Analytical Methods
·
2020
·Vol. 12
·期 17
·2237-2243
·
IF 2.596
Yujiao Tu,Suping Wang,Xiaotian Yuan,Pengfei Song,Yunlin Wei,Kunhao Qin,Qi Zhang,Xiuling Ji
Novel fluorescent nitrogen and phosphorus-doped carbon dots (Aa N,P-CDs) derived from Auricularia auricula were successfully prepared via a simple hydrothermal method. The Aa N,P-CDs showed high selectivity and sensitivity in detection of 4-nitrophenol (4-NP) and Ag(I) and good linear ranges of 4-NP (0–37.5 μM, R2 = 0.9967) and Ag(I) (0–25 μM, R2 = 0.9934). The low detection limits were 198 nM and 74.35 nM, respectively. This showed that static quenching dominated in Ag(I) quenching of the Aa N,P-CD fluorescence, while that of 4-NP was the inner filter effect. The Aa N,P-CDs were successfully used to detect 4-NP and Ag(I) in real water and soil samples. Cell imaging indicated that Aa N,P-CDs showed low biotoxicity and good biocompatibility, which provided a new insight into bioimaging application and environmental pollutant detection.
✓ 已验证
产品关联
DOI
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2020
·
IF 5.774
Longqian Xu,Linghui Zhao,Yunfeng Mao,Zhen Zhou,Deli Wu
Copper-iron bimetallic material shows a high reactive activity in dioxygen activation processes (DOAs) but presents a significant challenge for enhancing superoxide radical ( • O 2 − ) generation. In this study, a practical strategy was developed to enhance • O 2 − generation for BPA degradation using a zeolite-supported Cu-Fe bimetallic system (called Cu/Fe@zeolite), which was simply prepared by impregnation method. The results verified that the Cu(I) regeneration at the zeolite surface contributes • O 2 − generation and the H 2 O 2 that is further generated induces • OH production via a further Fenton reaction. In the reaction process, the initial generation of • O 2 − was primarily enhanced by the Cu(I) loaded onto the zeolite surface and the adsorbed BPA was easily degraded by the •OH. Under optimal operating conditions (i.e., Cu/Fe@zeolite = 3 g/L, Cu:Fe = 1:2, pH = 5, t = 120 min), it was found that 87% of BPA can be removed from wastewater. It is also important to note that the weak alkali buffering property of zeolite not only provides BPA adsorption sites under acidic conditions but also accelerates the precipitation efficiency for metallic ions and reduced the adverse effect of metallic residue on the effluent quality.
✓ 已验证
产品关联
DOI
高影响因子
Nanomaterials
·
2020
·Vol. 10
·期 6
·1112
·
IF 4.324
Wenjuan Guo,Ahmad Umar,Yankai Du,Luyan Wang,Meishan Pei
Poly(2-(dimethylamino)ethyl methacrylate)-grafted bentonite, marked as Bent-PDMAEMA, was designed and prepared by a surface-initiated atom transfer radical polymerization method for the first time in this study. Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM) and thermal gravimetric analysis (TGA) were applied to characterize the structure of Bent-PDMAEMA, which resulted in the successful synthesis of Bent-PDMAEMA. As a cationic adsorbent, the designed Bent-PDMAEMA was used to remove dye Orange I from wastewater. The adsorption property of Bent-PDMAEMA for Orange I dye was investigated under different experimental conditions, such as solution pH, initial dye concentration, contact time and temperature. Under the optimum conditions, the adsorption amount of Bent-PDMAEMA for Orange I dye could reach 700 mg·g−1, indicating the potential application of Bent-PDMAEMA for anionic dyes in the treatment of wastewater. Moreover, the experimental data fitted well with the Langmuir model. The adsorption process obeyed pseudo-second-order kinetic process mechanism.Keywords:PDMAEMA;polymer brushes;Orange I;dyes removal;water treatment
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 8
·1-13
·
IF 6.232
Min Jie,Qu Xiang-Long,Yan Bing
A novel fluorescent and electron-deficient hybrid, N -methylated [Eu (pddb)phen(ox) 0.5 ] n (Eu-MOF-Me) has been prepared via post-synthetic modification. Considering its special luminescent properties and cationic framework, Eu-MOF-Me is developed as a visualized fluorescent probe. Notably, water-stable Eu-MOF-Me exhibits advantages like good structural and fluorescent stability in a wide range of pH value (3.39–10.86), excellent identification ability for F − , I − , and S 2− (it can easily distinguish F − and I − from other halogen ions and can realize naked eye identification of F − , I − , and S 2− ), relatively low detection limits (6.61 μM for S 2− , 7.57 μM for F − ), and reusability. More importantly, it has been utilized for the construction of a Boolean logic gate system. In this system, Eu-MOF-Me serves as the gate, by taking F − , I − , and S 2− as the inputs and fluorescence emission bands (UV380, B437, and R612) as the outputs; some primary logic gates (NOR, IMP, YES, NOT) and the combination of them have been realized. Moreover, we achieved a cascaded logic gate (NOR+OR). For further application, a molecular computing keypad-lock security system has been obtained.
A novel fluorescent and electron-deficient hybrid named Eu-MOF-Me has been prepared via post-synthetic methylation. Considering its special luminescent properties and cationic framework, Eu-MOF-Me was developed as a fluorescent probe for the visual monitoring of important anions. In addition, it was used for the construction of Boolean logic library and a keypad-lock system was achieved
✓ 已验证
产品关联
DOI
PubMed
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2020
·
IF 10.257
Guihua Zhang,Li Zhang,Ying Yu,Bixia Lin,Yumin Wang,Manli Guo,Yujuan Cao
Diversified determination of cardiac troponin I (cTnI) in serum is of great significance for the clinical diagnose and daily monitoring of acute myocardial infarction. Herein, an electrochemical-colorimetric dual-mode imprinted sensing strategy was proposed. Firstly, the aptamer-functionalized Fe 3+ -polydopamine ( [email protected] 3+ -PDA) was constructed as the self-sacrifice beacon. Furthermore, an epitope magnetic molecularly imprinted polymer was prepared to recognize cTnI. Once the cTnI was captured, the beacon was then bound to it through the aptamer , which formed a sandwich-like complex. Under acidic condition, the [email protected] 3+ -PDA was disintegrated to release large amount of Fe 3+ , and further converted to Prussian blue (PB). On one hand, the electrochemical response of the PB was sensitive to the cTnI amount. On the other hand, the addition of the yellow K 3 [Fe(CN) 6 ] into different amounts of the produced PB was able to result in different colors, which enabled the visual detection of cTnI. Under the optimal condition, the sensing strategy exhibited a linear range from 1.0 × 10 −2 to 1.0 × 10 3 ng mL −1 , and the detection limits were 3.2 and 7.4 pg mL −1 for the electrochemical and colorimetric modes, respectively. Besides, It is demonstrated that the dual-mode strategy shows favorable selectivity and stability in the assays, indicating a diversified application prospect in both clinic analysis and daily care.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2023
·Vol. 58
·期 12
·6386-6398
·
IF 3.3
Zi-wei Liu,Jun-ru Qi,Ya-ting Song,Cheng-wei Ruan,Jin-song Liao
Summary The properties of pectin extracted by enzyme-assisted nitric acid (EAE-N) and pectin extracted by enzyme-assisted oxalic acid (EAE-O) were analysed and compared with pectin extracted by nitric acid (AE-N) and pectin extracted by oxalic acid (AE-O) systematically. The yield of pectin obtained by the enzyme-assisted acid method (23.73% ~ 25.60%) was significantly higher than that by acid extraction method (19.75% ~ 20.60%). Monosaccharide analyses demonstrated that the enzyme-assisted acid method was able to attain more branched rhamnogalacturonan I (RG-I) regions (36.59% ~ 42.06%) than using acid solely (31.01% ~ 34.58%). Fourier transform infrared spectroscopy (FT–IR) and nuclear magnetic resonance ( 1 H NMR) analyses indicated that there was no obvious difference in the characteristic structure of pectin. The atomic force microscopy (AFM) images revealed that EAE-N and EAE-O had more short side chains and cross-link compared with AE-N and AE-O. Thermogravimetric analysis (TGA) shows that EAE-N and EAE-O have good thermal stability. All pectin samples showed a shear-thinning fluid flow behaviour and an elastic gel-like behaviour. The results suggested that enzyme-assisted acid provided a viable alternative method for the extraction of pectin.
✓ 已验证
产品关联
DOI
高影响因子
ACS Applied Materials & Interfaces
·
2023
·
IF 9.5
Fengmei Zhu,Yuan Gao,Chunli Zhao,Jiacheng Pi,Jianbei Qiu
Near-infrared phosphor-converted light-emitting diodes (NIR pc-LEDs) offer numerous advantages, including compact size, tunable emission spectra, energy efficiency, and high integration potential. These features make them highly promising for various applications, such as night vision monitoring, food safety inspection, biomedical imaging, and theragnostics. All-inorganic halide double-perovskite materials, known for their large absorption cross section, excellent defect tolerance, and long carrier diffusion radius, serve as unique matrices for constructing near-infrared fluorescent materials. In this study, we successfully prepared the all-inorganic metal halide double-perovskite Cs2NaYCl6:Cr3+ using a grinding–sintering method. A small fraction of the [YCl6] octahedra within the host material’s lattice was substituted with Cr3+ ions, resulting in the creation of the Cs2NaYCl6:Cr3+ phosphor. When excited with λ = 310 nm UV light, the phosphor exhibited a broad emission range spanning from 800 to 1400 nm, covering the NIR-I and NIR-II regions. It had a broad bandwidth emission of 185 nm and achieved a fluorescence quantum yield of 20.2%. The unique broadband emission of the phosphor originates from the weak crystal field environment provided by the Cs2NaYCl6 host matrix, which enhances the luminescence properties of the Cr3+ ions. To create NIR pc-LEDs, the phosphor was encapsulated onto a commercially available UV LED chip operating at 310 nm. The potential application of these NIR pc-LEDs in night vision imaging was successfully validated.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Materials Chemistry Frontiers
·
2023
·Vol. 7
·期 17
·3657-3667
·
IF 7
Lirong Wang,Ji Qi,Ke Zhang,Zeyan Zhuang,Keke Ding,Xu Chen,Hong Shan,Dan Ding,Anjun Qin,Ben Zhong Tang
Fluorescence and magnetic resonance imaging (FL/MRI) has received much attention due to their complementary characteristics. However, the simultaneous enhancement of fluorescence and MR signals plus the efficacy of the treatment is still a major challenge. To tackle this difficulty, we put forward a strategy of aggregation and de-aggregation based on luminogens with aggregation-induced emission (AIE) features. NIR II photosensitizer 4,4′-(6,7-diphenyl-[1,2,5]thiadiazolo[3,4-g]quinoxaline-4,9-diyl)bis(N,N-diphenylaniline) (TQ-TPA) with type I reactive oxygen species (ROS) generation ability and amphiphilic 2TPE-Gd were synthesized, and both of them showed the AIE feature. During the construction of nanomicelles, hydrophobic TQ-TPA spontaneously aggregated into the core of the nanomicelles formed by 1,2-distearoyl-sn-glycerol-3-phosphoethanolamine-N-methoxy(polyethylene glycol)-2000 (DSPE-PEG). Meanwhile, aggregates of 2TPE (tetraphenylethylene)-Gd in aqueous solution could be de-aggregated and inserted into the interface, and formed TGdTT nanomicelles (NMs). Based on this strategy and the AIE feature, the TGdTT NMs exhibited strong NIR II fluorescence and type I ROS generation ability, and enhanced T1 relaxivity (r1). Moreover, in vitro, in vivo, and pharmacokinetics results demonstrated that these nanomicelles have good biosafety and a long blood circulation time. Finally, they allowed successful realization of complementary MR/NIR II fluorescence dual-modal imaging-guided photodynamic therapy (PDT) to inhibit tumor growth. This work demonstrated that the aggregation and de-aggregation strategy of AIEgens in core–shell nanomicelles is very attractive for constructing multifunctional theranostic probes.
✓ 已验证
产品关联
DOI
高影响因子
Foods
·
2023
·Vol. 12
·期 8
·1668
·
IF 5.2
Haibo Zhou,Sen Zhang,Lianghua Chen,Yimei Liu,Luhong Shen,Jiuliang Zhang
For many centuries, Gardenia (Gardenia jasminoidesEllis) was highly valued as a food homologous Chinese herbal medicine with various bioactive compounds, including crocin I and geniposide. However, the functional mechanism underlying the hypoglycemic effect of gardenia is absent in the literature. To evaluate the effect of gardenia and its different extracts on type 2 diabetes mellitus (T2DM) in in vivo and in vitro experiments, the dried gardenia powder was extracted using 60% ethanol and eluted at different ethanol concentrations to obtain the corresponding purified fragments. After that, the active chemical compositions of the different purified gardenia fragments were analyzed using HPLC. Then, the hypoglycemic effects of the different purified gardenia fragments were compared using in vitro and in vivo experiments. Finally, the different extracts were characterized using UPLC-ESI-QTOF-MS/MS and the mass spectrometric fragmentation pathway of the two main compounds, geniposide and crocin I, were identified. The experimental results indicated that the inhibitory effect of the 40% EGJ (crocin I) on the α-glucosidase was better than the 20% EGJ (geniposide) in vitro. However, the inhibitory effect of geniposide on T2DM was better than crocin I in the animal experiments. The different results in vivo and in vitro presumed potentially different mechanisms between crocin I and geniposide on T2DM. This research demonstrated that the mechanism of hypoglycemia in vivo from geniposide is not only one target of the α-glucosidase but provides the experimental background for crocin I and the geniposide deep processing and utilization.Keywords:gardenia;α-glucosidase;crocin I;geniposide;type 2 diabetes mellitus
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MOLECULES
·
2023
·Vol. 28
·期 5
·2250
·
IF 4.6
Zixuan Chen,Yuan-Yuan Zhao,Li Li,Ziqing Li,Shuwen Fu,Yihui Xu,Bi-Yuan Zheng,Meirong Ke,Xingshu Li,Jian-Dong Huang
Phthalocyanines are potentially promising photosensitizers (PSs) for photodynamic therapy (PDT), but the inherent defects such as aggregation-caused quenching effects and non-specific toxicity severely hinder their further application in PDT. Herein, we synthesized two zinc(II) phthalocyanines (PcSA and PcOA) monosubstituted with a sulphonate group in the alpha position with “O bridge” and “S bridge” as bonds and prepared a liposomal nanophotosensitizer ([email protected]) by thin-film hydration method to regulate the aggregation of PcSA in the aqueous solution and enhance its tumor targeting ability.[email protected]exhibited highly efficient production of superoxide radical (O2∙−) and singlet oxygen (1O2) in water under light irradiation, which were 2.6-fold and 15.4-fold higher than those of free PcSA, respectively. Furthermore,[email protected]was able to accumulate selectively in tumors after intravenous injection with the fluorescence intensity ratio of tumors to livers was 4.1:1. The significant tumor inhibition effects resulted in a 98% tumor inhibition rate after[email protected]was injected intravenously at an ultra-low[email protected]dose (0.8 nmol g−1PcSA) and light dose (30 J cm−2). Therefore, the liposomal[email protected]is a prospective nanophotosensitizer possessing hybrid type I and type II photoreactions with efficient photodynamic anticancer effects.Keywords:photodynamic therapy;phthalocyanine;liposome;fluorescence imaging;anticancer
✓ 已验证
DOI
PubMed
高影响因子
ELECTROCHIMICA ACTA
·
2018
·
IF 5.116
Chao Wang,Liuyi Hu,Kang Zhao,Anping Deng,Jianguo Li
Herein, a novel ultrasensitive competition-type electrochemiluminescent (ECL) immunosensor for detecting Sudan I was constructed using palladium/aurum core-shell nanocrystallines (Pd/Au CSNs) and CdSe@CdS QDs as signal bioprobe. The Pd/Au CSNs as outstanding nanocarrier equipped with superior performance like highly catalytic activity, good biocompatibility and large specific surface area, which enhanced ECL intensity significantly. The surface of electrode was coated with gold nanorods functionalized graphene oxide (GNRs/GO) nanocomposite film as the substrate, which provided an effective matrix to immobilize more coating antigen but also facilitated the electronic transmission to increase the ECL signal. The proposed immunoassay based on the synergistic effect of Pd/Au CSNs and GNRs/GO for determining Sudan I exhibited good stability, high sensitivity and wide linearity with a lower detection limit of 0.3 pg mL −1 (S/N = 3) and the wide range from 0.001 to 500 ng mL −1 . Furthermore, the developed immunosensor was successfully applied in determination of real samples with acceptable accuracy, and initiated a new route for detecting other small molecule in the future.
✓ 已验证
产品关联
DOI
高影响因子
Materials Research Express
·
2018
·Vol. 5
·期 9
·095310
·
IF 1.151
Kelong Chen,Tong Zhang,Yan Shi,Zhiyong Wang
The reversible complexation mediated polymerization (RCMP) of methyl methacrylate catalyzed by tetrabutylammonium iodide (BNI) was performed in toluene with an alkyl iodide initiator in situ formed. The influence of BNI amount, polymerization temperature, solvent, and initiator on the polymerization was studied. Results showed that the more organic catalyst, higher reaction temperature, highly polar solvent, and higher activity initiator led to shorter inhibition period and faster polymerization. More importantly, the mechanism for the shorter inhibition period and faster polymerization with BNI was proposed:
Poly(methyl methacrylate) with predetermined molar mass and relatively low Mw/Mn (determined by size exclusion chromatography, SEC) was successfully synthesized. Furthermore, the structure of resulting polymers was characterized using 1H NMR The living/controlled feature of the polymers was further demonstrated by the chain extension experiment. Attractive features of this procedure include commercially available catalyst, ease of operation, and efficiency.
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）