查找使用阿拉丁产品的科研文献

Ultrathin absorption-dominated PAN-derived porous carbon membranes enabled by Fe(acac)3 for efficient EMI shielding

Saijia Dong,Renyuan Yang,Xiaonan Liu,Yue Wang,Yupeng Hu,Daohai Zhang,Teng Zhou

Lightweight, ultrathin, and absorption-dominated electromagnetic interference (EMI) shielding materials are highly desired to alleviate secondary electromagnetic pollution caused by conventional reflection-dominated shielding materials. Herein, Fe(acac) 3 -assisted PAN-derived porous carbon membranes were fabricated through nonsolvent-induced phase separation (NIPS), freeze-drying, and high-temperature carbonization to achieve efficient absorption-dominated EMI shielding performance. The interconnected porous conductive carbon framework facilitated the dissipation of incident electromagnetic waves by providing continuous conductive channels and abundant internal scattering interfaces. Different Fe(acac) 3 contents were introduced to evaluate their influence on graphitization degree, electrical conductivity, and EMI shielding performance. Notably, with only 1 wt% Fe(acac) 3 loading, the obtained C-P-P/AcFe-2 membrane with a thickness of only 0.42 mm exhibited the best overall shielding performance, including an electrical conductivity of 7.12 S mm −1 , exhibiting an average EMI shielding effectiveness of 94.9 dB and a corresponding SE A value of 80.2 dB in the X-band. The SE A /SE R ratio reached 5.5, indicating obvious absorption-dominated shielding behavior. Meanwhile, the SSE t value reached 4013.4 dB cm 2 g −1 , demonstrating its lightweight shielding capability. This work provides a feasible approach for developing lightweight, ultrathin, low-filler-loading, and absorption-dominated EMI shielding materials. Download: Download high-res image (272KB) Download: Download full-size image A lightweight and ultrathin porous carbon membrane was developed by introducing Fe(acac) 3 as a molecular-level precursor to construct an interconnected conductive network and magnetic components. The optimized membrane achieves absorption-dominated EMI shielding with a shielding effectiveness of 94.9 dB and an absorption contribution of 80.2 dB at a thickness of only 0.42 mm.

Assessment of p-Xylene Migration Behaviour in Unsaturated Soil Systems: A 3-D Sand Flow Chamber Study

The influence of soil water content and contaminant injection pressure on the migration behaviour of p-Xylene (one of the organic pollutants in Benzene Toluene Ethylbenzene & Xylene) is investigated in the unsaturated zone using the controlled laboratory sandbox experiments. The results show that, at equivalent migration distances, higher soil water content leads to longer migration durations and reduces transport velocities, whereas greater injection pressure promotes faster contaminant movement. These findings highlight the governing role of water saturation in the water–oil–gas three-phase system, in which increased water content decreases the relative permeability of the oil phase and retards capillary-driven BTEX transport. Unlike many previous studies in which contaminants commonly migrate downward toward the groundwater table, the BTEX in this study did not reach the water table and exhibited partial upward migration. Overall, the results provide experimental-scale insight into key mechanisms governing BTEX transport in unsaturated sandy media and serve as a reference for improving predictions of contaminant fate and migration pathways in field settings.

Oxygen-Vacancy-Rich Na1.3Ti1.8Ni0.1Sb0.1(PO4)3@C Anode for High-Rate and Low-Temperature Sodium-Ion Storage

He Yixin,Wang Yida,Zeng Sihan,Si Juntao,Li Yuexin,wang Rui,Zhang Cheng,Chen Chunhua

NASICON-type NaTi 2 (PO 4 ) 3 as an electrode material for sodium-ion batteries has attracted considerable attention due to its high structural stability and safety, yet its low intrinsic electronic conductivity limits high-rate and low-temperature performance. In this work, an oxygen-vacancy-rich Na 1.3 Ti 1.8 Ni 0.1 Sb 0.1 (PO 4 ) 3 @C (N 1.3 T 1.8 N 0.1 S 0.1 P@C) nanopowder as a high-performance anode material is synthesized by a solvothermal method. The Ni 2+ /Sb 5+ co-doping effectively modulates the local TiO 6 /PO 4 lattice environment, introduces oxygen vacancies, and optimizes the lattice electronic structure, enhancing both electron and ion transport. A continuous carbon coating forms a stable conductive network, further improving kinetics and structural integrity. As a result, Na∥N 1.3 T 1.8 N 0.1 S 0.1 P@C half-cells retain 91% of their capacity after 5000 cycles at 20 C and maintain 86% capacity over 10,000 cycles at 10 C under 0 ° C. The full cell paired with Na 3 V 2 (PO 4 ) 3 cathodes exhibits 87% capacity retention after 1000 cycles at 5 C and delivers excellent performance even at 50 C without pre-sodiation, highlighting their potential for low-temperature applications. This study provides a general doping-defect engineering strategy for NASICON-type anodes, enabling high-rate, low-temperature, and long-cycle performance for sodium-ion batteries.

A synergistic nanotherapy for skin photoaging via self-assembly of epigallocatechin-3-gallate and recombinant human collagen

Xia Huan,Huang Rufei,Wu Qihong,Tang Xun,Meng Tao,Fan Yufei,Li Ziyi,Zhang Jinping,Huang Yadong,Yang Yan

UV-induced skin photoaging is a complex pathology driven by oxidative stress and extracellular matrix (ECM) depletion. Although recombinant human collagen (RHC) and epigallocatechin-3-gallate (EGCG) address these mechanisms, their synergy is limited by RHC’ s poor permeability and EGCG’ s instability. Here, we present a supramolecular co-assembly strategy to overcome these barriers. Validated by molecular dynamics simulations, we utilized the intrinsic proline-rich domains of RHC as anchors for EGCG to construct uniform nanospheres (< 100 nm). This architecture sterically shields EGCG, significantly enhancing stability and reducing cytotoxicity. Biologically, the nanospheres restored mitochondrial membrane potential and promoted anti-inflammatory M2 macrophage polarization. In a photoaging mouse model, the nanospheres outperformed monotherapies, effectively reversing epidermal hyperplasia and restoring the Type I/III collagen ratio. This study resolves the delivery-stability paradox of protein–polyphenol therapeutics, offering a potent strategy for regenerating photodamaged skin. Graphical

A NASICON-type structure NaAlNb(PO4)3:Cr3+ phosphor with both high efficiency and thermal quenching resistance

Weijie Yan,Tao Li,Peihong Shi,Zhaoqi Hu,Jinliang Huang,Wenfa Fang,Libin Xia

NIR pc-LEDs develop rapidly due to its spectral tunability and compact design. However, NIR phosphors with both high efficiency and superior thermal quenching resistance are scarce. In this study, a novel NASICON-type structure phosphate NaAlNb(PO 4 ) 3 :Cr 3+ phosphor was synthesized successfully. The crystal structures and the luminescence behaviors were systematically investigated. The phosphor exhibits a broadband NIR emission from 700 to 1100 nm, centered at 808 nm and with a full-width at half maximum (FWHM) of 131 nm. Owing to the high structural rigidity (Θ D = 624.9 K) and wide optical bandgap (E g = 4.1 eV), NaAlNb(PO 4 ) 3 :Cr 3+ shows a high internal quantum efficiency (IQE) of 87% and excellent thermal quenching resistance (retaining 84.19% of its room-temperature intensity at 373 K). A NIR pc-LED was fabricated by combining the as-prepared phosphor with a 460 nm blue LED chip, achieving a high photoelectric conversion efficiency of 18.37% and a strong NIR output power of 50.19 mW at a driving current of 100 mA. All results indicate the NaAlNb(PO 4 ) 3 :Cr 3+ is a promising phosphor for NIR light practical applications.

Preparation of a novel flavin-adsorbing biocarrier and its accelerating mechanism on anaerobic bioreduction of 3-nitrobenzenesulfonate

Ze Fu,Hong Lu,Shaoting Zhuo,Jichao Wang,Qiansheng Li,Xiaona Li,Haikun Zhang

To harness the potential of low-concentration, microbially secreted flavins as redox mediators, a novel biocarrier was designed via molecular simulation and synthesized via covalently grafting 2-chloro-4,6-diamino-1,3,5-triazine (CDAT) onto reduced graphene oxide (rGO)-modified polyurethane foam (CDAT-rGO-PUF). CDAT-rGO-PUF exhibited higher adsorption capacity for flavins and more efficiently resisted the interference of inorganic salt and cell lysate compared with rGO-PUF and CDAT-PUF, which was primarily attributed to the formed hydrogen bonding between CDAT and flavins. In Shewanella sp. RQs-106 -mediated reduction system of 3-nitrobenzenesulfonate (3-NBS), the adsorption behavior of CDAT-rGO-PUF accelerated extracellular electron transfer from flavin to rGO and cellular synthesis of flavins, resulting in over 37% increase in the bioreduction rate of 3-NBS compared with those in the presence of rGO-PUF and CDAT-PUF. Repeated usage experiments showed that CDAT-rGO-PUF had good catalytic stability. These findings indicate that the novel biocarrier is of potential application for adsorbing extracellular flavins to enhance the treatment of wastewaters containing nitroaromatic compounds.

Lattice-homogenized Br/I alloyed CsPb(Br/I)3 red quantum dots for wide-color-gamut WLEDs

Siyu Qin,Yanzhao Liu,Zhanghan Qin,Yi Zhu,Yulong Zhao,Meirong Sui,Feng Tong,Xiuquan Gu

All-inorganic red-emitting CsPbI 3 perovskite quantum dots (PQDs) suffer from cubic-phase instability and iodide ion migration, causing phase separation and emission quenching. This work demonstrates that lattice-level Br/I homogenization is essential for stable red emission, rather than physical blending or surface doping. Through systematic compositional screening of CsPb(Br/I) 3 solid solutions, CsPbBr 1 I 2 is identified as the optimal composition, delivering pure emission at 640 nm. Br incorporation strengthens Pb–Br bonds, passivates halide vacancies, and synergistically suppresses phase transitions and ion migration. As a result, CsPbBr 1 I 2 PQDs exhibit an ultralong fluorescence lifetime of 288 ns and retain over 70% of initial photoluminescence (PL) intensity under combined heat, water immersion, and light stresses, whereas control samples retain only 30−40%. A prototype white light-emitting diode (WLED) backlight display fabricated with these PQDs achieves a color gamut covering 127.07% NTSC and 94.88% Rec.2020, delivering vivid, saturated colors. This work provides a reliable compositional regulation strategy and theoretical foundation for perovskite-based wide-color-gamut displays.

Loganic Acid Ameliorates Rheumatoid Arthritis via the Lactobacillus murinus-Inodole-3-Acetic Acid–AhR–IL-10 Axis

Weiling Tan,Yufang Fu,Wanyu Hu,Yating Lin,Jingni Cai,Xuelin Huang,Yinyi OuYang,Sheng Lin,Ling Ye

Loganic acid (LA), a major iridoid glycoside from Gentiana macrophylla Pall., possesses anti-inflammatory and immunomodulatory properties, but its therapeutic potential in rheumatoid arthritis (RA) and its interaction with the gut microbiota remain poorly defined. Here, we show that LA markedly and dose-dependently attenuates disease severity in collagen-induced arthritis mice, as evidenced by reduced clinical arthritis scores, systemic inflammatory cytokines, and synovial tissue damage. LA reshaped the gut microbiota, and fecal microbiota transplantation from LA-treated donors partially reproduced its protective effects, indicating a causal contribution of the altered microbial community. In particular, LA selectively enriched OTUs annotated as Lactobacillus murinus ( L. murinus ) and increased levels of the microbial tryptophan metabolite indole-3-acetic acid (IAA). Both LA and IAA activated aryl hydrocarbon receptor (AhR) signaling, suppressed tumor necrosis factor-α-induced inflammatory responses in human synoviocytes, and, in vivo, enhanced IAA–AhR–interleukin-10 (IL-10) signaling in arthritic joints. Pharmacological inhibition of AhR with CH223191 substantially reversed LA's therapeutic effects, demonstrating that AhR signaling plays a critical role in its anti-arthritic activity. Collectively, these findings demonstrate that LA protects against RA through a dual mechanism: direct activation of AhR in joint tissues and indirect reinforcement of AhR signaling through an L. murinus -associated microbial IAA axis. This study highlights a gut microbiota–metabolite–AhR pathway as a key mediator of LA's anti-arthritic effects and supports LA as a promising microbiota-informed therapeutic candidate for RA.

pH-Responsive Folate-PEG modified ZIF-8 Nanoparticles Deliver Fisetin to Aquaporin-3 for Cervical Cancer Therapy

Hanlin Yang,Weiwei Li,Hailong Zhang,Yameng Liu,Miaomiao Cui,Yurong Zhu,Li Hou,Shaoju Min,Jie Ren,Yujie Tan

Conventional cervical cancer therapies often cause severe side effects and face recurrence challenges. Although the natural flavonoid fisetin (FIS) exhibits strong anticancer properties, its clinical utility is restricted by poor aqueous solubility. To overcome this, we engineered a tumor-targeting nanotherapeutic, PEG-FA@ZIF-8@FIS, by encapsulating FIS within a zeolitic imidazolate framework-8 (ZIF-8) core surface-functionalized with polyethylene glycol-folic acid(PEG-FA). Both in vitro and in vivo models demonstrate that this system effectively suppresses cancer cell proliferation, migration, and tumor growth with excellent biocompatibility. Mechanistically, transcriptomic and lipidomic analyses reveal that PEG-FA@ZIF-8@FIS exerts its anticancer effects by downregulating aquaporin-3 (AQP3) expression, which subsequently disrupts tumor lipid metabolism. By linking AQP3 inhibition to metabolic impairment via a targeted delivery platform, this work establishes a highly biocompatible and effective translational strategy for cervical cancer intervention.

High-entropy design in (Ba0.85Sr0.15)TiO3–Bi(Mg2/3Ta1/3)O3 ceramics with temperature-stable dielectric performance

Xinying Zhu,Mingchen Mei,Dingxin Wang,Song Liu,Rui Liu,Xi Kong,Letao Yang,Houbing Huang

Ceramic capacitors with stable dielectric responses at elevated temperatures are of great importance for advanced electronic applications. In this study, high-entropy-engineered (Ba 0.85 Sr 0.15 )TiO 3 –Bi(Mg 2/3 Ta 1/3 )O 3 solid solutions were developed to achieve broad-temperature dielectric stability. Among them, the composition with 25% and 30% Bi(Mg 2/3 Ta 1/3 )O 3 exhibit excellent dielectric properties, exhibiting room-temperature relative dielectric constants of 663 and 680, and dielectric losses of 0.6% and 1.1%, respectively. Particularly, they meet the X9R and X10R specification and dielectric loss of ∼0.6%, with capacitance variation less than ±15% from −74 °C to 265 °C, satisfying the X9R. The composition with 30% Bi(Mg 2/3 Ta 1/3 )O 3 shows the room-temperature dielectric constant of ∼680 and the dielectric loss of ∼1.1%, and showing TCC values within ±15% from −60 °C to 300 °C, which meets the X10R requirement. The improved dielectric temperature stability is associated with high-entropy-induced relaxor behavior together with enhanced high-temperature insulation characteristics, which jointly suppress dielectric loss and leakage current over a broad temperature range. These results demonstrate that high-entropy design is an effective route for developing high-performance temperature-stable dielectric materials for high-temperature capacitor applications.

GSH-Responsive Co-Delivery of Chrysin and 3-Methyladenine Disrupts Tumor Adaptive Stress for Synergistic Antitumor Therapy

Kong Wenbin,Su Baoqiang,Gu Han,Huang Weiqiang,Wang Jing,Zhu Yaqi,Xu Rongrong,Tong Dali,Xu Weiping

Cancer remains a major global health challenge, and conventional therapies are still limited by poor tumor specificity, therapeutic resistance, and systemic side effects. Herein, we developed a glutathione (GSH)-responsive FFSSFF coacervate system for the codelivery of chrysin (CH) and the autophagy inhibitor 3-methyladenine (3-MA) to induce tumor-selective autophagic stress. CH activated endoplasmic reticulum stress and promoted autophagy through the GRP78/PERK and Akt/mTOR signaling pathways, while 3-MA simultaneously disrupted autophagic flux, leading to intracellular homeostasis imbalance, mitochondrial dysfunction, excessive reactive oxygen species accumulation, and tumor cell death. The resulting CH/3-MA@FFSSFF coacervates exhibited favorable physicochemical properties, GSH-responsive behavior, efficient intracellular uptake, and selective accumulation in tumor cells. Both in vitro and in vivo experiments demonstrated potent antitumor activity of the CH/3-MA@FFSSFF system. In particular, in an orthotopic lung cancer model, CH/3-MA@FFSSFF effectively suppressed tumor growth, prolonged median survival time, and inhibited tumor cell migration and invasion. Collectively, this study presents a promising liquid–liquid phase separation-derived coacervate platform for targeted combinational cancer therapy through the induction of autophagic stress, with enhanced therapeutic efficacy and reduced off-target toxicity.

3-Monochloro-1,2-propanediol disrupts ovarian germline stem cell maintenance via Golgi stress-induced autophagy in Drosophila

Zongzhong Liu,Yurong Song,Binbin Xie,Pengpeng Xia,Junlin Yang,Jiazuo Zhu,Hua Wang,Tian Wei

The ubiquitous food processing contaminant 3-monochloro-1,2-propanediol (3-MCPD) poses a potential threat to female reproductive health, yet the underlying mechanisms remain largely undefined. Here, we demonstrate that 3-MCPD exposure impairs ovarian function by disrupting germline stem cell (GSC) maintenance in Drosophila . 3-MCPD exposure dose-dependently induced ovarian atrophy, reduced fecundity, and GSC loss. Mechanistically, 3-MCPD triggered Golgi stress, leading to Mitf-dependent transcriptional upregulation of Atg9 . This, in turn, activated autophagy, which selectively degraded E-cadherin, a critical adhesion molecule for GSC maintenance. Notably, GSC-specific E-cadherin overexpression or Atg9 knockdown effectively rescued 3-MCPD-induced ovarian defects. We further identified a direct physical interaction between Atg9 and E-cadherin, corroborated by immunofluorescence co-localization and AlphaFold3 modeling, which revealed high-affinity binding interfaces that likely mediate this selective autophagic degradation. Both E-cadherin and Atg9 exhibit high evolutionary conservation, underscoring the translational relevance of our findings. This study delineates a novel Golgi stress-Mitf-Atg9 axis through which a prevalent food contaminant compromises female fertility, thereby identifying potential targets for intervention.