Nature Communications
·
2020
·Vol. 11
·期 1
·1-15
·
IF 12.121
Zheng Di-Wei,Hong Sheng,Zhang Qiu-Ling,Dong Xue,Pan Pei,Song Wen-Fang,Song Wen,Cheng Si-Xue,Zhang Xian-Zheng
Global alterations in the metabolic network provide substances and energy to support tumor progression. To fuel these metabolic processes, extracellular matrix (ECM) plays a dominant role in supporting the mass transport and providing essential nutrients. Here, we report a fibrinogen and thrombin based coagulation system to construct an artificial ECM (aECM) for selectively cutting-off the tumor metabolic flux. Once a micro-wound is induced, a cascaded gelation of aECM can be triggered to besiege the tumor. Studies on cell behaviors and metabolomics reveal that aECM cuts off the mass transport and leads to a tumor specific starvation to inhibit tumor growth. In orthotopic and spontaneous murine tumor models, this physical barrier also hinders cancer cells from distant metastasis. The in vivo gelation provides an efficient approach to selectively alter the tumor mass transport. This strategy results in a 77% suppression of tumor growth. Most importantly, the gelation of aECM can be induced by clinical operations such as ultrasonic treatment, surgery or radiotherapy, implying this strategy is potential to be translated into a clinical combination regimen.
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BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
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2021
·Vol. 107
·期 2
·255-262
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IF 2.151
Liu Jingliang,An Fengxia,Li Mei,Yang Lu,Wan Jinzhong,Zhang Shengtian
Sulfate radical based-advanced oxidation process has received increasing interest in the remediation of wastewater and contaminated soil. In this study, degradation of 2, 4-dichlorophenol (2, 4-DCP) was investigated over peroxymonosulfate (PMS) activation by MnO 2 , which was prepared by liquid-phase oxidation method. The prepared MnO 2 was characterized by transition electron microscopy, X-ray diffraction, N 2 adsorption–desorption, and X-ray photoelectron spectroscopy. Characterization results showed that α-MnO 2 exhibited the highest surface area and Mn (III) content. The PMS activation by MnO 2 in 2, 4-DCP degradation followed the order of α-MnO 2 > γ-MnO 2 > β-MnO 2 , which is dependent on the properties of MnO 2 including crystal structure, surface area and Mn (III) content. Influences of initial concentration of 2, 4-DCP, PMS and MnO 2 dosage, pH and co-existing inorganic ions on the degradation were examined. Electron paramagnetic resonance (EPR) and quenching experiments with ethanol and tert-butanol suggested that sulfate radicals were the dominant radicals in the process. Findings in this study indicated that α-MnO 2 was an attractive catalyst for activation of PMS to degrade 2, 4-DCP in aqueous solution.
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JOURNAL OF SOLID STATE ELECTROCHEMISTRY
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2021
·Vol. 25
·期 3
·1111-1120
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IF 2.647
Wang Zhiwei,Ru Juanjian,Hua Yixin,Bu Jiaojiao,Geng Xiao,Zhang Wenwen
Tin (Sn) powders with pyramid chain and dendrite structures are successfully prepared by electrodeposition in choline chloride-ethylene glycol deep eutectic solvent (ChCl-EG DES) at 343 K. Cyclic voltammetry demonstrates that increasing SnCl 2 concentration from 30 to 70 mM is favorable for the reduction of Sn(II) ions to metallic Sn on Ni electrode. The roles of current density (10–30 mA·cm −2 ) and SnCl 2 concentration (30–70 mM) on the current efficiency and energy consumption are discussed during the electrodeposition of Sn powders. Experimental results show that the current efficiency and energy consumption are 88.7% and 347.1 kW·h·t −1 , respectively at 20 mA·cm −2 and 50 mM SnCl 2 . Besides, the micromorphology and crystal structure of Sn powders are analyzed by FESEM and XRD. Morphology analysis manifests that pyramid chains and dendrites in length of 30–220 μm are the dominate morphologies and the formation mechanism of the pyramid chain is also discussed. Moreover, XRD analysis and crystal texture reveal that metallic Sn is obtained with a body-centered tetragonal crystal structure. The (101) plane is the preferred at higher current density, while the (200) plane gets the strongly preferred orientation as SnCl 2 concentration increases. Graphical abstract
Sn powders electrodeposited from SnCl 2 -ChCl-EG solution and growth mechanism of the pyramid chain structure.
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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
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2021
·Vol. 32
·期 5
·5781-5789
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IF 2.478
Han Dandan,Shen Ye,Zhao Yuan,Pan Yifan,Wei Jinhe,Wei Yen
In this work, hierarchically porous MnO/carbon (MnO/C) microsphere materials were fabricated by a facile two-step approach. The MnO precursors and the polymerization of dopamine were synthesized simultaneously by chemical solution method at room temperature. The dopamine plays a key role in the formation of MnO/C, which guides the growth of porous spherical structures and acts as a carbon source. The enhancement of electrochemical properties and electrical conductivity strongly depend on the porous structure of the composite electrodes. Benefiting from the unique structures, the optimized MnO/C electrode delivered a high specific capacitance of 378 F·g −1 at 0.1 A·g −1 and retained over 96.66% of its initial capacitance after 1000 cycles at 1 A·g −1 , suggesting that MnO/C hybrid material has promising potential for practical supercapacitors.
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WATER AIR AND SOIL POLLUTION
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2021
·Vol. 232
·期 2
·1-15
·
IF 2.52
Zhang Hongling,Shi Mingxing,Xia Mingzhu,FengyunWang,Zhao Feng
Previous researches investigated the adsorption properties and mechanism of clay minerals on antibiotic pharmaceuticals and personal care products (PPCPs) via batch adsorption experiments and X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) characterization, but many PPCPs exhibit different ionization states under different pH conditions; the research on the microscopic mechanism of different ionized PPCPs species adsorbed by clay minerals is very scarce. In this work, as a typical PPCPs contaminant, the common tetracycline (TC) was chosen as the study target; the adsorption micro mechanism of montmorillonite (MMT) on different TC species in aqueous solution was explored in details. Especially outstanding, for the first time, with the help of Multiwfn wavefunction program, quantitative analysis of molecular surface analysis and basin analysis were applied to quantitatively investigate the electrostatic interaction between MMT and different TC species, the possible positions of lone pair electrons. Independent gradient model (IGM) analysis and Hirshfeld surface analysis including local surface analysis were integrated to visualize the binding sites, interaction types, and relative strength between MMT and TC +/− or TC +/2− species, which can insight into the interaction essence from the microscopic perspective at the atomic level.
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JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
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2021
·Vol. 147
·期 3
·2239-2251
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IF 4.626
Zhao Qian,Wang Bowen,Qin Chenyuan,Li Qiuxuan,Liu Chuntai,Shen Changyu,Wang Yaming
In this work, biodegradable poly(lactic acid) (PLA)/Ti 3 C 2 T x MXene nanocomposites were prepared through melt compounding. The roles of MXene in nonisothermal melt and cold crystallization of PLA were explored. The morphology, structure and crystallization behavior were studied using polarized optical microscopy, wide-angle X-ray diffraction and differential scanning calorimetry. For nonisothermal melt crystallization, the presence of MXene increases the crystallinity and shortens the half-crystallization time but does not change the crystallization peak temperature of PLA. For nonisothermal crystallization from the glassy state, the incorporation of MXene decreases the cold crystallization peak temperature and reduces the crystallinity marginally but does not affect the half-crystallization time of PLA. The crystallization kinetics analysis based on the Avrami equation shows that, for both the melt and cold crystallization, the crystallization mechanism is unchanged irrespective of the addition of MXene. The investigation would be useful for understanding the correlation between processing and properties of PLA/MXene nanocomposites.
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CHINESE JOURNAL OF POLYMER SCIENCE
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2021
·Vol. 39
·期 6
·736-744
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IF 3.603
Wang Hao,Liu Han-Chao,Zhang Yao,Xu Hu,Jin Bi-Qiang,Cao Zhen-Xing,Wu Hai-Tao,Huang Guang-Su,Wu Jin-Rong
It remains a challenge to use a simple approach to fabricate a multi-shape memory material with high mechanical performances. Here, we report a triple crosslinking design to construct a multi-shape memory epoxy vitrimer (MSMEV), which exhibits high mechanical properties, multi-shape memory property and malleability. The triple crosslinking network is formed by reacting diglycidyl ether of bisphenol F (DGEBF) with 4-aminophenyl disulfide, γ -aminopropyltriethoxysilane (APTS) and poly(propylene glycol) bis(2-aminopropyl ether) (D2000). The triple crosslinking manifests triple functions: the disulfide bonds and the silyl ether linkages enable malleability of the epoxy network; the silyl ether linkages impart the network with high heterogeneity and broaden the glass transition region, leading to multi-shape memory property; a small amount of D2000 increases the modulus difference between the glassy and rubbery states, thereby improving the shape fixity ratio. Meanwhile, the high crosslinking density and rigid structure provide the MSMEV with high tensile strength and Young’s modulus. Moreover, integrating carbon fibers and MSMEV results in shape memory composites. The superior mechanical properties of the composites and the recyclability of carbon fiber derived from the dissolvability of MSMEV make the composites hold great promise as structural materials in varied applications.
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Food Analytical Methods
·
2020
·Vol. 14
·期 3
·616-630
·
IF 2.667
Qi Dandan,Ma Chengying,Wang Wenwen,Zhang Licui,Li Jianke
Royal jelly produced by nurse bees from tea tree (tea royal jelly) is a special bee product in China and it is popular with consumers owing to its multiple healthcare functions. However, the volatile compound profile of tea royal jelly has not been investigated. To obtain a comprehensive understanding of volatile compound profile of tea royal jelly, a method based on headspace solid-phase microextraction coupled with gas chromatography-mass spectrometry (HS-SPME/GC-MS) and chemometric analysis was applied. Moreover, two royal jelly samples produced from pagoda tree were also investigated to reveal the difference in volatile compounds between royal jelly produced from tea tree and other plants. A total of 66 volatile compounds were identified in tea royal jelly, including 16 alkanes, 14 aldehydes, 9 alcohols, 9 ketones, 8 esters and lactones, 5 phenols, 2 organic acids, and 3 other compounds, and most of them were discovered in royal jelly for the first time. Notably, α -ionone, an important aroma compound in tea, was first identified in tea royal jelly. Moreover, the result of chemometric analysis indicates a significant difference on volatile compound profile between royal jelly produced from tea and pagoda trees. To sum up, 35 differential compounds were identified and they could well distinguish royal jelly samples. Our data offers the first characterization of volatile compound profile of tea royal jelly and significantly expands the knowledge of volatile compounds in royal jelly. It is potentially useful as a new approach to distinguish royal jelly produced from different botanical origins.
Graphical abstract
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JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
·
2020
·Vol. 326
·期 3
·1843-1852
·
IF 1.137
Wang Zili,Liu Zhirong,Ye Tianzhen,Wang Yun,Zhou Limin
The tannic acid-chitosan hydrothermal carbon (TCHC) by hydrothermal carbonization is first used in uranium(VI) adsorption. The characterization of HCTC was investigated by scanning electron microscopy, X-ray diffraction, infrared spectroscopy (FTIR). The effects of pH, adsorbent dosage, initial U(VI) concentration, temperature and contact time on the adsorption of uranium(VI) were expressed in batch experiments. A maximum adsorption capacity 96.99 mg/g has been achieved at pH = 5.5, T = 25 °C and initial concentration of U(VI) solution 80 mg/L. The adsorption data fit well with the Langmuir model and pseudo second order kinetics model, indicating that uranium(VI) was monolayer covered on the surface of the material, and the adsorption process was mainly chemisorption. Thermodynamic data indicates that the immobilization of uranium(VI) to the material surface was spontaneous and endothermic. TCHC in low-cost is a promising adsorbent for uranium(VI) adsorption.
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ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2020
·Vol. 28
·期 10
·12909-12917
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IF 3.056
Ren Jingyu,Li Jie,Lv Lei,Wang Jian
Ionic liquids (ILs) are a kind of promising extractants for removing undesirable organics from industrial wastewater and crude oil, etc. Herein, IL regeneration by ozonation was proposed for its recycling. 1-Butyl-3-methylimidazolium tetrafluoroborate ([Bmim]BF 4 ) and phenol were used as the representative IL and organic matter, respectively. The regeneration performance, stability of [Bmim]BF 4 , and roles of hydrogen bonds between O 3 and [Bmim]BF 4 in the phenol removal were studied. The experimental results showed that 90.2% of phenol was degraded in [Bmim]BF 4 after ozonation treatment for 30 min with the O 3 concentration of 1.2 mg/L. The nonvolatility of [Bmim]BF 4 -made phenol was adequately degraded, while the concentration of phenol increased during ozone treatment in the conventional extractants (ethanol, ethyl acetate, and dichloromethane) due to their high volatility. The reuse experiments, spectra of Fourier transform infrared spectroscopy and 1 H nuclear magnetic resonance spectroscopy indicated that [Bmim]BF 4 was steady under the ozonation process. Density functional theory simulation confirmed that hydrogen bonds between [Bmim] + and O 3 could be formed, and calculational results of Hirshfeld charges indicated that the nucleophilicity of O 3 was enhanced by the hydrogen bonds. The enhanced nucleophilicity resulted in the increase of phenol degradation efficiency by ozonation, and the synergistic effect between O 3 and ILs was proportional to the hydrogen bond donor ability of ILs.
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MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 3
·1-9
·
IF 5.833
Xian Zhiquan,Zhang Li,Yu Ying,Lin Bixia,Wang Yumin,Guo Manli,Cao Yujuan
A nanozyme based on CoFe 2 O 4 modified with MoS 2 was constructed for colorimetric determination of cysteine (Cys) and glutathione (GSH). Firstly, ferrite CoFe 2 O 4 is synthesized, and it is then modified by MoS 2 to form a flower-like polymer (MoS 2 @CoFe 2 O 4 ). In the presence of H 2 O 2 , a redox interaction takes place, and the resulting hydroxyl promoted a colorimetric conversion from colorless to blue in the presence of 3,3′,5,5′-tetramethylbenzidine (TMB). However, once Cys or GSH is added, they are capable to compete with the interaction of the hydroxyl with TMB, resulting in an inhibition of the colorimetric conversion. The colorimetric distinction is sensitive to the amount of target. The results obtained proved that the catalytic efficiency of MoS 2 @CoFe 2 O 4 is 4.4-fold and 1.8-fold to that of MoS 2 and CoFe 2 O 4 . Meanwhile, the K m values to TMB and H 2 O 2 are 0.067 and 0.048 mM, respectively, which are 6.5-fold and 77-fold, respectively smaller than those of natural peroxidase such as HPR. This indicates that the MoS 2 @CoFe 2 O 4 possesses a favorable interaction affinity. Additionally, the colorimetric distinction caused by the competition between TMB and cysteine or glutathione is obvious. The signal responses to cysteine and glutathione are linear in the range 0.5~15 μM and 0.5~35 μM, and the LODs are 0.10 and 0.21 μM, respectively. In practical assay of Cys in serum, the RSD of the sample tests is 4.6%, and the recoveries for the spiked assays are 95.3% and 96.0% with the RSD of 2.1% and 4.2%, respectively. Graphical abstract
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POLYMER BULLETIN
·
2021
·Vol. 79
·期 2
·1201-1216
·
IF 2.87
Yu Changjiang,Li Han,Ma Haoyue,Zhang Limei,Li Yu,Lin Qiang
A magnetic composite microsphere, calcium alginate (CA)/carboxymethyl cellulose (CMC)@MnFe 2 O 4, was prepared using CA and CMC encapsulated MnFe 2 O 4 through blending and cross-linking for the removal of Cu(II) from aqueous solution. The CA/CMC@MnFe 2 O 4 was characterized in detail by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscopy, and X-ray phosphorescence spectroscopy. In addition, various adsorption conditions including the initial pH of Cu(II) solution, equilibrium contact time, and initial Cu(II) concentration were tested. The adsorption data fit better to the Langmuir isotherm and follow the pseudo-second-order model, suggesting that it is a monolayer adsorption process with chemisorption as the rate-limiting step. The maximum adsorption capacity of the CA/CMC@MnFe 2 O 4 was 77.22 mg g −1 at 25 ℃ and pH 5. Cu(II) removal mechanisms of CA/CMC@MnFe 2 O 4 follow ion exchange as well as the formation of complexes as evidenced based on the microstructure analysis and adsorption data fitting.
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