COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2025
·
IF 5.4
Minqiang Xia,Yulu Ye,Zihan Jiang,Yunbo Li
The rapid industrial growth has resulted in a surge in organic coloring agent contaminating water bodies, necessitating urgent environmental remediation. In this work, we present a facile approach for synthesizing degradable thiourea-2-polycaprolactone (T2P) to anchor gold nanoparticles (AuNPs) via filtration, aimed at AuNPs membranes with enhanced efficient catalytic activation. T2P anchored AuNPs membranes demonstrate exceptional stability and catalytic efficiency. They efficiently catalyzes the reduction of 0.1 mM solutions of 4-nitrophenol, methyl orange, and methylene blue in 330 sec, 8.0 min, and 3.0 min, respectively, while achieving the reduction of 10 −4 M 2-nitrophenol takes only 240 sec. Remarkably, even after 15 catalytic cycles, the membrane maintains its original catalytic performance at an efficiency of 100 %, owing to the abundance of active sites facilitated by the preparation method. This novel approach of fabricating degradable T2P anchored AuNPs membranes sets a precedent for sustainable, high-performance catalysts, laying a foundation for economic, eco-friendly catalyst development.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF ALLOYS AND COMPOUNDS
·
2025
·
IF 6.3
Chunyan Fan,Xuxin Song,Yao Tang,Zehao Zang,Yangyang Ren,Lanlan Li,Xiaofei Yu,Xiaojing Yang,Zunming Lu,Xinghua Zhang
Designing catalysts that simultaneously optimize both hydrogen and oxygen evolution reaction (HER and OER) emerges as a critical materials challenge. Co(OH)₂ is recognized as an effective OER electrocatalyst, but the low HER activity limits its application in overall water splitting. In this work, we synthesized sulfur (S) and selenium (Se) doped Co(OH) 2 catalysts with significantly enhanced HER activity using an electrochemical deposition method. The S-Co(OH) 2 and Se-Co(OH) 2 catalysts own low HER overpotentials of 48 mV and 59 mV at 10 mA cm −2 . And they require 1.56 V and 1.64 V at the same current density for water splitting, the sustain stable performance for > 100 h at current densities (100 mA cm −2 ) show their practical durability. Density Functional Theory (DFT) calculations and experimental results reveal that non-metal doping induces electronic reconfiguration of Co and optimizes the ΔG H* value for intermediate formation, thus accelerating hydrogen generation and enhancing the intrinsic HER activity. This work presents an effective strategy for incorporating non-metal elements into transition metal-based catalysts, and provides insight to boost HER intrinsic activity and achieve bifunctional catalytic performance for water splitting.
✓ 已验证
产品关联
DOI
高影响因子
Biomaterials Advances
·
2025
·
IF 6
Long Yang,Yufei Liu,Yong Yang,Yuhu Zhou,Zihao Zou,Min He,Changlei Yang,Daizhu Yuan,Jieheng Wu,Chuan Ye
Artificial bone substitutes have garnered significant attention within the field of biomaterials, and the use of tissue engineering technology to repair bone defects has emerged as a promising alternative. However, when artificial bone substitutes are implanted in the body, they can induce many adverse cellular and tissue immune responses. In this study, we use coaxial electrospinning technology to fabricate microfiber with controllable diameter, excellent mechanical properties and surface porous structure. Poly(3-hydroxybutyrate- co -4-hydroxybutyrate) (P34HB) and polyethylene glycol (PEG) were used as shell solutions and polyvinyl alcohol (PVA) and bone morphogenetic protein-2 (BMP-2) peptides as core solutions. Compared to PVA/P34HB-PEG (P/P-P) scaffolds, PVA-BMP-2/P34HB-PEG (P-B/P-P) scaffolds polarized more human monocytic leukemia cell line (THP-1 cells) toward alternatively activated macrophages (M2), as demonstrated by increased M2 and decreased classically activated macrophage (M1) phenotypic marker expression in the cells. P-B/P-P microfibers have the potential to regulate the polarization state of macrophages, induce them to differentiate into an M2 phenotype and inhibit the inflammatory response of surrounding tissues. In addition, microfibers with a hollow porous structure facilitate the controlled release of BMP-2 peptides by regulating the fiber diameter, enhancing the differentiation of pre-osteoblastic cell line derived from mouse calvaria (MC3T3-E1) cells in an osteogenic direction and facilitating the repair of bone defects in vivo. This study presents microfibers essential for modulating the osteoimmune microenvironment, facilitating efficient bone regeneration.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
INTERMETALLICS
·
2025
·
IF 4.8
Liangcai Du,Xiaoqing Liu,Qianqian Kong,Lichao Gong,Zhenhua Yao
Understanding the intricate phase transformations and their impact on the mechanical properties holds paramount importance in developing high entropy alloys (HEAs) with ideal properties, yet it remains challenging and underexplored. In this study, a series of novel CrFeMnNi (2-x) Ti x (x = 0, 0.5, 1, and 1.5 at.%) HEAs were meticulously designed based on the established Valence Electron Concentration (VEC) rule, with the VEC values systematically varied as the atomic composition (Ni, Ti) changed. The microstructure, phase transformation behavior, mechanical properties, and strengthening mechanisms were systematically investigated. We found that the HEA powders exhibited phase behavior consistent with the VEC rules. The spark plasma sintered (SPSed) HEA bulk samples exhibited a phase transformation attributed to the precipitation of Cr and Mn within the matrix, resulting in the formation of the σ phase. Quantitative calculation of the strengthening mechanisms revealed that grain boundary strengthening and precipitation strengthening were the primary contributors to the high strength of the HEA bulk samples. These findings not only advance the utilization of the VEC rules in HEA material design but also contribute to the understanding of the phase behavior and mechanical properties of HEAs, facilitating the design of high performance HEAs.
✓ 已验证
产品关联
DOI
高影响因子
Frontiers in Bioengineering and Biotechnology
·
2025
·
IF 4.8
Fei Jiang,Zhiming Dong,Xiaoli Lou,Zhuonan Zhang,Li Shuai,Chengke Zhao
Secondary benzyl alcohols (α-OH) in lignin β-O-4 linkages are reactive sites that can trigger undesirable condensation reactions during lignin valorization processes. The selective oxidation of α-OH groups can effectively inhibit lignin condensation reactions, thereby promoting lignin depolymerization. Meanwhile, this approach increases the functionalities, which is beneficial for the design of lignin-derived functional materials. In this study, we report a chemoselective oxidation method using 2-iodoxybenzoic acid (IBX) to selectively convert α-OH groups into ketones. The reaction proceeds under ambient conditions with green DMSO as the sole solvent. Oxidation of β–O–4 model compound (veratrylglycerol-β-guaiacyl ether, VG) revealed exceptional selectivity of this oxidation process, achieving 92% substrate conversion with 90% yield of the corresponding α-ketone product after 48 h. When applied to cellulolytic enzyme lignin, this protocol significantly increased the α-ketone content from 1.2% to 20.5% (relative to total interunit linkages), as identified and quantified by 2D HSQC NMR. The straightforward α-OH oxidation protocol demonstrates significant potential for precise lignin structure modification and rational design of lignin-derived functional materials in sustainable polymer systems.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
LANGMUIR
·
2024
·
IF 3.7
Xue Chen,Yong Xiang,Xiaojing Zhang,Guanlin Li,Sihan Ai,Daoyong Yu,Baosheng Ge
Carbonic anhydrase (CA) plays a crucial role in the CO2 capture processes by catalyzing the hydration of CO2. In this study, we synthesized a bioinspired carbonic anhydrase Zn-MOF (metal–organic framework) incorporating 2-aminoimidazole and Zn2+ as initial constituents. The synthesized Zn-MOF exhibited promising potential for efficiently catalyzing the CO2 hydration. Structural analyses such as SEM, XRD, and BET confirmed that the Zn-MOF crystal consisted of stacked grains with an average size of approximately 36 nm, forming a micron-sized spherical structure. Functionally, Zn-MOF exhibited effective catalytic activity toward both CO2 hydration and ester hydrolysis. The introduction of amino groups significantly enhanced the esterase activity of Zn-MOF to 0.28 U/mg at ambient temperature, which was twice that of ZIF-8. Furthermore, the introduction of amino groups resulted in remarkable hydrothermal stability, with the esterase activity reaching 0.72 U/mg after undergoing hydrothermal treatment at 80 °C for 12 h. Additionally, Zn-MOF exhibited enhanced capability in CO2 hydration at a pH value exceeding 8.5. After six repeated uses, ZIF-8 and Zn-MOF retained approximately 68 and 65% of their initial enzyme activity, respectively, underscoring the potential practical applicability of Zn-MOF in industrial CO2 capture processes. This work showcases the development of a novel Zn-MOF crystal as an efficient CA mimic, effectively emulating the active sites of natural CA using 2-aminoimidazole as a coordinating ligand for Zn2+ coordination. These findings not only advance the field of innovative enzyme mimics but also pave the way for further exploration of industrial CO2 capture catalysts.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
TALANTA
·
2024
·
IF 5.6
Jing-bo Jiao,Qing Kang,Shu-xin Cui,Jiang-li Cao,Tong Lin,Chen-jing Ma,Ze-hui Xiao,Ting Du,Nan Wang,Xin-jun Du,Shuo Wang
Coronavirus disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused secondary pandemic, which still poses a serious threat to physical health and economic development. Herein, the target-driven functionalized DNA hydrogel capillary sensor based on cascade signal amplification and carbon coated cobalt manganese modified by prussian blue and platinum nanoparticles (MnCo@C-Pt-PB NPs) has been successfully developed for dual-mode detection of SARS-CoV-2. The cascade signal amplification triggered by target RNA causes the permeability of the DNA hydrogel loaded in the capillary to be destroyed, thereby releasing the embedded MnCo@C-Pt-PB NPs as signal molecules into 3,3′,5,5′-tetramethylbenzidine/hydrogen peroxide (TMB/H 2 O 2 ) solution under the driving of capillarity. The colorless TMB is then catalyzed to blue oxidation products (oxTMB) due to peroxidase-like activity of MnCo@C-Pt-PB NPs, and MnCo@C-Pt-PB NPs and oxTMB with photothermal properties synergistically increase the system temperature under near-infrared irradiation, which are recorded by portable devices to achieve dual-mode detection. Signals intensity are proportional to the logarithm of T-RNA concentration in a wide detection range (100 aM-100 pM), with a detection limit of 100 aM. Moreover, the reliability of the developed method in oropharyngeal swabs samples has also been validated. The signal conversion and amplification function of functionalized DNA hydrogel enhances the convenience, sensitivity and versatility of the developed method, which is promising to be applied in environmental safety, molecular diagnostic assays and disease prevention.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
RSC Advances
·
2024
·Vol. 14
·期 17
·12049-12057
·
IF 3.9
Xiaofan Su,Yaqi Lin,Xingyu Hu,Xinzhi Tan,Yao Mai,Minyan Jiang,Ruitao Zhang,Fangjun Huo,Lei Liu,Weidong Tian,Li Xie
A novel sustained chlorine-releasing polydimethylsiloxane/Ca(ClO)2 (PDMS/Ca(ClO)2) material was fabricated by encapsulating Ca(ClO)2 in a PDMS matrix due to its high hydrophobicity and high chemical stability, which showed immediate-responsive and long-lasting antibacterial capabilities in aqueous conditions. Free chlorine could be released from the PDMS/Ca(ClO)2 after immersion in water for 2 min and could also be sustainedly released for 2 weeks, while the released concentration is negatively related to the duration time and positively with the initial Ca(ClO)2 contents. Additionally, Ca(ClO)2 powder as a filler significantly affects the crosslinking and pore size of PDMS. The PDMS/Ca(ClO)2 materials exhibited enduring antibacterial performance against Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) in both planktonic and multispecies-biofilm status. It is expected that this PDMS/Ca(ClO)2 material and its similar composite would be promising candidates for wide sustainable disinfection applications in biomedical and industrial fields.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
PHYTOMEDICINE
·
2024
·
IF 6.7
Huijian Chen,Pengxin Liu,Ruitao Yu,Nabijan Mohammadtursun,Ainiwaer Aikemu,Xinzhou Yang
Background and purpose Swertiamarin (STM), a secoiridoid glycoside from Swertia chirayita (Roxb.) H. Karst , has been shown to decrease body weight, blood glucose, and blood lipids by inhibiting adipose tissue hypertrophy. However, the underlying mechanisms remain unclear. In particular, adipose thermogenesis is a novel avenue for exploring the pharmacological effects of STM. We aim to investigate the efficacy of STM on type 2 diabetes mellitus (T2DM), with a focus on underlying mechanisms, particularly the activation of ADRB3/UCP1 thermogenic signaling pathways. Methods T2DM model was established by a high-fat diet (HFD) and streptozotocin (STZ) in C57BL/6 J male mice. Mice were given to either 100 or 200 mg kg -1 /day of STM, or 200 mg kg -1 /day of metformin (Glucophage) via intragastric administration for 7 weeks. In vitro, 3T3-L1 cells were differentiated into adipocytes. Molecular markers related to ADRB3-UCP1 signals, lipolysis, and mitochondrial function were detected. Results STM-treated diabetic mice showed a reduction of body weight, fat mass, and blood glucose/lipids and an improvement in insulin sensitivity. Bioinformatics analysis indicated STM promoted lipid metabolism and mitochondrial function, features by closely associated with adipose thermogenesis. STM upregulated the lipolysis-related genes and p-HSL protein in inguinal subcutaneous white adipose tissue (igSWAT) and brown adipose tissue (BAT). STM-treated mice processed a more active energy metabolism. Additionally, the ADRB3-UCP1 signals, mitochondrial-related genes, and oxidative phosphorylation were improved in igSWAT and BAT. In vitro , we found STM interacted with ADRB3, increasing glucose uptake, glycerol release, ADRB3-UCP1 signals, p-HSL expression, mitochondrial content, oxidative phosphorylation complex expression with improved mitochondrial Δ ψ m, as well as reduced lipid accumulation in adipocytes. All these effects were reversed upon ADRB3 inhibition. Conclusion This study identifies a previously unknown role of STM activating ADRB3/UCP1 signals in adipose tissue, suggesting a potential strategy for treating T2DM.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Environmental Chemical Engineering
·
2024
·
IF 7.4
Xiaocong Yu,Jiahui Kan,Jian Han,Kaili Liu,Jihui Li,Huixin Zhang,Jianxin Chen
With the growing public concern for environmental preservation, this work employs environmentally friendly polyaspartic acid (PASP) as the main chain, to develop a green and efficient dual-function inhibitor with scale and corrosion inhibition . The new inhibitor PASP-2-A was synthesized by grafting 2-amino-benzimidazole (2-A) containing nitrogen heterocyclic into polysuccinimide under alkaline conditions. The corrosion inhibition of carbon steel and brass was determined by static test, polarization curve and electrochemical impedance spectroscopy (EIS). It can be found that PASP-2-A had better scale inhibition performance than PASP under different conditions. The addition of 5 mg·L −1 PASP-2-A can almost 100% prevent the formation of CaCO 3 scale. Molecular dynamics simulation results showed that PASP-2-A significantly destroys the crystal structure of CaCO 3 scale due to the coordination between PASP-2-A and Ca 2+ groups. The modified PASP scale inhibitor can prevent the growth of calcite (110) and (104) crystal faces, regulate the transformation of CaCO 3 from stable calcite to more soluble spherical vaterite , making it less deposit. The electrochemical test results showed that the corrosion inhibition of PASP-2-A is greatly improved compared with PASP, and the corrosion inhibition of Q235 carbon steel increased about 40% at the dosage of 200 ppm. The corrosion inhibition efficiency of H62 brass in 3.5 wt% NaCl was 97.97% with 300 ppm PASP-2-A. Notably, due to its degradable nature, low toxicity, and affordability, PASP-2-A serves as an excellent inhibitor, exhibiting remarkable performance in both scale inhibition and corrosion inhibition. Consequently, it presents a promising avenue for further advancements in modified PASP.
✓ 已验证
产品关联
DOI
高影响因子
APPLIED SURFACE SCIENCE
·
2025
·
IF 6.9
Lang Wu,Zhineng Zhou,Qiaogang Song,Na Yu,Xinghuan Hu,Ying Zhang,Xu Su,Xintong Zhao,Shurong Wang
SnO 2 has attracted significant attention as a potential replacement for TiO 2 in perovskite solar cells (PSCs) due to its high optical transmittance, stable physicochemical properties, and ability to process at low temperatures. However, when an SnO 2 electron-transport layer is prepared using solution gel spin coating, many oxygen vacancy defects are generated in the SnO 2 bulk and on its surface. These defects may result in nonradiative recombination at the SnO 2 /perovskite interface. This study proposes a novel and effective multibottom interfacial modification strategy that introduces 1,2-propanediamine hydroiodic acid (1,2-PDADI) molecules with multiple functional groups at the SnO 2 /perovskite interface. The incorporation of 1,2-PDADI molecules effectively passivates the oxygen vacancy defects at the SnO 2 surface and considerably improves the electronic properties of SnO 2 by reducing nonradiative recombination. Additionally, the interaction between the –NH 3 group in 1,2-PDADI and PbI 2 substantially reduces the PbI 2 content, thereby inhibiting defects forming in perovskite films. As a result, PSCs modified with 1,2-PDADI achieve a higher efficiency of 24.70% and demonstrate reduced hysteresis characteristics compared to the control (22.86 %). Thus, this study offers a cost-effective, straightforward, and effective approach for realizing high-efficiency PSCs.
✓ 已验证
产品关联
DOI
高影响因子
Nature Communications
·
2024
·Vol. 15
·期 1
·1-23
·
IF 14.7
Luo Yu-Wei,Zhou Jiang-Peng,Ji Hongyu,Xu Doudou,Zheng Anqi,Wang Xin,Dai Zhizheng,Luo Zhicheng,Cao Fang,Wang Xing-Yue,Bai Yunfang,Chen Di,Chen Yueming,Wang Qi,Yang Yaying,Zhang Xinghai,Chiu Sandra,Peng Xiaozhong,Huang Ai-Long,Tang Kai-Fu
Though RNAi and RNA-splicing machineries are involved in regulating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) replication, their precise roles in coronavirus disease 2019 (COVID-19) pathogenesis remain unclear. Herein, we show that decreased RNAi component (Dicer and XPO5) and splicing factor (SRSF3 and hnRNPA3) expression correlate with increased COVID-19 severity. SARS-CoV-2 N protein induces the autophagic degradation of Dicer, XPO5, SRSF3, and hnRNPA3, inhibiting miRNA biogenesis and RNA splicing and triggering DNA damage, proteotoxic stress, and pneumonia. Dicer, XPO5, SRSF3, and hnRNPA3 knockdown increases, while their overexpression decreases, N protein-induced pneumonia’s severity. Older mice show lower expression of Dicer, XPO5, SRSF3, and hnRNPA3 in their lung tissues and exhibit more severe N protein-induced pneumonia than younger mice. PJ34, a poly(ADP-ribose) polymerase inhibitor, or anastrozole, an aromatase inhibitor, ameliorates N protein- or SARS-CoV-2-induced pneumonia by restoring Dicer, XPO5, SRSF3, and hnRNPA3 expression. These findings will aid in developing improved treatments for SARS-CoV-2-associated pneumonia.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）