RSC Advances
·
2020
·Vol. 10
·期 50
·29668-29674
·
IF 3.119
Shuangxia Wu,Fengjie Geng,Suqin He,Wentao Liu,Hao Liu,Miaoming Huang,Chengshen Zhu
To increase the bioavailability and water solubility of hydrophobic medicine, an amphiphilic block copolymer, polycaprolactone-block-polyhydroxyethyl acrylamide (PCL-b-PHEAA), was synthesized. The copolymer can self-assemble into micelles by dialysis. The micelles were characterized by the Tyndall effect, static drop method, fluorescence spectrometry, dynamic light scattering, scanning electron microscopy and transmission electron microscopy. Ibuprofen was encapsulated inside the micelles by dialysis as a model medicine. The results show that the amphiphilic copolymer forms a uniform micelle system, with spherical micelles dispersed well in solution which have a low critical micelle concentration. In addition, the system shows good amphipathic behavior. Average particle size of a micelle is 104 nm, which increases a lot after drug loading and standing for half a month. In the first few hours, the cumulative release of the drug increases gradually; the rate of increase in the first ten hours is faster, then reaching a plateau which tends to be flat finally. It is similar under two different pH conditions. This biocompatible, biodegradable amphiphilic block copolymer has potential applications in the biomedical field.
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高影响因子
ELECTROCHIMICA ACTA
·
2017
·
IF 4.798
Binghu Wang,Yong Qin,Wensheng Tan,Yongxin Tao,Yong Kong
3D N-doped mesoporous graphene (N-3DMG) is fabricated by using amidated graphene oxide (AMGO) as the precursor. The amidation of graphene oxide not only avoids restacking of graphene sheets when AMGO is reduced to amidated graphene (AMG), but also provides nitrogen source for the N-3DMG. When the N-3DMG is used for supercapacitor, it exhibits a considerable specific capacitance, high rate capability and excellent cyclic stability. The 3D mesoporous structure and the high N-doping content are believed to be responsible for the high capacitive performances.
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POLYMER SCIENCE SERIES B
·
2022
·Vol. 64
·期 5
·644-650
·
IF 1.023
Zheng X. C.,Wu C. L.,Xiong J.,Lei H.
Abstract Poly( N -isopropylacrylamide) was grafted onto the surface of polypropylene by a two-step surface photo-grafting method using benzophenone as a photosensitizer to impart surface temperature sensitivity to polypropylene. The structure of graft-copolymer was characterized by infrared spectroscopy and scanning electron microscopy. Its temperature sensitivity was investigated by modulated differential scanning calorimetry and surface water contact angle determination. The effects of initiator concentration, photoreduction time, monomer concentration and light exposure time on grafting rate are discussed. The results showed that graft-copolymer is temperature-sensitive hydrophilic/hydrophobic, and its low critical solubility temperature is around 33°C. The grafting rate could be increased by increasing the initiator concentration, monomer concentration, extending the photoreduction time and irradiation time; and the grafting rate could be controlled by adjusting these four factors.
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Frontiers of Optoelectronics
·
2017
·Vol. 10
·期 2
·132-137
·
IF 0
Jiang Chen,Zhan Honglei,Zhao Kun,Fu Cheng
The terahertz (THz) time-domain spectroscopy technique was used to characterize the cooling process of solid n -alkanes. The THz waveforms of n -octadecane, n -nonadecane, n -eicosane, n -heneicosane, n -docosane, and n -pentacosane were obtained with the cooling time using the aforementioned noncontact optical method. The peak values of the THz signal were found to be related to the cooling temperature of n -alkanes. The THz wave was sensitive to the size and structure of particles in the liquid; therefore, the crystallization process of n -alkanes was monitored. An empirical equation based on signal attenuation was proposed to quantitatively distinguish the content change of structural order in the samples. Results present a new noncontact optical approach for characterizing wax crystallization via THz time-domain spectroscopy.
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Polymers
·
2021
·Vol. 13
·期 11
·1754
·
IF 4.329
Huishi Pi,Weiping Li,Zhiwei Shi,Haining Chen,Xiaoyu Jiang
N-vinylpyrrolidone (NVP) has a large molecular structure, so it is difficult to diffuse during holographic recording, especially at low spatial frequencies. We used glycerol to promote the diffusion of NVP, and successfully improved the holographic performance of the photopolymer at low spatial frequencies. As the concentration of glycerol increases, the holographic performance first increases and then remains stable. The optimal concentration of glycerol is 0.21 mol/L. At this concentration, the maximum diffraction efficiency of the photopolymer is 84%, the refractive index modulation is 1.95 × 10−3, and the photosensitive sensitivity is 7.91 × 10−4cm2/mJ. Compared with the control group, the maximum diffraction efficiency, maximum refractive index modulation and photosensitivity at low spatial frequencies (800 lp/mm) have increased by 11.19 times, 4.69 times and 1.71 times, respectively. Using the optimized photopolymer for transmission holographic recording and reproduction, we have obtained a clear and bright transmission hologram. The photopolymer modified with glycerol is expected to be applied to the fields of holography, diffractive optics, and so on.Keywords:transmission holography;photopolymer;polymerization rate;diffusion rate;diffraction efficiency
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ELECTROCHIMICA ACTA
·
2021
·
IF 6.901
Shuyue Yang,Dongmei Zhang,Jie Xu,Zongping Zhang,Shibing Ni
High theoretical capacity and safety performance endow Li 3 VO 4 with great promising as anode material for Li-ion batteries. However, approaches and inner mechanisms to advance the performance of Li 3 VO 4 are limited. Herein, we demonstrate for the first time, continuously-high pseudocapacitive charge storage triggered by N doped MXene in a Li 3 VO 4 -based electrode, resulting in excellent comprehensive electrochemical performance. The hybrid electrode delivers high discharge capacity of 515.2 mAh g −1 after 500 cycles at 0.1 A g −1 . After periodic rate performance test from 0.1 to 2.0 A g −1 for 410 cycles, the capacity of the hybrid electrode can be fully recovered. Followed by additional 1000 cycles at 0.5 A g −1 , the hybrid electrode still delivers high discharge capacity of 457.6 mAh g −1 . The robust capacitive charge storage induced by N doped MXene and the remarkable comprehensive electrochemical performance are referential for the design of high performance Li 3 VO 4 -based anode material, and the facile approach is beneficial for mass production toward practical application. Graphical abstract Download : Download high-res image (210KB) Download : Download full-size image N doped MXene induced robust pseudocapacitive charge storage in a Li 3 VO 4 electrode is firstly demonstrated responsible for the excellent comprehensive electrochemical performance.
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MEDICINAL CHEMISTRY RESEARCH
·
2022
·Vol. 31
·期 6
·936-948
·
IF 2.351
Hu Shijia,Li Yunqi,Kan Weiqiong,Ding Tingting,Gu Haijun,Zhang Ting,Yi Zhengfang,Chen Yihua
A series of diphenyl- N -heteroaromatic compounds were designed, synthesized, and evaluated for anticancer efficacies (antimigration and antiproliferation) against human cancer cell lines. The favorable 2 H -1,2,3-triazole compound 4a was optimized, leading to the discovery of compounds 4b and 4c with more potent antimigratory and antiproliferative activities. The transwell assay showed that compounds 4b and 4c dose-independently inhibited the migration of the two cancer cell lines (human breast cancer cell line MDA-MB-231 and pancreatic cancer cell line PANC1) with the low IC 50 values of 0.24 and 0.47 µM, respectively. The sulforhodamine-B (SRB) assay showed that compounds 4b and 4c inhibited the proliferation of PANC1 cells with the IC 50 values 0.86 µM and 1.41 µM, respectively. These results indicate that compounds 4b and 4c with 1,2,3-triazole scaffold may be further developed as potent anticancer agents in the future.
A series of novel diphenyl- N -heteroaromatics based on our previous published research work were synthesized and evaluated for their antimigration efficacies against MDA-MB-231 and PANC1 human cancer cell lines. Compound 4c dose-independently inhibited the migration of the two cancer cell lines (MDA-MB-231 and PANC1) with low IC 50 values 0.32 µM and 0.24 µM respectively.
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RSC Advances
·
2016
·Vol. 6
·期 20
·16177-16182
·
IF 3.289
Jingjie Su,Zhaodong Li,Yongquan Zhang,Yingjin Wei,Xudong Wang
TiO2-B is a metastable phase of titania with an interesting crystal structure and electrochemical properties. N-Doped and Cu-doped TiO2-B nanowires (NWs) were synthesized by hydrothermal and microwave-assisted hydrothermal methods, respectively. All the NWs are single crystal with the same crystal orientation regardless of the synthesis method and doping situation. The doped NWs together with their corresponding pristine NWs were fabricated into a photoelectrochemical (PEC) anode for water oxidation and their photoactivity performances were studied and compared under different illumination wavelength ranges. The Cu-doped TiO2-B NWs exhibited a significantly higher photocurrent density than all the other samples under direct Xe lamp illumination; while their performance rapidly dropped below the hydrothermal NWs when the UV illumination was cut off. On the contrary, N-doped TiO2-B NWs exhibited significantly enhanced photoactivity particularly in the visible light range. X-ray photoelectron spectroscopy revealed that N-doping could narrow the electronic bandgap of TiO2, while the Cu-doping had little impact on the bandgap but rather improved the electrical conductivity. This research provides a new insight into elemental and phase control of TiO2-based solar energy harvesters.
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TEXTILE RESEARCH JOURNAL
·
2016
·
IF 1.299
Jindan Wu,Yuelin Jiang,Ju He,Sufang Zhao,Guoqiang Cai,Jiping Wang
Thermo-responsive textile is newly developed and has wide application potentials in various fields. As the most commonly used textile, polyester has advantages in easy care, great durability and low cost. Since it has no reactive groups in fiber for surface functionalization, amino groups were generated by aminolysis in this study. By applying alkali deweighting during the aminolysis process, more -NH2 was produced. Poly(N-isopropylacrylamide) (PNIPAAm) was then grafted onto the surface via surface-initiated atom transfer radical polymerization. Infrared and X-ray photoelectron scanning measurements confirmed the success of PNIPAAm grafting. The thermo-switchable surface wettability was then explored by the test of surface wettability and fiber swelling–deswelling behavior. When the temperature rose, the surface switched from hydrophilic to hydrophobic as the contact angle transited from 0° to 120° reversely. This work established a feasible way and provided a new insight for preparing thermo-responsive polyester fabrics with smart cleaning and smart comfort properties.
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Nanomedicine
·
2017
·
IF 4.727
Ye Cao,Dejun Li,Mengli Zhao,Huanhuan Gong,Rongxin Wan,Hanqing Gu
Aim: The aim of the present research was to synthesize N+ implanted 3D self-assembly graphene (N+/3D-SGHs) to overcome the weaknesses of graphene (small sizes and poor hydrophilicity) in tissue engineering scaffolds. Materials & methods: N+/3D-SGHs was achieved by ion implantation on one-step hydrothermal synthesized 3D self-assembly graphene (3D-SGHs), and N+/3D-SGHs with different doses of nitrogen ions (1 × 1016 ions/cm2, 1 × 1018 ions/cm2 and 1 × 1020 ions/cm2), which adjusted by nitrogen ion beam intensity. Results: N+/3D-SGHs, as scaffolds, provide stereo space and hydrophilic groups for mouse-fibroblast cells (L929) growth and proliferation. Notably, N+/3D-SGHs with the N+ injected quantity of 1 × 1020 ions/cm2 displayed the highest protein-adhesion strength, cell viability and proliferation, which supported its good cytocompatibility. Conclusion: This study demonstrated N+/3D-SGHs as a promising and effective tissue scaffold that might have applications in biomedicine.
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CHINESE JOURNAL OF CHEMICAL ENGINEERING
·
2021
·
IF 3.171
Qinggele Borjihan,Quanfu Yao,Huihui Qu,Haixia Wu,Ying Liu,Alideertu Dong
Antibiotic-resistant bacteria contamination in environments imposes great threats to human life health. This research aims to develop novel targeted antibacterial biochars for achieving high selectivity to kill pathogenic Escherichia coli ( E. coli ). The glycopolymer N -halamine-modified biochars ( i.e ., BCPMA-Cl) were synthesized by the modification of biochars with poly[2-(methacrylamido) glucopyranose- co -acrylamide] (P(MAG- co -AM), followed by chlorination treatment. Based on the results of FTIR, turbidity, XPS, and UV–vis, BCPMA-Cl was successfully synthesized and demonstrated to be able to eliminate Staphylococcus aureus ( S. aureus ) and E. coli. Especially, BCPMA-Cl possessed extremely potent to specific-killing 10 4 CFU∙ml −1 of E. coli with lower hemolytic activity (<5%). Additionally, the antibacterial mechanisms of BCPMA-Cl against bacteria were contact-killing and release-killing contributed by active chlorine ( i.e ., Cl + ). Therefore, this work provided a cost-effective and facile approach for preparation of functional biochars used for bacteria-specific therapeutic applications via livestock pollutants as well as showing a promising strategy to avoid bacterial resistance.
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SURFACE & COATINGS TECHNOLOGY
·
2022
·
IF 4.865
Mingliang Dong,Weijin Qian,Xingzhen Liu,Yawei Chen,Weijun Huang,Changkun Dong
N-doped Carbon nanotube (NCNT)-Pd nanocomposites were fabricated by two convenient methods to make thermo-cell (TEC) electrodes. NCNTs were first synthesized on the alloy substrate (AS) using electrophoretic deposition technique, then Pd nanoparticles were coated on the surface of NCNT by magnetron sputtering. The TEC electrodes were characterized by scanning electron microscopy, transmission electron microscopy, X-ray diffraction, Raman spectroscopy, and X-ray photoelectron spectroscopy. The TEC performances of the NCNT-Pd nanocomposite electrode were enhanced significantly compared to those of the NCNT electrode with the current density of 58.4 A·m −2 and the power density of 1.08 W·m −2 , due to better catalytic activity and more activation sites. Meanwhile, the relative conversion efficiency of 1.04% was reached. This investigation suggests that the construction of the NCNT-Pd nanocomposite electrode could effectively improve the TEC performances of NCNT electrodes, very promising for the heat energy harvesting applications.
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