JOURNAL OF FOOD SCIENCE
·
2021
·Vol. 86
·期 8
·3550-3562
·
IF 3.167
Ying Cai,Jingwei Guan,Wen Wang,Li Wang,Jianyu Su,Liming Fang
Food packaging materials, especially biodegradable polymer composites incorporated with natural antimicrobial agents with excellent antibacterial activities, are in high demand and attracted immense attention. Herein, a polycaprolactone/curcumin@zeolitic imidazolate framework-8 (PCL/Cur@ZIF-8) composite film with enhanced antibacterial activity was developed. Curcumin, a natural photosensitizer, was loaded in the highly porous nanocrystals ZIF-8 to improve its poor water solubility and stability. The integral structure of Cur@ZIF-8 was maintained well in the PCL matrix even at the highest loading of 35% (w/w), and all composite films had good light transmittance at 420–430 nm. The PCL/Cur@ZIF-8 composite films responded to the acidic growth environment of bacteria by releasing zinc ions and curcumin molecules. Furthermore, upon blue light irradiation (420–430 nm, 2.2 mW/cm 2 ), curcumin molecules generated singlet oxygen. With the synergistic effects of zinc ions and singlet oxygen, the composite films exhibited a 99.9% reduction of Escherichia coli and Staphylococcus aureus strains when the amount of Cur@ZIF-8 loading was more than 15% (w/w), as well as a strong anti-adhesion effect on bacteria. Moreover, bacterial resuscitation tests indicated that the composite films exhibited 99.9% reduction in the adhered bacteria population through treatment with photodynamic sterilization. This is the first study presenting that the incorporated curcumin ZIF-8 nanoparticles in the matrix of polymer are pH and light responsive for anti-adhesion of bacteria, which is of great potential application as antibacterial packaging material for the food industry. Practical Application A novel, biodegradable, pH, and light-responsive composite film was developed for antibacterial activity. Natural photosensitizer curcumin was encapsulated in ZIF-8 nanocrystals (Cur@ZIF-8) as the antimicrobial agent. With the synergistic effects of Zn 2+ and singlet oxygen, the composite film exhibited a 99.9% reduction of Escherichia coli and Staphylococcus aureus strains, and a strong anti-adhesion property toward bacteria. This composite film is of great potential application as an antibacterial packaging material that enhances the shelf life of fruits, meat, and so on.
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DOI
高影响因子
Water Cycle
·
2021
·
IF 0
Yuwei Pan,Zhujun Dong,Yi Pan,Yizhen Zhang
In this study, nitrilotriacetic acid (NTA) was used to enhance UV/Fe 0 /H 2 O 2 process for highly salty wastewater at neutral pH. The addition of Fe 0 could not accelerate the UV/H 2 O 2 process for salty wastewater treatment at neutral pH due to the precipitation of Fe ions. While NTA added into UV/Fe 0 /H 2 O 2 process which could form complex with Fe ion, the tartrazine removal could increase from 45.7% to 84.7% within 60 min. The k -value of the UV/Fe 0 -NTA/H 2 O 2 system to remove tartrazine is also 2.2 times higher than that in UV/Fe 0 /H 2 O 2 system. Meanwhile, the UV/Fe 0 -NTA/H 2 O 2 process could obtain good performance for salt wastewater treatment under a wide salt concentration level of 0–0.2 M. It can also expand the application range of pH to neutral pH. SEM and XPS characterization showed that the corrosion rate of Fe 0 in salty system was faster, and the presence of NTA could accelerate the recirculation of Fe 3+ /Fe 2+ on the Fe 0 surface. EPR spectroscopic analysis and scavenge experiments showed that • OH was the main reactive radical for the removal of tartrazine in the UV/Fe 0 -NTA/H 2 O 2 system. In addition, the k -value for removing tartrazine in various types of salt systems in the UV/Fe 0 -NTA/H 2 O 2 system was 3.2–4.2 times that of the UV/Fe 0 /H 2 O 2 system. It demonstrated UV/Fe 0 -NTA/H 2 O 2 processes fits to different types of salt system. Therefore, this study will provide a new method for the treatment of saline wastewater at neutral pH.
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ACS Omega
·
2021
·
IF 3.512
Yaqi Gong,Shabbir Mohd,Simei Wu,Shilin Liu,Ying Pei,Xiaogang Luo
Functional modified cellulose microsphere (CMs) materials exhibit great application potential in drug various fields. Here, we designed pH-responsive carboxylated cellulose microspheres (CCMs) by the citric/hydrochloric acid hydrolysis method to enhance oral bioavailability of insulin by a green route. The CMs were high purity cellulose that dissolved and regenerated from a green solvent by the green sol–gel method. The prepared microspheres were characterized by spectroscopic techniques, such as field emission scanning electron microscopy (FE-SEM), Fourier transform infrared spectrum (FT-IR), X-ray diffraction (XPS), etc. The spherical porous structure and carboxylation of cellulose were confirmed by FESEM and FT-IR, respectively. Insulin was loaded into the CCMs by electrostatic interactions, and the insulin release was controlled through ionization of carboxyl groups and proton balance. In vitro insulin release profiles demonstrated the suppression of insulin release in artificial gastric fluid (AGF), while a significant increase at artificial intestinal fluid (AIF) was observed. The insulin release profile was fitted in Korsmeyer–Peppas kinetic model, and insulin release was governed by the Fickian diffusion mechanism. The stability of the secondary structure of insulin was studied by dichroism circular. Excellent biocompatibility and no cytotoxicity of designed CCMs cast them as a potential oral insulin carrier.
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高影响因子
ACS Applied Energy Materials
·
2024
·
IF 5.4
Weihao Wang,Qin Liu,Hong Zhang,Lianmeng Cui,Bomian Zhang,Baokang Niu,Ahmed Eissa Abdelmaoula,Chunhua Han,Lin Xu
The concentrated hydroxide ions (OH–) resulting from the hydrogen evolution reaction gives rise to substantial challenges for the Zn anode/electrolyte interface, including proliferating byproducts and severe dendrite growth. Herein, methyl acetate (MA) additive is proposed to eliminate the crippling OH–, hence manipulating interfacial pH and alleviating accumulation of byproducts. Raman spectra and FTIR analysis elucidate the underlying mechanism of the hydrolysis reaction, which means attacked carbonyl corresponding to the elimination of OH–. In situ pH monitoring verifies availably inhibited OH– concentration with MA additive. From multidimension analysis, the base-catalyzed hydrolysis strategy can significantly protect Zn anode from deterioration during “shelf life” contributing to following superior Zn plating/stripping. Consequently, with MA additive, the pH is stabilized at a lower level of 5.11. Zn plating/stripping achieves a conspicuous cycle life of 2000 h (2.0 mA cm–2 with 2.0 mA h cm–2). Even after “shelf life”, Zn||Zn symmetric cells deliver an impressive cycling stability of 700 h compared to the counterpart of 22 h in ZnSO4. Zn||MnO2/CNT pouch cells with a high mass loading cathode of ∼8 mg cm–2 exhibit a stable lifespan of 100 cycles at 1 C. This work demonstrates a hydrolysis strategy to manipulate interfacial pH and stabilize the interface for the reversible Zn anode.
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高影响因子
ACS Sustainable Chemistry & Engineering
·
2017
·
IF 5.951
Yanjun Gong,Yongxian Guo,Qiongzheng Hu,Chen Wang,Ling Zang,Li Yu
Keggin-type polyoxometalate (POM), phosphotungstic acid (H3PW12O40), was encapsulated by an oppositely charged COOH-functionalized surface active ionic liquid (SAIL), N-decyl-N′-carboxymethyl imidazolium bromide ([N-C10, N′-COOH-Im]Br), with the assistance of an ionic self-assembly (ISA) process in an aqueous environment. The as-prepared POM/SAIL material possesses multiple active properties, including reversible pH-response and renewable catalyst for dye degradation. Specifically, the POM-based hybrid materials show a great enhancement in catalytic efficiency when it is employed in degradation of methyl orange (MO) in aqueous solution. Furthermore, the electrostatic repulsions between POM and the deprotonated SAIL may result in the pH-induced disassembly and assembly of the hybrid nanomaterials, which provides an expedient method to regenerate the catalytic activity. Therefore, the presented POM/SAIL hybrid materials are expected to improve the common poisoning issue of the traditional heterogeneous catalysts for industrial applications.
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高影响因子
Frontiers of Materials Science
·
2018
·Vol. 12
·期 2
·118-128
·
IF 1.478
Wang Qian,Meng Guihua,Wu Jianning,Wang Yixi,Liu Zhiyong,Guo Xuhong
We fabricated pH and light dual-responsive adsorption materials which could induce the transition of surface wettability between hydrophobicity and hydrophilicity by using ATRP. The structure and morphology of adsorption materials were confirmed by ATR-FTIR, XPS, TGA and SEM. It showed that the modified cellulose (CE)-based foam was hydrophobic, which can adsorb a range of oils and organic solvents in water under pH = 7.0 or visible light irradiation ( λ > 500 nm). Meanwhile, the wettability of robust CE-based foam can convert hydrophobicity into hydrophilicity and underwater oleophobicity under pH = 3.0 or UV irradiation ( λ = 365 nm), giving rise to release oils and organic solvents. Most important of all, the adsorption and desorption processes of the modified CE-based foam could be switched by external stimuli. Furthermore, the modified CE-based foam was not damaged and still retained original performance after reversible cycle repeated for many times with variation of surface wettability. In short, it indicates that CE-based foam materials with switchable surface wettability are new responsive absorbent materials and have owned potential application in the treatment of oil recovery.
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高影响因子
NANO
·
2021
·
IF 1.556
Wenlong Li,Weiwei Zhang,Weihao Jin,Longbao Zhu,Wanzhen Li,Ping Song,Yugui Tao,Fei Ge
Design of high-performance drug delivery system is necessary to improve the anticancer ability of 5-fluorouracil (5-FU). In this work, we developed a pH-responsive 5-FU loaded and sodium alginate (SA) modified mesoporous silica nanoparticles (MSNs) drug delivery system (5-FU@MSN-SA). After 5-FU was loaded into the pores, MSNs were successfully functionalized with amino groups and then capped by sodium alginate. Compared to acidic conditions, the drug release rate in the neutral environment was quite low. Moreover, detailed investigations confirmed that 5-FU@MSN-SA can easily be up-taken by cancer cells and proved the high cytotoxicity to 4T1 cells. The calculated IC 5 0 values for 5-FU and 5-FU@MSN-SA were 34.67 μ g/mL and 54.95 μ g/mL, respectively. These results indicated that 5-FU@MSNs-SA can be a promising nanoplatform in cancer therapy.
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高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2019
·
IF 3.131
Hui Zhao,Ying Li
Tremella polysaccharide , a novel polysaccharide , not only has good ability of film forming, but also has excellent physiological functions, which was suitable to be used to prepare eco-friendly hydrogels. In this study, a novel pH/temperature responsive micelle-laden hydrogel based on tremella polysaccharide (WSK), carboxymethyl cellulose (CMC) and nonionic surfactant-decyl polyglucoside (C 10 APG) was fabricated through radical polymerization by crosslinking N-isopropylacrylamide (NIPAM), for the purpose to achieve controlled release of hydrophobic drugs indomethacin (IND). Firstly, WSK/CMC/PNIPAM hydrogels were prepared and their characteristics were investigated by FTIR, TGA , SEM, rheological and compressive tests as well as swelling experiments. Then the hydrophobic drug IND molecules were solubilized in C 10 APG micelles which were uniformly dispersed in the WSK/CMC/PNIPAM/C 10 APG networks. Lastly, the IND release behavior of WSK/CMC/PNIPAM/C 10 APG hydrogels was studied, which exhibited both pH and temperature sensitivity. The obtained WSK/C 10 APG-based pH/temperature sensitive hydrogel may have potential in biomedical applications such as drug vehicles and tissue engineering.
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高影响因子
Journal of Materials Chemistry A
·
2022
·Vol. 10
·期 15
·8364-8370
·
IF 14.511
Qiqi Mao,Kai Deng,Wenxin Wang,Peng Wang,You Xu,Ziqiang Wang,Xiaonian Li,Liang Wang,Hongjing Wang
Porous Pd-based metallene with highly curved, ultrathin and porous architectural features is a promising candidate for the hydrogen evolution reaction (HER), and structural design and component modification can effectively enhance its performance. Herein, we present a powerful approach to boost the HER performance of porous PdIr bimetallene through N-doping, which can effectively modulate the electronic structure and induce the strain effect of the designed N-doped porous PdIr bimetallene (N-PdIr bimetallene). The porous N-PdIr bimetallene exhibits superior all-pH HER activity and stability. To generate a cathodic current density of 10 mA cm−2, the required overpotential for the porous N-PdIr bimetallene is 26, 34 and 59 mV in 0.5 M H2SO4, 1 M KOH and 1 M phosphate buffer solution (PBS), respectively, which outperform those of commercial Pt/C. The proposed N-doping approach is a very powerful strategy for boosting metallene electrocatalytic performance, beyond the HER.
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高影响因子
Asian Journal of Pharmaceutical Sciences
·
2022
·
IF 9.273
Yanjuan Huang,Hualu Lai,Jingwen Jiang,Xiaoyu Xu,Zishan Zeng,Lingling Ren,Qiuxing Liu,Meixu Chen,Tao Zhang,Xin Ding,Chunshun Zhao,Shengmiao Cui
Photodynamic therapy (PDT)-mediated oxidation treatment is extremely attractive for skin melanoma ablation, but the strong hydrophobicity and poor tumor selectivity of photosensitizers, as well as the oxygen-consuming properties of PDT, leading to unsatisfactory therapeutic outcomes. Herein, a tumor acidic microenvironment activatable dissolving microneedle (DHA@HPFe-MN) was developed to realize controlled drug release and excellent chemo-photodynamic therapy of melanoma via oxidative stress amplification. The versatile DHA@HPFe-MN was fabricated by crosslinking a self-synthesized protoporphyrin (PpIX)-ADH-hyaluronic acid (HA) conjugate HA-ADH-PpIX with “iron reservoir” PA-Fe 3+ complex in the needle tip via acylhydrazone bond formation, and dihydroartemisinin (DHA) was concurrently loaded in the hydrogel network. HA-ADH-PpIX with improved water solubility averted undesired aggregation of PpIX to ensure enhanced PDT effect. DHA@HPFe-MN with sharp needle tip, efficient drug loading and excellent mechanical strength could efficiently inserted into skin and reach the melanoma sites, where the acidic pH triggered the degradation of microneedles, enabling Fe-activated and DHA-mediated oxidation treatment, as evidenced by abundant reactive oxygen species (ROS) generation. Moreover, under light irradiation, a combined chemo-photodynamic therapeutic effect was achieved with amplified ROS generation. Importantly, the Fe-catalyzed ROS production of DHA was oxygen-independent, which work in synergy with the oxygen-dependent PDT to effectively destroy tumor cells. This versatile microneedles with excellent biosafety and biodegradability can be customized as a promising localized drug delivery system for combined chemo-photodynamic therapy of melanoma.
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高影响因子
ACS Applied Bio Materials
·
2023
·
IF 4.7
Hui Zhi,Fengya Wang,Xiaobo Zhang,Qinxin Cai,Meng Chen,Yushu Shi,Liang Feng
Traditional hydrogel dressings generally have poor mechanical properties and stability when subjected to external stress due to the undesirable chain entanglement structure of their single valence bond compositions. Therefore, it is particularly important to develop a type of gel dressing with good mechanical strength, stability, and environment-friendly monitoring. In this work, a transparent, pH-sensitive, highly stretchable, and biocompatible anthocyanidin ionogel dressing was prepared, realizing green and accurate detection. Attributed to the antibacterial activity of the ionic liquid, the biocompatibility of the pectin, and the ability to scavenge free radicals of the anthocyanidin, the ionogel dressing exhibited excellent re-epithelialization in the 14 day wound healing process. Besides, changes in pH values monitoring of the ionogel over 3 days coincided with normal wound exudate. The obtained ionogel also showed good water retention, swelling properties, mechanical stretchability, and 5 week stability, illustrating great potential in wound dressings.
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高影响因子
TEXTILE RESEARCH JOURNAL
·
2022
·
IF 2.455
Xun Zhang,Sarkodie Bismark,Zhifeng Zhu
Tertiary amine groups can exhibit and lose cationic properties at different pH levels, and this group can be introduced to starch chains to satisfy the demand for sizing and desizing. However, the effect of pH on tertiary amine groups in toughening starch film and improving adhesion is still unclear. Therefore, 2-dimethylaminoethyl starch (DMAES) was prepared via tertiary aminated starch with 2-dimethylaminoethyl chloride hydrochloride. The influences of pH on the mechanical properties of DMAES films and the adhesion to cotton fiber were investigated. In addition, the desizability and biodegradability of DMAES were measured. It was found that introducing the group of 2-dimethylaminoethyl could toughen the starch film and increase the adhesion to cotton fiber. DMAES has a higher zeta potential and the adhesion to cotton fibers in acidic conditions than in alkaline conditions. In addition, it is easy to remove the DMAES from the yarns and obtain higher desizing efficiency with alkali desizing. Tertiary amination of starch with the 2-dimethylaminoethyl group was a good way for starch to improve adhesion and obtain a higher desizing efficiency.
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DOI
高影响因子
危险品化学品经营许可证（带存储）