Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 3
·122376
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IF 7.5
Ying Xue,Qing Liu,Yang Yv,Xiaonan Hao,Yue Wu,Shulin Sun
Wastewater treatment remains a critical global environmental challenge. In this study, zeolitic imidazolate framework-8 (ZIF-8) was first grown in situ on carboxylated carbon nanotubes (CNT-COOH), followed by coating with tannic acid (TA). The CNT-COOH@ZIF-8@TA composite was successfully synthesized. Subsequently, a series of polyvinylidene fluoride (PVDF)/CNT-COOH@ZIF-8@TA (PZC) separation membranes were fabricated by the non-solvent-induced phase separation (NIPS) method. Separation tests demonstrated the high removal efficiencies (>99%) of PZC membranes for methylene blue (MeB) and auramine O (AO) dyes, along with effective retention of corn oil and pump oil emulsions. Furthermore, the engineered PZC membranes exhibited significant adsorption capacity for aqueous dyes, achieving removal rates exceeding 98% for both MeB and AO. The adsorption characteristics and underlying mechanisms were elucidated through kinetic, isothermal, and intra-particle diffusion modeling. Additionally, the PZC membranes demonstrated catalytic activity towards MeB degradation, and the PZC4 membrane achieved a degradation efficiency of 88.3%. Moreover, to enhance membrane longevity, membrane regeneration was achieved through photocatalytic cleaning under UV irradiation, offering an alternative to conventional cleaning methods. This study systematically analyzed the chemical structure, surface morphology, hydrophilicity, and charge properties of the material through multiple characterization techniques, including Fourier Transform Infrared Spectroscopy (FTIR), X-ray Photoelectron Spectroscopy (XPS), Scanning Electron Microscopy (SEM), contact angle measurement, and Zeta potential analysis. The membrane's wastewater purification capability was comprehensively evaluated by combining filtration performance, adsorption experiments, and photocatalytic testing. The designed separation membranes offer promising solutions for the post-treatment of oil spills and the remediation of dye-contaminated wastewater.
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CHEMICAL ENGINEERING JOURNAL
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2026
·
IF 12.5
Hui Xu,Yuhang Zhong,Dingke Wang,Ran Sun,Yujie Tan,Xingang Liu,Jianyuan Hou,Yuan Yuan,Ximan Dong,Renxi Zhang
Cu/Z-700 enables plasma-driven H₂ evolution from simulated seawater vapor. • Dynamic Cu redox cycling acts as an electron relay during plasma catalysis. • Cu clusters, Cu N sites, and pyridinic N perform differentiated functions. • An H₂ rate of 1.33 mL min −1 is achieved with >95% activity after five cycles. How different active sites cooperate under non-thermal plasma (NTP) conditions is still poorly understood. Here, Cu-doped ZIF-8-derived carbon carbonized at 700 °C (Cu/Z-700) is shown to host three distinct active centers: metallic Cu clusters, Cu–N coordinated (Cu–NC) moieties and pyridinic N (Py-N) sites. Cu K-edge X-ray absorption spectroscopy reveals that ~80% of Cu exists as metallic clusters and ~ 20% as isolated Cu δ+ –Nₓ sites. Density functional theory (DFT) calculations suggest a functional division among the three sites: Cu clusters show the strongest Cu–OH binding and the most favorable reaction free energies, Cu–NC sites favor intermediate conversion and product desorption, and Py-N sites promote water adsorption. In a dielectric barrier discharge (DBD), Cu/Z-700 delivers a H₂ production rate of 1.33 mL min −1 from water vapor generated from simulated seawater at a residence time of 3 s, an 11-fold enhancement over plasma alone, with 93.6% activity retention over 20 cycles. Gas-phase product analysis shows that more than 97% of the H₂ originates from water splitting. The results clarify the nature of the active sites in Cu/ZIF-8-derived carbon and their contribution to plasma-catalytic water splitting. Download: Download high-res image (169KB) Download: Download full-size image
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INTERNATIONAL JOURNAL OF PHARMACEUTICS
·
2026
·
IF 6
Huan Zhou,Ning Zhang,Chaoyue Sun,Min Feng,Ting Yang,Yonghong Liang,Chang Peng,Zhao Fu,Haiyan Zhang
Ulcerative colitis (UC) demands lifelong therapy, yet current regimens require daily high-dose administration that drives poor adherence and cumulative toxicity. Although α-terpineol (αTL) shows therapeutic efficacy in colitis, its oral application is limited by poor oral bioavailability and a lack of colon specificity. Rather than relying on sophisticated surface engineering, we encapsulated αTL within zeolitic imidazolate framework-8 (ZIF-8) during co-nucleation. This unmodified design permitted partial gastric release (∼46%) in gastric fluid and minimal release in intestinal fluid, with the remaining cargo subsequently released in the acidic environment of the inflamed colon. Oral administration of αTL@ZIF-8 resulted in colonic retention exceeding 24 h in DSS-induced colitis mice. Leveraging this colonic accumulation, an every-other-day regimen at 10 mg kg −1 achieved efficacy comparable to daily free αTL at 100 mg kg −1 or cyclosporine A at 60 mg kg −1 . Mechanistically, αTL@ZIF-8 restored Claudin-1 and ZO-1 expression, enriched butyrate-producing genera and elevated butyrate levels, and uniquely modulated glutathione synthesis-related pathways. Safety evaluation in healthy mice showed no overt toxicity under this regimen. This formulation reduces premature drug exposure in the upper gastrointestinal tract and allows more αTL to reach the acidic environment of the inflamed colon. These features enable a low-dose, every-other-day oral regimen that decouples therapeutic efficacy from dosing frequency, positioning it as a promising candidate for long-term UC management. Scheme 1. Schematic diagram of the preparation of orally administered αTL@ZIF-8 and its alleviation effects on colitis mice. Download: Download high-res image (194KB) Download: Download full-size image
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COMPOSITES COMMUNICATIONS
·
2026
·
IF 8.6
Xi Chen,Yu Zhang,Binggang Liu,Siyuan Dong,Xinbo Dong,Xigao Jian,Cheng Liu
A “grape cluster”-like multiscale hybrid structure (CNT@ZIF-8) was successfully constructed by in-situ growth of ZIF-8 nanoparticles on CNT surfaces. • Molecular dynamics simulations revealed the interaction mechanism between CNT-COOH and ZIF-8 at the molecular level. • The CNT@ZIF-8 hybrids were uniformly anchored onto electrospun fibers via a combined electrospinning–electrospray process to achieve multiscale reinforcement. • G IC ,ini and G IC ,prop increased by 59% and 50% respectively, G IIC rose by 192%; and in-plane properties were significantly improved. In fiber-reinforced high-performance thermoplastic composites, the surface inertness of carbon nanotubes (CNT) limits interfacial bonding with the polymer matrix, significantly reducing their reinforcing and toughening efficiency. To address this, we propose a surface modification strategy for high-temperature processing: in-situ growth of ZIF-8 nanoparticles on CNT surfaces to construct a “grape-like” multiscale hybrid (CNT@ZIF-8). Using combined electrospinning–electrospray, CNT@ZIF-8 is uniformly loaded onto electrospun fibers, and the resulting mats are introduced into the interlaminar region of CF/PPESK composites, achieving synergistic strength and toughness enhancement. Compared to the unmodified composite, Mode I interlaminar fracture toughness (initiation and propagation) increases by 59% and 50%, respectively; Mode II toughness improves by 192%; flexural strength and interlaminar shear strength increase by 36% and 27%, respectively. The enhanced performance is attributed to two factors: (1) CNT@ZIF-8 anchoring on electrospun fibers improves fiber–matrix interfacial bonding; (2) the nanoscale rough structure of ZIF-8 on CNT enhances mechanical interlocking with the resin matrix. Molecular dynamics simulations reveal strong hydrogen bonding between CNT and the ZIF-8 precursor (2-methylimidazole). During loading, the “grape-like” hierarchical structure suppresses CNT debonding and sliding, promoting energy dissipation via enhanced interfacial friction and multi-path crack propagation, thereby greatly increasing energy absorption during fiber pull-out. This work provides a new strategy and theoretical basis for surface modification of CNT in high-temperature resistant thermoplastic matrices.
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MICROCHEMICAL JOURNAL
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2026
·
IF 5.2
Wenxia Chen,Rui Yuan,Xianlong Lu,Jing Qi,Xiaomin Zuo,Rui Yang
A 3D μPAD featuring physical isolation has been designed for crosstalk-free triplex detection. • A ZIF-8/CuFe 2 O 4 nanozyme, which exhibits broad-spectrum POD-like activity and generates three distinct color signals, has been synthesized. • A low-cost POCT platform that integrates functional materials, devices, and intelligent readout for GSH, AA, and DA has been developed. This work addresses the challenge of synchronous and rapid on-site detection of multiple metabolic small molecules in serum, and has constructed a point-of-care testing (POCT) platform based on broad-spectrum catalytic nanoenzyme and anti-interference three-dimensional (3D) paper chip. The ZIF-8/CuFe 2 O 4 composite nanoenzyme, prepared by a simple method, utilizes its interface synergy effect and exhibits excellent broad-spectrum peroxidase-like (POD-like) activity, capable of simultaneously and efficiently catalyzing the production of three-color contrasting chromogenic signals with 3,3′,5,5′-tetramethylbenzidine (TMB), 4-aminoantipyrine (4-AAP)/phenol, and o -phenylenediamine (OPD). On this basis, a 3D microfluidic paper-based analytical device (μPAD) with vertically isolated flow channels is constructed, which fundamentally eliminates signal crosstalk in multi-channel detection from the physical architecture level. During the detection, the target substances glutathione (GSH), ascorbic acid (AA), and dopamine (DA) quantitatively regulate the chromogenic reaction through competitive inhibition mechanisms. Combined with smartphone imaging and image analysis, synchronous and rapid quantification of the three substances can be achieved. The limit of detection (LOD) of this platform for GSH, AA, and DA is 0.072 μM, 0.44 μM, and 0.29 μM, respectively. Additionally, it shows a good recovery rate and reliability in diluted human serum samples. The integrated strategy of “functional materials–device design–intelligent reading” proposed in this work offers a new solution that is low-cost, easy-to-operate, and resistant to interference for on-site immediate detection of multiple indicators. Download: Download high-res image (131KB) Download: Download full-size image
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
·
2026
·
IF 9.2
Shanshan Li,Qingrong Zheng
A convenient method that can accurately calculate adsorption equilibrium data of hydrogen on MOFs is crucial to practical applications. The storage density of hydrogen on a target ship was employed to screen suitable adsorbents from ZIFs via GCMC simulations conducted to quantitatively evaluate the influences from the main textural parameters. ZIF-8 was selected to measure adsorption isotherms of nitrogen and hydrogen. A modified adsorption model was developed by comparing the accuracies of two Langmuirian equations. It shows that adsorption capacities of hydrogen on the ZIFs almost linearly increase in the specific surface areas and micro-pore volumes, and Tóth equation had higher prediction accuracies. By introducing the main textural parameters as the influencing factor, the adsorption model for ZIF-8 only resulted in a mean relative error about 0.12%. It suggests that the methodology presented is worth investigating for analyzing hydrogen adsorption on other categories of MOFs.
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 3
·122841
·
IF 7.5
Mian Zhu,Chao Lyu,Xieding Sun,Xiaochuan Yang,Jingxian Liu
To develop high-efficiency carbon dioxide (CO 2 ) adsorbents featuring low-pollution and low-energy-consumption preparation, gel bead precursors were first fabricated via gelation of nanocellulose, polyvinyl alcohol (PVA), and 2-methylimidazole. A nitrogen-doped precursor derived from hydrothermal recrystallization of melamine and dextrin was uniformly incorporated into the gel matrix to construct a nitrogen-enriched system. Subsequently, ZIF-8 was grown in situ within the composite beads through immersion in a zinc ion solution, yielding a biomass-polymer@ZIF-8 support after drying, which was then carbonized under N 2 to produce nitrogen-doped porous carbons. Based on static CO 2 adsorption evaluations across 15 sample sets at 0 ℃ and 25 ℃, 800 °C was identified as the optimal carbonization temperature. The sample CZN-II-800, with 4.31% external nitrogen doping in the precursor, exhibited absolute CO 2 adsorption capacities of 3.39 mmol/g at 0 ℃ and 3.08 mmol/g at 298 K (1 bar), which was 66.5% higher than that of its nitrogen-free counterpart CZ-800. Additionally, it displayed a CO 2 /N 2 selectivity coefficient of 8.9 under dynamic competitive adsorption conditions at 1 bar and 298 K. This work therefore establishes a scalable hybrid route integrating biomass materials with ZIFs to design high-performance adsorbents for efficient CO 2 capture from flue gases.
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Frontiers in Nutrition
·
2026
·
IF 5.5
Yang Chong,Fengsong Nie,Xiang Huang,Lingli Wang,Lingling Zhu,Shu Zhang,Junjun Yu,Yang Wang
IntroductionThe development of sensing interfaces that can simultaneously achieve efficient enrichment of targets and enhanced electron conduction is the key to improving the performance of phenolics detection in foodMethodsIn this paper, a novel electrochemical sensing platform consisting of an aminated zeolite imidazolium ester backbone material (ZIF-8-NH2) composited with sodium oxidized alginate (OSA)/carboxymethyl chitosan (CMCS) dynamic hydrogel (denoted as OC hydrogel) was successfully constructed. The platform exploits the mild Schiff base reaction between OSA and CMCS to construct a three-dimensional dynamic hydrogel substrate without an external cross-linking agent. On this basis, the combination of ZIF-8-NH2 and OC hydrogel was introduced. The amino groups on the surface of ZF-8-NH2 and the aldehyde groups of OSA are utilized to form covalent nano-crosslinking points, simultaneously exerting their electrocatalytic activity and pre-enrichment effect.ResultsElectrochemical studies demonstrated that the composite interface significantly accelerated electron transfer kinetics. The constructed sensor demonstrates exceptional analytical performance for hydroquinone. The detection limit is as low as the nanomolar level (16.7 nM), and the linear range extends up to four orders of magnitude (0.05 to 1800 μM). Furthermore, the sensor demonstrated its efficacy in the rapid analysis of a wide range of real samples (tap water, drinking water, beverages, and vegetable juices), with recoveries ranging from 97.4 to 103.6%.DiscussionThe observed performance is attributed to the multiple synergistic effects of the ZIF-8-NH2/OC hydrogel interface. The covalent connection between ZIF-8-NH2 and the OSA/CMCS hydrogel prevents nanomaterial detachment, ensuring interface stability. Meanwhile, ZIF-8-NH₂ reduces the overpotential for hydroquinone electrochemical oxidation and achieves significant signal amplification through pre-enrichment of target molecules. These features substantiate the reliability of the sensor in practical applications, offering an innovative solution for the detection of harmful substances in food.
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Biotechnology Journal
·
2026
·Vol. 21
·期 3
·e70202
·
IF 3.7
Gaowei Hu,Jingyi Yang,Yumeng Li,Xi Luo,Longfei Yin,Wenji Wang,Yongqian Fu
Zeolitic imidazolate framework-8 (ZIF-8) has limitations in vaccine delivery, including poor targeting and rapid clearance. The outer membrane phosphoporin pore protein (PhoE) has been validated as a promising antigen against Klebsiella pneumoniae . We developed a mannose (M)-functionalized ZIF-8 nanoparticle (PhoE@M-ZIF-8) via polyethylene glycol (PEG) conjugation and mannose conjugation to enable targeted delivery to antigen-presenting cells (APCs). PhoE@M-ZIF-8 exhibited pH-responsive antigen release and was internalized via mannose receptor-mediated macropinocytosis, promoting dendritic cell maturation (CD11c + CD86 + upregulation) and inducing a balanced T helper type 1/type 2 (Th1/Th2) immune response. In vivo, PhoE@M-ZIF-8 achieved potent protection against lethal Klebsiella pneumoniae challenge with only two immunizations, showing high survival rates and favorable biosafety. This work presents a versatile APC-targeting platform for effective subunit vaccine development.
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PubMed
高影响因子
Gels
·
2025
·Vol. 11
·期 10
·813
·
IF 5.3
Bingbing Chen,Mengqi Hao,Hao Cui,Rui Zeng,Hang Ma,Anying Long,Xuegang Li
Periodontitis is a chronic oral inflammatory disease whose treatment is often hindered by poor drug retention, prolonged therapeutic regimens, and the rise of antibiotic resistance. In this study, we developed a Hydrogel@ZIF-8@metronidazole (Hydrogel@ZIF-8@MNZ) nanocomposite dressing for targeted, sustained, and in situ antimicrobial therapy. This system integrates ZIF-8, a pH-responsive metal–organic framework, with the antimicrobial agent metronidazole (MNZ), encapsulated within a crosslinked hydrogel matrix to enhance stability and retention in the oral environment. Drug release studies demonstrated that MNZ release was significantly accelerated under acidic conditions (pH 5.0), mimicking the periodontal microenvironment. The Hydrogel@ZIF-8 composite achieved a maximum MNZ adsorption capacity of 132.45 mg·g −1 , with a spontaneous and exothermic uptake process best described by a pseudo-second-order kinetic model, suggesting chemisorption as the dominant mechanism. The nanoplatform exhibited strong pH-responsive behavior, with enhanced drug release under acidic conditions and potent dose-dependent bactericidal activity against Fusobacterium nucleatum ( Fn ). At the highest tested concentration, bacterial survival was reduced to approximately 30%, with extensive membrane disruption observed through live/dead fluorescence microscopy. In summary, the stimuli-responsive Hydrogel@ZIF-8@MNZ nanocomposite offers an intelligent and effective therapeutic strategy for periodontitis. By tailoring its action to the disease microenvironment, this platform enables sustained and localized antibacterial therapy, addressing major challenges in the treatment of chronic oral infections.
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PubMed
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INORGANIC CHEMISTRY COMMUNICATIONS
·
2025
·
IF 5.4
Xing Wei,Yaling Ye,Wanling Cai,Zuliang Chen
Antibiotics like doxorubicin hydrochloride (DOX) are widely used in medicine, but their environmental residues pose risks to human health and ecosystems. This study optimized the synthesis of C-Fe₃O₄@ZIF-8 composites using response surface methodology (RSM) to enhance DOX release efficiency, thereby mitigating environmental antibiotic contamination. Under optimized conditions (37 °C, pH 5.0), the C-Fe₃O₄@ZIF-8 composite achieved a significant increase in cumulative DOX release, from 40.8% to 61.1%. The pH-responsive release further validated the optimization strategy. Characterization via scanning electron microscopy (SEM) and X-ray diffraction (XRD) revealed a structural transformation from rhombic dodecahedral crystals to more stable spherical particles with enhanced crystallinity. Fourier-transform infrared spectroscopy (FTIR) and X-ray photoelectron spectroscopy (XPS) confirmed an increase in surface-active sites and oxygen-containing functional groups, contributing to improved drug release efficiency. These findings provide valuable insights into optimizing C-Fe₃O₄@ZIF-8 for drug delivery, advancing environmentally friendly antibiotic management strategies.
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JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY
·
2026
·
IF 2.5
Lin Shiji,Chen Yuantao,Zhang Wei,Shao Chaoli,Mao Haibo,Zhou Xiaohang
Radioactive iodine from nuclear accidents like Fukushima necessitates efficient wastewater treatment technologies. Current adsorbents are hampered by challenging recovery and limited reusability. Herein, we synthesize a magnetic composite, GS@Fe3O4@ZIF-8, by anchoring ZIF-8 to magnetized Galdieria sulphuraria(GS), allowing for sub-one-minute magnetic separation. This adsorbent achieves a high iodine adsorption capacity of 1712.08 mg/g at pH 5, outperforming most MOF-based benchmarks. Characterization (XRD, SEM, FT-IR, XPS, EDS) verified its structure. Adsorption studies determined the optimal conditions (pH 5) and demonstrated robust performance across varied concentrations, temperatures, and times. The material also exhibits superior selectivity and stability, retaining 83% efficiency over three cycles. Our findings highlight GS@Fe3O4@ZIF-8 as a sustainable and recyclable material for radioactive iodine capture.
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