CATALYSIS LETTERS
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2026
·Vol. 156
·期 6
·169
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IF 2.5
Wang Mei,Wu Tong,Song Xianghai,Bu Quan,Zhou Bingliang
This study presents a high-performance cobalt catalyst supported on microwave-pyrolyzed biochar (Co/MPC) for efficient peroxymonosulfate (PMS) activation to degrade atrazine (ATZ). The microwave-assisted pyrolysis (MWP) technique yielded biochar (MPC) with superior textural properties—specifically, a significantly higher specific surface area (214.18 m 2 /g) and pore volume (0.46 cm 3 /g)—compared to conventionally pyrolyzed biochar (BC). This enhanced porous structure facilitated the uniform dispersion of ~5 nm cobalt nanoparticles, resulting in the highly active Co/MPC catalyst. The Co/MPC+PMS system achieved over 99% ATZ degradation within just 4 min, outperforming its conventionally prepared counterpart (Co/BC) (77%). The catalyst demonstrated robust performance across a range of PMS dosages and pollutant concentrations, with minimal interference from coexisting inorganic ions (Cl − , SO 4 2− , NO 3 − , H 2 PO 4 − , HCO 3 − ) and organic humic acid in the Co/MPC+PMS system. Radical quenching experiments and electron paramagnetic resonance (EPR) analysis identified hydroxyl radicals (⋅OH) and sulfate radicals (SO₄⋅⁻) as the dominant reactive species responsible for the rapid degradation. This work highlights the significant advantage of microwave-assisted synthesis in creating advanced carbon-metal catalysts and offers a highly efficient, stable, and practical solution for the remediation of persistent organic pollutants like ATZ without requiring additional energy input. Graphical The alternative text for this image may have been generated using AI. Microwave-assisted preparation of Co/MPC for efficient PMS activation towards atrazine degradation.
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Nano-Micro Letters
·
2026
·Vol. 18
·期 1
·391
·
IF 38.5
Lu Hui,Yu Yang,Wu Wenqiang,He Zeping,Hu Kaiyu,Yang Wenqiang,Han Xun,Pan Caofeng
Perovskite single-crystal heterojunction arrays exhibit significant application potential in advanced optoelectronics, however, achieving comprehensive control over crystallographic and spatial properties of the array remains challenging. Here, we report a selective epitaxial growth strategy for fabricating single-crystal MAPbCl3/MAPbBr3 and MAPbBr3/MAPbI3 heterojunction arrays. This method employs patterned polymer templates to define the pixel dimension and arrangement, while the underlying single-crystal substrate guides the crystal orientation of the heterojunction array, enabling precise control over the pixel size, pixel arrangement angle and crystal plane. The self-powered photodetector arrays were fabricated based on these heterojunctions, showing a specific detectivity of 6.0 × 1011 Jones, a weak-light detection limit of 9 nW cm−2 and long-term operation stability under zero bias. Furthermore, the light pattern with different illumination intensities could be clearly imaged by the device array in the self-powered mode. This work establishes a robust method of fabricating the single-crystal heterojunction arrays for advanced optoelectronic applications.
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JOURNAL OF FLUORESCENCE
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2026
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IF 3.4
Wu Hanqing,Xu Shichang,Wu Wenxiu,Zeng Hongyu,Yang Kai,Xu Jingshui
Copper ions (Cu²⁺) are essential trace elements that play a vital role in maintaining physiological activities, while their homeostasis imbalance is associated with the pathogenesis of various diseases. Therefore, developing a highly selective and sensitive detection method for copper ions (Cu²⁺) is of significant importance. This study successfully synthesized a novel fluorescent probe, tetraphenylimidazole derivative (TPHB), for the specific recognition of copper ions (Cu²⁺). It exhibits excellent optical properties, including fluorescence quenching upon Cu²⁺ binding. The detection limit reaches as low as 0.047 µM, with a binding constant (K) of 3.56 × 10⁴ M − ¹, demonstrating its high sensitivity. Fluorescence calibration curves, mass spectrometry, and ¹H NMR spectroscopy confirmed a 2:1 Cu²⁺ binding ratio for TPHB. It exhibits strong resistance to interference from common ions such as Al³⁺. Furthermore, it was successfully applied in rapid detection test strips, demonstrating excellent detection performance in simulated water samples.
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NATURE
·
2026
·
IF 56.1
Guan Ningzi,Kong Deqiang,Gao Xianyun,Niu Lingxue,Zhou Yang,Yu Guiling,Gao Tian,Liu Mengyao,Ma Wenbo,Jin Yiyu,Yin Jianli,Zhao Shangang,Ye Haifeng
Sustained and controlled delivery of glucose-lowering agents using engineered designer cells is recognized as an effective strategy for diabetes therapy 1 . However, current technologies rely on external signal control or have been programmed into mammalian cells using synthetic gene networks, which pose safety concerns arising from transplantation 2 , 3 . Here we developed an engineered oral-deliverable g lucose-sensing and functional response probiotic living drug for ‘sense-and-respond’-based control of diabetic blood glucose. We created a glucose sensor based on a synthetic gene circuit that incorporates the glucose-responsive transcriptional regulator HexR, coupled with a synthetic promoter. Upon oral administration of the engineered probiotics carrying the sensor, the cells reside temporarily in the intestine and regulate the expression of therapeutic transgenes in response to glucose levels that exceed the normal threshold. We show efficacy from the engineered probiotics for glycaemic control in multiple diabetic mouse and non-human primate models, demonstrating that long-term oral administration drives clear improvements in lipid profiles, while also attenuating development of multiple diabetic complications. Our probiotics-based living drug enables therapeutic dosing in response to real-time blood glucose levels, providing a programmable, orally deliverable sense-and-respond platform for metabolic therapy without transplantation.
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JOURNAL OF NANOBIOTECHNOLOGY
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2026
·
IF 15
Bo Peng,Jing Yang,Rui Lin,Yuling Han,Hongning Wang,Runqi Zhou,Tong Yan,Shilin Liu,Hanwei Jiang,Yunshan Li,Tianshu Zhang,Yuhao Peng,Xinyu Xue,Huawei Shen,Jinlin Song,Ximu Zhang
Periodontitis is a prevalent chronic inflammatory disease that causes progressive periodontal tissue loss and systemic complications. However, conventional therapies often remove biofilms without fully resolving inflammation or regenerating tissue. Here, we report a flexible wireless ultrasonic patch loaded with ZIF-8 nanoparticles containing the anti-inflammatory antioxidant senkyunolide A (SenA@ZIF-8) for on-demand drug release. A piezoelectric transducer converts 1 MHz ultrasound into ≈ 10 V, 9 mA electrical output, heating a tridecanoic acid phase-change matrix to ≈ 43 °C to trigger SenA@ZIF-8 release. In vitro, SenA@ZIF-8 was biocompatible and outperformed free SenA in protecting periodontal ligament stem cells from H₂O₂-induced oxidative damage: it reduced intracellular ROS levels and restored the activity of antioxidant enzymes. In macrophages, ZIF-8 loading enhanced intracellular SenA uptake and markedly suppressed LPS-induced proinflammatory mediator expression while promoting M2 marker expression. In a rabbit model of ligature-induced periodontitis, repeated ultrasonic-triggered SenA@ZIF-8 delivery markedly reduced periodontal inflammation. Micro‑computed tomography (Micro-CT) and histology showed that the device-treated sites exhibited the greatest alveolar bone regeneration and collagen deposition, accompanied by minimal inflammation. This innovative MOF-based ultrasonic patch can relieve oxidative stress and inflammation through minimally invasive, precise, and on-demand drug delivery, thereby promoting periodontal regeneration. This approach has significant translational potential as an adjunct therapy to improve periodontal treatment outcomes and patient compliance.
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CHEMICAL PAPERS
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2026
·
IF 2.7
Zhu Li,Gao Xizi,Zhang Lijuan,Zhang Jun,Guo Sheng
Advanced oxidation processes (AOPs) based on persulfate (PS) have been widely applied in environmental remediation owing to their ability to generate strong oxidizing reactive species. However, the traditional homogeneous and heterogeneous PS activation systems are prone to cause secondary pollution problems such as the leaching of toxic metals or the formation of sludge. To overcome these technical bottlenecks, this study constructed a ternary catalyst-free system coupling mechanical stirring (MA), ultrasonic irradiation (US), and PS, aiming to efficiently degrade organic contaminants in water bodies. In the proposed MA/US/PS system, peroxymonosulfate (PMS) demonstrates a significantly higher removal rate of Rhodamine B (RhB) than those of sodium persulfate (PDS), ammonium persulfate (PNS), and hydrogen peroxide (H 2 O 2 ) under the same conditions, which could be associated with the asymmetry structure of PMS, potentially facilitating its activation. Moreover, the MA/US/PMS system maintains stable catalytic activity over a broad pH range (3.09–10.52) and demonstrates excellent degradation efficiency in the presence of various coexisting anions and in actual water matrices. The effects of key operational parameters such as PMS dosage, agitation speed, ultrasonic power, and temperature on the degradation efficiency is comprehensively investigated. By combining radical quenching tests and electron paramagnetic resonance (EPR) techniques, the dominant reactive species responsible for RhB removal are identified. This work proposes an efficient, green, and catalyst-free activation strategy for PMS, which holds great potential for the advanced treatment of actual wastewater.
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ANALYTICAL AND BIOANALYTICAL CHEMISTRY
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2026
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IF 4.1
Tang Xiaoting,Xu Zhengyi,Liu Yafeng,Du Xiaoxia,Lu Xinqiong,Li Hua
This paper proposes a plasma modification-trichlorosilane impregnation composite process for fabricating paper microfluidic channels, which is applied to paper spray mass spectrometry detection of prohibited drugs in serum samples from health supplement addition. Plasma modification plays a dual core role: precisely constructing hydrophilic microchannels on silane-impregnated filter paper and stripping surface residual impurities and ash to optimize physicochemical properties. The plasma-modified microchannel paper spray ionization system (PM-PSI) significantly reduces sample loss during migration versus conventional paper spray ionization (PSI), thus enhancing the detection signal of target analytes in blood samples. Combined with filter paper’s matrix effect mitigation and plasma-induced surface optimization, PM-PSI exhibits better detection efficiency than traditional electrospray ionization (ESI) for direct blood sample analysis. Performance validation with venlafaxine showed that PM-PSI increased the signal intensity by 3–5 times and reduced the relative standard deviation (RSD) by 5–6 times compared with PSI at 50–500 ng/mL, and the signal intensity was 10–30 times higher than that of ESI. Quantitative analysis of four typical prohibited drugs (venlafaxine, reserpine, risperidone, sildenafil) revealed their linear range of 1–1000 ng/mL with a significantly improved coefficient of determination (R 2 ) versus PSI. Moreover, PM-PSI coupled with a domestic miniaturized mass spectrometer successfully detected the parent ions of the four drugs at 300 ng/mL, confirming its suitability for complex sample analysis of miniaturized mass spectrometers and providing a technical solution for rapid on-site testing. Graphical abstract A plasma modification-trichlorosilane impregnation process fabricates paper microfluidic channels for paper spray mass spectrometry detection of prohibited drugs in blood. Plasma modification constructs hydrophilic microchannels on silane-impregnated filter paper while removing surface impurities. The plasma-treated paper spray ionization system (PT-PSI) reduces sample loss versus conventional PSI, enhancing detection signals. PT-PSI outperforms electrospray ionization (ESI) for direct blood analysis, increasing signal intensity 3–5-fold versus PSI and 10–30-fold versus ESI, while reducing relative standard deviation 5–6-fold. Quantitative analysis of four drugs (venlafaxine, reserpine, risperidone, sildenafil) showed a linear range of 1–1000 ng/mL with improved R 2 .
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Nature Communications
·
2026
·
IF 18.1
Hu Zhong-Ting,He Gan,Tao Xiaohuan,Tian Jinshu,Tan Mingwu,Ouyang Ni,Li Jun-Long,Hu Mian,Wang Jie-Xin,Zhu Yihan,Cao Dapeng,Pan Zhiyan,Wang Yong,Li Xiaonian
The catalytic oxidation of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid is a key step in the production of bio-based plastics but remains limited by sluggish multi-electron transfer kinetics across multiple reaction intermediates. In this study, we address this long-standing challenge by introducing a Mn-O-Co electron bridge within spinel CoMn 2 O 4 to mediate and accelerate electron transfer. Through precise valence state regulation, we engineer a heterogeneous electron bridge dominated by Mn 4+ -O 2- -Co 3+ linkages, enabling more efficient electron flow. Experimental characterization and theoretical calculations reveal that the incorporation of Mn 4+ significantly enhances electron delocalization across the bridge. The empty e g orbitals of Mn 4+ ( t 2g 3 e g 0 ) serve as efficient electron acceptors, creating an energy-level gradient with Co 3+ ( t 2g 4 e g 2 ) that favors directional electron transfer. Simultaneously, Mn 4+ strengthens metal-oxygen covalency, further improving electron mobility. This engineered electron bridge structure enables highly efficient cooperation across the full six-electron transfer pathway in 5-hydroxymethylfurfural oxidation, driven by a dynamic electron compensation mechanism. As a result, an 2,5-furandicarboxylic acid yield of 98.1% is achieved. This work offers a valuable theoretical foundation for understanding cooperative electron transfer in heterogeneous catalysis and provides a rational strategy for designing efficient electron bridge structures.
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JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
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2026
·
IF 3.4
Li Mengyuan,Li Hang,Zhang Manman,Wang Tong,Wang Yongsheng,Wang Zhihan,Wang Shihan
This work developed an ultrasound-assisted enzymatic extraction (UAEE) method for producing Rana chensinensis ovum oil (RCOO), a valuable source of omega-3 and omega-6 fatty acids. After screening various proteases for enzymatic pretreatment, the Box-Behnken design (BBD) was employed to optimize the extraction conditions. The optimized parameters, ultrasound duration of 75 min, ultrasound power of 371 W, enzyme amount of 1% (w/w of RCO), and incubation time of 81 min, yielded 14.67 ± 0.06% oil, a result consistent with the predicted value of 14.7%. HPLC analysis revealed that the RCOO extracted by UAEE contained a higher proportion of unsaturated fatty acids compared to the conventional method. Furthermore, antioxidant assessments (DPPH and ABTS radical scavenging assays) demonstrated that UAEE-derived oil exhibited superior antioxidant activity compared to oils obtained via ultrasound extraction (UE) or supercritical fluid extraction (SFE). These results establish UAEE as an efficient and sustainable approach for producing high-quality RCOO with enhanced bioactive properties. Graphical abstract
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Journal of Food Measurement and Characterization
·
2026
·
IF 3.6
Chen Linlin,Yu Xiao,Li Wei,Zhang Haipeng,Zhang Sicong,Xin Jiaying,Zhang Na
Ferulic acid exists in nature mainly in the bound state in plant cell walls and is found in grains, fruits, vegetables, and Chinese herb.FA has a wide range of biological activities. However, the low stability and water solubility of FA limit its bioavailability. This has led to the encapsulation of FA to improve its bioavailability. This study prepared the binary polysaccharide-based carrier β-cyclodextrin/debranched rice starch (β-CD/DRS) by ultrasonic self-assembly. The particle size of β-CD/DRS was 107.23 ± 2.14 nm with a PDI index of 0.311 ± 0.075, which is affected by ultrasound time. The ternary inclusion complex of FA@β-cyclodextrin/debranched starch (FA@β-CD/DRS) was synthesized by the co-deposition method; the encapsulation and loading rate of FA were 89.32 ± 2.53% and 7.48 ± 0.54%, respectively. The structures of the ternary inclusions were analyzed by SEM, FT-IR, XRD, and DSC. The β-CD/DRS assembled using different ultrasound times modulated the FA@β-CD/DRS properties after deposition. The results showed that the inclusion compound was 1.22 times more photostable and 1.44 times more thermostable than FA. In the simulated gastrointestinal tract, the optimal in vitro release kinetics model was a first-order kinetic model, which was affected by pH. At pH 8.0, the cumulative release of ferulic acid was higher. The inclusion complex can continuously release ferulic acid, achieving a sustained-release effect, and its solubility in water is 3.9 mg/mL, which is approximately six times that of ferulic acid. In summary, the use of binary polysaccharide-based vector encapsulation can provide a more efficient method for the stabilization and delivery of phenolic acids. Graphical
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POLYMER JOURNAL
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2026
·
IF 3.1
Liu Dongfang,Zhang Di,Jibamo Awai,Zhang Yuanyuan,Huang Liqin,Jiang Dong,Zhao Yaxin
This study focuses on microenvironmental changes under different forces and involves the construction of a series of sodium lauroyl glutamate (LGS) supramolecular hydrogel systems, including LGS hydrogel, LGS-E gel, and LGS/APG hydrogel. This research indicates that the formation of LGS supramolecular hydrogels relies on the synergy between hydrogen bonding and hydrophobic interactions. It has a specific formation range and exhibits dual responsiveness to temperature and pH. The LGS-E gel system is based on weak hydrophobic interactions and can only form in a mixed water/ethanol system, indicating relatively weak temperature responsiveness. The LGS/APG hydrogel system utilizes strong hydrogen bonding to considerably broaden the formation range of the gel phase. Although its mechanical properties are slightly reduced, its stability and the universality of formation are improved. In this study, by regulating the balance between hydrogen bonding and hydrophobic interactions, the structural design and performance regulation of LGS supramolecular hydrogels were achieved, providing theoretical and experimental support for their application in relevant fields.
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PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
·
2026
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IF 3.5
Bekena Fekadu Tadesse,Kuo Dong-Hau,Duresa Lalisa Wakjera
Photocatalysis is one of the latest and the most promising technologies to remove organic pollutants from the environment. In this work, novel Nb/Co-codoped MoOS photocatalyst was prepared by a simple chemical precipitation method and thereafter the as-prepared photocatalysts were systematically characterized by different techniques. The photocatalytic performance of the as-prepared samples was surveyed by the degradation of methyl orange (MO), rhodamine B (RhB), and methylene blue (MB) dyes under visible light irradiation. All the codoped photocatalysts exhibited enhanced photocatalytic activity than pure and mono doped samples for degradation of these dyes with the highest degradation efficiency observed for the sample with 10 % Nb amount, which degrade 94.4 % of MO, 97.1 % of RhB, and 99.7 % of MB within 150, 20, and 40 min irradiation time, respectively. The HPLC test further confirmed the degradation of these dyes. The rate constants of MO, RhB, and MB removal in the photodegradation process over 10Nb-10Co-MoOS were determined. The enhanced photocatalytic activity of the sample was due to high charge separation and inhibition of recombination of photogenerated electron-hole pairs. The scavenger studies indicate that the primary active species in the photocatalytic process for MO and MB were superoxide radicals and for RhB were hydroxyl radicals, indicating 10Nb-10Co-MoOS had be widely used for different dye degradation. The catalyst revealed excellent recyclability and stability even after three runs. Finally, a reasonable reaction mechanism was proposed.
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