Materials Science & Engineering C-Materials for Biological Applications
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2020
·
IF 5.88
Zhong-Hui Wang,Yun-Fei Zhang,Xiao-Wen Sun,Ying-Jie Li,You-Ming Zhang,Tai-Bao Wei,Hong Yao,Qi Lin
Paraquat, one of non-selective herbicides, is widely used in agricultural production. However, it can cause death of people or animals quickly owing to its fatal toxicity. In the present work, for efficient separation and removal of the paraquat, a concept “employ collaboration effect to enhance the Host-Guest interactions” was rationally introduced into the design of paraquat adsorbent material. According to this concept, a novel linear tri-pillar[5]arene-based acceptor molecule was synthesized. Interestingly, the acceptor shows outstanding adsorption properties for paraquat through the collaboration effect of the adjacent pillar[5]arene moieties in the linear tri-pillar[5]arene acceptor. Compared with other adsorbents such as activated carbon and single-pillar[5]arene-based adsorbent materials, the linear tri-pillar[5]arene acceptor shows higher adsorption rate for paraquat. Additionally, the linear tri-pillar[5]arene acceptor was applied to adsorb the commercial pesticide paraquat sample in water with adsorption rate of 98%. Therefore, the linear tri-pillar[5]arene acceptor could serve as a paraquat adsorbent material and convey greatly potential application in the field of removal of paraquat. The concept “employ collaboration effect to enhance the Host-Guest interactions” is a useful way for the development of adsorption materials.
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JOURNAL OF FOOD PROTECTION
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2020
·
IF 1.581
Hongying Li,Qiujin Zhu,Rui Chang,Ke Hu,Xuling Zhu,Aqi Xu,Shitao Xu,Pengyu Tang
ABSTRACT In order to reduce the health risks associated with red meat as listed by the World Health Organization, the work presented in this article aimed to elucidate the interaction between 5′-CMP–supplemented feed and N -glycolylneuraminic acid (Neu5Gc) in experimental animals in vivo. 5′-CMP was added to the diet of 90-, 180-, and 270-day-old Xiang pigs, and after 30 days, the Neu5Gc contents, physicochemical parameters, and free amino acid contents of muscle and internal viscera were measured by high-performance liquid chromatography coupled with fluorescence detection. The mechanism by which 5′-CMP affects Neu5Gc contents was investigated using molecular docking. Results show that 5′-CMP significantly decreased the Neu5Gc content in 180-day-old Xiang pigs ( P < 0.05) but had no effect on the Neu5Gc contents in 90- and 270-day-old Xiang pigs. Umami amino acids were significantly increased in 180-day-old Xiang pigs. In the 90- and 270-day-old pigs, histidine increased by 10.38 and 17.87%, respectively. The other free amino acids were either reduced or not affected. Moreover, the 5′-CMP–supplemented diet did not affect the physicochemical parameters of the longissimus muscle in the Xiang pigs. 5′-CMP could occupy almost all the sialyltransferase active-site residues but not His302 and showed inhibition of the sialyltransferase activity. The results provided an experimental basis for the subsequent reduction of Neu5Gc in red meat before slaughter.
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Processes
·
2020
·Vol. 8
·期 10
·1273
·
IF 2.753
Sha Wen,Kai Liu,Yi Tian,Yanping Xiang,Xianxiang Liu,Dulin Yin
2,5-diformylfuran (DFF) is an important downstream product obtained by selective oxidation of the biomass-based platform compound 5-hydroxymethylfurfural (HMF). In this study, a phosphorus-doped carbon (P-C) supported vanadium phosphate oxide (VPO) catalyst was successfully prepared and showed remarkably high catalytic activity in the selective oxidation of HMF to produce DFF with air as an oxidant. The effects of the reaction temperature, reaction time, solvent, catalyst amount, and VPO loading amount were investigated. The results showed that an HMF conversion rate of 100% and a DFF yield of 97.0% were obtained under suitable conditions, and DMSO was found to be the most suitable solvent under an air atmosphere.Keywords:vanadium phosphate oxides;5-hydroxymethylfurfural;catalysis;selective oxidation;2,5-diformylfuran
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Optical Materials Express
·
2020
·Vol. 10
·期 12
·3359-3371
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IF 3.064
Hefu Li,Hefu Li,Hefu Li,Nan Zhao,Yangzhi Wang,Ruibin Zou,Zhenshan Yang,Changqing Zhu,Minghong Wang,Huishan Yu,Huishan Yu
Nanogap-rich silver nanoislands with fascinating optical properties are desirable substrates for surface-enhanced Raman scattering (SERS). Here, we propose a simple and high-throughput approach through the laser molecular beam epitaxy (LMBE) technique for preparing silver nanoislands containing large numbers of intra-nanogaps on a silicon wafer (6×6 cm2). By optimizing the deposition time, the enlarged silver nanoislands with ∼5 nm interstitial gaps of abundance and homogeneity were formed. Remarkably, the optimized SERS substrate with high-density hotspots demonstrated a high analytical enhancement factor (AEF) as large as 1.17×105, excellent reproducibility with relative standard deviation (RSD) of 7.76% over the entire substrate, and good stability after storage for 21 days. The electromagnetic field distribution of the optimized SERS substrate was simulated using the software COMSOL Multiphysics based on the actual SEM image of the fabricated sample, and the calculated enhancement factor (EF) is as high as 109. Furthermore, it can enable sensitive and quantitative detection of malachite green at concentrations as low as 10−8 M. This simple fabrication of silver nanoislands with homogeneous ∼5 nm interstitial gaps provides a practical solution for wafer-scale, sensitive, and reproducible SERS substrates.
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CATALYSIS TODAY
·
2020
·
IF 5.825
Mengmeng Jin,Linhao Yu,Hong Chen,Xueli Ma,Kai Cui,Zhe Wen,Zewei Ma,Yushuai Sang,Mengmeng Chen,Yongdan Li
Ce oxide-based catalysts with different molar ratio of Co/Ce (denoted as CoCe-x, x represents the Co to Ce ratio) were examined as the catalyst of 5-hydroxymethylfurfural (5-HMF) oxidation to 2,5-furandicarboxylic acid (FDCA). The Co to Ce ratio, catalyst amount and reaction temperature all have remarkable effects on yield and selectivity. Complete conversion of 5-HMF with 86.3 % selectivity of FDCA has been achieved over the CoCe-0.15 catalyst at 130 °C with 0.6 MPa O 2 pressure (gauge) for 4 h. The good performance is attributed to the high specific surface area and the high oxygen vacancy concentration to promote the mobility and adsorption of oxygen species. In addition, the CoCe-0.15 catalyst is reused for five times without significant activity loss. Finally, the reaction mechanism over the CoCe-0.15 catalyst under base-free condition is discussed. 5-HMF is oxidized by the lattice oxygen via Mars-van Krevelen mechanism with the redox of Ce 4+ /Ce 3+ and Co 3+ /Co 2+ , and the lattice oxygen is replenished by adsorbing and activating O 2 molecules.
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GREEN CHEMISTRY
·
2020
·Vol. 22
·期 5
·1630-1638
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IF 9.48
Bin Zhang,Mark Douthwaite,Qiang Liu,Chao Zhang,Qifan Wu,Ruhui Shi,Peixuan Wu,Ke Liu,Zhuangqing Wang,Weiwei Lin,Haiyang Cheng,Ding Ma,Fengyu Zhao,Graham J. Hutchings
A novel method for the synthesis of MFI zeolites has been developed, which does not require any crystal seeds or solvent. The adaptability of this method was also evidenced; a series of ZSM-5 zeolites with differing Si/Al ratios (18∼∞) were synthesized, which to date, has been a challenge in the field of solvent-free synthesis. The materials were probed by in situ DRIFTS and 2D 27Al–19F HETCOR NMR spectroscopy, the results from which indicated that fluorine-containing species play a crucial role in the crystallization of ZSM-5. During the crystallization process F− anions coordinate with Al3+ cations, resulting in the formation of 6-coordinated “F–Al–O–Si” species. It is these intermediate species which drive the formation of tetrahedral [AlO4]− units in the zeolitic framework. The effectiveness of these materials as catalyst supports was subsequently assessed in the hydrogenation of levulinic acid and glucose, which exhibited a comparable performance to commercial ZSM-5. The simple, efficient and low-cost method presented herein provides an alternative approach for the green scaled-up synthesis of zeolites.
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AQUATIC TOXICOLOGY
·
2020
·
IF 4.346
Lei Peng,Chang Wang,Pingdeng Li,Bo Cheng,Yeli Hu,Yang Cheng,Qi Zheng
Halogenated dipeptides, 3, 5-di-I-tyrosylalanine (DIYA), have been identified as novel disinfection byproducts (DBPs), following chloramination of authentic water. However, little is known about their toxicity. Zebrafish embryos were used to assess the toxicity of novel iodinated DBPs (I-DBPs). Although DIYA did not exhibit high acute toxicity to embryonic zebrafish (LC 50 > 2 mM), it significantly inhibited pigmentation of melanophores and xanthophores on head, trunk and tail at 500 μM as determined by photographic analysis. Whereas N-phenylthiourea (PTU) as a pigment inhibitor did not inhibit development of yellow pigments. Colorimetric detection of melanin further confirmed these results. Quantitative real time polymerase chain reaction (qRT-PCR) measurements indicated that genes ( dct , slc24a5 , tyr , tyrp1a , tyrp1b , silva ) associated with the melanogenesis pathway were dramatically down-regulated following exposure to 500 μM DIYA. In addition, enzymatic activity of tyrosinase (TYR) decreased, also demonstrating that the underlying mechanism of hypopigmentation was attributed to the disruption of melanogenesis pathway. Transcription levels of xanthophore genes ( gch2 , bnc2 , csf1a , csf1b , pax7a and pax7b ) were also monitored by qRT-PCR assay. DIYA exposure up-regulated expression of gch2 and bnc2 , but not csf1 and pax7 . Tested DIYA analogues, brominated tyrosine was unlikely to inhibit pigmentation, indicating that the iodine substitution and dipeptides structure are of important structural feature for the inhibition of pigmentation. In this study, we observed that DIYA inhibited melanogenesis related genes, which might contribute to pigmentation defects. Moreover, as an emerging I-DBPs, the developmental toxicity of aromatic dipeptides should be further studied.
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OPTICS AND LASER TECHNOLOGY
·
2020
·
IF 3.233
Gulgina Mamtmin,Nuerguli Kari,Renagul Abdurahman,Patima Nizamidin,Abliz Yimit
Optical waveguide (OWG) sensors are widely used in gas detection, and sensitive materials are the key factors affecting sensor performance. Herein, we report on a 5,10,15,20-tetrakis-(4-methoxyphenyl) porphyrin (TMP) deposited optical wave guide (OWG) sensor. The porphyrin solutions with different acidity were deposited on a K + -ion exchanged glass OWG surface by spin coating, to fabricate porphyrin film-coated OWG gas sensing devices. The effects of pH values of the porphyrin solution used to prepare the sensitive film on the sensing properties of these devices were investigated. The gas sensitive performances of these devices in response to analytes were compared. Among them, the sensing devices fabricated using original and acidic solutions of porphyrin exhibited significant responses to sulfide gases and ethanediamine, respectively. The sensing device prepared using an acidic solution has a good response to ethanediamine gas (response and recovery times of the sensor for 1 ppm of EDA (ΔI = 48) are 13 and 38 s, respectively). The RSD of the output light intensity is ±2.84, the signal to noise ratio (S/N) is 5.6. The device prepared using the original solution has an excellent response to sulfide gases (H 2 S, SO 2 ), and can detect low concentration levels (ppm) of sulfide gases. These sensing devices thus have the potential to be used in food quality testing and environmental monitoring.
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MICROPOROUS AND MESOPOROUS MATERIALS
·
2020
·
IF 4.551
Fangbin Fan,Xiaobin Nie,Chao Fan,Xiaojing Liang,Xiaofeng Lu,Yong Guo
In this paper, L (+)-Cysteine (L-Cys) and 5-norbornene-2-carboxylic acid (5-N-2-CA) were modified on the silica spheres by cross-linking polymerization and thiol-ene click reaction. The Cys-Si-NCA was characterized by scanning electron microscopy, nitrogen sorption porosimetry , thermogravimetric analysis and other characterization methods. The results indicated that the colume had a regular spherical shape with porous surfaces and particle sizes mainly ranging from 4.5 to 5.5 μm. The surface area of the Cys-Si-NCA microspheres was 328.68 m 2 g −1 , and their respective average pore size was 9.27 nm. Furthermore, the colume exhibited excellent stabilities and reproducibility. Experimental results demonstrate that this new stationary phase can facilitate the separation of sulfonamides, nucleosides and nucleobases compounds in hydrophilic chromatographic (HILIC) conditions. In addition to being able to attenuate the peak tailing of separation, it can also be used for quantitative analysis of creatinine in urine. We also give the temperature and pH ranges of separation on Cys-Si-NCA column. The successful synthesis of the Cys-Si-NCA stationary phase provides foundation for the application of this kind of materials in liquid chromatography (LC).
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ChemCatChem
·
2020
·Vol. 12
·期 15
·3880-3889
·
IF 4.853
Xingling Zhao,Jun Xu,Yueying Chu,Guodong Qi,Qiang Wang,Wei Gao,Shenhui Li,Ningdong Feng,Feng Deng
Graphical Methane activation : Different types of Ga-CH 3 species were observed in methane activation on Ga-modified ZSM-5 zeolite, evidencing different pathways for heterolytic cleavage of C−H bond of methane. Two-dimensional solid-state NMR experiments provided detailed information on the location and local environment of the Ga-CH 3 species. Methane activation on Ga-modified ZSM-5 zeolites (Ga/ZSM-5) was studied by solid-state NMR spectroscopy. Two types of Ga species, namely highly dispersed oxides and cationic Ga species, were determined by 71 Ga QCPMG NMR. The activation of methane on Ga/ZSM-5 was explored by using 13 C and 1 H MAS NMR. Four types of Ga-CH 3 species along with Ga-OH groups were observed on Ga/ZSM-5, evidencing different pathways for heterolytic cleavage of C−H bond of methane. Two-dimensional (2D) 1 H- 1 H correlation NMR experiments provide detailed information on the location and local environment of the Ga-CH 3 species by correlating the protons in Ga-CH 3 with those in Ga-OH and other hydroxyls on zeolite. The structures of different Ga-CH 3 species were further determined by 2D 1 H- 13 C heteronuclear correlation NMR experiments, which were supported by theoretical calculations. The activation routes of C−H bond in methane were proposed on Ga/ZSM-5 zeolite.
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INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
·
2020
·
IF 3.573
Tengjiao He,Yonghou Xiao,Qidong Zhao,Mengxue Zhou,Gaohong He
Separation of carbon dioxide (CO2) from a CO2/ethylene (C2H4) mixture represents an important and challenging field in industrial applications. Selective adsorption has become an attractive option as an energy-saving and environmentally friendly CO2 capture technology. In this work, an ultramicroporous metal–organic framework (MOF) Qc-5-Cu was prepared by solution method and applied for the highly selective separation of CO2 from an C2H4 stream. The performance of Qc-5-Cu was evaluated by static and dynamic adsorption experiments. It was found that the single-component adsorption capacities of CO2 and C2H4 on Qc-5-Cu at 298 K and 1 bar were 2.48 and 0.74 mmol/g, respectively. The measured breakthrough curves further illustrate that Qc-5-Cu could effectively separate CO2 from the C2H4 stream for more than 10 cycles. The pore size of the obtained Qc-5-Cu was ∼3.3 Å, as characterized by nitrogen adsorption. The ultramicroporous structure of Qc-5-Cu benefits the separation of CO2, as evidenced by the selectivity values of the CO2/C2H4 binary mixture (1:99, v/v) based on the ideal adsorbed solution theory (SIAST ≈ 39.95 avg.), which are larger than some MOFs with open metal sites, owing to the weak interaction between organic ligands with high aromaticity and C2H4, as well as the porous screening effect of Qc-5-Cu on ethylene. The observed high selectivity, excellent stability, and regeneration performance demonstrate that Qc-5-Cu is a promising adsorbent for the separation of the CO2/C2H4 mixture.
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Nanoscale
·
2020
·Vol. 12
·期 6
·3846-3854
·
IF 6.895
Xiao Xiao,Shuang Liang,Yajie Zhao,Dayu Huang,Bengang Xing,Ziyong Cheng,Jun Lin
High treatment efficiency and low drug toxicity are two key factors in tumor therapy. The development of multifunctional drug carrier systems is of great significance for the diagnosis and therapy of tumors. Herein, a novel biodegradable treatment system based on zeolitic imidazolate framework-90 (ZIF-90) was designed in this study. This 5-FU@ZIF-90@ZnO (FZZ) drug delivery system achieves synergistic treatment with antineoplastic 5-fluorouracil (5-FU) and zinc oxide, and also has good dispersibility in the acidic tumor microenvironment (TME), which enables the drug to achieve pH-controlled delivery in acidic organisms. Interestingly, zinc oxide nanoparticles can play a dual role here. They can prevent the premature leakage of drugs under physiological conditions. Moreover, Zn2+ produced after the decomposition of nanoparticles can act as a therapeutic agent, overcoming the tumor resistance to 5-FU and regulating a series of physiological reactions to inhibit tumor growth. It is worth noting that the porous ZIF-90 is an emerging drug carrier with a relatively high drug loading rate of 39% in this study. Synergistic 5-FU and ZnO nanoparticles have achieved tumor inhibition and have shown high therapeutic biosafety. Thus, the FZZ core–shell nanoparticles are a potential pH-controlled drug release system that can be applied to tumor treatment.
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