BIOSENSORS & BIOELECTRONICS
·
2019
·
IF 9.518
Jinglong Fang,Guanhui Zhao,Xue Dong,Xuan Li,Juncong Miao,Qin Wei,Wei Cao
An electrochemiluminescence (ECL) analytical platform was proposed for ultrasensitive detection of amyloid-β proteins (Aβ) based on the ECL resonance energy transfer (ECL-RET). In this work, gold nanoparticles-functionalized graphitic carbon nitride nanosheets (g-C 3 N 4 @Au NPs) and palladium nanoparticles-coated Metal organic framework (Pd NPs@NH 2 -MIL-53) were synthesized, which were as ECL donor and ECL acceptor respectively. A strong cathode ECL emission was obtained from the g-C 3 N 4 @Au NPs when used K 2 S 2 O 8 as its co-reactant. Here, Au NPs not only was used as an accelerator to enhance and stabilize the ECL signal, but also a connector for attaching Aβ antibody. In addition, NH 2 -MIL-53(Al) was selected as a label material for supporting Pd NPs to synergistically increase the intensity and range of UV-visible absorption. The ECL signal of g-C 3 N 4 @Au NPs was intensely decreased when the ECL acceptor probe Pd NPs@NH 2 -MIL-53 was incubated onto the modified GCE by way of the specific recognition. Under the optimal condition, a wide detection range from 10 fg/mL to 50 ng/mL and a low detection limit of 3.4 fg/mL (S/N = 3) were obtained. In consideration of favorable specificity, stability and reproducibility, the proposed method was successfully applied for Aβ detection in actual human serum samples and could be a potential analytical tool for sensitive molecular trace detection in clinical analysis.
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高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 13.273
Zhenfei Yang,Xinnian Xia,Luhua Shao,Longlu wang,Yutang Liu
Herein, Ag 3 PO 4 /mixed-valence MIL-88A(Fe) [AMM] Z-scheme heterojunctions with an in-situ-generated photo–Fenton process were successfully constructed. The optimized AMM-20 heterojunctions show the maximum rate of photocatalytic TC degradation, which is 2.5 and 6.6 times of pristine Ag 3 PO 4 and MIL-88A(Fe). The electronic and band structures of Ag 3 PO 4 , MIL-88A(Fe), m-MIL-88A(Fe) and AMM heterojunctions were deeply investigated by both experimental and theoretical simulation. The Z-scheme transfer pathway greatly accelerates the transfer rate of charge carriers and effectively inhibits the photocorrosion, leading to the improvement of photocatalytic activity and photostability. Moreover, the adjustment of the Fe II /Fe III ratio of mixed-valence MIL-88A(Fe) further enhances the photocatalytic activity of the hybrid photocatalysts, benefiting from the promotion of the efficiency of the in-situ-generated photo-Fenton process. The Z-scheme transfer route coupling with an in-situ-generated photo–Fenton process was verified by the free radical trapping experiment, in-situ XPS measurement, in-situ ESR measurement, and coumarin fluorescence analysis. The degradation pathways of TC were determined through LC-MS analysis and theoretical calculation. Furthermore, the toxicity of intermediates was evaluated by QSAR prediction.
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高影响因子
DALTON TRANSACTIONS
·
2020
·Vol. 49
·期 20
·6651-6660
·
IF 4.174
Ji-Min Yang,Wei Zhang,Run-Zhi Zhang,Meng-Xuan Tong
Toxic dyes pose a dramatic threat to human health and the environment when they are directly released into the water environment. Therefore, new porous materials with excellent adsorption performances are urgently needed to remove toxic dyes from wastewater. Herein, we report a sulfo-modified metal–organic framework (MIL-101-SO3H), which exhibits superior adsorption performance toward toxic dyes. The free –SO3H groups were successfully introduced into the MIL-101(Cr) skeleton to modulate the adsorption driving forces (i.e., hydrogen bonding, electrostatic attractions, and π–π stacking interactions together with adsorption spaces and steric hindrance) between the toxic dyes and MIL-101-SO3H adsorbent by varying the monosodium 2-sulfoterephthalic acid-to-terephthalic acid molar ratio in the reaction mixture. The experimental adsorption uptake by MIL-101-SO3H-1 was found to be 688.9 (methyl orange), 2592.7 (Congo red), and 213.2 (acid chrome blue K, AC) mg g−1, which was respectively 69.6, 89.6, and 51.5% higher than those of undecorated MIL-101. This adsorption behavior was attributed to the dye molecular structure, pore volumes, surface charge status, and functional groups of the adsorbents as well as the adsorption capacity of the dyes. The results revealed that the uncoordinated –SO3H groups increased the electrostatic attraction and hydrogen bonding between the MIL-101-SO3H adsorbent and linear anionic dyes. This increased the adsorption capacity toward the linear anionic dyes, overriding the effect of the pore volumes. On the other hand, the steric hindrance between the nonlinear anionic dye AC and MIL-101-SO3H adsorbent decreased the AC adsorption uptake of the latter, overriding the effects of hydrogen bonding and electrostatic attraction. In addition, the adsorption performance toward the cationic dye methylene blue increased, owing to the hydrogen bonding interactions, thereby overriding the effect of electrostatic repulsion and adsorption spaces. Thus, it is concluded that the adsorption behavior of the modified MIL-101-SO3H adsorbent is governed by the synergetic interplay between the electrostatic attraction, hydrogen bonding, and π–π stacking interactions as well as the steric hindrance and pore volumes of the adsorbent.
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CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Luogen Lai,Wanqing Zou,Yan Zhang,Yuanbiao Tu,Simeng Li,Tongxuan Xin,Tianyue Zhou,Shan Xu,Pengwu Zheng,Qingshan Pan,Wufu Zhu
Bacterial infections and antibiotic resistance have become a global healthcare crisis. There is an urgent need to develop visualized therapeutic platforms that allow accurate imaging of the bacterial infections, successful eradication of bacteria and real-time monitoring of treatment progress. In this work, we report a novel NIR imaging and synergistic antibacterial nano-system ( [email protected] ) for resistance bacterial infection therapy. The multifunctional nano-system is fabricated by a MIL-101 core, which is covalently connected with Vancomycin and modified with targeted antimicrobial peptides LL-37 on the surface. The ability of monitoring the progress of infection treatment and effective promoting wound healing of bacterial infection are proved by in vivo MRSA -infected mice models. Under the environment of endogenous H 2 O 2 overexpression and slightly acid bacterial infection, the excellent Fenton-like reaction activity of [email protected] could effectively catalyze the decomposition of H 2 O 2 to produce hydroxyl radicals (•OH), which trigger highly efficient chemo-dynamic therapy (CDT) and tissue protection effect. By combining CDT with antibacterial peptides and antibiotics therapy, special targeting and synergistic killing of MRSA are successfully achieved in in vitro and in vivo antibacterial assays with excellent biocompatibility. Due to this, this study proposes a novel, high-efficient, multifunctional imaging and therapy system, which will open a new avenue for the design of synergistic antibacterial and diagnostic platforms in the future.
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高影响因子
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2025
·
IF 8.5
Jiang Chang,Ying Qin,Weimin Guo,Jingyuan Zhang,Kuo Zhang,Jianhua Zheng,Lijian Sun,Qiu Fu
The facile and eco-friendly fabrication of a fabric with remarkable flame retardancy, anti-ultraviolet (UV), and superhydrophobic properties is of significant interest for multitask requirements. In this regard, herein, a nonfluorine, facile, and green method is reported for in situ synthesis of metal-organic frame (NH 2 -MIL-53(Al)) on hemp fabric (HF) for the preparation of multifunctional textiles. A homogeneous and compact coating of NH 2 -MIL-53(Al) crystals was deposited on HF, followed by modification with triethoxyoctylsilane (TEOS) to manufacture superhydrophobic NH 2 -MIL-53(Al)@hemp fabric (SM(Al)HF-9), significantly enhancing its water stability. The SM(Al)HF-9 exhibited superior superhydrophobicity properties, with a water contact angle (WCA) up to 156°. Furthermore, the surface of SM(Al)HF-9 cannot be adhered by dye solution and powder, indicating its good self-cleaning and anti-fouling abilities. The SM(Al)HF-9, characterized by a porous structure, effectively separates tetrachloromethane and n-hexane from water mixtures with a separation efficiency exceeding 97 %. The SM(Al)HF-9 has excellent UV-blocking properties, and the UV protection factor is as high as 105.44. Encouragingly, the SM(Al)HF-9 exhibited outstanding flame retardancy, as demonstrated by its self-extinguishing capability and a substantially improved limiting oxygen index (LOI) of 32.4 %. In comparison to raw HF, the peak heat release rate (PHRR) and total heat rate (THR) of the modified HF are reduced by 76.15 % and 54.32 %, respectively. Meanwhile, the NH 2 -MIL-53(Al) has a significant advantage over other MOFs (e.g., ZIF-67, Ce-MOF, Ag-MOF, Fe-MOF and MIL-53(Al)) in improving the flame retardancy of HF. The highly efficient flame-retardant, anti-UV, and superhydrophobic fabric is promising in home and public decoration, and fire protection fields.
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DOI
PubMed
高影响因子
MICROCHIMICA ACTA
·
2026
·Vol. 193
·期 11
·722
·
IF 5.4
Yin Fengqin,He Xudong,Liu Xueting,Guo Dong,Wang Jiahui,Cui Xinxin,Fang Zongping,Ye Tai,Cao Hui,Hao Liling,Xu Fei
An enhanced ratiometric fluorescence sensor Ru@HFeO@NH 2 -MIL-101 (Fe) for the determination of arsenate was constructed by using HFeO-modified NH 2 -MIL-101 (Fe) as the response signal and Ru(bpy) 3 2+ as the reference signal, which can be used for sensitive and visual detection of As(V). Because the HFeO nanoparticles were cleverly in-situ generated within the NH 2 -MIL-101(Fe) framework, the adsorption capacity of As(V) was enhanced 32% and further increased fluorescence ratio. The sensor exhibited a good linear relationship within As(V) concentration range 0.05-1 and 3–30 µM, with a detection limit (LOD) of 0.039 µM. The sensor also exhibited good selectivity and practical application performance, and can be utilized by a smartphone for visual detection of As(V). This provides an effective method for the sensitive detection of As(V) in complex environmental conditions. Graphical
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Si Duan,Yuanhua Lin,Guihong Lan,Yudi Jing,Mohd Talha
Antibiotic pollution and resistance spread pose urgent environmental risks, compounded by coexisting multiple antibiotics. To address this, this study aims to enhance the adsorption of typical antibiotics (tetracycline, TC; ciprofloxacin, CIP) through structural and functional modulation of metal-organic frameworks (MOFs). Focusing on MIL-101(Fe), a series of NH 2 -MIL-101(Fe) materials with tunable amination degrees were prepared via a mixed-ligand strategy, which involves adjusting the molar ratio of terephthalic acid (H 2 BDC) to 2-amino terephthalic acid (NH 2 -H 2 BDC). This strategy breaks through the limitations of traditional single-ligand systems. Results revealed that the NH 2 -MIL-101(Fe)-3 (H 2 BDC: NH 2 -H 2 BDC = 1:3) exhibited remarkable adsorption performance in both single and binary systems. The maximum adsorption capacities for TC and CIP reached 827.75 mg/g and 806.26 mg/g, respectively, representing significant increases of 46.34 % and 52.44 % compared to pristine MIL-101(Fe). Although the adsorption capacities decreased in the competitive binary system, they still achieved 641.17 mg/g and 588.43 mg/g for TC and CIP, respectively, outperforming most reported adsorbents. Additionally, NH 2 -MIL-101(Fe)-3 demonstrated robust tolerance to interference from inorganic ions and natural organic matter, along with excellent cyclic regeneration performance. FTIR, XPS, and density functional theory (DFT) calculations clarified mechanisms: -NH 2 groups enhanced the material's polarity and hydrophilicity, facilitating hydrogen bonding; Fe 3 + -antibiotic chelation dominated, supplemented by π-π stacking and pore-filling effects. This multi-mechanism synergy, quantified by DFT-derived binding energies (coordination > hydrogen bonding > π-π interactions). Overall, this study underscores the potential of mixed-ligand functionalized MOFs in addressing complex pollution systems, providing a theoretical foundation for high-performance adsorbent design and antibiotic pollution control.
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Jialin Pang,Yao Zhu,Meiqian Li,Jicheng Xu,Ziyu Yuan,Yilmaz Yurekli,Yuting Dai,Tao Zhang,Dongya Yang,Fengxian Qiu
Hg 2+ contamination in aquatic environments represents a significant threat to human health and ecological systems due to its pronounced toxicity and enduring nature. It is imperative to develop a high-performance, recyclable adsorbent for Hg 2+ removal to enable effective treatment of wastewater. Herein, MIL-101@MXene was synthesized through in-situ hydrothermal growth of MIL-101 on MXene substrates, and was subsequently incorporated into a double-network hydrogel matrix comprising polyvinyl alcohol (PVA) and chitosan (CS), resulting in the formation of the MIL-101@MXene/hydrogel adsorbent. A comprehensive characterization of MIL-101@MXene/hydrogel was conducted utilizing a series of analytical techniques, including X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), Brunauer-Emmett-Teller (BET) analysis, and X-ray photoelectron spectroscopy (XPS). The porous hydrogel network of MIL-101@MXene/hydrogel, along with the micro-mesoporous structure of MIL-101@MXene, creates a hierarchical pore architecture. In this configuration, the macropores of the hydrogel facilitate efficient diffusion of Hg 2+ into the material's interior while promoting physical adsorption. Meanwhile, the micro-mesopores not only provide a substantial specific surface area but also reveal numerous active adsorption sites, thereby enhancing the overall adsorption capacity. Batch adsorption experiments demonstrated that MIL-101@MXene/hydrogel exhibited optimal performance for the removal of Hg 2+ at a pH of 5, achieving a maximum adsorption capacity. In addition, MIL-101@MXene/hydrogel demonstrated competitive selectivity and reusability, with only about a 25 % reduction in Hg 2+ adsorption capacity in the presence of various competing ions, and retaining over 55 % of its initial capacity after six successive adsorption-desorption cycles. The adsorption mechanism was further elucidated through FT-IR and XPS analyses conducted both before and after the adsorption process. The results highlighted the coordination of Hg 2+ with unsaturated Fe 3+ sites and carboxyl oxygen atoms, as well as surface complexation between Hg 2+ and the functional groups on MXene. Physisorption also contributed to the overall adsorption process. Additionally, there were interactions characterized by hydrogen bonding and coordination between the hydrogel matrix and Hg 2+ . This work indicates that MIL-101@MXene/hydrogel is an effective adsorbent with practical potential for Hg 2+ -contaminated wastewater remediation.
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高影响因子
Desalination and Water Treatment
·
2024
·
IF 1
Abdelazeem S. Eltaweil,Eman M. Abd El-Monaem,Ahmed M. Omer,Randa E. Khalifa,Mona M. Abd El-Latif,Gehan M. El-Subruiti
MIL-101(Fe) iron-benzene dicarboxylate based metal-organic framework (MOF) was synthesized via a solvothermal method for adsorptive removal of cationic methylene blue (MB) dye from aqueous solution. The prepared MIL-101(Fe) was characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, transmission electron microscopy, thermal gravimetric analyzer, X-ray photoelectron spectroscopy, and Brunauer–Emmett–Teller analysis tools. Various parameters affecting the removal efficiency were deliberated such as pH medium, contact time, solution temperature, MOF dosage, and initial MB dye concentrations. Results showed that MIL-101(Fe) has a maximum adsorption capacity of 58.82 mg/g at pH 9. Moreover, data obtained from isotherm studies were more fitted to the Langmuir isotherm model (R 2 = 0.997), while the adsorption kinetics followed the pseudo-second-order model. The thermodynamic studies proved that the adsorption process of MB dye onto MIL-101(Fe) was spontaneous and endothermic. Besides, MIL-101(Fe) showed higher adsorption ability towards cationic MB dye compared to the anionic methyl orange dye. Finally, the MIL-101(Fe) adsorbent showed excellent reusability for removing MB dye with efficiency exceeded 70% after ten consecutive cycles. Therefore, the as-prepared MIL- 101(Fe) could be applied as a reusable adsorbent for removing cationic dyes from their aqueous solutions.
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高影响因子
ANALYTICA CHIMICA ACTA
·
2026
·
IF 6.1
Guobin Huang,Zhonghua Pan,Qilong Wang,Qingqing Liang,Jiayi Wu,Yanmei Zhou,Tianju Chen,Wangchuan Xiao
Background Phthalate acid esters (PAEs) are endocrine-disrupting contaminants that require reliable trace-level monitoring in environmental waters. Magnetic dispersive solid-phase extraction (MDSPE) offers a green sample-preparation approach, but its performance is often constrained by the limited adsorption capacity, poor structural integrity, limited reusability, and high material cost of existing sorbents. Developing a stable, magnetically responsive, and high-affinity nanocomposite to overcome these limitations remains a critical challenge. Results A novel ternary magnetic MWCNTs@Fe 3 O 4 @MIL-101(Fe) nanocomposite was successfully synthesized via a facile hydrothermal strategy, where multi-walled carbon nanotubes (MWCNTs) serve as a conductive scaffold intertwining Fe 3 O 4 nanoparticles and MIL-101(Fe) crystals. This unique architecture endows the sorbent with high saturation magnetization (58.9 emu/g) for rapid separation, a large specific surface area (1127.28 m 2 /g), and abundant π-electron-rich sites for enhanced adsorption. Under optimized MDSPE conditions coupled with gas chromatography-flame ionization detection (GC-FID), the method achieved wide linear ranges (0.05-2500 μg/L), ultra-low limits of detection (0.005-0.05 μg/L), and satisfactory absolute recoveries (89.5%-110.6%) in real environmental water samples. The sorbent exhibited good reusability (≥90% after five cycles) and excellent precision (RSDs <9.0%). Greenness assessment using the AGREE metric yielded a score of 0.65, reflecting a moderate-to-high level of environmental sustainability. Significance and novelty This work presents a novel “MWCNT-bridged” strategy that successfully integrates magnetic responsiveness, high porosity, and π-π interaction sites into a single, stable sorbent, resolving the common trade-off between functionality and recoverability in magnetic MOF composites. The rationally designed nanocomposite provides a robust, highly sensitive, and environmentally sustainable platform for monitoring trace PAEs in complex aqueous matrices, advancing the development of functional materials for green analytical chemistry.
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PubMed
高影响因子
Food Frontiers
·
2026
·Vol. 7
·期 4
·e70303
·
IF 6.3
Yadi Qin,Jie Qian,Jian Sun,Qinqin Li,Jun Yao,Minwei Zhang
Extensive antibiotic use has raised concerns over residues in food, necessitating rapid and accurate detection. This study integrates smartphone-assisted deep learning with aptamer-functionalized MIL-101(Fe) nanozymes to build a dual-recognition biosensor capable of simultaneously identifying and quantifying kanamycin (KAN) and kanamycin B (KMB). MIL-101(Fe) exhibited strong adsorption energies and high Langmuir-fitted capacities (28.39 mg/g for KAN; 31.36 mg/g for KMB), indicating monolayer binding at Fe─OH sites that partially suppressed catalytic activity. Aptamer modification enabled selective molecular recognition and accelerated electron transfer, synergistically enhancing nanozyme performance. Coupled with a ResNet-based multitask model, smartphone imaging achieved accurate classification of single and mixed samples and precise quantification over 5–1000 nM. Tests in honey and beef showed recoveries of 84.71%–111.50%, confirming stability and practicality. Overall, the aptamer-enhanced MIL-101(Fe) nanozyme combined with deep learning provides a sensitive, portable approach for on-site monitoring of antibiotic residues in food.
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高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 3
·122658
·
IF 7.5
Meng Yao,Ang Li,Zhilin Ran,Xiaoqing Dong,Ruiyan Xiang,Ting Chen,Gang Liu
Harmful algal blooms threaten drinking water safety. Although ultrafiltration can effectively retain algae cells and algal-derived pollutants, such as extracellular polymeric substances, it still faces challenges such as severe membrane fouling and insufficient contaminant removal. To address these issues, this study developed an integrated “membrane material–flocculant–magnetic regulation” process to enhance algae-laden water treatment and mitigate fouling. Nanoparticles of sulfonated polydopamine (SPDA)-modified Materials of Institute Lavoisier-101 (MIL-101), denoted SPDA@MIL-101, were utilized to functionalize a polyethersulfone (PES) ultrafiltration membrane, enhancing its hydrophilicity and negative surface charge. Meanwhile, a magnetic flocculant (PCNF), composed of polyferric sulfate (PFS), sodium carboxymethyl cellulose (CMC-Na), and iron(II,III) oxide (Fe₃O₄) nanoparticles, was synthesized. Under an external magnetic field, a combined coagulation–ultrafiltration process was employed to actively regulate the cake layer, forming a magnetically responsive cake layer with a graded structure of lower density at the bottom and higher density at the top. The SPDA@MIL-101/PES membrane exhibited significantly improved hydrophilicity, indicated by the reduced contact angle of 54.89°, as well as excellent removal efficiency toward algae-derived fluorescent organic matter. Guided by the magnetic field, the PCNF flocculant formed a loose and porous cake layer, leading to a membrane flux recovery rate of 89% and a reduction in irreversible fouling to 11%. Mechanistic analysis revealed that the magnetic field-mediated dynamic reconstruction of the cake layer optimized the pore network, simultaneously improving contaminant retention and flux recovery performance. This study provides a feasible strategy for the treatment of high-algae water by combining material innovation and process regulation.
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