CATALYSIS LETTERS
·
2022
·Vol. 153
·期 2
·338-347
·
IF 2.936
Xian Liang,Xi Bei,Ma Jing,Gao Xu,Yang YanZhong,Li Wei
Here, well-dispersed and ordered ultrafine Pt nanocatalysts (Pt/SWCNTs) were synthesized by ice-photochemical method on single-walled carbon nanotubes (SWCNTs) without stabilizers and reducing agents. The catalytic performance of Pt/SWCNTs was studied in the reduction of 4 -nitrophenol ( 4 -NP). The morphology and crystal structure of as-synthesized materials were characterized by Fourier transform infrared spectroscopy (FT-IR), X-ray diffraction (XRD), transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS). The prepared samples all contained diffraction peaks of C and Pt with small size and good dispersion by XRD analysis. HR-TEM images displayed that the average particle sizes of the three samples were 1.2 ± 0.2 nm, 1.0 ± 0.2 nm and 1.1 ± 0.1 nm, respectively. The XPS analysis results confirmed the existence of Pt 0 . The catalytic performance test results showed that the prepared Pt/SWCNTs could effectively catalyze the reduction of 4 -NP to 4 -aminophenol ( 4 -AP) with the apparent rate constants of 0.36 min −1 , 0.28 min −1 , and 0.35 min −1 , respectively. Compared with literatures, they all had better catalytic activity. Though after seven cycles, the high catalytic activity was maintained with no significant deactivation and indicating high stability. The experimental results showed that Pt nano-rectangular array catalysts with uniform distribution and ultrasmall particle size were synthesized by a simple freezing method under the irradiation of visible (Vis)/ultraviolet (UV) light. It was demonstrated that the dispersion of Pt(II) reaction intermediates was effectively limited by light induction, carrier-substrate interaction and the use of the natural domain limitation of the ice lattice. Thus controlling the aggregation of Pt(0) to a certain extent and obtaining ordered dispersed ultrafine Pt nanoparticles. This method not only provides a method for the synthesis of ultrafine nanoparticles, but also provides a new idea for single-atom dispersed nanoparticles. Graphical Abstract
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JOURNAL OF FLUORESCENCE
·
2023
·
IF 2.7
Liu Fang,Zhu Changjian,Wang Yingte,Zhang Yong
Carbon dots have been widely focused on the field of sensing and detection due to their excellent optical property. Herein, novel orange fluorescent nitrogen and chlorine co-doped carbon dots (N,Cl-CDs) are obtained by one-pot hydrothermal method using o-phenylenediamine and neutral red. Based on the inner filter effect, the prepared N,Cl-CDs can be innovatively developed as an effective “signal-off” multifunctional sensing platform for sensitive determination of tetracycline. The proposed sensor was utilized to realize the determination of tetracycline in Rirver water samples/milk samples (λex = 390 nm, λem = 606 nm) with satisfactory recoveries and relative standard deviations. The linear range of are 0.05 to 45 μM and 45 to135 μM, and detection limit is 3.9 nM (3σ/m). Meanwhile, the luminescent intensity of N,Cl-CDs was reduced gradually when pH changed continuously from 12 to 2, showing a pH-responsive fluorescence property with two linear ranges of pH 3–7 and pH 7–10. In addition, due to the characteristics of low toxicity and excellent biocompatibility, the N, Cl-CDs were also used in the imaging of oocystis cells, which is hopeful to realize the detection of tetracycline in living cells.
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PubMed
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Nature Communications
·
2026
·
IF 18.1
You Haoyu,Wang Xuemeng,Zhao Denglin,Li Guangyan,Yang Huifang,Bai Jiangxiao,Zou Yatao,Zhang Fei,Debroye Elke,Chen Gaoyu,Xu Weidong
Strong quantum confinement can fundamentally reshape excitonic processes and radiative recombination in perovskite quantum dots (QDs), yet accessing this regime remains challenging in organic-inorganic hybrid FAPbI 3 nanocrystals because of their low crystallization barrier and rapid growth. Here, we report a coordination-mediated cold quenching strategy for synthesizing strongly quantum-confined FAPbI 3 QDs with tunable emission from 696 to 759 nm. The key step involves the injection of a precooled ethyl methacrylate (EMA, –70 °C), which rapidly lowers the reaction temperature while simultaneously retarding precursor conversion and suppressing QD regrowth. Such a strategy enables small QDs with an average size of 6.4 nm and a near-unity photoluminescence quantum yield. Representative light-emitting diodes based on these QDs deliver electroluminescence at 715 nm with a peak external quantum efficiency of 16.3%. This work provides a viable strategy for accessing ultrasmall hybrid perovskite QDs and advances the rational control of quantum confinement in soft ionic semiconductors.
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International Journal of Minerals Metallurgy and Materials
·
2026
·
IF 8.8
She Yanjun,Si Hongxiang,Li Jiaxing,Xu Wenbin,Mamlouk Mohamed,Tian Fang,Anatolyevich Mindrov K.,Wei Tao
A sulfonic-functionalized Zr-type metal–organic framework (UiO-66-SO 3 H) was synthesized, and UiO-66-SO 3 Li was obtained via subsequent lithiation treatment. The UiO-66-SO 3 H framework was incorporated into a polymer matrix as a functional filler to obtain high-performance solid composite electrolytes (SCEs). Structural and morphological analyses, as well as various electrochemical tests, were performed. Owing to well-defined porous channels, abundant lithium-ion transport sites, and effective regulation of polymer crystallinity by SO
− 3
moieties at 60°C, the optimized SCE-2 (10wt% UiO-66-SO 3 Li) exhibited a high ionic conductivity of 5.36 × 10 −4 S·cm −1 (1.86 × 10 −4 S·cm −1 at the room temperature of 25°C), along with a wide electrochemical stability window of 4.7 V and a lithium-ion transference number as high as 0.623. The Li∣SCE-2∣LiFePO 4 full cell exhibited excellent long-cycle stability at both 60°C and room temperature, as well as an excellent rate capability up to 5 C (1 C is equivalent to 170 mA·g −1 ). Moreover, SCE-2 can also be coupled with high-voltage LiNi 0.5 Co 0.1 Mn 0.3 O 2 cathodes. This study demonstrates that sulfonic-modified UiO-66-SO 3 Li can effectively regulate Li + migration, suppress lithium dendrite growth, and enhance interfacial compatibility, offering a viable approach for designing advanced solid composite electrolytes.
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Science China-Chemistry
·
2026
·
IF 9.8
Xu Longyun,Huang Hanjing,Li Conggang,Zhao Huijian,Liu Conghe,Xu Kaidong,Wang Jina,Ye Ning,Hu Zhanggui
Birefringent crystals, which enable precise control and detection of light polarization, are indispensable in advanced laser technologies. However, achieving a birefringence exceeding 0.3 remains a significant challenge. Herein, we report a dual π -conjugated strategy to construct a novel two-dimensional (2D) purely organic sulfonate crystal, (m-AP)(3-pySO 3 ) (denoted as 3PYH; m-AP = m -aminophenol, 3-pySO 3 = 3-pyridinesulfonate), synthesized via a facile solvent evaporation method. 3PYH features a hydrogen-bonded 2D layered architecture assembled from π -conjugated [m-AP] + cations and [3-pySO 3 ] − anions. This crystal exhibits a short ultraviolet (UV) cutoff edge at 271 nm with a wide bandgap of 4.14 eV. Notably, it demonstrates a large visible-region birefringence of 0.36, which is significantly higher than those reported for most 2D sulfates and their derivatives. Combined structural analysis and first-principles calculations reveal that the exceptional birefringence stems from the synergistic enhancement of polarizability anisotropy by dual π -conjugated units, coupled with hydrogen-bond-mediated ordered orientation of aromatic rings, which induces pronounced electron clouds density anisotropy along different directions. This work identifies 3PYH as a promising UV birefringent material and validates the efficacy of the dual π -conjugated strategy for designing sulfonate crystals with strong optical anisotropy.
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高影响因子
Scientific Reports
·
2026
·
IF 4.9
Feng Jiajun,Li Jiawei,Chen Huazheng,Chen Xiaolang,Yu Weili,Jiang Zihong,Huang Qimiao,Chen Lianfen,Li Xiang
Narrow-band green phosphors with tunable decay dynamics have attracted continuous interest for exploring novel luminescent materials. In this work, a series of Ho 3+ -doped sodium yttrium gallium indium germanium garnet (NYGIG) phosphors were synthesized via a conventional high-temperature solid-state reaction route. X-ray diffraction and X-ray photoelectron spectroscopy confirm that Ho 3+ ions are successfully incorporated into the garnet lattice at dodecahedral Y 3+ sites without inducing impurity phases or significant lattice distortion. Under 453 nm blue light excitation, the as-prepared phosphors exhibit intense green emission centered at 548 nm, originating from the 5 S 2 / 5 F 4 → 5 I 8 transition of Ho 3+ , along with a weaker near-infrared emission band at ~ 758 nm assigned to the 5 I 4 → 5 I 8 transition. The green emission intensity reaches its maximum at a Ho 3+ doping concentration of 7 mol%, and the corresponding color purity is calculated to be 83.5%.
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Scientific Reports
·
2026
·
IF 4.9
Song Jiantao,Nie Xinru,Jiang Jun,Zhang Jiuba,Jin Huaijie,Xuan Jianfen,Xue Hui,Su Lianlin,Xia Zongling
Wine-frying is a traditional processing method for Salvia miltiorrhiza ( S. miltiorrhiza ), but the dynamic quality changes during the process lack objective evaluation methods. This study integrates electronic eye, electronic nose, and untargeted metabolomics to analyze the color, odor, and metabolite changes of S. miltiorrhiza during frying. Results showed that, as frying time increases, the color parameter a * decreases, while b * and c * first decrease and then increase. The electronic nose tentatively annotated 20 volatile compounds, with (E)-2-penten-1-ol and acetoin showing significant increases. The orthogonal partial least squares discriminant analysis based on odor successfully distinguished different frying degrees. Untargeted metabolomics annotated 1486 metabolites, among which dihydromacarpine and saponarin were screened as processing-sensitive differential metabolites showing increasing trends with frying time. Volcano plot revealed that frying for 8–12 min was a critical stage for significant metabolite changes. Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis indicated that frying influenced pathways such as isoflavonoid biosynthesis. Correlation analysis established significant relationships between color, odor, and metabolites. A preliminary random forest-based discrimination model was constructed using multi-source fusion variables and optimized by genetic and particle swarm optimization algorithms. The model showed promising internal discrimination performance in the current limited dataset. This study provides a preliminary multi-dimensional framework for evaluating the wine-frying process of S. miltiorrhiza , which requires further validation using larger and more diverse sample sets.
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JOURNAL OF NANOBIOTECHNOLOGY
·
2026
·
IF 15
Liu Shanrui,Li Min,He Peipei,Li Xueying,Zhu Ziwen,Song Jianhao,Li Chunran,Jiang Yujian,Jiao Sizhe,Zhang Jin,Li Xiuwang,Lu Ke,Zhuang Weida,Sang Hongxun
The repair of large-segment bone defects (LSBD) remains a major clinical challenge owing to the hypoxic microenvironment coupled with immune microenvironment dysregulation. Thus, the development of dual-targeting strategies that simultaneously modulate both pathological microenvironments holds great promise for addressing this clinical challenge. In this study, highly catalytically active nanozymes were constructed, which effectively anchored manganese dioxide (MnO 2 ) onto the surface of hydroxyapatite. Subsequently, a low-temperature 3D printing technique was employed to fabricate PLGA/HA@MnO 2 (PHM) composite scaffolds. In vitro experiments demonstrated that the PHM scaffolds potently scavenged endogenous reactive oxygen species (ROS), facilitated localized oxygen release, and ameliorated the osteogenic microenvironment. Concurrently, the PHM scaffolds promote a pro-regenerative osteoimmune microenvironment. Proteomic and functional analyses preliminarily revealed that the PHM scaffolds modulated extracellular matrix composition and integrin receptor expression, thereby activating the integrin αvβ3-mediated focal adhesion signaling pathway, which may promote macrophage TGF-β secretion to facilitate BMSC osteogenesis. In vivo experiments further corroborated the favorable immunomodulatory capacity and pronounced bone repair efficacy. These findings demonstrate that the functional repair of LSBD can be achieved through synergistic regulation of hypoxic and immune microenvironments. This work implicates a potential mechanism through which manganese-based materials modulate the osteoimmune microenvironment and offers a promising strategic framework for the treatment of LSBD. Graphical
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npj Science of Food
·
2026
·
IF 9.7
Zhi Dandan,He Xiying,Yang Linfu,Gong Xueyang,Xue Yunfei,Wang Shuang,Wen Xin,Guan Zhibin,Zhao Hongmu,Dong Kun,Tian Yakai
The incidence of hyperlipidemia, a lipid metabolic disorder, continues to increase globally, but current pharmacological therapies are often limited by adverse effects. Royal jelly acid, a unique monounsaturated fatty acid (MUFA) derived from royal jelly, shows therapeutic promise against hyperlipidemia; however, its direct targets and regulatory mechanisms remain unclear. In a diet-induced rat model of hyperlipidemia, royal jelly acid exhibited favorable safety and significantly improved body weight, serum lipid indices, hepatic enzyme activity, and antioxidant capacity, while alleviating hepatic lipid droplet accumulation. Royal jelly acid significantly increased the abundance of short-chain fatty acid (SCFA)-producing intestinal microorganisms, promoted SCFA production, and restored hyperlipidemia-associated intestinal microbial imbalance. Liver transcriptomic and plasma metabolomic analyses demonstrated that royal jelly acid regulated genes involved in glycolipid metabolism, oxidative stress, and inflammatory responses, as well as multiple key metabolites. Integrated multi-omics analysis and molecular docking confirmed that the glycerophospholipid metabolic pathway represents the core metabolic axis mediating these protective effects. Royal jelly acid mainly alleviates hyperlipidemia by enhancing antioxidant and anti-inflammatory defense through the gut–liver axis–mediated SCFAs–glycerophospholipid pathway. These findings support the use of royal jelly acid as a promising MUFA-based therapeutic strategy for hyperlipidemia and provide a scientific basis for its application.
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ACTA PHARMACOLOGICA SINICA
·
2026
·
IF 10.4
Wang Xiao-ying,Huang Zi-yin,Han Rui,Li Xin-yu,Song Yan-mei,Wang Qi,Xu Fu-you,Zhu Zi-hui,Cheng Rong,Wu Hao-yu,Xia Yi-qing,Ren Hai-gang,Pan Xiao-fan,Xiao Guo-dong,Cheng Jian,Jia Jia
Hypoxia has therapeutic potential, but global hypoxia is toxic. Inducing safe, cell-specific hypoxia remains a clinically unmet need. We hypothesized that small-molecule-augmented oxygen consumption in adjacent cells induces neuron-specific hypoxia, representing a safe ischemic stroke strategy that mimics neural-directed developmental neovascularization. Using single-cell sequencing, a hypoxic probe, and knockout mice, we showed that ADT-OH (an active metabolite of a hepatoprotective drug) targeted sulfide-quinone oxidoreductase (SQR) to increase aerobic respiration in microglia/macrophages, thereby generating neuron-specific hypoxia after cerebral ischemia. Neuronal hypoxia promoted functional angiogenesis by specifically stabilizing hypoxia-inducible factor to upregulate the expression of neuron-derived vascular endothelial growth factor, supporting a neural-directed angiogenic mechanism. ADT-OH also restored the blood–brain barrier (BBB) via microglial/macrophage SQR. Notably, microglia/macrophage UCP2, the downstream mediator of SQR, was required for ADT-OH-induced BBB repair but not angiogenesis. Mechanistically, ADT-OH targeted UCP2 to increase Wnt/β-catenin signaling, which has been shown to mediate developmental BBB formation. In summary, one small molecule targeting SQR achieves therapeutic cell-specific hypoxia.
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高影响因子
WATER AIR AND SOIL POLLUTION
·
2026
·Vol. 237
·期 22
·1265
·
IF 3.5
Yi Linya,Li Weiquan,Li Bing,Wu Jinhua
In this study, simulated Cd(II)-contaminated sediment was incubated under anaerobic conditions for 7 d to evaluate the effect of sulfate-assisted biotic zero-valent iron (Fe 0 ) on Cd(II) immobilization. Microbes such as sulfate-reducing bacteria were employed to potentially facilitate iron corrosion and subsequent mineral formation by consuming cathodic hydrogen generated from anoxic iron corrosion with sulfate serving as an electron acceptor, ultimately enhancing the stabilization of Cd(II) in sediment treated with Fe 0 . Solid-phase analysis demonstrated that sulfate reduction and biological mineralization could promote Fe 0 corrosion, cadmium sulfide production, and secondary mineral generation, thereby enhancing the adsorption and precipitation of Cd(II). After 7 d remediation, the biotic Fe 0 system obtained an efficiency of 82.7% in aqueous Cd(II) removal. It was much higher than that of 15.9% in the abiotic Fe 0 system. Besides, an elevation in sulfate concentration and an increase in Fe 0 dosage both contributed to Cd(II) immobilization, further highlighting the essential role of Fe 0 -assisted sulfate reduction in promoting iron corrosion and Cd(II) stabilization. Results from sequential extraction and leaching test revealed a significant decline in Cd(II) leachability by 81.4%, concomitant with a substantial increase in residual Cd(II) fraction by 151.2% as compared to the untreated sediment. This study provided a scientific foundation for a deep insight into the environmental behavior of sulfate in stabilizing Cd(II) through biotic Fe 0 in sediments and for the development of efficient heavy metal detoxification technologies.
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3 Biotech
·
2026
·Vol. 16
·期 10
·435
·
IF 3.1
Liu Haixia,Jiang Xinhui,Jiang Min,Wen Hailan,Zheng Jiabin,Lan Chengmu,Jiang Mingfu,Qin Zhijie,Chen Lei
Oysters are an abundant marine protein resource with strong potential for generating bioactive peptides. In this study, an integrated strategy combining ultrasound pretreatment with response surface methodology–optimized enzymatic hydrolysis was developed to efficiently produce functional peptides from Crassostrea gigas . Ultrasound-assisted hydrolysis markedly improved peptide yield and promoted the formation of low-molecular-weight peptides, with fractions < 3 kDa accounting for 83.7% of the hydrolysate. Structural characterization revealed that the resulting peptides were enriched in hydrophobic and aromatic amino acids and exhibited increased conformational flexibility with reduced ordered secondary structures. Functionally, oyster peptides demonstrated strong in vitro antioxidant activity, including effective radical scavenging and ferric-reducing capacity. In cellular models, the peptides significantly alleviated hydrogen peroxide (H₂O₂)-induced oxidative stress in HepG2 cells by reducing intracellular reactive oxygen species (ROS), enhancing endogenous antioxidant enzyme activities, and suppressing lipid peroxidation. Furthermore, in differentiated C2C12 myoblasts, the peptides improved cellular energy metabolism under oxidative challenge, as evidenced by increased ATP levels and reduced LDH release, indicating promising anti-fatigue potential. Collectively, the resulting peptides reduced ROS accumulation in HepG2 cells and increased ATP levels in C2C12 myotubes, supporting their potential as antioxidant and cellular energy metabolism-supporting ingredients.
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高影响因子
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