphiphiles were characterized by nuclear magnetic resonance or fluorescence emission spectroscopy measurements. A lower critical micelle concentration and a higher aldehyde conversion efficiency of i-FDI than those of i-FDP were observed. The characteristics of facile formation, fast dissociation, and switchable morphologies of studied systems should be referable for designing novel smart supra-amphiphile systems with potential applications as controlled drug delivery systems.
研究领域:
生物化学
·
材料科学
·
药物递送
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产品关联
DOI
高影响因子
SENSORS
·
2018
·Vol. 18
·期 10
·3195
·
IF 2.475
Jianxin Zhang,Lei Zhou
Making use of the sol-gel technique, an optical pH sensor was prepared, which was made from an organic carrier with four indictors including congo red, bromophenol blue, cresol red, and chlorophenol red, cross-linked by tetraethyl orthosilicate (TEOS) and cellulose acetate. The actual detection range of the optical pH sensor is 2.5–11.0. The optimal ratio of ethyl orthosilicate, absolute ethanol, deionized water, and hydrochloric acid in glue precursor of the sensor-sensitive membrane was explored. The orthogonal experiment was designed to optimize the dosage of cellulose acetate,N,N-dimethylformamide (DMF), indicator, hydrochloric acid, and precursor glue in preparing the sensor-sensitive membrane. The linearity, measurement accuracy, repeatability, stability, and response time of the prepared pH sensor were tested. The measurement results were analyzed using a support vector machine and linear regression. The experimental results show that the optical pH sensor has a measurement accuracy of up to 0.2 pH and better stability and repeatability than the traditional pH glass electrode.Keywords:sol-gel technique;optical pH sensor;indicator;sensor-sensitive membrane
研究领域:
材料科学
·
化学传感器
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）