CHINESE JOURNAL OF POLYMER SCIENCE
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2022
·Vol. 40
·期 7
·789-798
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IF 3.815
Tian Xiu-Zhi,Yang Rui,Ma Jia-Jia,Ni Yong-Hao,Deng Hai-Bo,Dai Lei,Tan Jiao-Jun,Zhang Mei-Yun,Jiang Xue
Antistatic and strength properties are of vital importance for polyurethane rubber used in moving parts of many industrial instruments. Herein, polyurethane was composited with polyaniline and nanosilica based on in situ synthesis of polymer and physical mixing of these fillers to reach desired antistatic and mechanical properties. Chemical, morphological and thermal properties of the polyurethane/polyaniline/nanosilica composites were studied. The electrical resistivity of the composite decreased from 1.1×10 6 MΩ to 7.6×10 4 MΩ as a result of the addition of 4% polyaniline. The tensile strength and elongation at break of the polyurethane composites improved by nearly 300% and 100%, respectively, when compared with those of the neat polyurethane. The electronic resistance of PU/PANI/NS ternary is low enough for its antistatic property and decreases with the increase of the added nanosilica, which is unexpectedly and rather significant. Our results would shed light on the development of antistatic PU with excellent mechanical performance.
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JOURNAL OF POLYMER RESEARCH
·
2022
·Vol. 29
·期 6
·1-11
·
IF 3.061
Huang Tuankang,Qin Youlin,Li Mingchao,Gao Shanjun,Shen Chunhui
Deacetylated konjac glucomannan (DKGM)/calcium pectin (Ca-PEC) composite films were prepared by calcium hydroxide to realize deacetylation of konjac glucomannan (KGM) and the crosslinking of pectin at the same time. Fourier transform infrared spectroscopy (FTIR) indicates that there are intermolecular hydrogen bond and crosslinking structure between DKGM and Ca-PEC. The physical properties of the composite films are characterized by mechanical properties, water vapor permeability (WVP), swelling degree (SD), water solubility (WS), thermogravimetry (TG) and Opacity. The results exhibit that deacetylation of KGM and crosslinking structure of pectin reduce the swelling degree and water solubility of the films, as well as improve its thermal stability and tensile strength. These are attributed to enhanced intermolecular interactions, more compact entanglement of molecular chains and more solid spatial network structures. When pectin content is 40%, the combination property of DKGM / Ca-PEC composite film is the best.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2022
·Vol. 20
·期 1
·1-20
·
IF 9.429
Xie Qi,Li Shichao,Feng Xingxing,Shi Jingyu,Li Yang,Yuan Guanjie,Yang Conglian,Shen Yaqi,Kong Li,Zhang Zhiping
Background Conventional chemotherapy has poor efficacy in triple-negative breast cancer (TNBC) which is highly heterogeneous and aggressive. Imaging-guided therapy is usually combined with diverse treatment modalities, could realize the integration of diagnosis and treatments. Therefore, the primary challenge for combinational therapy is designing proper delivery systems to accomplish multiple synergistic effects. Results Herein, a facile nanoplatform was manufactured to fulfill the all-in-one approaches for TNBC combinational therapy. Fe 3+ -based metal-phenolic networks (MPNs) with bovine serum albumin (BSA) modification served as drug delivery carriers to encapsulate bleomycin (BLM), forming BFE@BSA NPs. The self-assembly mechanism, pH-responsive drug release behavior, and other physicochemical properties of this system were characterized. The potential of BFE@BSA NPs as photothermal transduction agents and magnetic resonance imaging (MRI) contrast agents was explored. The synergistic anti-tumor effects consisting of BLM-induced chemotherapy, Fenton reactions-mediated chemodynamic therapy, and photothermal therapy-induced apoptosis were studied both in vitro and in vivo. Once internalized into tumor cells, released BLM could cause DNA damage, while Fenton reactions were initiated to produce highly toxic •OH. Upon laser irradiation, BFE@BSA NPs could convert light into heat to achieve synergistic effects. After intravenous administration, BFE@BSA NPs exhibited great therapeutic effects in 4T1 tumor xenograft model. Moreover, as T 1 -weighted MRI contrast agents, BFE@BSA NPs could provide diagnosis and treatment monitoring for individualized precise therapy. Conclusions A nano-system that integrated imaging and combinational therapy (chemotherapy, chemodynamic therapy and photothermal therapy) were developed to kill the tumor and monitor therapeutic efficacy. This strategy provided an all-in-one theranostic nanoplatform for MRI-guided combinational therapy against TNBC. Graphical Abstract
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Nature Communications
·
2022
·Vol. 13
·期 1
·1-12
·
IF 17.694
Zhu Tianwen,Yang Tianjia,Zhang Qiang,Yuan Wang Zhang
Pure organic room temperature phosphorescence (RTP) materials become increasingly important in advanced optoelectronic and bioelectronic applications. Current phosphors based on small aromatic molecules show emission characteristics generally limited to short wavelengths. It remains an enormous challenge to achieve red and near-infrared (NIR) RTP, particularly for those from nonaromatics. Here we demonstrate that succinimide derived cyclic imides can emit RTP in the red (665, 690 nm) and NIR (745 nm) spectral range with high efficiencies of up to 9.2%. Despite their rather limited molecular conjugations, their unique emission stems from the presence of the imide unit and heavy atoms, effective molecular clustering, and the electron delocalization of halogens. We further demonstrate that the presence of heavy atoms like halogen or chalcogen atoms in these systems is important to facilitate intersystem crossing as well as to extend through-space conjugation and to enable rigidified conformations. This universal strategy paves the way to the design of nonconventional luminophores with long wavelength emission and for emerging applications.
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MICROCHIMICA ACTA
·
2022
·Vol. 189
·期 6
·1-9
·
IF 6.408
Fu Yanli,Wei Jia,Yao Shuo,Zhang Liang,Zhang Mingrui,Zhuang Xiangyang,Zhao Chao,Li Juan,Pang Bo
A dual-signal photometric/fluorometric assay was established for rapid, qualitative, and quantitative detection of Salmonella typhimurium ( S. typhimurium ). This method was composed of two parts: (1) a single-step photometric (SSC) assay containing gold nanoparticles (AuNPs), poly-diallyldimethylammonium chloride (PDDA), and S. typhimurium -specific aptamer, and (2) a fluorescence (FL) assay containing carboxyl-modified CdSe/ZnS quantum dots (QDs- COOH ). Users just need to drop samples contaminated with S. typhimurium into SSC assay; the apparent color change from red to blue can be observed in a short time (20 min). A smartphone app was developed to read the semiquantitative result. By subsequently adding one drop of FL assay into the reaction mixture, the generated fluorescence intensity reflected the concentration of S. typhimurium . The naked eye limit of detection (LOD) and fluorescent LOD were 10 3 cfu/mL and 10 cfu/mL, respectively. This method exhibited good selectivity. The reliability and practicability were verified by testing contaminated food, drinking water, and pets’ urine. Graphical abstract
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Journal of Advanced Ceramics
·
2022
·Vol. 11
·期 5
·794-804
·
IF 11.534
Xu Yangsen,Xu Xi,Bi Lei
A high-entropy ceramic oxide is used as the cathode for the first time for proton-conducting solid oxide fuel cells (H-SOFCs). The Fe 0.6 Mn 0.6 Co 0. 6 Ni 0.6 Cr 0.6 O 4 (FMCNC) high-entropy spinel oxide has been successfully prepared, and the in situ chemical stability test demonstrates that the FMCNC material has good stability against CO 2 . The first-principles calculation indicates that the high-entropy structure enhances the properties of the FMCNC material that surpasses their individual components, leading to lower O 2 adsorption energy for FMCNC than that for the individual components. The H-SOFC using the FMCNC cathode reaches an encouraging peak power density (PPD) of 1052 mW·cm −2 at 700 °C, which is higher than those of the H-SOFCs reported recently. Additional comparison was made between the high-entropy FMCNC cathode and the traditional Mn 1. 6 Cu 1.4 O 4 (MCO) spinel cathode without the high-entropy structure, revealing that the formation of the high-entropy material allows the enhanced protonation ability as well as the movement of the O p-band center closer to the Fermi level, thus improving the cathode catalytic activity. As a result, the high-entropy FMCNC has a much-decreased polarization resistance of 0.057 Ω·cm 2 at 700 °C, which is half of that for the traditional MCO spinel cathode without the high-entropy design. The excellent performance of the FMCNC cell indicates that the high-entropy design makes a new life for the spinel oxide as the cathode for H-SOFCs, offering a novel and promising route for the development of high-performance materials for H-SOFCs.
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CHEMICAL RESEARCH IN CHINESE UNIVERSITIES
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2022
·Vol. 38
·期 3
·816-822
·
IF 2.726
Hu Shifan,Wang Yafeng,Su Bin
Electrochemiluminescence(ECL) is a powerful transduction technique used in biosensing and in vitro diagnosis, while the mechanism of ECL generation is complicated and affected by various factors. Herein the effect of ionic strength on ECL generation by the classical tris(2,2′-bipyridyl)ruthenium(II)[Ru(bpy) 3 2+ ]/tri- n -propylamine(TPrA) system was investigated. It is clear that the ECL intensity decreases significantly with the increase of ionic strength, most likely arising from the reduced deprotonation rate of TPrA +· . We further combined microtube electrode(MTE) with ECL microscopy to unravel the evolution of ECL layer with the variation of ionic strength. At a low concentration of Ru(bpy) 3 2+ , the thickness of ECL layer(TEL) nearly kept unchanged with the ionic strength, indicating the surface-confined ECL generation is dominated by the oxidative-reduction route. While at a high concentration of Ru(bpy) 3 2+ , ECL generation is dominated by the catalytic route and TEL increases remarkably with the increase of ionic strength, because of the extended diffusion length of Ru(bpy) 3 3+ at a reduced concentration of TPrA · .
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Journal of Translational Medicine
·
2022
·Vol. 20
·期 1
·1-15
·
IF 8.44
Guan Huanshuai,Kong Ning,Tian Run,Cao Ruomu,Liu Guanzhi,Li Yiyang,Wei Qilu,Jiao Ming,Lei Yutian,Xing Fangze,Tian Peng,Wang Kunzheng,Yang Pei
Background Osteoporosis is a disease threatening the health of millions of individuals. Melatonin is found to be a potential anti-osteoporosis drug. However, whether melatonin plays a role against osteoporosis at different stages of the menopause and the underlying mechanisms are unknown. Methods Ovariectomy was utilized as a model of perimenopausal and postmenopausal osteoporosis. A total of 100 mg/kg melatonin, or solvent alone, was added to the drinking water of the rats over 8 weeks. Perimenopausal rats immediately received intervention following ovariectomy while postmenopausal rats received intervention 8 weeks after ovariectomy. All rats underwent overdose anesthesia following intervention after which blood samples and femurs were collected for further analysis. Rat femurs were scanned using micro-CT and examined histologically. The serum levels of melatonin and osteogenic biochemical markers were measured and the expression of osteogenesis-associated genes ( Runx2 , Sp7 ) were quantified by real-time quantitative PCR. Alkaline phosphatase (ALP) activity and the gene expression ( Col1a1 , Runx2 , Alpl , and Bglap ) were measured after bone marrow mesenchymal stem cells (BMSCs) were osteogenically induced, both with and without melatonin in vitro. ALP staining and Alizarin Red S staining were used to identify osteogenesis. Results Analysis by micro-CT and histological staining demonstrated that bone mass decreased and bone microarchitecture deteriorated over time after ovariectomy. Intervention with melatonin increased bone mass in normal, perimenopausal, and postmenopausal osteoporotic rats. Serum levels of ALP continuously increased after ovariectomy while osteocalcin levels initially rose, then decreased. Melatonin increased the serum levels of ALP and osteocalcin and mRNA expression levels of Runx2 and Sp7 in normal and postmenopausal rats, the opposite of the markers in perimenopausal rats. In vitro study demonstrated that 100 μmol/L melatonin increased the mRNA expression of Col1a1 , Runx2 , and Alpl three and/or seven days after intervention, and Alpl and Bglap 14 d after intervention. Melatonin increased ALP activity and the extent of ALP and matrix mineralization in the late stage of osteogenesis. Conclusions Bone mass continuously decreased after ovariectomy, while melatonin increased bone mass and ameliorated bone metabolism in normal, perimenopausal, and postmenopausal osteoporotic rats due to the induction of osteogenic differentiation in BMSCs.
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Environmental Chemistry Letters
·
2022
·Vol. 20
·期 4
·2253-2259
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IF 13.615
Shi En,Wang Xinyu,Zhang Miao,Wang Xin,Gao Jianchun,Zheng Yunbin
Wastewater treatment generates increasing amounts of unwanted sewage sludges, calling for advanced recycling methods. Here, we transformed sewage sludge into activated carbon by molten salt synthesis with ZnCl 2 . We analyzed the structure and specific surface area of sludge-derived activated carbon by Fourier transform infrared spectroscopy and Brunauer–Emmett–Teller analysis. Results show that the mass ratio of ZnCl 2 to sludge had a significant effect on the textural properties and adsorption performance of sludge-derived activated carbon. The maximum specific surface area was 549.72 m 2 /g, and the carbon utilization potential was 178.56 mg (C atom) /g (sludge) , for a mass ratio of ZnCl 2 to sludge of the total carbon mass in sludge-derived activated carbon adsorbed CO 2 and methylene blue can be achieved to 186.68 and 203.18 mg (C atom) /g (sludge) , respectively.
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JOURNAL OF ELECTRONIC MATERIALS
·
2022
·Vol. 51
·期 5
·2652-2662
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IF 2.047
Xiao Zhen,Guo Rui,He Xinping,Gan Yongping,Zhang Jun,Huang Hui,Zhang Wenkui,Wang Bingjia,Han Yi,Xia Yang
Carbon-based conductive polymer composites are thriving as promising electrothermal materials for a vast array of applications. However, the low working temperature (< 100°C) of most carbon-based conductive polymer composites due to the low melting point and inferior temperature resistance of polymer matrix severely restricts their high-temperature applications. Herein, a series of thin electric heating films composed of highly thermally stable polybenzimidazole (PBI) as polymer matrix and low-cost carbon black nanoparticles (Super P, SP) as conductive fillers are successfully developed to significantly increase the maximum working temperature as high as >200°C under relatively low applied voltage. The morphology, microstructure, electrical properties, and electrothermal behavior of the PBI/SP composites are systematically studied as a function of SP content. By introducing 15–25 wt.% SP conductive fillers, SP nanoparticles with uniform spatial dispersion are tightly anchored on the surface and tip of fiber-like villous PBI matrix, forming continuous highly conductive networks. However, the conductive filler content exceeds to 30 wt.%, and SP nanoparticles tend to locally clump together in aggregation, resulting in potential safety issues. Impressively, PBI/SP composite with 25 wt.% SP content (PBI/SP-25) exhibits superior electrothermal performance, including rapid temperature responsiveness, high maximum working temperature, superior heating uniformity, and remarkable electrothermal reproducibility. As an integrated thin-film heater for water boilers, PBI/SP-25 electrothermal film heats 100 ml of water to 99.5°C within 4 min at 25 V, demonstrating great potential in household electrical appliances.
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Biomass Conversion and Biorefinery
·
2022
·
IF 4.05
Zhang Sinan,Wang Jihong,Wang Shuhua,Leng Su
Contamination of chlortetracycline (CTC) in water is a global problem that needs to be addressed urgently. Biochar immobilization of microorganisms is an effective way to remove CTC contamination from sewage. In this study, the CTC removal effect of free bacteria LZ01 and erding medicine residues biochar immobilized LZ01 was compared by shake flask batch experiments. The results showed that immobilized LZ01 significantly improved the CTC removal rate by 15.27% compared to free LZ01. The immobilization of LZ01 also significantly improved the environmental tolerance and the reusability and storage stability of strain LZ01. The optimal conditions for CTC removal (83.83%) by immobilized LZ01 were determined by response surface methodology: temperature of 33.98 °C, pH of 7.84, initial CTC concentration of 73.75 mg/L, and inoculation dose of 0.51% (w/v). The experimental results of treating CTC from simulated sewage showed that the immobilized LZ01 could remove more than 64% of CTC from the sewage. The ion of Cu 2+ accelerated the removal of CTC by immobilized LZ01, and the removal rates could reach 81.07%, 85.07%, and 87.50% in three sewages, i.e., river sewage, pond water, and farming wastewater, respectively. This study provides a feasible, effective, and rapid biological removal technique for the treatment of CTC pollution in sewage.
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Nano-Micro Letters
·
2022
·Vol. 14
·期 1
·1-14
·
IF 23.655
Wu Wanbao,Bo Yiyang,Li Deping,Liang Yihong,Zhang Jichuan,Cao Miaomiao,Guo Ruitian,Zhu Zhenye,Ci Lijie,Li Mingyu,Zhang Jiaheng
Highlights
A novel amide-based nonflammable electrolyte is proposed. The formation mechanism and solvation chemistry are investigated by molecular dynamics simulations and density functional theory.
An inorganic/organic-rich solid electrolyte interphase with an abundance of LiF, Li 3 N and Li–N–C is in situ formed, leading to spherical lithium deposition.
The amide-based electrolyte can enable stable cycling performance at room temperature and 60 ℃.
Abstract The formation of lithium dendrites and the safety hazards arising from flammable liquid electrolytes have seriously hindered the development of high-energy-density lithium metal batteries. Herein, an emerging amide-based electrolyte is proposed, containing LiTFSI and butyrolactam in different molar ratios. 1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropylether and fluoroethylene carbonate are introduced into the amide-based electrolyte as counter solvent and additives. The well-designed amide-based electrolyte possesses nonflammability, high ionic conductivity, high thermal stability and electrochemical stability (> 4.7 V). Besides, an inorganic/organic-rich solid electrolyte interphase with an abundance of LiF, Li 3 N and Li–N–C is in situ formed, leading to spherical lithium deposition. The formation mechanism and solvation chemistry of amide-based electrolyte are further investigated by molecular dynamics simulations and density functional theory. When applied in Li metal batteries with LiFePO 4 and LiMn 2 O 4 cathode, the amide-based electrolyte can enable stable cycling performance at room temperature and 60 ℃. This study provides a new insight into the development of amide-based electrolytes for lithium metal batteries.
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