NEW JOURNAL OF CHEMISTRY
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2018
·Vol. 42
·期 18
·15121-15126
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IF 3.201
Jie Yang,Zhongming Huang,Yalei Hu,Jia Ge,Jianjun Li,Zhaohui Li
Uric acid (UA) is an important biological molecule in human pathology and is related to many critical diseases. Designing a simple and rapid method for sensitive UA determination is of great significance. Herein, we report a novel turn-on fluorescence assay for UA detection, based on fluorescence resonance energy transfer (FRET) between carbon dots (C-dots) and MnO2 nanosheets. MnO2 nanosheets can adsorb C-dots to form nanocomposites, where the fluorescence of C-dots is quenched via FRET. Fluorescence recovered when UA was introduced into the sensing system due to the decomposition of MnO2 nanosheets to Mn2+. Under optimized conditions, the fluorescence signal was linearly related to UA concentration in the range of 0.1–200 μM and the detection limit was as low as 45 nM. Moreover, this developed assay was successfully applied for human urine sample analysis, which indicated that this strategy could be an efficient tool for clinical disease diagnosis.
研究领域:
生物化学
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医学诊断
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材料科学
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高影响因子
Advanced Materials Technologies
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2023
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IF 6.8
Zijian Shao,Wenjie Wang,Yilin Wang,Weifeng Zhao,Changsheng Zhao
Complex immune microenvironment of diabetic wound possesses polarization misalignment of macrophages and excessive inflammatory response, which prolong the healing process. Consequently, developing hydrogel dressings with immunoregulatory ability shows huge potential in clinical management of diabetic wound. Nevertheless, recent immunoregulatory strategies are mainly focusing on switching the proinflammatory M1-type to anti-inflammatory M2-type macrophages by using high-cost dressings composed of cytokines and cells. Considering the hyperpolarized M1 macrophages of diabetic wounds as wild grass of wasteland, a burning grass and removing root immunoregulatory strategy toward wound healing is developed based on dopamine-manganese dioxide nanoparticle incorporated high molecular weight hyaluronic acid (HHA) hydrogel. The self-healing and injectable hydrogel is formed by boronate ester bonds between the HHA grafted with phenylboronic acid and polyvinyl alcohol. Notably, in vitro and vivo results confirm that the HHA components can burn the grass by switching M1 to M2 in the inflammatory microenvironment while the dopamine-manganese dioxide nanoparticles can remove the root by relieving M1 polarization through eliminating reactive oxygen species. The comprehensive immunoregulation ability enables the hydrogel as effective therapeutic that improves wound healing, and shows reliable potential in clinical dressings for the management of diabetic wounds.
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CERAMICS INTERNATIONAL
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2023
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IF 5.2
Fen Qiao,Wenjie Liu,Shuihua Yu,Qiaoling Zhang,Guodong Li,Huaqiang Chu
Mn 2 O 3 is and has received widespread attention in fields such as catalysis and energy storage. However, its poor conductivity limits its application as an electrode material for supercapacitors. Here, flower-like spheroidal δ-MnO 2 /Mn 2 O 3 composites composed of two-dimensional (2D) hierarchical nanosheets were prepared by the template method and a simple hydrothermal process. The growth process and electrochemical properties of δ-MnO 2 /Mn 2 O 3 composites were investigated by adjusting the concentration of KMnO 4 in the hydrothermal process. Since the introduction of δ-MnO 2 brings more pseudocapacitance to the composite, the synergistic effect between MnO 2 and Mn 2 O 3 reduces the interfacial resistance, and the unique nanosheet structure increases its specific surface area, which alleviates the volume expansion during the cycling, the δ-MnO 2 /Mn 2 O 3 composite electrode exhibits high specific capacitance (182 F g −1 at 0.5 A g −1 ), fast rate performance (74.2% capacitance retention at 5 A g −1 ), and excellent cyclic stability (90.1% capacitance retention after 5000 cycles at 5 A g −1 ). Symmetric supercapacitors assembled with δ-MnO 2 /Mn 2 O 3 electrodes also exhibit a high energy density of 9.1 Wh kg −1 . δ-MnO 2 /Mn 2 O 3 composites have greater application prospects in energy storage, and are expected to achieve further applications in lithium/sodium ion batteries, zinc ion batteries and other fields.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2023
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IF 22.1
Haiyu Wang,Linghui Peng,Guiying Li,Hongli Liu,Zhishu Liang,Huijun Zhao,Taicheng An
Catalytic ozonation is a promising bioaerosol control technology, as O 3 is prevalent in atmosphere. However, O 3 at atmosphere concentration has limited oxidation potential and reactive oxygen species (ROSs) production, leading incomplete bioaerosol inactivation. Therefore, a catalytic ozonation system with a manganese dioxide/Ni foam (MN) was prepared for efficient bioaerosol inactivation. The MN exhibited superior activity in catalytic ozonation bioaerosol inactivation, achieving 91.6% inactivation efficiency within 8.07 s at atmospheric concentration (0.1 ppm) of O 3 . The inactivation efficiency can be further improved to 99.0% by regulating surface oxygen vacancies (O V ) in MN, which is mainly attributed to abundant O V of MN that facilitate rapid conversion of O 3 to other ROSs. Meanwhile, the mechanism of rapid bacterial inactivation was also clarified at cellular level, showing that ROSs caused bacterial oxidative stress. This catalytic ozonation strategy would offer more choices to design efficient O 3 catalysts for bioaerosol control and public health protection.
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Crystals
·
2023
·Vol. 13
·期 12
·1664
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IF 2.7
Yulong Chen,Yuan Chi,Xiao Wu,Cong Lin,Tengfei Lin,Min Gao,Chunlin Zhao,Baisheng Sa
The widespread use of pharmaceuticals and personal care products (PPCPs) in many fields has brought convenience to human lives but has also caused unavoidable environmental pollution issues. In particular, the resistance gene problem resulting from accumulating antibiotics that cannot be fully absorbed by biological individuals has been a concern; thus, it is urgent to find efficient technologies to boost the degradation efficiency of antibiotics in the environment. Here, an ε-MnO2catalyst was prepared by a novel droplet-interface-drying method and utilized as a Fenton-like catalyst for efficiently degrading ciprofloxacin (CIP). The ε-MnO2shell was formed preferentially at the gas–liquid interface and then continued to decompose into ε-MnO2with abundant O vacancies in the air-insulated microcavity. The XPS result confirms that this particular preparation method can regulate the content of O vacancies in the material. Compared with ε-MnO2samples obtained by the direct drying method (ε-MnO2-B), the catalytic performance of ε-MnO2prepared by the droplet-interface-drying method (ε-MnO2-P) is significantly improved. By activating peroxymonosulfate (PMS) with the ε-MnO2-P catalyst, the CIP degradation efficiency can reach 84.1%. The detection and analysis of reactive oxygen species (ROS) in the ε-MnO2-P/PMS oxidation system confirms that ·OH, SO4·−and1O2are the main ROS for CIP degradation. This study highlights the creation of miniature hypoxic space to regulate the content of O vacancies in ε-MnO2, providing a new idea for the synthesis of other O-vacancy-rich materials.Keywords:droplet-interface-drying method;Fenton-like oxidation;ε-MnO2;ciprofloxacin;water purification
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SENSORS AND ACTUATORS B-CHEMICAL
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2023
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IF 8.4
Anni Cui,Yiting Hou,Jialu Zhang,Xin Mu,Huan Wang,Yu Sun,Haitao Xu,Guiye Shan
Staphylococcus aureus (S. aureus) infections pose a serious threat to human health worldwide. Therefore, selective and accurate detection of S. aureus is necessary for preventing infections. Herein, we design the colorimetric-electrochemical sensing platform based on specific oligonucleotide (SA31 aptamer)-tunable oxidase-like activity of mesoporous polydopamine/MnO 2 (MPDA/MnO 2 ) nanozymes for the S. aureus detection. The MPDA/MnO 2 nanozymes possess excellent oxidase-like activity and electrochemical property. MPDA/MnO 2 nanozymes can catalyze the oxidation of TMB to generate TMB + (blue color) and TMB 2+ (yellow color) products. The oxidase-like activity of MPDA/MnO 2 can be inhibited when the SA31 is adsorbed on the surface of the nanozymes. In the presence of S. aureus, SA31 aptamer desorbs from MPDA/MnO 2 surface based on the specific identification between S. aureus and aptamer, resulting in the recovery of their oxidase-like activity. Based on the different oxidative degree of TMB, the color of sensing solution changes from blue to yellow, the electrochemical signals also have changed simultaneously. The colorimetric-electrochemical sensing platform can accurately detect S. aureus, showing a low detection limit in 3 CFU/mL (S/N = 3). Furthermore, the dual-mode sensing platform can be utilized for the accurate and specific detection of S. aureus in real sample with the recovery of 95.15%− 115.28%. This work based on SA31 aptamer-tunable oxidase-like activity of MPDA/MnO 2 nanozymes provides a dual-mode assay for specific and accurate detection of S. aureus.
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FOOD CHEMISTRY
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2023
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IF 8.8
Fei Tong,Zan Yang,Zheng Wang,Wenya Liu,Wanqi Jiang,Lu Zhu,Lei Wang,Mingming Zheng,Ruyan Hou,Yibin Zhou,Yingnan Liu
In view of the potential hazards of organophosphorus pesticides (OPs), this paper constructed a ratiometric fluorescent probe utilizing a functionalized metal–organic framework to detect OPs. Ru(bpy) 3 Cl 2 was encapsulated inside UiO-66 as a reference signal, and MnO 2 nanosheets (MnO 2 NSs) were grown on the surface to obtain [email protected] @MnO 2 NSs. Acetylcholinesterase catalyzed the decomposition of acetylcholine into reductive thiocholine, which consumed MnO 2 NSs, thus restoring the [email protected] fluorescence. Due to the enzymatic inhibition of OPs and the redox reaction between MnO 2 NSs and thiamine, this probe emitted blue fluorescence in the presence of OPs. The probe achieved linear responses to dichlorvos and chlorpyrifos with LODs of 9.99 × 10 -6 μg mL −1 and 9.99 × 10 -5 μg mL −1 . The probe exhibited a satisfactory recovery rate for OPs in green tea. Furthermore, a hydrogel detection platform was developed by embedding the probe into sodium alginate. Overall, this work provides a visual approach to detect OPs in agricultural products.
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PubMed
高影响因子
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
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2023
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IF 4.9
Feng Qian,Zongwang Huang,Wenbin Liu,Yanling Liu,Xi He
Segmental bone defects caused by trauma, tumor resection or congenital malformations are often reconstructed with autologous, allogeneic bone grafts or artificial bone materials, of which, about 5% ~ 10% will have delayed healing or even nonunion of fractures. The loss of periosteum and excessive accumulation of ROS in fracture site leads to the aging of osteoblasts and the decline of their proliferation and differentiation, thus affecting the fracture healing process. In this study, we prepared a functional modified artificial periosteum β-TCP/MnO 2 /PCL(β-TMP) by electrospinning with a function of catalyzing decomposition of H 2 O 2 . We examined the surface morphology of β-TMP, the concentration of Ca, P and Mn of β-TMP, as well as the diameter distribution range of nanofibers on β-TMP. Through X-ray diffraction patterns and Fourier transform infrared spectra, β-TMP was characterized and its hydrophilicity was tested. The release of Mn 2+ and Ca 2+ of 0.1 and 0.05% β-TMP in different pH values (7.4 and 5.5) determined by ICP. We also identified that β-TMP could reduce the level of ROS in cells by lowering the level of H 2 O 2 . 0%, 0.05% and 0.1% β-TMP displayed good cell compatibility, cell adhesion and cellular morphology in the condition with or without H 2 O 2 . 0.5% β-TMP showed compromised cell compatibility in normal condition, however, the compromised phenotypes could be partially rescued in the present of H 2 O 2 . Compared with 0%, 0.05% and 0.1% β-TMP displayed higher osteoblastic differentiation with or without H 2 O 2 in BMSCs as well as in MG-63. In sum, β-TMP helped osteogenesis and promoted repair of bone defects.
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PubMed
高影响因子
Environmental Science-Nano
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2023
·Vol. 10
·期 5
·1428-1440
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IF 7.3
Xixi Chen,Yanjun Li,Wanyi Fu,Shuanghong Tian,Yulong Yang,Kai Yang,Xuanbo Xu,Xihui Zhang
The importance of nonradical Fenton-like catalysis in environmental fields has motivated research for effective singlet oxygen (1O2) production, but realizing the accurate design and regulation of active sites for manipulating oriented 1O2 generation is still highly challenging. In this study, α-, β-, and γ-MnO2 catalysts with different oxygen vacancy (OV) abundance were fabricated to activate H2O2 to generate 1O2 for the degradation of oxytetracycline (OTC). The OV-rich α-MnO2 had a high OTC removal efficiency (>93.5%) at the pH range from 4.0 to 11.0. Moreover, α-MnO2 exhibited great applicability for a real water matrix, and the total removal of various kinds of emerging contaminants from hospital wastewater reached up to 97.4%. The excellent performances of α-MnO2 were attributed to the rich contents of OVs that induced the oriented generation of 1O2. Theoretical density functional theory (DFT) calculations validated that the OV-rich α-MnO2 had the highest H2O2 adsorption ability (−1.39 eV) and the lowest energy barrier (0.41 eV) for the dissociation of *OH to form the *O intermediate, which promoted the oriented formation of 1O2. This work provides a strategy of manipulating the oriented generation of 1O2 towards water decontamination via regulating the abundance of oxygen vacancies in α-MnO2 nanocatalysts.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2023
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IF 5.2
Jiahao Zheng,Yuyin Yang,Zhaolong Dai,Jingsong Wang,Yulin Xia,Chenxu Li
Strontium ion in radioactive wastewater causes serious harm to the biological and ecological environment, so the removal of strontium ion is of great significance. We have prepared an inorganic adsorption material (MnO 2 /HMSS) by impregnation method. The adsorbent can effectively remove Sr 2+ in radioactive wastewater. The synthetic materials were characterised by X-ray diffraction (XRD), Scanning electron microscope (SEM), X-ray spectroscopy (EDS), Fourier-transform infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy (XPS) and N 2 adsorption-desorption isotherms. The effects of the mass ratio of manganese dioxide and hollow mesoporous silica spheres, pH, initial concentration of Sr 2+ , adsorption time, competitive ion and other parameters on the adsorption properties were systematically investigated. The results showed that the 4:1Mn0 2 /HMSS composite had the highest adsorption capacity. The adsorption of Sr 2+ on MnO 2 /HMSS is highly dependent on pH and initial solubility. Furthermore, the adsorption equilibrium is reached at 120 min, with a maximum adsorption capacity of 138.70 mg/g. In addition, the composite still maintains a good adsorption capacity under a variety of competitive ions. The Langmuir and pseudo-second-order models can better fit the adsorption isotherm and kinetic data than the Freundlich and pseudo-first-order models, respectively. The new composite obtained in this work has the advantages of rapid adsorption, large adsorption capacity, strong selectivity and capable of large-scale preparation, which makes it expected to play an important role in the removal of strontium ions.
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ACS Applied Nano Materials
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2023
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IF 5.9
Shanyi Wang,Weihao Jin,Yujia Wu,Wanzhen Li,Yugui Tao,Jun Wang,Kai Yang,Weiwei Zhang,Lin Gui,Fei Ge
Drug-resistant bacterial infections pose a significant threat to global public health. Furthermore, the formation of biofilms makes traditional antibiotic treatments significantly less effective in killing multidrug-resistant (MDR) bacteria. In this work, we prepared a molybdenum disulfide (MoS2) nanosphere-based nanocomposite that utilized both photothermal therapy (PTT) and chemodynamic therapy (CDT) for effectively eradicating biofilms. A layer of manganese dioxide (MnO2) was adsorbed onto the surface of the MoS2 nanospheres by redox and electrostatic adsorption methods, and the resulting MoS2/MnO2 were loaded with 2,2′-azobis[2-(2-imidazolin-2-yl)propane]-dihydrochloride (AIPH) to form the MoS2/MnO2-AIPH nanocomposite (MMA). The microenvironment of biofilms is slightly acidic, lacks oxygen, and has a high concentration of glutathione (GSH). The MnO2 was capable of reacting with GSH to deplete it while also generating •OH radicals for CDT. In the presence of NIR light (808 nm), the temperature increase brought about by PTT further enhanced the CDT efficacy synergistically. The results showed that the photothermal conversion efficiency of the MMA was 40.5% at a concentration of 100 μg/mL, and the biofilm eradication rate of both MDR Escherichia coli and MDR Staphylococcus aureus was above 90%. The high bacterial inhibition rate (above 96%), as well as the excellent biosafety and biocompatibility of the MMA nanocomposite enabled it to effectively promote wound healing, which has significant implications in treating bacterial infections and promoting wound healing in clinical settings.
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Biosensors-Basel
·
2023
·Vol. 13
·期 5
·563
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IF 5.4
Yanqing Wu,Tao Zhang,Lishen Su,Xiaoping Wu
Herein, a simple and portable electrochemical sensor based on a reduced graphene oxide/gold nanoparticle/manganese dioxide (rGO/AuNP/MnO2) nanocomposite-modified screen-printed carbon electrode (SPCE) was constructed by the facile stepwise electrodeposition method and used for electrochemical detection of As(III). The resultant electrode was characterized for its morphological, structural, and electrochemical properties using scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), energy dispersive X-ray spectroscopy (EDX), cyclic voltammetry (CV), and electrochemical impedance spectroscopy (EIS). From the morphologic structure, it can be clearly observed that the AuNPs and MnO2alone or their hybrid were densely deposited or entrapped in thin rGO sheets on the porous carbon surface, which may favor the electro-adsorption of As(III) on the modified SPCE. It is interesting that the nanohybrid modification endows the electrode with a significant decrease in charge transfer resistance and an increase in electroactive specific surface area, which dramatically increases the electro-oxidation current of As(III). This improved sensing ability was ascribed to the synergistic effect of gold nanoparticles with excellent electrocatalytic property and reduced graphene oxide with good electrical conductivity, as well as the involvement of manganese dioxide with a strong adsorption property in the electrochemical reduction of As(III). Under optimized conditions, the sensor can detect As(III) via square wave anodic stripping voltammetry (SWASV) with a low limit of detection of 2.4 μg L−1and a linear range of 25–200 μg L−1. The proposed portable sensor shows the advantages of a simple preparation procedure, low cost, good repeatability, and long-term stability. The feasibility of rGO/AuNPs/MnO2/SPCE for detecting As(III) in real water was further verified.Keywords:electrochemical sensor;gold nanoparticles;metal oxides;nanocomposites;reduced graphene oxide;screen printed carbon electrode;arsenic
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高影响因子
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