Journal of Water Process Engineering
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2024
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IF 6.3
Jingmin Yan,Zhengchen Li,Licheng Ma,Peiwei Han,Wenkai Zhao,Shufeng Ye
In this study, a highly efficient CuO/α-MnO 2 bimetallic catalyst was synthesized by hydrothermal and calcination methods and employed as a peroxydisulfate (PDS) activator for the degradation of thiocyanate (SCN − ) in aqueous phase. The effect of calcination temperature on the catalytic performance of CuO/α-MnO 2 and the mechanism of the CM350/PDS system were studied. Under optimal conditions, almost 100 % of SCN − (100 mg/L) was degraded within 90 min. XRD , XPS , Raman, and H 2 -TPR analyses revealed that the catalytic performance was enhanced in the CM350 catalyst due to the formation of M-O-Cu + -like structures (M = Mn 3+ , Mn 4+ , Cu 2+ ) through the combination of α-MnO 2 with CuO . The structures exhibit excellent redox ability and facilitate electron transfer between Cu and Mn elements, thereby improving the activation effect of PDS. Besides, the Cu 1.5 Mn 1.5 O 4 generated from the high calcination temperature was not conducive to the SCN − degradation reaction. Moreover, the mechanism study indicated that SO 4 ·- , ·OH, and the electron transfer pathway mainly accounted for the SCN − degradation. This study provides some guidance for the synthesis of PDS activation materials and the treatment of industrial wastewater by an advanced oxidation process .
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MICROCHEMICAL JOURNAL
·
2024
·
IF 4.9
Hong-Jiao Zhang,Li-Wei He,Ke-Min Dong,Song-Yuan Li,Can Luo,Jia-Qi Han,Rui Li
The development of simple, selective and sensitive analytical methods to effectively monitor α-glucosidase (α-Glu) and discover its new inhibitors is very critical for the diagnosis and treatment of diabetes. Herein, an autofluorescence-free sensing method based on β-cyclodextrin (β-CD) functionalized persistent luminescence nanoparticle (PLNP) is established for the detection of α-Glu activity and its inhibitor. The p-nitrophenol (PNP) produced by the hydrolysis of substrate p-nitrobenzene-α-D-glucopyranoside (PNPG) by α-Glu in the system can be selectively captured by the β-CD on the nanoprobe to form adducts through the host guest effect between them, resulting in persistent luminescence quenching due to electron transfer (ET) effect. The proposed method provides a good linear relationship within the range of 5–80 U/L and a low detection limit of 0.9 U/L, and can detect α-Glu in human serum with the recovery rate of 95.4–103.3 %. Furthermore, the detection system can measure the inhibitory ability of acarbose with an IC 50 value of 349 μM, proving its good potential for application.
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Molecular Catalysis
·
2024
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IF 3.9
Tao Lv,Kexin Wei,Ting Wang,Xiao Wang,Zuguang Liu
A carbon-based acid was prepared by the sulfonation of activated carbon derived from eucalyptus wood waste, a solid waste from wood processing, and characterized by SEM, BET, FT-IR, Raman, XRD and XPS. Due to activation by phosphoric acid and subsequent sulfonation, the resultant carbon-based solid acid can obtain a porous structure, medium surface area and abundant functional groups including sulfonic groups, carboxyl, hydroxyl and other oxygen-containing groups, which provides excellent mass transfer channels and sufficient reactive sites for catalytic reactions. So, the carbon-based solid acid showed excellent catalytic performance for converting α -pinene to camphene with a conversion of up to 99.8 % and a selectivity of 51.2 %, respectively. Quantum chemical theoretical calculations (electrostatic potential, Gibbs free enthalpy of intermediates, molecular size) are used to further analyze the catalytic mechanism of carbon-based solid acids. Theoretical analysis of the carbon positive ions and their energies as well as experimental results under electron-donating co-catalysts suggests that oxygen-containing functional groups on carbon-based solid acids play an important role in improving α- pinene adsorption onto catalyst as well as camphene selectivity. This work provides a promising approach for converting α -pinene to camphene catalyzed by carbon-based solid catalyst.
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FOOD CHEMISTRY
·
2025
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IF 9.8
Lichun Liu,Ziye Zhang,Wei Yang,Fatih Özogul,Zhenxing Li,Hong Lin
α-dicarbonyl compounds are widely present in foods, while their modification effects on food allergens are unclear. This work was conducted to investigate the effects of α-dicarbonyl compounds (glyoxal (GO), methylglyoxal (MGO) and 2, 3-butanedione (BU)) on the digestive stability and intestinal flora of shrimp tropomyosin (TM). As the results, higher α-dicarbonyl concentration, longer time and higher temperature could exacerbate the modification of TM. Compared with TM, GO and MGO significantly reduced the digestive resistance of TM and the IgG-binding capacity of AGEs-TM digests. Although in vitro digestion reduced IgE-binding capacity of TM/AGEs-TM, in vivo evidence (intestinal biopsy and gut microbiota) suggested that they still elicits immune responses. In addition, AGEs-TM could reduce the richness and diversity of intestinal flora, increase the abundance of inflammation-related flora and flora imbalance index, which could provide a new insight into the effects of AGEs on the digestive stability of shrimp tropomyosin and intestinal microbiota.
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Journal of Environmental Chemical Engineering
·
2025
·
IF 7.2
Yuxi Li,Zhuwei Zhu,Ximai Zhang,Fengkuan Ma,Qiaohong Zhang,Chen Chen,Hongying Lü
Selective oxidation of hydrocarbon under mild conditions is one of scientific challenges. In the present work, facet effect was utilized to design an efficient catalytic system of N -hydroxyphthalimide (NHPI) and specific α-Fe 2 O 3 with different preferential crystal facets. Higher ratio of crystalline facet {110}/{104} was identified as a key factor to facilitate the interaction between NHPI molecules and surface of α-Fe 2 O 3 , then realize a higher catalytic activity. Being photo-irradiated with the blue light (455 nm, 3 W) at ambient temperature for 4 h, conversion of 92.2% was obtained for the selective oxidation of ethylbenzene with α-Fe 2 O 3 -T100 that owns more preferential crystalline facets {110}, which is about 1.8 times as high as that (51.0%) being obtained with commercial C-α-Fe 2 O 3 -{104}. The present efficient catalytic system also exhibited good universality for the selective oxidation of a series of other hydrocarbons.
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Journal of Environmental Chemical Engineering
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2025
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IF 7.2
Che Han,Yujie Wang,Jintao Liu,Qiangyi Deng,Hongmei Zhang,Shuang Xu,Conglu Zhang
There is growing attention in the removal of microplastics (MPs) from aquatic environment because of their toxicity and difficulty in degradation. Magnetic Fe 3 O 4 is a potential material for MP removal, however, for fabrication of high-efficiency Fe 3 O 4 -based adsorbents, the alkaline synthesis conditions and weak affinity toward MPs must to be addressed. In this study, we developed magnetic α-Fe 2 O 3 /Fe 3 O 4 hybrid adsorbents (MFes) with engineered affinity sites via a facile one-pot synthesis method. During the material formation process, melamine acted as both a nitrogen source for creating N-modified polar adsorption sites and an inducer for formation of α-Fe 2 O 3 /Fe 3 O 4 phase interfaces. The α-Fe 2 O 3 /Fe 3 O 4 phase interfaces provided additional active sites, as evidenced by the enhanced microplastic adsorption performance. The MFe-1.6–100 achieved 92.3 % polystyrene removal at low adsorbent dosage 0.2 g L −1 and showed rapid adsorption kinetics within 25 min, which is superior to most reported values. After five cycles, the removal efficiency could still retain 90 %. Additionally, MFe-1.6–100 exhibited remarkable ion-tolerance for Cl - and NO 3 - . These performances suggest its potential applicability for MPs capture in aquatic environments.
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CERAMICS INTERNATIONAL
·
2025
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IF 5.6
Dazhao Liu,Ting Fang,Kaixuan Gui,Miao Wang,Wengang Zhang,Dongyang Zhang
In this study, α-Al 2 O 3 platelets with controlled size and uniform thickness were successfully synthesized at 900 °C using a molten salt synthesis method. The effects of calcination temperature, holding time, molten salt and additive concentration on the morphology, particle size, and phase composition of α-Al 2 O 3 were systematically investigated. The results revealed that calcination temperature significantly influenced the particle size and platelet morphology, with higher temperatures leading to larger particles and more irregular structures. Prolonged calcination time increased both the diameter and thickness of the platelets. The content of molten salts and Na 3 PO 4 was critical in regulating platelet uniformity and growth. An appropriate amount of TiCl 4 facilitated the formation of a flake-like structure. This work provides valuable insights into the tailored synthesis of α-Al 2 O 3 platelets, offering a cost-effective method for producing advanced materials with potential applications in various fields.
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MICROCHIMICA ACTA
·
2025
·Vol. 192
·期 9
·1-10
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IF 5.3
Wang Feifei,Wang Xinling,Wang Yu,Zhang Yin,Liu Tianxiang,Sun Jian
A novel and facile fluorescence turn-on assay for detecting α-glucosidase (α-Glu) activity and screening inhibitors is reported. This assay exploits α-Glu-catalyzed hydrolysis of L-ascorbic acid-2-O-α-D-glucopyranosyl (AA2G) to release ascorbic acid (AA), triggering an in situ fluorogenic reaction with N-methylethylenediamine (N-MEDA) that generates non-conjugated polymer dots (NCPDs). These NCPDs emit blue fluorescence at 425 nm upon excitation at 350 nm, and the fluorescence intensity increases proportionally with the concentration of α-Glu, enabling quantitative detection of enzymatic activity. The fluorescent assay demonstrates a linear response ranging from 0.01 to 10 U/mL and achieves a low detection limit of 0.0034 U/mL, surpassing most existing methods in sensitivity and width of linear range. In addition, the proposed method has been successfully applied to screen α-Glu inhibitors (AGIs) and determine α-Glu activity in real samples, yielding satisfying results. This work introduces a robust analytical framework and promising approach for clinical diagnosis and anti-diabetic drug discovery. Graphical
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
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2025
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IF 6.2
Tengyi Du,Ruofei Bai,Yiwei Wang,Zijian Zhao,Congwei Zhou,Yuhao Zhang,Bingyi Xie,Dongmei She,Bohang Zhou,Le Zhou
As part of our continuing investigation on hydrazide antifungal agents, a series of N’-aryl hydrazide derivatives of α,β-unsaturated fatty acids were designed and explored for their inhibitory activity on various phytopathogenic fungi and their mechanism. Most of the compounds showed excellent activity, with average EC50 values of 0.76–5.79 μg/mL on A. solani, A. brassicae, A. alternate, C. gloeosporioides, and P. oryzae. Among N’-substituted phenyl hydrazide derivatives of senecioic acid, 4-fluoro (5a), 4-bromo (5g), 3-cholor-4-fluoro (5s) and 3,4-dicholor (5w) derivatives displayed average EC values of 0.76–0.87 μg/mL on the five fungi, far superior to 2.99 μg/mL of kresoxim-methyl, a commercial fungicide. Especially, 5s was able to completely inhibit the growth in vitro of all the fungi at 20 μg/mL and gave almost the same control effect as the positive fungicide boscalid against the infection of tomato fruits by A. solani at 200 μg/mL. Meanwhile, 5s did not display a visible effect on plant seed germination at 200 μg/mL and seedling growth at 100 μg/mL, nor significant cytotoxicity on normal L929 mouse fibroblasts at 1.0 mg/mL. Scanning electron microscopy, transmission electron microscopy, and fluorescence microscopy studies revealed that 5s could destroy the mycelial morphology and the structure of the cell membranes, increase the ROS level in cells, alter the MMP, and cause cell death. Additionally, 5s could also strongly inhibit the activity of SDH in A. solani, with an IC50 value of 3.54 μg/mL, superior to 4.46 μg/mL of the positive SDHI boscalid. Molecular docking showed that the 4-fluoro group of the benzene ring plays an important role in the binding of 5s to SDH. The SAR indicated that the presence of a 4-halogen atom on the benzene ring is able to dramatically improve the antifungal activity. The N’-aryl hydrazides of α,β-unsaturated fatty acids emerged as novel and promising antifungal lead compounds.
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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
·
2024
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IF 7.7
Hongxi Zhang,Zhongke Li,Xiande Yang,Meng Li,Liang Wei,Jing Yang
Lignin is anticipated to serve as a replacement for dwindling fossil fuel resources owing to its abundant sources and renewable nature. The electrochemical oxidation technique for depolymerizing lignin has garnered significant interest for its environmentally friendly and mild operating conditions. Nevertheless, the current utilization of auxiliary electrolytes, predominantly organic bases, ionic liquids, and other specialized substances, poses a constraint on the widespread adoption of this approach. Furthermore, there is a scarcity of instances where electrochemical technology has been employed to depolymerize the α-O-4 bond in lignin for the production of highly selective acetals. In this study, a sodium chloride/methanol (NaCl/MeOH) system was utilized for the direct depolymerization of the α-O-4 bond in a lignin model molecule, specifically benzyl phenyl ether (BPE). The optimal conditions resulted in a 95.2 % conversion rate of the BPE substrate and a high yield of 94.5 % for the main product, benzaldehyde dimethyl acetal(Bda). This research offers a promising approach for the electrocatalytic depolymerization of α-O-4 bonds in lignin, leading to the selective production of acetal chemicals using a common auxiliary electrolyte at room temperature in just 2 h.
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Small
·
2025
·
IF 12.1
Liyuan Zhao,Yujuan Cao,Yanru Xin,Chenxi Liu,Jin Yang,Yanan Li,Sidan Tian,Zhenxing Liu,Haibo Jia,Mugen Liu,Min Hu,Liang Luo,Fanling Meng
α-Synuclein (α-Syn) amyloidogenesis is considered a promising diagnostic marker and therapeutic target for Parkinson's disease (PD). Simultaneously visualizing and mitigating α-Syn amyloidogenesis are essential for future PD theranostics, yet they continue to pose an insurmountable challenge. This study have herein developed a nanobody-decorated polydiacetylene to approach a straightforward solution. Grafting α-Syn61-95 segment into the third complementary determining region of a parent nanobody generates an engineered nanobody X30 that can bind with α-Syn and prevent its amyloidogenesis through homotypic interaction. It next use X30 to decorate poly(deca-4,6-diynedioic acid) (PDDA), a polydiacetylene with an ultrastrong alkyne Raman signal (2120 cm −1 ) in the cellular silent region, to create an α-Syn targeting Raman probe PX30. The binding affinity between X30 and α-Syn can be further boosted for over 150 times attributed to the rigidity of PDDA backbone and the multivalent effect. Therefore, PX30 not only enables real-time Raman visualization of α-Syn amyloidogenesis with a high signal-to-noise ratio in living zebrafish, but also alleviates amyloidogenesis-mediated damage to zebrafish embryos by effectively inhibiting α-Syn amyloidogenesis at low stoichiometric concentrations and scavenging pathologic reactive oxygen species.
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IONICS
·
2025
·
IF 2.6
Wang Zhaomin,Zhao Chaoyue,Niu Xiaodong,Cheng Yong,Wang Limin,Huang Pai
With high theoretical discharge specific capacity, excellent reversibility of electrochemical reaction, and suitable oxygen evolution overpotential, α -Ni(OH) 2 is an auspicious cathode material for alkaline batteries, which supports the development of high-capacity nickel-based batteries. Nevertheless, α -Ni(OH) 2 exhibits substandard structural stability and is susceptible to crystalline transformation, leading to capacity degradation, affecting the battery charge/discharge performance and cycle life. In this study, the TiO 2 -nickel hydroxide (TiO 2 - α -Ni(OH) 2 ) is prepared by high-energy ball milling. Among them, TiO 2 can be uniformly dispersed on the surface of α -Ni(OH) 2 , which can effectively prevent the collapse of the α -phase structure. Benefiting from the unique elemental doping technology, the TiO 2 - α -Ni(OH) 2 composites as a nickel-metal hydride (Ni-MH) battery cathode can release a reversible specific capacity of 390 mAh g −1 at a 2 C rate for 200 cycles. A reversible specific capacity of 210 mAh g −1 is still released after 200 cycles at a 5 C rate. Consequently, TiO 2 - α -Ni(OH) 2 is a promising candidate for high-power Ni-MH batteries.
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