RSC Advances
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2013
·Vol. 4
·期 5
·2360-2367
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IF 2.562
Jin-Quan Wang,Wei-Guo Cheng,Jian Sun,Tian-Yuan Shi,Xiang-Ping Zhang,Suo-Jiang Zhang
Several novel 2-hydroxymethyl-functionalized ILs act as the catalysts for synthesis of cyclic carbonates from CO2 and epoxides without the use of any co-catalysts or organic solvent. Moreover, the 2-hydroxymethyl-functionalized ILs were compatible with base, which combined with K2CO3 were used as effective catalytic system for green synthesis of dimethyl carbonate from CO2via ethylene carbonate without catalyst separation. Additionally, the mechanistic details of the fixation of CO2 into cyclic carbonate catalyzed by 2-hydroxymethyl-functionalized ILs were also elucidated by density functional theory. The process reported here represents a simple, ecologically safer, cost-effective and energy-saving route to organic carbonates from CO2.
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Scientific Reports
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2014
·Vol. 4
·期 1
·1-7
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IF 5.078
Parhira Supawadee,Zhu Guo-Yuan,Jiang Ren-Wang,Liu Liang,Bai Li-Ping,Jiang Zhi-Hong
Two stereoisomeric cardenolides, uscharin (1) and a new compound, 2′- epi -uscharin (2), were isolated from the latex of Calotropis gigantea (Asclepiadaceae). Their structures were fully elucidated based on their spectroscopic data, X-ray crystallographic data and chemical evidences. Both epimers (1 and 2) exhibited strong inhibitory effects on HIF-1 activity with different magnitudes. Compound 1 showed much more potent activity than 2 and digoxin, a well-known HIF-1 inhibitor. Discrepancy in potencies between 1 and 2 revealed the contribution of a β-configuration of 2′ hydroxyl moiety for HIF-1 inhibitory activity. This is a first report of the activity of HIF-1 inhibition of thiazoline ring-containing cardenolides.
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PubMed
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SYNTHETIC COMMUNICATIONS
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2015
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IF 0.929
Yan Lin,Zhijie Fu,Tianhua Shen,Fengfeng Che,Qingbao Song
An efficient catalyst-free synthesis of 3′-benzoyl-4′,5′-diphenyl-2H-spiro[acenaphthylene-1,2′-pyrrolidin]-2-one derivatives via one-pot 1,3-dipolar cycloaddition of acenaphthenequinone, arylmethyl amines, and chalcones with high regioselectivity is described. The structure of the cycloadducts were characterized by infrared, high-resolution mass spectrometry (electrospray ionization), 1H NMR, and 13C NMR spectra, and the structure of 4a was confirmed using x-ray single-crystal structure analysis.
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JOURNAL OF NON-CRYSTALLINE SOLIDS
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2015
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IF 1.766
Qiang Zhang,Ye Sheng,Keyan Zheng,Xuming Qin,Pingchuan Ma,Haifeng Zou
In this paper, a series of novel inorganic/organic rare earth (europium, terbium) hybrid materials through 2-phenylmalonic acid linkage were synthesized by the sol–gel process. The micro-structure and the luminescent properties of the complicated hybrids were studied in detail by Fourier transform infrared spectroscopy , wide angle x-ray diffraction, themogravimetric analysis, scanning electron microscope, and fluorescence spectra. The above research results indicate that the hybrids possess high thermal-stability, amorphous structure features and especially favorable luminescent performances such as long luminescent decay lifetime, and high quantum yield.
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RSC Advances
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2015
·Vol. 5
·期 29
·22419-22425
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IF 3.84
Kanjun Sun,Miaomiao Dong,Enke Feng,Hui Peng,Guofu Ma,Guohu Zhao,Ziqiang Lei
A novel gel polymer, polyvinyl alcohol-orthophosphoric acid-2-mercaptopyridine (PVA-H3PO4-PySH), is prepared through introducing redox-mediated 2-mercaptopyridine into a polyvinyl alcohol-orthophosphoric acid host, and a solid state supercapacitor is fabricated using the gel polymer as an electrolyte and a separator and using activated carbons as electrodes. The PVA-H3PO4-PySH gel polymer was shown to have excellent stretching and bending properties. The electrochemical properties of the supercapacitor are investigated by cyclic voltammetry, galvanostatic charge–discharge and electrochemical impedance spectroscopy. Surprisingly, electrode specific capacitance (1128 F g−1) and energy density (39.17 W h kg−1) are increased by 447% by introducing PySH as the redox mediator in the PVA-H3PO4 gel polymer. The supercapacitor with the PVA-H3PO4-PySH gel polymer shows an excellent capacitance retention of 80% for over 1000 cycles. Simultaneously, the ionic conductivity of the gel polymer electrolyte increased by 92% up to 22.57 mS cm−1 compared to that of the PVA-H3PO4 system. These improved performances are owed to the redox reaction between 2-mercaptopyridine (PySH) and 2,2′-bipyridine (PySSPy) redox couples in the PVA-H3PO4-PySH gel electrolyte, indicating the supercapacitor combines the double-layer characteristic of carbon-based supercapacitors and the faradaic reactions characteristic of batteries' energy-storage processes.
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Journal of Physical Chemistry C
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2015
·
IF 4.772
Yejun Zhang,Lun Li,Delu Li,Qiangbin Wang
Alloying nanocrystals with multicomponent has been an effective way to tune the band gap of semiconductor nanocrystals, which promises their wide applications in optoelectronics, photovoltaics, etc. However, colloidal synthesis of homogeneous phase multicomponent nanocrystals in a large scale remains great challenge. Here, we declare the successful preparation of single-crystalline quaternary CuSb(SxSe1–x)2 nanosheets in a facile one-pot reaction with yield >3 g. The molar ratio of S/(S + Se) in CuSb(SxSe1–x)2 could be easily tuned from 1.5% to 13.7% by increasing the reaction temperature which enhances the reactivity of S source in the reaction, and accordingly, the band gap of the obtained CuSb(SxSe1–x)2 varies from 0.9 to 1.1 eV.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2017
·
IF 3.671
Song Li,Junhui Pan,Guowen Zhang,Jianjian Xu,Deming Gong
In this study, the interaction between di-(2-ethylhexyl) phthalate (DEHP) and calf thymus DNA (ctDNA) was investigated by a combination of multispectroscopic methods, chemometrics algorithm, cyclic voltammetry and molecular simulation. The concentration profiles of the components obtained from resolving the UV–vis absorption data by multivariate curve resolution–alternating least-squares (MCR–ALS) provided a basic evidence for the formation of DEHP–ctDNA complex. Furthermore, the groove binding of DEHP to ctDNA was evidenced by the results from iodide quenching effect, single-stranded DNA quenching effect, melting studies, viscosity measurements and cyclic voltammetry. The binding constant of the complex was in the order of magnitudes of 10 4 L mol −1 , and hydrophobic forces were inferred to drive the binding process. Analysis of Fourier transform infrared spectra suggested that DEHP preferentially bound to A–T rich region of ctDNA in the minor groove, and these results further confirmed by molecular docking. The circular dichroism spectra indicated that DEHP induced a decrease in base stacking degree and an increase in right-handed helicity of ctDNA, but did not cause a significant damage in DNA. This study may improve the understanding of interaction between DEHP and ctDNA and help evaluate the toxicological effect of DEHP.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
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2017
·
IF 3.671
Yukun Jiao,Mengliu Zhang,Shumei Wang,Chunyan Yan
The objectives of this study were to evaluate the anti-diabetic and anti-hyperlipidemic effects and relative mechanisms of guava polysaccharides (GPs) in rats with type 2 diabetic mellitus (T2DM). The chemical characterization and monosaccharide compositions of GPs, named as GP-1, GP-2, GP-3, and GP-4, were determined by PMP-HPLC and FT-IR. The results revealed that all GPs had the typical saccharide absorptions, and all were heteropolysaccharides. In addition, GPs efficiently decreased levels of fasting blood glucose, glucosylated serum protein, serum insulin, homeostasis model assessment of insulin resistance, total cholesterol, triglyceride and serum alanine transaminase, improved oral glucose tolerance, and increased insulin sensitivity in rats with T2DM. Histopathological observations suggested that GP-1, GP-3, and GP-4 could alleviate injury in pancreatic islet cells, and Western blot analysis showed that these GPs upregulated gene expression of the insulin receptor, insulin receptor substrate 2, Akt, and glucose transporter type 4. Taken together, these data suggest that GPs may be beneficial in treating T2DM and reducing the risk of hyperlipidemia, vascular disease, and cirrhosis via the PI3K/Akt signaling pathway.
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SENSORS AND ACTUATORS B-CHEMICAL
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2024
·
IF 8
Xuemeng Li,Jinxiu Wei,Kai Zhu,Yuanyuan Liu,Lei Wu,Kuo Yang,Shenfei Zong,Zhuyuan Wang,Yiping Cui
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) caused the global pandemic known as coronavirus disease 2019 (COVID-19). Accurate screening of SARS-CoV-2 is crucial in controlling the spread of the virus. Moreover, the false positive diagnosis will cause significant waste of the medical resources. Hence, we introduce a s uper- r esolution d ual f luorescence c o-localization (SR-DFC) strategy for the detection of SARS-CoV-2, which can greatly reduce false positive rates. In the SR-DFC assay, fluorescent capture probes are first modified onto periodically structured gold array substrates to capture the spike protein of SARS-CoV-2. Then, fluorescent recognition probes are added to identify SARS-CoV-2, forming sandwich-like immune complex structures. SR-DFC is realized by utilizing single-molecule localization microscopy (SMLM). Specific recognition of SARS-CoV-2 will induce high fluorescence colocalization between the capture probes and recognition probes. Owing to the high spatial resolution of SMLM, nonspecific adsorption can be well excluded, which greatly improves the specificity and significantly reduces false positive rates. Using a pixel counting method proposed by our group, quantitative detection of SARS-CoV-2 could be realized. The detection range covered in this study is between 0.1 ng/mL to 1000 ng/mL. By simply changing capture probes and recognition probes, the SR-DFC strategy is feasible for the detection of other targets, indicating a good universality. Such a highly accurate sensing strategy holds promising potential in the screening of infectious diseases.
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ELECTROCHIMICA ACTA
·
2024
·
IF 5.5
Yuhui Wang,Tong Zhang,Yong Huang,Shaonan Gu,Shu Zhang,Zhi Wang,Junhao Liu,Xuzhong Gong
Precise regulation of oxygen reduction reaction (ORR) for 2e-ORR or 4e-ORR is of great importance in designing efficient catalysts for electrochemical reactions. Currently, the exact roles of the functional groups and their possible synergistic functions still remain controversial. In this work, catalysts with different combinations of N and O functional groups were prepared using graphite to regulate ORR selectivity. Meanwhile, the quantum chemical parameters of various functional group combinations in the literature were summarized by using DFT calculation, and a method was provided to explain the relationship between functional group combinations, electronic structure and ORR selectivity by HOMO orbital delocalization index (ODI H ) and Mulliken population (MP). Finally, combining the molecular level calculations, a close correlation between the molecular structures with the tendency of 2e-ORR or 4e-ORR was established. Among them, the combination of C=O, N-Graphitic and Pyridinic-Pyrrolic-Graphitic nitrogen structure promoted 4e-ORR. C-O, O=C-O, N-Pyridinic and N-Pyrrolic promoted 2e-ORR. This study has revealed the essential difference between 2e-ORR and 4e-ORR, and provided a direction for determining the structure of 2e-ORR or 4e-ORR catalysts.
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PHYTOCHEMISTRY
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2024
·
IF 3.2
Hao-Dong Yang,Yuan-Gui Yang,Zhi-Shu Tang,Kang Ma,Hong-Bo Xu
Acanthopanacis cortex (the dried root bark of Acanthopanax gracilistylus W. W. Smith) has been used for the treatment of rheumatic diseases in China for over 2000 years. Four previously undescribed lignans ( 1 – 4 ) and 12 known lignans ( 5 – 16 ) were isolated from Acanthopanacis cortex. In this study, the inhibitory activities of compounds 1 – 16 against neutrophil elastase (NE), cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) are reported. The results show that compounds 1 – 16 exhibit weak inhibitory activities against NE and COX-1. However, compounds 2 , 6 – 8 and 13 – 16 demonstrate better COX-2 inhibitory effects with IC 50 values from 0.75 to 8.17 μ Μ. These findings provide useful information for the search for natural selective COX-2 inhibitors.
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Surfaces and Interfaces
·
2025
·
IF 6.3
Jinyue Yang,Jianxin Wang,Yongwen Lin,Xin Huang,Guangming Yin,Haixia Yu,Wendi Wang,Xinyou Zhang,Hong Pan
Transition metal sulfides are considered potential electrode materials for supercapacitors because of their low electronegativity, high electrochemical activity, and rich oxidation–reduction properties , but they also have the disadvantages of poor cycle stability and low magnification performance. In-situ growth sulfides on the current collector can strengthen the structural stability of the electrode to a certain extent, but this method only obtains a weak binding of the sulfide and current collector. With the progress of cycling, repeated structural evolution will inevitably lead to metal dissolution and sulfide shedding. In this study, nickel-poor reactants were cleverly adopted to synthesize one in-situ sulfide on nickel foam (NF) by activating the nickel element in NF to participate in the formation of sulfide, so as to obtain the in-situ electrode material with flower shape and gradient Ni content, named as Ni (2-x) CoS 4 /Ni 2 CoS 4 /Ni electrode. By further compounding polyaniline (PANI) on the surface of Ni (2-x) CoS 4 /Ni 2 CoS 4 /Ni electrode, the in-situ gradient Ni (2-x) CoS 4 /Ni 2 CoS 4 /Ni-PANI composite electrode (ISG-NCS-PANI) was obtained. This in-situ bimetallic sulfide has not only high stability, but also high reactivity. The flower shape with a large specific surface area is also beneficial to enhance the rate performance. As a result, the specific capacitance of the composite electrode is up to 2909.4 F g −1 at 1 A g −1 . After 5000 cycles, the capacity remains 83.8 %. The asymmetric supercapacitor (ASC) composed of activated carbon (AC) negative electrode has a specific capacitance of 211.11 F g −1 at 1 A g −1 . The power density of 749.99 W kg −1 shows the maximum energy density of 65.97 Wh kg −1 . The above results prove that ISG-NCS-PANI electrode holds significant potential for application prospect in the domain of energy storage and conversion.
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