Cells
·
2022
·Vol. 11
·期 18
·2927
·
IF 7.666
Dewei He,Yanting Liu,Jie Li,Hefei Wang,Bojian Ye,Yuan He,Zhe Li,Xiyu Gao,Shoupeng Fu,Dianfeng Liu
Parkinson’s disease (PD) is a neurodegenerative disease in which neuronal apoptosis and associated inflammation are involved in its pathogenesis. However, there is still no specific treatment that can stop PD progression. Isoalantolactone (IAL) plays a role in many inflammation-related diseases. However, its effect and mechanism in PD remain unclear. In this study, results showed that IAL administration ameliorated 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine (MPTP)-induced PD-related pathological impairment and decreased motor activity in mice. Results from in vitro mechanistic studies showed that IAL regulated apoptosis-related proteins by activating the AKT/Nrf2 pathway, thereby suppressing the apoptosis of SN4741 cells induced by N-methyl-4-phenylpyridinium Iodide (MPP+). On the other hand, IAL inhibited LPS-induced release of pro-inflammatory mediators in BV2 cells by activating the AKT/Nrf2/HO-1 pathway and inhibiting the NF-κB pathway. In addition, IAL protected SN4741 from microglial activation-mediated neurotoxicity. Taken together, these results highlight the beneficial role of IAL as a novel therapy and potential PD drug due to its pharmacological profile.Keywords:isoalantolactone;PD;neuro-protection;neuro-inflammation;apoptosis
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ACS Applied Nano Materials
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2022
·
IF 6.14
Tao Xian,Hongqin Li,Xiaofeng Sun,Yashan Huo,Lijing Di,Chenyang Sun,Hua Yang
The In2O3 nanoparticles were homogeneously attached on the BiOBr nanoplate surface to obtain S-scheme In2O3/BiOBr heterojunction photocatalysts by a hydrothermal route. The purity, crystal structure, chemical state, morphology, light absorption property, and photogenerated charge behavior of composites were investigated by XRD, SEM, TEM, HRTEM, XPS, UV–vis DRS, PL, ESR, and electrochemical tests. The removal of dyes (acid orange 7 (AO7), acid orange 10 (AO10), and rhodamine B (RhB)) and Cr(VI) was employed to evaluate the photocatalytic performance of In2O3/BiOBr composites irradiated by simulated sunlight. The results indicate that the photocatalytic performance of BiOBr can be remarkably promoted after the decoration of In2O3 nanoparticles, and the best photocatalytic activity was achieved over an 8% In2O3/BiOBr sample. The 8% In2O3/BiOBr sample also indicates outstanding synergistic photocatalytic performance for the removal of the heavy metal ion/dye mixture (AO7/Cr(VI) and RhB/Cr(VI)). It is found that the decoration of In2O3 nanoparticles can accelerate the transfer and separation of photoinduced electrons and holes in BiOBr nanoplates. The energy band structure, work function, and Fermi level of BiOBr and In2O3 were computed through the density functional theory calculation. Based on the above investigation, the photocatalytic mechanism of the S-scheme In2O3/BiOBr composite was discussed.
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CHEMICAL ENGINEERING JOURNAL
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2022
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IF 16.744
Weijie Yang,Kailong Sun,Jun Wan,Yang-Ai Ma,Yu Wang,Lin Liu,Bicheng Zhu,Feng Fu
Solar-driven activation of molecular oxygen (O 2 ) offers an appealing strategy to realize aerobic oxidation catalysis at room temperature, while the efficiency of photocatalytic O 2 activation is severely limited by lacking O 2 adsorption sites and poor carrier utilization. Herein, an efficient Ni 2 P/Bi 3 O 4 Br-OVs heterojunction is firstly proposed to overcome the limitation by the dual-site design of oxygen vacancies (OVs) and on Ni 2 P cocatalyst. By the joint observations from spectroscopic measurements and theoretical simulations, the introduction of OVs and Ni 2 P on Bi 3 O 4 Br nanosheets can not only optimize the light absorption, facilitate the separation and transfer of photogenerated charge carrier through the S-scheme mechanism, but also provide active sites for effective adsorption and activation of oxygen molecules, thereby contributing to highly efficient generation of •O 2 − radicals. Benefiting from the more oxidative active species of •O 2 − and h + , the Ni 2 P/Bi 3 O 4 Br-OVs photocatalyst achieves near-unity conversion rate and selectivity in aerobic oxidation of sulfide to sulfoxide, and it also exhibits outstanding photoactivity in the aerobic degradation of phenolic pollutants under visible light. This study showcases a feasible O 2 activation approach by defect and heterojunction engineering, and provides a new perspective for designing high-performance photocatalysts in the field of aerobic oxidation catalysis.
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Advanced Materials Interfaces
·
2022
·Vol. 9
·期 26
·2201049
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IF 6.389
Yun Zhao,Qianqian Bai,Liqiang Chai,Xiaofei Dong,Jiangtao Chen,Jianbiao Chen,Yan Li,Xiuxun Han
Aiming at the current bottleneck of Cu 2 ZnSn(S,Se) 4 (CZTSSe) thin film solar cells, an experimental analysis of the performance and loss mechanism of CZTSSe thin film solar cells upon proton radiation exposure is presented. In order to deduce the important cell parameters, the environment of the cells is simulated by subjecting the devices to 200 keV proton irradiation with fluences from 1 × 10 10 to 1 × 10 17 cm -2 . It is found that the damage constants are sensitive to the elemental diffusion at heterojunction and Na redistribution in device. The incidence of the proton can lead to bandgap, tails fluctuations, and Urbach energy changes in the cells those directly impact defects and structural disorder in CZTSSe material thereby the device performance. The time-resolved photoluminescence results show that the carrier lifetime is also very sensitive to the distribution of interface elements, especially Na, Cd, and S. These findings may provide new ideas for solving the V OC deficit of CZTSSe solar cells. From this work, it can be also suggested that the CZTSSe thin film solar cells are robust to proton irradiation and have the potential for future space applications.
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CHEMICAL ENGINEERING JOURNAL
·
2021
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IF 13.273
Wenxiang Yang,Guozhi Ma,Yin Fu,Ke Peng,Hongli Yang,Xiaoqiang Zhan,Weiyou Yang,Lin Wang,Huilin Hou
The development of novel and efficient heterojunction photocatalysts is still a challenging issue for achieving highly efficient solar-to-chemical energy conversion. Herein, we report the construction of Ti 3 C 2 MXene@TiO 2 /CuInS 2 (M@T/CIS) integrated Schottky/step-scheme (S-scheme) heterojunction by two-step hydrothermal process for boosting photocatalytic hydrogen generation activity. The as-prepared M@T/CIS hybrid photocatalysts exhibit the synergistic effects for enhanced visible-light harvesting, improved charge transfer and increased active site for photocatalytic H 2 evolution. They deliver a H 2 evolution rate of 356.27 μmol g -1 h −1 , which is ∼ 69 and 636 times higher than those of M@T and CIS, respectively, representing their potential applications towards photocatalytic H 2 evolution.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2021
·
IF 8.128
Zhiliang Jin,Teng Li,Kai Wang,Xin Guo
Simple high-temperature calcination and hydrothermal methods were followed to synthesize CeO 2 and Mo-S, respectively. The efficient photocatalytic hydrogen evolution activity exhibited by the composite catalysts can be attributed to the edge active sites in Mo-S. The Mo-O bonds formed between CeO 2 and Mo-S could further accelerate the processes of separation and migration of electrons between the catalyst interfaces. The hybrid catalyst 10%-CeO 2 /Mo-S exhibiting the best hydrogen generation ability (4.3 mmol h −1 g −1 ) was obtained by optimizing the content of CeO 2 in CeO 2 /Mo-S. Analysis of the PL spectral profile and photocurrent response recorded for the system revealed that 10%-COMS exhibited excellent photogenerated carrier separation ability. Analysis of the LSV and EIS curves revealed that 10%-COMS exhibited the optimal hydrogen production potential. The charge migration resistance provided by the systems was lower than the charge migration resistance provided by CeO 2 and Mo-S. The synergism between the S-scheme heterojunctions and the Mo-O bonds helped accelerate the separation and migration of photo-induced carriers at the catalyst interfaces. The introduction of covalent bonds in the S-scheme heterojunctions and the results presented herein can potentially help develop a new method to realize photocatalytic hydrogen evolution.
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POLYMER DEGRADATION AND STABILITY
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2021
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IF 5.03
Chao Wan,Huajun Duan,Chenhao Zhang,Jianfan Cao,Jiahao Zou,Junjun Zhang,Huiru Ma
In order to obtain an efficient flame retardant without sacrificing mechanical properties and transparency of epoxy resin (EP), a P/N/S-containing flame retardant (STP) by combining 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) with Schiff base intermediate synthesized by the reaction of sulfathiazole and 2-thenaldehyde was successfully synthesized. The synthesis of STP was verified and the properties of modified EP were studied. The test results indicated that STP slowed down the degradation rate of EP. The glass transition temperature (T g ) of the flame-retardant epoxy resin (FREP) samples were well maintained and even improved after introducing a certain amount of STP. Furthermore, FREP with low phosphorus content exerted excellent flame retardant ability, EP/5%STP (phosphorus content: 0.27 wt%) obtained the V-0 rating of UL-94 test with the value of limiting oxygen index (LOI) 33.5%. In contrast with EP, the peak heat release rate (PHRR), total heat release (THR) and total smoke production (TSP) of EP/7.5%STP were respectively decreased by 33.31%, 26.04% and 28.75%. Mechanical performance tests show that STP improved the tensile and flexural strength of EP. It is worth mentioning that the EP modified with STP still maintains good transparency.
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EUROPEAN POLYMER JOURNAL
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2021
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IF 4.598
Jixian Li,Changjun Gong,Shuaikang Lv,Farong Huang
A series of poly(dimethylsilylene arylacetylene)s with different side alkoxy groups on the arylacetylene unit (named as PSA-(AO) resins), including methoxy (MO), ethoxy (EO), pentyloxy (PO), and decyloxy (DO), were synthesized from corresponding disubstituted diethynylbenzene and dichlorodimethylsilane. The processability, heat resistance and mechanical properties, and the effects of side alkoxy groups were investigated. The results show the processability of PSA-(AO) resins is improved, while the flexural properties and heat resistance of the relative cured resins decrease with the increase in the length of side alkoxy groups. The flexural strength and degradation temperature of 5% weight loss for the cured PSA-(EO) resin with side ethoxy groups reach 20.8 MPa and 415℃, respectively.
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Science China-Technological Sciences
·
2021
·Vol. 65
·期 2
·272-281
·
IF 3.572
Meng FanCheng,Xu Bin,Long Tao,Cheng Sheng,Li Yong,Zhang YongYi,Liu JieHua
Conductive carbon structure has been considered as a promising sulfur-hosting material as the cathode of lithium-sulfur batteries. However, the issue of polysulfide shuttling requires an additional component to help restrict and convert sulfur substances. Herein, in this work, hollow and porous carbon nanospheres (HCS) are synthesized by a template method and a high-temperature carbonization treatment. A thin layer of ZnS coating is then deposited on the HCS-based sulfur (ZnS@HCS/S) cathode with controlled thickness, and the overall electrochemical properties are systematically evaluated. Results show that with 30 nm-thick ZnS coating, the cathode reveals an improved capacity of 1411 mA h g −1 , and higher capacities from 0.2 to 3 C rate compared with bare HCS/S cathode. Moreover, the ZnS coating also enhances the cycling stability of ZnS@HCS/S cathode over 280 cycles at 0.5 C, with only 0.2% capacity decay per cycle. This work demonstrates potential applications for high-performance lithium-sulfur batteries.
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JOURNAL OF ALLOYS AND COMPOUNDS
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2021
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IF 5.316
Kristina Maliutina,Jiajia Huang,Tong Su,Jianglong Yu,Liangdong Fan
This work introduces nanostructured carbon-based composite with enriched CNTs and microstructural defects from pomelo peel biomass precursors through successive chemical pretreatment, heteroatom N, S dual-doping and transition metal oxide loading (Ta 2 O y ) and its application for electrochemical oxygen reduction reaction (ORR) at room temperature. During the microwave pyrolysis process, volatile N, S-containing species from trithiocyanuric acid reactant were trapped and doped into carbonaceous biomass precursor to achieving the rich-defect porous nanotubes and abundant cavity structure. The effect of biomass pretreatment on the textural and structural properties of biochar and formed CNTs were systematically investigated. The impacts of single doping (N) using melamine and dual-doping (N, S) with trithiocyanuric acid on the structural and electrochemical characteristics of biochar were evaluated. An optimized PP-NS-600-Ta-900 electrocatalyst displayed remarkable ORR activity with a half-wave potential of 0.82 V (vs. RHE), a limiting current density of −5.75 mA cm −2 and an electron transfer number of 3.85. The results offer a useful archetypical template to design and construct reliable CNTs enriched biomass-derived biochar for possible electrochemical energy and storage application, illustrating its viability for utilization as ORR electrocatalyst in potential applications, like fuel cells and metal-air batteries.
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AIP Advances
·
2021
·Vol. 11
·期 7
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IF 1.548
Lv Xiaogong,Zhu Chengjun,Yang Yanchun,Liu Ruijian,Fan Wenliang,Wang Yiming
In this work, Cu 2 ZnSnS 4 (CZTS) precursor films were deposited using a water-based solution approach. Subsequently, selenization was performed at different temperatures in the range of 480–610 °C to prepare Cu 2 ZnSn(S,Se) 4 (CZTSSe) absorber-layer films. The effects of the selenization temperature on the crystallinity, structure, morphology, and photoelectric properties of CZTSSe thin films, as well as the performance of solar cells constructed using these films, were systematically studied. The absorber-layer films selenized at different temperatures all formed pure-phase CZTSSe and had basically the same film thickness. It was found that application of an optimal selenization temperature can enhance the crystallinity, crystal grain size, and mobility and reduce the resistivity of CZTSSe films. Selenization at 550 °C resulted in the largest grain size (∼ μ m), the highest crystallinity, the highest mobility (4.29 cm 2 V −1 s −1 ), the lowest resistivity (3.13 × 10 2 Ω cm), the thinner fine-grained layer, a bandgap value of 1.21 eV, and a Cu-poor, Zn-rich elemental composition [Cu/(Zn + Sn) = 0.85 and Zn/Sn = 1.16]. The power-conversion efficiency was improved from 3.04% in a CZTSSe cell device with an absorber layer selenized at 480 °C to 4.69% in a film selenized at 550 °C. This was mainly due to the improvement of the crystallinity, crystal grain growth, and reduction of the fine-grained layer of the CZTSSe film. These results show that optimizing the selenization temperature is essential for enhancing the performance and the ultimate device efficiency of CZTSSe absorber layers prepared using a water-based solution approach.
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WATER RESEARCH
·
2021
·
IF 11.236
Jingxin Yang,Yujie Luo,Xianghui Fu,Zijun Dong,Chuan Wang,Hong Liu,Chengchun Jiang
Transition metal catalyzed sulfite auto-oxidation is a promising technology used in water and wastewater treatment for the elimination of contaminants. In the literature, this process has been reported to be efficient only in the presence of oxygen. However, in this study, we unexpectedly found that the degradation of diatrizoate (DTZ) by a system based on the combination of copper ion and sulfite (Cu(II)/S(IV)) reached over 95% under anaerobic conditions , but was considerably retarded under aerobic conditions at pH 7. Furthermore, it was found that Cu(I), generated from the cleavage of the CuSO 3 complex, was the main reactive species responsible for the degradation of DTZ by the Cu(II)/S(IV) system under anaerobic conditions. In fact, the absence of oxygen promoted the accumulation of Cu(I). The concomitant release of the iodide ion with the degradation of DTZ indicated that the anaerobic degradation of DTZ by the Cu(II)/S(IV) system mainly proceeded through the deiodination pathway, which was also confirmed by the detection of deiodinated products. The anaerobic degradation of DTZ was favored at higher initial concentrations of Cu(II) or sulfite in this system. Since the CuSO 3 complex, the precursor of Cu(I), was formed mainly at pH 7, the highest anaerobic degradation of DTZ was achieved at pH 7. An increase in reaction temperature considerably enhanced the degradation of DTZ by the Cu(II)/S(IV) system with an apparent activation energy of 119.4 kJ/mol. The presence of chloride, bicarbonate and humic acid slightly influenced the anaerobic degradation of DTZ. The experiments with real water samples also demonstrated the effectiveness of the degradation of DTZ by the Cu(II)/S(IV) system under anaerobic conditions.
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