PHYSICA B-CONDENSED MATTER
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2022
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IF 2.988
Xiaohong Pei,Shipeng Yang,Xinfeng Zhu,Erjian Sun,Xiaohan Hei,Zhongxian Song,Kai Liu
Development of multi-colour emitting phosphors for applications in LED is always a hot topic in rencent years. Herein, we prepared solid solutions K 2 Y 1- x - y Tb x Eu y Zr(PO 4 ) 3 and studied their luminescent properties. Both Tb 3+ and Eu 3+ emission peaks can be generated by using characteristic exciting wavelength of Tb 3+ (378 nm) due to the Tb 3+ →Eu 3+ energy transfer. By simply changing the relative proportions of Tb 3+ /Eu 3+ , the emitting color of phosphors K 2 Tb 1- y Eu y Zr(PO 4 ) 3 changes from green ( y = 0), through yellow ( y = 0.005) to red ( y = 0.08). Thermostability study showed that at 150 °C, the integral intensity is 57% of that at 25 °C, suggesting a good thermostability. Finally, we fabricated three LED lamps by using a 365 nm chip with y = 0, 0.005, 0.08 phosphors, and green, yellow and red light can be observed.
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Food Quality and Safety
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2022
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IF 3.949
Cai Chenggang,Chang Guoli,Zhang Nianhua,Wang Junlin,Wang Liyuan,Wu Pinggu,Yang Dajin
ObjectivesPolycyclic aromatic hydrocarbons (PAHs) and 3-monochloropropane-1,2-diol ester (3-MCPDE) were studied in camellia oil. It is important to study the changes in the content of PAHs and 3-MCPDE at different refining stages (from crude oil to the final refined oil product) to elucidate the influence of the refining procedures on their change.Materials and methodsThe PAHs and 3-MCPDE in camellia oil from different refining stages (from crude oil to the product) of a plant were analyzed by gas chromatography–mass spectrometry and calculated by the internal standard method.ResultsThe overall PAH content was (79.64±2.43) µg/kg in crude camellia oil. After refining treatment, the PAH content decreased to (18.75±0.55) µg/kg. The 3-MCPDE content increased during the refining process from 0 mg/kg in the crude oil to 4.62 mg/kg in the refined oil product.ConclusionsThis is the first study to simultaneously monitor changes in both PAH and 3-MCPDE contents during the production of camellia oil. These results confirmed the effectiveness of the refining method on PAH removal and the increase in 3-MCPDE at high temperature. It is suggested that novel processing methods or refining parameters need further optimization to decrease the overall concentrations of PAHs and 3-MCPDE in camellia oil.
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Frontiers in Aging Neuroscience
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2022
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IF 5.702
Wang Wang,Guoxue Zhu,Yuwen Wang,Wei Li,Shilin Yi,Kai Wang,Lu Fan,Juanjuan Tang,Ruini Chen
Background Parkinson’s disease (PD) is a multifactorial degenerative disease of the central nervous system, which affects mostly older adults. To date, research has focused on the progression of PD. Simultaneously, it was confirmed that the imbalances in gut microbiota are associated with the onset and progression of PD. Accurate diagnosis and precise treatment of PD are currently deficient due to the absence of effective biomarkers. Methods In this study, the pharmacodynamic study of cyanidin-3- O -glucoside in PD mice was used. It intends to use the “imbalance” and “balance” of intestinal microecology as the starting point to investigate the “gut-to-brain” hypothesis using metabolomic-combined 16S rRNA gene sequencing methods. Simultaneously, metabolomic analysis was implemented to acquire differential metabolites, and microbiome analysis was performed to analyze the composition and filter the remarkably altered gut microbiota at the phylum/genera level. Afterward, metabolic pathway and functional prediction analysis of the screened differential metabolites and gut microbiota were applied using the MetaboAnalyst database. In addition, Pearson’s correlation analysis was used for the differential metabolites and gut microbiota. We found that cyanidin-3- O -glucoside could protect 1-methyl-4-phenyl-1,2,3,6− tetrahydropy ridine (MPTP)-induced PD mice. Results Metabolomic analysis showed that MPTP-induced dysbiosis of the gut microbiota significantly altered sixty-seven metabolites. The present studies have also shown that MPTP-induced PD is related to lipid metabolism, amino acid metabolism, and so on. The 16S rRNA sequencing analysis indicated that 5 phyla and 22 genera were significantly altered. Furthermore, the differential gut microbiota was interrelated with amino acid metabolism, and so on. The metabolites and gut microbiota network diagram revealed significant correlations between 11 genera and 8 differential metabolites. Conclusion In combination, this study offers potential molecular biomarkers that should be validated for future translation into clinical applications for more accurately diagnosing PD. Simultaneously, the results of this study lay a basis for further study of the association between host metabolisms, gut microbiota, and PD.
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PubMed
高影响因子
FOOD CHEMISTRY
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2022
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IF 9.231
Hongdong Song,Qingyu Wang,Aijing He,Sen Li,Xiao Guan,Yawen Hu,Siyi Feng
Hordein nanoparticles have been successfully fabricated to encapsulate EGCG. The present study aimed to investigate the effect of hordein nanoparticles encapsulation on antioxidant activity, storage stability and in vitro release of EGCG. The antioxidant activities of EGCG before and after encapsulation by hordein nanoparticles had no significant difference. The 28-day storage experiments indicated that EGCG-hordein nanoparticles had a good storage stability in terms of average diameter and zeta potential. Meanwhile, the stability of EGCG was significantly improved by hordein nanoparticles encapsulation. The remaining amount of encapsulated EGCG was 1.31-fold and 1.52-fold higher than that of free EGCG at 4 °C and 25 °C, respectively. The release study in the simulated gastric or intestinal fluids suggested that hordein nanoparticles could slow down the release of EGCG in the simulated gastric or intestinal fluids. These results showed that encapsulation of EGCG using hordein nanoparticles could be a promising approach to improve its stability.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
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IF 5.518
Yan Yi,Xiangyu Wang,Yaxian Zhang,Jun Ma,Ping Ning
The aquatic plant Egeria najas based biochar was innovatively constructed by modifying it with Fe 2 (SO 4 ) 3 (Fe 2 (SO 4 ) 3 @EN-BC) for Cr(VI) removal. The characterizations of Fe 2 (SO 4 ) 3 @EN-BC confirmed that Fe 2 (SO 4 ) 3 was attached to biochar in form of Fe 2 O 3 after hydrolysis and calcination under high temperature. The results showed that Fe 2 (SO 4 ) 3 @EN-BC had a high removal efficiency of Cr(VI) with approaching 99.88%, which was about 7 times higher compared to unmodified biochar (EN-BC). Batch experiments of Cr(VI) removal included initial concentration, reaction temperature, solution pH and kinetics were conducted. The adsorption kinetics could be more accurately explained using pseudo-second order kinetics model , indicating the chemical adsorption controlled the reaction process. According to the Langmuir model, the maximum adsorption capacities for Cr(VI) were 138.79, 159.36 and 190.91 mg/g at 298, 313 and 333 K, respectively. Moreover, based on FTIR and XPS results, the Fe 2 (SO 4 ) 3 @EN-BC surface was loaded with many functional groups conducive to Cr(VI) adsorption. The main removal mechanisms of Cr(VI) by Fe 2 (SO 4 ) 3 @EN-BC included adsorption and reduction, and the percentage of Cr(VI) removed by adsorption and reduction were 19.1% and 80.9%, respectively.
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CATALYSIS TODAY
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2022
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IF 6.562
Yiming Ma,Yushuai Sang,Kai Wu,Qingfeng Liu,Hong Chen,Yongdan Li
Low selectivity and complex product distribution are the main challenges for the utilization of lignin. Herein, the selective production of 2-(tert-butyl)-3-methylphenol (TBC), an antioxidant in the polymer industry, from depolymerization of enzymatic hydrolysis lignin (EHL) on a hydrothermally synthesized MoS 2 catalyst is studied. The total aromatic monomer yield is 124.1 mg/g EHL and the selectivity of TBC is up to 40.3 wt% in methanol at 280 °C under 2 MPa H 2 for 6 h. The FT-IR analysis of products reveals that MoS 2 has a high activity for demethylation, dehydroxylation and alkylation, and the dimer conversions reveal that C-O and C-C bonds in EHL are broken with MoS 2 . The guaiacol and its derivants are identified as the intermediate for formation of TBC in EHL depolymerization according to the effect of time on product distribution and monomer conversion.
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COLLOIDS AND SURFACES B-BIOINTERFACES
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2022
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IF 5.999
Shuaishuai Yuan,Xiuxia Sun,Shunjie Yan,Shifang Luan,Lingjie Song,Jinghua Yin
Vaseline gauze is a common type of wound dressing that consist of absorbent gauze impregnated with white petrolatum. It has excellent anti-adhesive property which can reduce trauma during dressing changes. However, this kind of wound dressing doesn’t have bacterial killing property. Thus, a new kind of wound dressing that has anti-adhesive and bactericidal properties is needed urgently. Creating slippery liquid-impregnated porous surfaces (SLIPS) that insensitive to the structure of porous solid are generally viewed as a new anti-adhesion strategy. To expand the potential utility of SLIPS as substitute for vaseline gauze, dual-functional slippery membranes with anti-adhesion and bactericidal properties by using triclosan , vegetable oils and polylactic acid (PLA) were prepared. It’s demonstrated that the triclosan-loaded/vegetable oils-infused PLA membranes (T/V-PM) has good cytocompatibility in vitro . Notably, the T/V-PM can gradually release biocide molecule into surrounding aqueous media. Moreover, the T/V-PM can kill planktonic bacterial cells without loss of their antifouling property. The in vivo study revealed that the T/V-PM can prevent the secondary injuries during wound dressing changes. This simple and low-cost strategy can be applied to inhibit blood and bacterial adhesion , and prevent tissue adhesion at the wound site. It’s confirmed that the T/V-PM have great potential as substitute for vaseline gauze.
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CARBOHYDRATE POLYMERS
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2021
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IF 9.381
Xianglin Pan,Haoyu Wang,Ziming Zheng,Xiao Huang,Linlin Yang,Junxi Liu,Kaiping Wang,Yu Zhang
Ulcerative colitis (UC) is an inflammatory bowel disease that affects the colon and rectum. Although galectin-3 (Gal-3) has been reported to play a proinflammatory role in UC, it is unknown whether pectic polysaccharide , a Gal-3 inhibitor in tumor metastasis, can alleviate UC by inhibiting Gal-3. The aim of this study was to investigate the anti-inflammatory effects and underlying mechanisms of SCLP, a pectic polysaccharide purified from Smilax china L. in our previous work, on dextran sulfate sodium-induced UC in BALB/c mice. The results showed that SCLP could significantly improve symptoms, alleviate histopathological damage and reduce the secretion of inflammatory mediators in mice with UC. Analysis of the anti-colitis mechanisms indicated that SCLP could inhibit the Gal-3/NLRP3 inflammasome/IL-1β pathway by suppressing the expression of Gal-3 and the interaction of Gal-3 and NLRP3 . Our results suggested that SCLP could be a promising candidate for prevention and treatment of UC.
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Journal of Stroke & Cerebrovascular Diseases
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2021
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IF 2.136
Chaoqun Lin,Shiying Huang,Jianfeng Zhang,Huaitao Yuan,Tuchao Yao,Lukui Chen
Objective To assess the potential effect of dl-3-N-butylphthalide (dl-NBP) for the proliferation and differentiation of neural stem cells (NSCs) against hypoxia and the underlying mechanism. Materials and methods Hippocampal NSCs were obtained from fetal rats. NSCs combined with dl-NBP and single NSCs were cultured. The impact of siRNA-mediated hypoxia-inducible factor-1alpha (HIF-1α) knockdown on NSCs was detected with western blotting (WB) and quantitative real-time reverse transcription polymerase chain reaction (RT-qPCR). Cell-counting kit-8 assay was used for evaluating the viability of NSCs. Levels of HIF-1α protein were measured using WB, and vascular endothelial growth factor (VEGF) expression was quantified using RT-qPCR and enzyme-linked immunosorbent assay. Results Compared with 7 different concentrations of dl-NBP, 0.25 g/L was determined as the optimal concentration to significantly increase the viability of NSCs (p < 0.001). Dl-NBP can significantly increase the viability of hypoxic NSCs ( p < 0.001) and improve the differentiation of hypoxic NSCs into astrocytes ( p = 0.001) and oligodendrocytes ( p < 0.001). Meanwhile, Dl-NBP can significantly elevate levels of HIF-1α protein ( p < 0.001) and VEGF mRNA ( p = 0.001) / protein ( p < 0.001) in NSCs in the hypoxic environment. However, after transfection with HIF-1α siRNA in NSCs, the viability and differentiation of NSCs was not recovered using dl-NBP under the hypoxic condition, as well as levels of HIF-1α and VEGF. Conclusion Dl-NBP can reverse the weaker proliferation and differentiation power of NSCs in the hypoxic environment. The HIF-1α - VEGF pathway may be implicated in this protective effect of dl-NBP.
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JOURNAL OF MEMBRANE SCIENCE
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2023
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IF 9.5
Zewen Xu,Zhongyi Ren,Haojiang Zhu,Hao Guo,Xinliang Liu,Ming Wang,Yingfei Hou
Layer-by-layer (LBL) assembly method, with the advantages of simple operation and strong universality, has attracted much attention recently. However, the weak molecule-to-molecule and molecule-to-ion interactions have limited its development. During this work, the molecule-to-solid interaction was adopted and a robust LBL coating was achieved by alternately depositing positively charged Fe(OH) 3 colloids and negatively charged sodium alginate molecules. The molecule-to-solid interaction could continuously regenerate under corrosive conditions due to water insolubility and the chemical stability of solids. When the electrostatic interaction was broken, the abundant chemically stable solids acted as anchors to immobilize the soluble molecules and maintain the stability of the LBL coating. The prepared superwettable membranes exhibited superior oil-in-water emulsion separation efficiency, anti-fouling properties, and chemical stability. Meanwhile, the separation performance survived one week's harsh environments of strong acid and alkali.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2023
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IF 9.9
Shaoxiong Liu,Xiao Li,Siwei Zhong,Wenjia Jiang,Ye Liu,Wenchong Ding,Hai Hu,Zhifeng Huang,Li Liu
NASICON-structured Ti-based polyanion compounds benefit from a stable structural framework, large ion channels, and fast ion mobility . However, the large radius of potassium and its poor electronic conductivity restrict its use in potassium-ion batteries. Herein, hierarchical mesoporous Mn 0.5 Ti 2 (PO 4 ) 3 @C microspheres have been successfully synthesized using a simple electrospraying method. These microspheres consist of Mn 0.5 Ti 2 (PO 4 ) 3 nanoparticles evenly embedded in three-dimensional mesoporous carbon microspheres. The hierarchical mesoporous micro/nanostructure facilitates the rapid insertion and extraction of K + , while the three-dimensional carbon microspheres matrix enhances electrical conductivity and prevents active materials from collapsing during cycling. So the hierarchical mesoporous Mn 0.5 Ti 2 (PO 4 ) 3 @C microspheres exhibit a high reversible discharge specific capacity (306 mA h g −1 at 20 mA g −1 ), a notable rate capability (123 mA h g −1 at 5000 mA g −1 ), and exceptional cycle performance (148 mA h g −1 at 500 mA g −1 after 1000 cycles). The results show that electrosprayed Mn 0.5 Ti 2 (PO 4 ) 3 @C microspheres are a promising anode for PIBs.
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ANTI-CANCER DRUGS
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2023
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IF 2.3
Wang Guangxin,Gao Xia,Sun Zhijun,He Tianyou,Huang Chaogang,Li Shouwei,Long Haocheng
Enhancing research indicatedthat circular RNA (circRNA) acted a critical part in cholangiocarcinoma (CHOL) development. This research aims to discover the role of circRNA SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily a, member 5 ( SMARCA5 ) in CHOL bio-progression, which has been proved to be downregulated in CHOL tissues. In this study, quantitative reverse transcription polymerase chain reaction was used to reveal the level and linkage of circRNA SMARCA5 , miRNA-95-3p and TNF receptor-associated factor 3 gene ( TRAF3 ) in CHOL tissues and cancer cells. The target sites of circRNA SMARCA5 and miRNA-95-3p were forecast by Starbase, and Targetscan was conducted to forecast the potential linkage points of TRAF3 and miRNA-95-3p , and which is affirmed by double luciferase reporter assay. CCK-8 and flow cytometry assay was carried to indicate cell viability. And apoptosis-related protein was counted by caspase3 activity and Western blot assay. CircRNA SMARCA5 was downregulated in CHOL cell lines and cancer samples. Besides, over-expression of SMARCA5 inhibited cell growth and promoted apoptotic rate. Dual-luciferase reporter assays presented that miRNA-95-3p could link with circRNA SMARCA5 . Moreover, miRNA-95-3p was discovered highly expressed in CHOL. Interference of miRNA-95-3p repressed cell proliferation and raised the apoptosis. Importantly, TRAF3 was validated to be a downstream of miRNA-95-3p . Strengthen of miRNA-95-3p reversed the inhibitory impact of circRNA SMARCA5 -plasmid transfection, and the results of miRNA-95-3p inhibitor were reversed by si- TRAF3 . CircRNA SMARCA5 is involved in CHOL development by interosculating miRNA-95-3p / TRAF3 axis and may become a novel approach for treating CHOL.
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