INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jing Peng,Qiyue Xiao,Jieyu Xue,Yijia Cao,Jiayi Chen,Jingwen Zhao,Yuanrong Ding,Xuhong Yang,Yong Yang
As modern industry continues to advance, noise pollution is becoming increasingly severe, posing a significant threat to the global economy and human health. Given their porous structure and lightweight properties, aerogels exhibit substantial potential in the field of acoustics. Concurrently, the use of environmentally-friendly, biodegradable materials such as chitosan (CS) and polyvinyl alcohol (PVA) not only helps address environmental challenges but also contributes to reducing pollution. This study investigates the microstructural evolution of CS/PVA aerogels through compositional tuning, aiming to significantly enhance their acoustic properties. Through meticulous adjustment of the CS and PVA concentrations during the sol-gel process, we successfully fabricated aerogels with a remarkable low density of 0.0240 g·cm −3 and a high porosity of 98 %. The resulting aerogels demonstrate exceptional acoustic performance, with a sound transmission loss (STL) exceeding 20 dB in the frequency ranges of 450 to 1000 Hz and greater than 3000 Hz, and a noise reduction coefficient (NRC) of 0.428 at a thickness of only 18 mm. In addition, CS/PVA aerogel also exhibits certain thermal insulation properties, with a minimum thermal conductivity of 0.0387 W·m −1 ·K −1 . These findings underscore the potential of CS/PVA aerogels as low-density and environment friendly acoustic materials.
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高影响因子
Discover Food
·
2025
·Vol. 5
·期 1
·1-15
·
IF 3.7
Tian Zhen,Jin Huaizhou,Shang Xiaoxiao,Ma Qifei,Wang Weihong,Jin Shangzhong
The long-term stability of Pickering emulsions is crucial for their application in food systems. This study aimed to evaluate the stability degradation of oil-in-water (O/W) Pickering emulsions stabilized by whey protein isolate (WPI) and chitosan (CS), and to assess their applicability in reduced-fat mayonnaise formulations. Optical tweezers were employed to quantify the interaction forces between emulsion droplets during storage, in combination with microstructural observation and ζ-potential analysis. It was found that the O/W emulsion prepared with a 50% aqueous phase volume fraction maintained a stable droplet size over the storage period without significant changes. The ζ-potential decreased from 79.16 mV to 53.62 mV, while the maximum droplet contact force gradually decreased from 69 pN to 37 pN by day 45. By day 60, droplet coalescence was observed. Compared with traditional rice bran oil mayonnaise, the mayonnaise formulated using this Pickering emulsion exhibited superior mechanical stability and resistance to destabilization. In particular, the formulation with a Pickering emulsion-to-egg yolk volume ratio of 4:1 showed the best mechanical performance, with the droplet contact force gradually decreasing from 68 pN on day 0 to 62 pN on day 20. This study provides a rapid method for evaluating the stability of food systems, offering potential applications in the food industry.
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MATERIALS & DESIGN
·
2025
·
IF 7.9
Wenxuan zhao,Yuzhe Chen,Xiaopei Wu,Xianzheng Dong,Honglian Dai
Peripheral nerve injury repair is hindered by an imbalanced regenerative microenvironment involving inflammation, oxidative stress, and inadequate blood supply. Traditional drugs are limited by poor blood-nerve barrier penetration and lack of multifunctionality. Nitric oxide (NO) is crucial for axonal growth, synaptic plasticity, and neuroprotection, offering anti-inflammatory, antioxidant and pro-angiogenic potential. However, uncontrolled NO release causes toxicity. To leverage NO therapeutically, sustained delivery is essential. This study developed a multifunctional nerve graft using a modified chitosan hydrogel grafted with RGDC peptide, featuring an internal orientation microstructure. Glutathione was incorporated as a precursor for the NO donor S-nitrosoglutathione (GSNO). This system promotes cell adhesion/migration and reduces oxidative stress. Results show the hydrogel is non-cytotoxic and synergistically enhances cellular adhesion. GSNO loading significantly reduces cellular reactive oxygen species (ROS) levels in human umbilical vein endothelial cells (HUVECs), facilitating their migration and angiogenesis. The GSNO-incorporated neural scaffold achieved sustained NO release and demonstrated significant antioxidant capacity. This innovative approach presents a promising strategy for clinical application in peripheral nerve injury repair.
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DESALINATION
·
2025
·
IF 9.8
Yimin Qu,Changliang Lu,Gaofeng Zhang,Zhu Hu,Dajian Huang,Xiaohu Qiang,Yanping Wang
With the escalating global water crisis, solar-driven interfacial evaporation has garnered significant attention as a sustainable desalination technology. However, it still faces challenges such as low evaporation efficiency, salt accumulation, and insufficient durability under real-world conditions. To address these issues, this study used chitosan (CTS) as a matrix to disperse carbon nanotubes (CNTs) with the assistance of palygorskite (Pal). The resulting Pal-CNTs composites were incorporated into the CTS matrix to prepare high-performance aerogels aimed at enhancing solar interfacial evaporation efficiency. The results show that Pal effectively prevents CNT aggregation, enabling uniform dispersion within the CTS matrix and resulting in enhanced light absorption and thermal management. Inspired by the multichannel structure of plant xylem, CTS/Pal/CNTs composite aerogels (CPC) with vertical pores were fabricated using directional freeze-drying. The combination of superhydrophilicity imparted by CTS and Pal, along with the vertical pore structure, allows the CPC to efficiently store and transport water. The CPC can produce up to 13.1 kg m −2 of water per day in outdoor conditions. Moreover, the vertical pore architecture and continuous water supply enable rapid salt diffusion, effectively resisting salt crystallization and maintaining stable performance even in high-salinity brine. The resulting solar evaporator also demonstrates robust mechanical strength and long-term stability, showing great potential for practical freshwater production.
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Biomaterials Science
·
2025
·
IF 5.7
Zhenxing Han,Ting Wang,Ruotong Ma,Mariem Elmalkig,Siyu Cheng,Chuang Li,Dandan Li,Zhenglian Xue,Guangjun Nie
Noncovalent chitosan (CS)/hyaluronic acid (HA) hydrogel has been characterized by favorable cytocompatibility, biodegradability and non-toxicity. It bears a close resemblance to human skin and holds promising potential applications in medical engineering. Nevertheless, the CS/HA hydrogels have yet to achieve widespread application due to the relatively weak toughness. In this study, salts were utilized to regulate the mechanical properties of CS/HA hydrogel. The results indicated that copper nitrate was the most effective regulator, which transformed intramolecular hydrogen bonds and electrostatic interactions into intermolecular hydrogen bonds and cation chelations, respectively. The regular domains in the hydrogel were reduced while the crosslink was strengthened. Consequently, the toughness of the hydrogel was increased to 7.8 MJ/m3, 1253-fold that of covalent CS/HA hydrogel. The salt effect was replicated in the other two hydrogels, attesting to its generality. Hence, salt regulation proves to be an effective way to enhance mechanical properties of hydrogel. In addition, the copper nitrate-regulated hydrogel exhibited favorable drug delievring behavior and photothermal response. Under the exposure of near-infrared light, the release rate and amount of the drug loaded in the hydrogel were increased by 40% and 39% respectively within 20 minutes, manifesting a remarkable potential for application as a drug carrier.
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LANGMUIR
·
2025
·
IF 3.9
Yuan Bai,Xinyu Gan,Zongxian Jing,Pengfei Fan
The development of efficient and environmentally sustainable adsorbents for dye removal from wastewater remains a significant environmental challenge. Azo dyes, such as methyl orange (MO), persist in aquatic environments due to their high chemical stability and resistance to biodegradation. Although chitosan-based materials have been extensively studied for dye adsorption, their low solubility, poor mechanical stability, and limited adsorption capacity restrict large-scale applications. In this study, sulfonated chitosan/graphene oxide (SCSGO) and N,O-carboxymethyl chitosan/graphene oxide (N,O-CMCSGO) were synthesized and evaluated for MO adsorption. SCSGO and N,O-CMCSGO exhibit high MO adsorption capacities (265.67 and 239.60 mg/g, respectively), with Freundlich isotherm modeling confirming multilayer adsorption on heterogeneous surfaces via combined electrostatic, hydrogen bonding, and π–π interactions. Kinetic analysis indicates nonspontaneous adsorption controlled by external and intraparticle diffusion. FTIR and XPS analyses confirm that functionalization alters the surface chemistry, enhancing the MO affinity. Notably, after five consecutive adsorption–desorption cycles, SCSGO maintains over 90% of its original adsorption efficiency.
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Materials Chemistry Frontiers
·
2025
·
IF 6.4
QiHang Bu,ZeiFeng Yue,ZiHan Wang,Ning Jiang,Haibo Luo,RongXue Sun,QianYuan Liu,JianHua Xu,Cheng Wang,JiaJun Fu
Given the environmental problems caused by petroleum-based packaging materials, there is an urgent requirement for the development of sustainable bio-based green active packaging materials. Despite this need, the practical application of bio-based polymers, such as chitosan and cellulose, is limited due to their poor mechanical properties and barrier properties. Here, we prepared a novel chitosan-based green active composite film, employing chitosan nanoparticles encapsulating gallic acid as nanofillers. The interfacial interactions between the nanoparticles and chitosan matrix were found to significantly enhance the mechanical properties and barrier properties of the composite film. Moreover, the integration of gallic acid-loaded nanoparticles substantially improved the antimicrobial and antioxidant activities of the composite film. These improvements are crucial for inhibiting the proliferation of food-borne microorganisms and the oxidation of lipids, thereby preserving the quality and safety of foods. Freshness preservation experiments have demonstrated that this composite film could effectively mitigate the quality degradation of crayfish meat during storage, thereby verifying its potential application in the field of food packaging. Consequently, this sustainable bio-based green active packaging film has the potential to replace the traditional petroleum-based packaging film and inspires the development of new sustainable bio-based active packaging films.
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RSC Advances
·
2024
·Vol. 14
·期 21
·15021-15030
·
IF 3.9
Jingxuan Liu,Hongyu Zhao,Mengyue Wang,Wenzheng Ban,Xi Lu,Bin Yan
In this work, gallic acid was successfully grafted onto quaternary aminated chitosan to prepare a high efficiency cationic flocculant. The mechanism of flocculation and different influencing factors were studied in detail. The prepared flocculant only needs 60 mg L−1 to achieve a 98.7% and 94.5% removal rate on methyl blue (MB) and Congo red (CR), respectively. The high removal rate (93.2%) of a CR-MB mixed dye also confirms the universality of flocculation. In addition, kaolin as a simulated suspended solid was removed at a rate of 97% in the experiment at a dosage of 3 mg L−1. A zeta potential test showed that it worked best when the potential of the flocculation system was zero; this was because an electrostatic balance was reached between the flocculant and pollutant. Importantly, the three-functional molecules can provide more possibilities to form hydrogen bonds with water molecules, which is conducive to the stretching of flocculant molecular chains in salt water. The flocculant maintained a high stability in four different salt environments and has a positive industrial application significance. Furthermore, the flocculation experiment of the actual wastewater of the printing and dyeing plant found that the dye wastewater changed obviously from turbidity to clarification, which proved the practical application potential of the flocculant. This work provides a feasible idea for the preparation of bio-based flocculants.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Yuyang Cao,Duoling Xu,Zhaoji Zu,Genlu Xu,Yixi Zeng,Jiyu Weng,Zhenhai Huang,Hongping Xiang,Lanyue Zhang,Jinlong Ding,Hui Li
Thermosensitive hydrogels show great potential in healing diabetic wounds, but they are still challenged by the long healing time, risk of infectivity, and accumulation of melanin. Herein, a dual network hydrogel is designed, which consists of chlorogenic acid (CA) modified chitosan (CS) (CA@CS), poly(N-isopropylacrylamide) (PNIPAm), and glabridin liposomes (GL). The gelation transition temperature of the hydrogel is 32–34 °C, which thus endows it with superior injectability at ambient temperature. Moreover, GL/PNIPAm/CA@CS also exhibits excellent biocompatibility, and can promote the growth of epidermal cells, and the healing of diabetic wounds. GL/PNIPAm/CA@CS can also control the immune reactions by enhancing the release of CD206, and decreasing the formation of CD86 and ROS, which further promotes the production of CD31 and VEGF, and reduces the expression of pro-inflammatory factors, thus aiding in the healing of diabetic wounds. Furthermore, GL/PNIPAm/CA@CS can also suppress the growth bacterial, which can thus decrease the wound microbiota levels and facilitate the recovery of diabetic wounds. More importantly, it can reduce melanin production by 80 % due to the action of glabridin. Consequently, GL/PNIPAm/CA@CS shows significant promise in enhancing the wound healing in future and decreasing the accumulation of melanin.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
·
IF 7.7
Zhiying Shao,Xiaoyi Jiang,Qinlu Lin,Simiao Wu,Siming Zhao,Xinyang Sun,Yunhui Cheng,Yong Fang,Peng Li
The presence of potentially toxic elements and compounds poses threats to the quality and safety of fruit juices. Among these, Hg(II) is considered as one of the most poisonous heavy metals to human health. Traditional chitosan-based and selenide-based adsorbents face challenges such as poor adsorption capacity and inconvenient separation in juice applications. In this study, we prepared nano‑selenium functionalized chitosan gel beads (nanoSe@CBs) and illustrated the synergistic promotions between chitosan and nanoSe in removing Hg(II) from apple juice. The preparation conditions, adsorption behaviors, and adsorption mechanism of nanoSe@CBs were systematically investigated. The results revealed that the adsorption process was primarily controlled by chemical adsorption. At the 0.1 % dosage, the adsorbent exhibited high uptake, and the maximum adsorption capacity from the Langmuir isotherm model could reach 376.5 mg/g at room temperature. The adsorbent maintained high adsorption efficiency (> 90 %) across a wide range of Hg(II) concentrations (0.01 to 10 mg/L) and was unaffected by organic acids present in apple juice. Additionally, nanoSe@CBs showed negligible effects on the quality of apple juice. Overall, nanoSe@CBs open up possibilities to be used as a safe, low-cost and highly-efficient adsorbent for the removal of Hg(II) from juices and other liquid foods.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Shaohui Guo,Minxuan Yang,Zhilang Xu,Liming Ge,Changdao Mu,Defu Li
Guided bone regeneration (GBR) technique is a standard therapy for reconstructing alveolar bone defects clinically, with the GBR membrane serving as the key medical device in this technique. However, the most commonly used collagen barrier membranes usually have poor mechanical properties and are prone to collapse during clinical use. Herein, a sandwich-like barrier membrane was developed with crosslinked chitosan as dense layer, crosslinked collagen as loose layer and passivated magnesium mesh as the skeleton. Surface modification has improved the corrosion resistance of magnesium mesh. Thanks to the introduction of magnesium mesh skeleton and crosslinking modification, the mechanical properties and supporting effects of barrier membrane have been improved. The dense layer of barrier membrane showed dense structure while the loose layer showed porous structure as expected. The barrier membrane showed good antibacterial performance against gram-positive and gram-negative bacteria owing to the antibacterial activity of chitosan and the added chlorhexidine acetate. Furthermore, the barrier membrane met the requirements of biocompatibility for implanted biomaterials. Interestingly, the barrier membrane had good anti-inflammatory activity to accelerate the transition from inflammatory to proliferative stage and can promote osteogenic differentiation of MC3T3-E1 cells. Overall, the sandwich-like barrier membrane has a wide application prospect to guide bone regeneration.
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CELLULOSE
·
2024
·Vol. 31
·期 7
·4291-4303
·
IF 4.9
Xu Diansheng,Yang Jinshan,Lou Tao,Wang Xuejun
To improve the selective adsorption of the target pollutant, this study successfully synthesized chitosan/carboxymethyl cellulose molecularly imprinted hollow vesicles (CS/CMC-MIV) for selective adsorption of acid blue-113 (AB-113). The vesicles were obtained by mixing the carboxymethyl cellulose solution with the chitosan/AB-113 mixture in sequential fast and slow stirring. Benefiting from the molecular imprinting technique, the maximum adsorption capacity of AB-113 by CS/CMC-MIV was 972.7 mg/g, which was 84.8% higher than that of the vesicles without imprinting (526.4 mg/g). The adsorption process could be well in accordance with Langmuir isotherm and pseudo-second-order models. The vesicles exhibited superior stability and reusability, maintaining 92% of the initial adsorption capacity after four adsorption repeats. What's more, CS/CMC-MIV showed excellent selective adsorption ability on mixed dye solutions, which was attributed to the specific recognition sites created during the molecular imprint process. This study provides a facile method to bind dye templates to vesicles and excels at selective dye removal.
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危险品化学品经营许可证（带存储）