SOLAR ENERGY MATERIALS AND SOLAR CELLS
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2019
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IF 6.019
Xusheng Zhang,Zheng Du,Yudong Zhu,Chuan Li,Xianfeng Hu,Tingbin Yang,Bin-Bin Yu,Rui Gu,Yulong Ding,Zhubing He
Low-medium temperature phase change materials (PCMs) act as a predominant role in one-sun solar thermal energy conversion and storage, attracting increasing attention in recent years. However, highly thermal conductive PCMs relying on the doping of a high dose of thermally conductive particles would limit the light absorption just at its top surface and decrease its bulk thermal storage density. In this work, we designed a volumetric solar absorber integrated with a D-Mannitol (DM) based PCM loaded with a low concentration (0.05 wt%) of acetylene black nanoparticles other than a high concentration of over 5 wt%. Such a method maintains a high phase change enthalpy of DM (295.2 kJ/kg) while achieving an enhanced heat transfer and hence a uniform temperature distribution . Compared to conventional surface absorbers with PCM, the volumetric absorber significantly reduces the temperature difference inside the bulk materials, from 103.1 °C of the surface absorber to 62.7 °C of the volumetric absorber with a thickness of 10 mm. Their photo to thermal charge and discharge performance was investigated for the first time in their based solar thermoelectric generator (STEG) system, which show that the volumetric absorber could reach 198.2 °C on bottom of the PCM and the corresponding open circuit voltage is 0.65 V. Such performance data are significantly better than the corresponding results from the surface absorber of 135.1 °C and 0.45 V, respectively, demonstrating successfully the significant performance enhancement by our volumetric absorber. This paper definitely deepens our understanding of volumetric absorbers and their based device design and applications in solar-thermal-electricity systems.
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CERAMICS INTERNATIONAL
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2020
·Vol. 46
·期 13
·20810-20818
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IF 3.83
Mengjing Liu,Sun-Wai Chiang,Xiaodong Chu,Jia Li,Lin Gan,Yanbing He,Baohua Li,Feiyu Kang,Hongda Du
Herein, oriented boron nitride (BN)/alumina (Al 2 O 3 )/polydimethylsiloxane (PDMS) composites were obtained by filler orientation due to the shear-inducing effect via 3-D printing. The oriented BN platelets acted as a rapid highway for heat transfer in the matrix and resulted in a significant increase in the thermal conductivity along the orientation direction. Extra addition of spherical Al 2 O 3 enhanced the fillers networks and resulted in the dramatic growth of slurry viscosity. This, together with filler orientation induced the synergism and provided large increases in the thermal conductivity . A high orientation degree of 90.65% and in-plane thermal conductivity of 3.64 W/(m∙K) were realized in the composites with oriented 35 wt% BN and 30 wt% Al 2 O 3 hybrid fillers. We attributed the influence of filler orientation and hybrid fillers on the thermal conductivity to the decrease of thermal interface resistance of composites and proposed possible theoretical models for the thermal conductivity enhancement mechanisms.
研究领域:
材料科学
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高分子化学
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热管理材料
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先进制造
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复合材料工程
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INTERNATIONAL IMMUNOPHARMACOLOGY
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2026
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IF 5.6
Shangmin Yu,Jiaqi Liu,Shan Liu
Background Atherosclerosis (AS) is a chronic inflammatory vascular disease. Macrophage reprogramming plays a crucial role in the progression of AS. Ophiopogonin D (OP-D), a bioactive constituent of Ophiopogon japonicus , has exhibited potent anti-atherosclerotic property. However, whether OP-D exerts its atheroprotective effect via reprogramming macrophage remains unclear. This study aimed to investigate the effect of OP-D on AS and elucidate its underlying mechanism. Methods The atheroprotective effect of OP-D on atherosclerotic mice was evaluated by histological and molecular assays. The crucial role of macrophage in OP-D's atheroprotective effect was detected by flow cytometry and verified through macrophage depletion/infusion. The direct effect of OP-D on macrophages were assessed in vitro by RT-qPCR, flow cytometry, and immunofluorescence. RNA sequencing and amino acid-targeted metabolomics analysis were employed to identify the associated amino acid metabolic pathways. In addition, PPM1K deficient was established to validate the role of branched-chain amino acids (BCAAs) in macrophage reprogramming and OP-D's therapeutic effect. Results Our results demonstrated that OP-D attenuated the progression of AS and directly prevented the M1-like polarization of macrophages. Meanwhile, the therapeutic benefits of OP-D were abolished after macrophages depletion, suggesting macrophage was a crucial mediator of OP-D's therapeutic effect. Further mechanistic studies revealed that dysregulated BCAAs metabolism-mediated macrophage polarization underlay the anti-atherosclerotic effect of OP-D. Conclusion This study elucidated that OP-D reprogrammed the polarization of macrophages through modulating BCAAs catabolism to delay atherogenesis. These findings will deepen the understanding of OP-D's atheroprotective mechanisms and provide a potential therapeutic target for AS.
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PubMed
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ACS Catalysis
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2026
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IF 13.6
Xing Yu,Peng Deng,Sheng Gu,Bu-Bing Zeng,Hui-Lei Yu,Jian-He Xu,Zhi-Jun Zhang
Direct asymmetric α-C−H bond amination of carboxylic acids is an attractive route to optically active α-amino acids from inexpensive, renewable starting materials. However, traditional chemical methods suffer from expensive catalysts and environmental concerns, while recently developed multienzyme cascades are limited by complex auxiliary enzyme requirements and narrow substrate scope. Here, we report an engineered P450 peroxygenase (P450CLA-M5) with enhanced overoxidation promiscuity that enables the direct conversion of fatty acids to α-keto acids. Coupling this enzyme with d-amino acid dehydrogenase and formate dehydrogenase establishes a biocatalytic cascade for the C−H amination of fatty acids to d-amino acids. Saturated, unsaturated, and aromatic fatty acids were converted to the corresponding d-amino acids with yields up to 94% and >99% ee. Specifically, the yield of d-2-aminodecanoic acid represents a 15-fold improvement over previous biocatalytic approaches. This work demonstrates how engineering increased enzyme promiscuity can enhance cascade efficiency for the synthesis of valuable chiral d-amino acids from renewable feedstocks.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2023
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IF 22.1
Sundaram Chandrasekaran,Tingting Ma,Zhichang Hu,Qianying Liu,Chao Zhan,Yan Li,Chris Bowen,Huidan Lu,Yongping Liu
Chevrel-phase metal sulfides are known to be promising materials for energy conversion and storage applications. However, a detailed understanding of the intrinsic kinetic mechanisms of electrocatalytic bifunctional hydrogen and oxygen evolution reactions (HER/OER) on NiMo 3 S 4 -based Chevrel-phases is lacking. Herein, novel ultrathin self-assembled nanosheets of NiMo 3 S 4 are coupled with transition metal atoms (M/N-NiMo 3 S 4 ; where M = Co, Fe, and Cu) were formed by a facile hydrothermal approach. Notably, the Co/N-NiMo 3 S 4 electrocatalyst exhibits excellent performance in terms of ultralow overpotentials of 78, 208, 282, and 307 mV at 10, 100, 500, and 1000 mA cm −2 for the HER; and 186, 204, and 225 mV at 50, 100, and 300 mA cm −2 for the OER, respectively. Experimental and first principle calculations demonstrate that Co atoms coupling with edge Ni atoms results in d‐electron delocalization on Co/N-NiMo 3 S 4 , signifying the efficient charge transfer to improve overall water electrolysis. In addition, an upshift in the d‐band center of Co/N-NiMo 3 S 4 can optimize the free energies of a variety of reaction intermediates for water adsorption and dissociation; thereby facilitating the robust alkaline overall water electrolysis at 1.47 V. This work therefore greatly deepens the understanding of the bifunctional hydrogen and oxygen evolution reaction of Chevrel-phase electrocatalysts.
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APPLIED CATALYSIS B-ENVIRONMENTAL
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2023
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IF 22.1
Xiaofei Liu,Tianxing Wang,Yilin Chen,Jingtao Wang,Wenjie Xie,Rongqian Wu,Xingtao Xu,Lihui Pang,Xiaogang Zhang,Yi Lv,Guangzhao Wang,Yusuke Yamauchi,Tian (Leo) Jin
Orbital hybridization is a powerful tool for modulating electronic structures toward various electrocatalytic reactions. Compared to the widely reported d - d hybridization in d -block metal alloys, the p - d orbital hybridization between d -block metals and p -block elements could provide new opportunities for regulating the electronic properties and thus promoting the electrocatalytic activities. Herein, we report a distinctive p -block metalloid-regulating p - d orbital hybridization to realize the fabrication of RuSb nanobranches for bifunctional hydrogen evolution (HER) and hydrazine oxidation (HzOR), which exhibits huge potential in overall hydrazine splitting (OHzS) by utilizing thermodynamically favorable HzOR instead of sluggish oxygen evolution on the anode. To our delight, RuSb delivers an impressively low overpotential of 39 mV for HER and 252 mV for HzOR at 10 mA cm −2 in alkaline seawater. The two-electrode OHzS electrolyzer with RuSb||RuSb couple can achieve outstanding electrocatalytic activity with an extraordinarily small cell voltage of 35 mV to drive 10 mA cm −2 in alkaline seawater, outperforming the Pt/C||Pt/C couple under the same condition. Density functional theory calculations further indicate that the Sb doping can not only mediate the adsorption energy for hydrogen but also the energy barrier for the dehydrogenation of *N 2 H 3 . Therefore, our work verifies the huge potential of p - d orbital hybridization for the development of a bifunctional OHzS system in alkaline seawater.
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Pharmaceuticals
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2021
·Vol. 14
·期 11
·1194
·
IF 5.863
Min Li,Qingfeng He,Li Yao,Xiaofeng Wang,Zhijia Tang,Xiao Zhu,Hai-Shu Lin,Xiaoqiang Xiang
Propylthiouracil (PTU) is commonly prescribed for the management of hyperthyroidism and thyrotoxicosis. Although the exact mechanism of action is not fully understood, PTU is associated with hepatoxicity in pediatric population. Glucuronidation mediated by uridine 5′-diphospho-glucuronosyltransferases (UGTs), which possess age-dependent expression, has been proposed as an important metabolic pathway of PTU. To further examine the metabolism of PTU, a reliable HPLC-MS/MS method for the simultaneous quantification of PTU and its N-β-D glucuronide (PTU-GLU) was developed and validated. The chromatographic separation was achieved on a ZORBAX Extend-C18 column (2.1 × 50 mm, 1.8 μm) through gradient delivery of a mixture of formic acid, methanol and acetonitrile. The electrospray ionization (ESI) was operated in its negative ion mode while PTU and PTU-GLU were detected by multiple reaction monitoring (MRM). This analytical method displayed excellent linearity, sensitivity, accuracy, precision, recovery and stability while its matrix effect and carry-over were insignificant. Subsequently, the in vitro metabolism of PTU was assessed and UGT1A9 was identified as an important UGT isoform responsible for the glucuronidation of PTU. The information obtained from this study will facilitate future mechanistic investigation on the hepatoxicity of PTU and may optimize its clinical application.Keywords:propylthiouracil;propylthiouracil glucuronide;in vitro;human liver microsomes;UGT1A9;HPLC-MS/MS
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JOURNAL OF SOLID STATE CHEMISTRY
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2021
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IF 3.498
Ping-Ping Sun,Yu-Hang Zhang,Hongwei Shi,Fa-Nian Shi
A new 3-D Co-MOF with the molecular formula of C 10 H 8 Co 3 N 4 O 12 was prepared by hydrothermal method . As the anode for lithium ion battery , the electrode modified with 20% copper powder (Co-MOF-20) shows the specific capacity of 1138.5 mAh g −1 at 100 mA g −1 . Even under the high current test of 500 mA g −1 , Co-MOF-20 also shown excellent performance (349.6 mAh g −1 ) after 300 cycles. The advantages of Co-MOF-20 electrode are not only due to the introduction of copper powder conductive agent, but also the existence of three-dimensional structure which can provide ion transport channels.
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Small
·
2021
·Vol. 18
·期 4
·2105696
·
IF 13.281
Qiming Chen,Ning Gong,Tanrui Zhu,Changyu Yang,Wenchao Peng,Yang Li,Fengbao Zhang,Xiaobin Fan
The oxygen evolution reaction (OER) plays a key role in many electrochemical energy conversion systems, but it is a kinetically sluggish reaction and requires a large overpotential to deliver appreciable current, especially for the non-noble metal electrocatalysts. In this study, the authors report a surface phase engineering strategy to improve the OER performance of transition metal nitrides (TMNs). The iron-nickel nitrides/alloy nanospheres (FeNi 3 -N) wrapped in carbon are synthesized, and the optimized FeNi 3 -N catalyst displays dual-phase nitrides on the surface induced by atom migration phenomenon, resulting from the different migration rates of metal atoms during the nitridation process. It shows excellent OER performance in alkaline media with an overpotential of 222 mV at 10 mA cm −2 , a small Tafel slope of 41.53 mV dec −1 , and long-term durability under high current density (>0.5 A cm −2 ) for at least 36 h. Density functional theory (DFT) calculations further reveal that the dual-phase nitrides are favorable to decrease the energy barrier, modulate the d-band center to balance the absorption and desorption of the intermediates, and thus promote the OER electrochemical performance. This strategy may shed light on designing OER and other catalysts based on surface phase engineering.
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PROCESS BIOCHEMISTRY
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2019
·
IF 2.883
Ping Zhu,Yan Zeng,Peng Chen,Yan Men,Jiangang Yang,Xiaoping Yue,Jiangang Zhang,Yueming Zhu,Yuanxia Sun
A one-pot two-enzyme reaction system was developed to produce high-fructose syrup (HFS) containing healthy rare sugar d-allulose from Jerusalem artichoke (JA). Inulin in JA was converted through the cascade reaction of a novel exo-inulinase from Bacillus velezensis (BvInu) and D-allulose 3-epimerase from Ruminococcu s sp. (RDAE). BvInu and RDAE were expressed in Bacillus subtilis and successfully secreted into the supernatant, which decrease the production cost and avoid enzyme purification. The optimal temperature and stability of extracellular BvInu significantly increased, thereby promoting the catalytic activity of the two enzymes for the cascade reaction in one pot. Inulin in JA powder was almost completely converted into monosaccharides in the treatment with the optimal ratio of BvInu : RDAE (80 : 40 U/g inulin) at 50 °C for 2 h. The ratio of D-glucose, D-fructose, and D-allulose in the product was approximately 1:3:1, and the yield on JA powder was 67%. The system exhibits potential high-valued application of non-grain crops on producing HFS with D-allulose.
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INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
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2019
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IF 4.084
Xiaorong Zhang,Muhammad Shakeel,Baoshan Li,Muhammad Arif,Xianglong Kong,Jianjun Liu,Shengli Zuo
The present study is about the fabrication of an efficient photo-/electrocatalyst, prepared via in-situ hydrothermal coupling of ZnO with g-C 3 N 4 . The results prove this electrocatalyst as suitable band structure semiconductor. The crystalline nature and related morphological parameters are controlled by optimized hydrothermal and calcination temperatures conditions. A series of physicochemical characterization are applied to inquire the crystalline structure, surface morphology , optical capabilities and charge transportation properties. Results revealed that the sample acts as excellent electrocatalyst with OER current density at 10 mAcm −2 @ 335 mV and the HER at 100 mAcm −2 @ −225 mV. While upon illuminations its catalytic properties further enhance at OER 10 mAcm −2 @ 326 mV and for HER current density of 100 mAcm −2 @ −167 mV. It can be seen from the present study that g-C 3 N 4 play gigantic role in enhancing the catalytic property of ZnO and hence it leads to a relationship between hierarchical features and photo-/electrochemical activity for water splitting.
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BIOMACROMOLECULES
·
2015
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IF 5.75
Piming Ma,Long Jiang,Pengwu Xu,Weifu Dong,Mingqing Chen,Piet J. Lemstra
In this work we report the in situ preparation of fully biobased stereocomplex poly(lactide) (SC-PLA) nanocomposites grafted onto nanocrystalline cellulose (NCC). The stereocomplexation rate by compounding high-molar-mass poly(d-lactide) (PDLA) with comb-like NCC grafted poly(l-lactide) is rather high in comparison with mixtures of PDLA and PLLA. The rapid stereocomplexation was evidenced by a high stereocomplexation temperature (Tc-sc = 145 °C) and a high SC crystallinity (Xc-sc = 38%) upon fast cooling (50 °C/min) from the melt (250 °C for 2 min), which are higher than currently reported values. Moreover, the half-life crystallization time (175–190 °C) of the SC-PLA was shortened by 84–92% in comparison with the PDLA/PLLA blends. The high(er) stereocomplexation rate and the melt stability of the SC in the nanocomposites were ascribed to the nucleation effect of the chemically bonded NCC and the “memory effect” of molecular pairs in the stereocomplex melt because of the confined freedom of the grafted PLLA chains.
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