LWT-FOOD SCIENCE AND TECHNOLOGY
·
2023
·
IF 6
Zhenfeng Xie,Yi Wu,Xin Lu
In this study, we encapsulated epigallocatechin gallate (EGCG) in emulsified oil droplets of protein-stabilized emulsions for the first time, with the participation of peppermint essential oil (PEO). Gum arabic (GA) and sodium caseinate (SC) were sufficiently crosslinked to construct the oil-water interface of the emulsion, improving the stability of EGCG in the emulsified oil droplets. When SC and 4 g/kg GA were mixed for 12 h before emulsification, the protein adsorption at the oil-water interface was significantly enhanced. Compared with the SC-stabilized emulsion, the retention of EGCG in the emulsion stabilized by mixing SC and 4 g/kg GA for 12 h increased about 2 and 33 times, respectively, after thermal treatment (30 min at 90 °C) and storage 10 weeks at 4 °C. Moreover, the emulsion stabilized by SC and 4 g/kg GA was resistant to the ionic strength of 0–0.6 mol/L and had predominantly elastic characteristics in the rheological properties. This indicates that the stability of active ingredients in emulsified oil droplets can be improved by regulating the rheological properties of the oil-in-water emulsion. The study is of great value for the efficient encapsulation and stability improvement of hydrophilic active ingredients in emulsified oil droplets based on emulsion systems.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2022
·
IF 9.965
Yunfeng Qiu,Xiaofan Dai,Yanping Wang,Xinyang Ji,Zhuo Ma,Shaoqin Liu
It is urgent to develop non-noble metal electrocatalysts with both excellent activity and durable stability for H 2 production via water electrolysis. Electric energy is mainly consumed by the sluggish anodic oxygen evolution reaction (OER). The electrocatalytic urea oxidation reaction (UOR) has been regarded as a promising reaction to replace OER because of its small thermodynamic oxidation potential . However, developing a facile and large-scale preparation method for bifunctional hydrogen evolution reaction (HER) and UOR electrocatalysts is still challenging. Herein, phosphate-modified (4.46 atomic%) NiMoO 4−x net-like nanostructures are formed on Ni foam (NF) via H 3 PMo 12 O 40 etching strategy at room temperature (denoted as NF/P-NiMoO 4−x ). The etched NF can directly serve as HER electrode , and delivers overpotential of 116 mV at current density of 10 mA/cm 2 with Tafel slope of 77.5 mV/dec. Furthermore, it displays excellent UOR activity with potential of 1.359 V at current density of 10 mA/cm 2 and Tafel slope of 19.3 mV/dec. The apparent activation energy of NF/P-NiMoO 4−x is 20.6 kJ/mol, lower than that of NF (37.7 kJ/mol), indicating smaller apparent barrier for C N bond cleavage in urea. The cell voltage of urea electrolysis is around 1.48 V for H 2 production to deliver current density of 10 mA/cm 2 , and better long-term stability for 50 h than that of Ir/C||Pt/C. The etching solution can be recycled for five times by addition of H 2 O 2 , turning heteropoly blue into its original state. This work develops a facile and large-scale method to prepare bifunctional HER and UOR electrocatalysts for H 2 production in a less-energy saving way via urea electrolysis.
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INTERNATIONAL DAIRY JOURNAL
·
2022
·
IF 3.572
Xianglin Yue,Junru Sun,Ru Zhao,Jinsheng Zhang
Rapid screening and early warning of pathogenic bacteria in food is the key to prevent and control the spread of foodborne diseases . Biotin–streptavidin system and membrane filtration technology were combined to develop a novel nuclear magnetic resonance (NMR) immunosensor based on biomacromolecule O-carboxymethyl chitosan (O-CMCS) target gadolinium (Gd) probe for rapid detection of Salmonella anatum in milk. Under optimal experimental parameters, the proposed NMR immunosensor could detect Salmonella in milk with a limit of detection of 1.8 × 10 4 cfu mL −1 within 2 h. Furthermore, the immunosensor exhibited good specificity, sensitivity and reproducibility, which could achieve the direct determination of biological samples with complex composition. Hence, the developed assay might have great application potential for the rapid detection of Salmonella in food.
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JOURNAL OF FOOD SCIENCE
·
2022
·Vol. 87
·期 5
·2159-2172
·
IF 3.693
Zhenzhu Zhu,Lipin Yang,Zhong Li,Qin Liu
Neurotoxicity seriously affects the normal function of the nervous system. Cyanidin-3-O-glucoside (C3G) is the most abundant anthocyanin widely distributed in plants. Using β -amyloid (A β ) transgenic Caenorhabditis elegans and cell models, the neuroprotective effect of C3G was examined. The results showed that C3G remarkably suppressed A β aggregation, enhanced antioxidant capacity, improved the sensitive capacity towards chemical compounds, and boosted the memory ability of C. elegans . There was no significant difference between preventive and long-term treatment groups at the same dosage of C3G. Given the rapid metabolism and oxidation of C3G in vivo, the antioxidative and anti-inflammatory activities of C3G, the metabolite cyanidin (Cy), oxidation products of Cy (OP), as well as protocatechuic acid (PCA) at the corresponding level in OP were compared by using lipopolysaccharide (LPS)-stimulated BV2 microglia cell model. The results indicated that C3G, Cy, and OP could prevent BV2 cells against LPS-induced inflammation and oxidative damage. There was no significant difference on antioxidative and anti-inflammatory activities among C3G, Cy, and OP at the same level. Notably, PCA at the corresponding concentration in OP exhibited limited antioxidative and anti-inflammatory activities. The results suggested that C3G could exert neuroprotective function through the metabolite Cy and its oxidation products by inhibiting inflammation and oxidative damage, and PCA was not the primary bioactive species in OP. Practical Application This study confirmed the neuroprotection of cyanidin-3-O-glucoside (C3G) in transgenic Caenorhabditis elegans . C3G, its metabolite cyanidin (Cy), and oxidation products of Cy (OP) alleviated both neuroinflammation and oxidative damage. It highlighted that C3G-rich foods could exert neuroprotective potential through their oxidation products, the constitution, and existence of OP in vivo need further study.
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CARBOHYDRATE POLYMERS
·
2021
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IF 9.381
Yuerong Yang,Yu Lu,Yinchuan Liu,Yu Pan,Hongjuan Ma,Linjuan Huang,Zhongfu Wang
Yak milk (YM) has higher protein content than other bovine milk (BM) varieties. The bioactivity of milk glycoproteins is related to N / O -glycans. We qualitatively and quantitatively compared the N / O -glycome of YM and BM glycoproteins using stable isotope labeling combined with hydrophilic interaction chromatography and electrospray ionization mass spectrometry. We identified 79 and 78 N -glycans in YM and BM, respectively. Two N -glycans (H4N5F1A1; H5N4F1) were exclusive to YM. The content ratios of different types of N -glycans differed significantly between YM and BM, with sialylated N -glycans 2.33 times more abundant in YM. Five and seven O -glycans were detected in YM and BM, respectively. Two O -glycans (H1N2; H1N2A1) were exclusive to BM. The bi-sialylated O -glycan, H1N1A2, accounted for 56.1% of O -glycans in YM; it was 5.97 times more abundant in YM than in BM (equal volume basis). This study provides a theoretical basis for the future utilization of YM as a functional food.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2021
·
IF 5.279
Yujiao Cheng,Guijie Li,Houjiu Wu,Linhua Huang,Hua Wang
Light-induced off-flavor compounds in Ponkan mandarin juice were investigated during its shelf-life by headspace solid-phase microextraction multidimensional gas chromatography–mass spectrometry/olfactometry (MDGC-MS/O) and a GC–MS/pulsed flame photometric detector (GC–MS/PFPD). A total of 34 aroma-active compounds with flavor dilution (FD) factors from 2 to 128 were tentatively identified by aroma extract dilution analysis-MDGC-MS/O. Among them, a light-induced off-flavor compound with a high FD factor, methional (cooked potato), was positively identified in the Ponkan mandarin juice at the end of the shelf-life. In addition, 11 volatile sulfur compounds (VSCs), including 6 screened shelf-markers (variable identification, VID > 0.80), were identified in Ponkan mandarin juice by a sulfur detector (PFPD). Four VSCs exhibited odor activity values exceeding 1. Three VSCs (methanethiol, dimethyl trisulfide, and methional) were confirmed as key light-induced off-flavor compounds in Ponkan mandarin juice based on addition/omission experiments. Furthermore, light irradiation accelerated the degradation of sulfur precursors (methionine and MMS) and the formation of these VSCs leading to an increase in off-flavor intensity.
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EXPERIMENTAL CELL RESEARCH
·
2023
·
IF 3.7
Hong Liu,Yang Huang,Jing Yang,Xuejiao Xu,Qiaomei Dai,Yuwei Zhang,Li Zhao,Mengdi Zhang,Jing Zhang,Tonghui Liu,Lili Zhong
Estrogens have been demonstrated to inhibit age-related cognitive decline via binding to estrogen receptors (ERs). As a natural flavonoid component of Cuscuta Chinensis Lam. , Kaempferol-3- O -glucoside (K-3-G) not only possesses anti-neuroinflammatory potential but also functions as an agonist for ERα and ERβ. This study aimed to determine whether K-3-G improved cognition during the aging process, with an emphasis on its effect on microglial inflammation. In vivo , K-3-G (5 or 10 mg/kg/day) was orally given to the senescence-accelerated mouse prone 8 (SAMP8) mice from six to eight-month old. In addition to mitigating the memory and learning deficits of SAMP8 mice, K-3-G upregulated the expression of ERα and ERβ in their hippocampal CA1 region, with the higher dose being more effective. Less Iba-1 + microglial cells presented in SAMP8 mice treated with K-3-G. The formation of NLR Family Pyrin Domain Containing 3 (NLRP3) complex, production of pro-inflammatory cytokines and oxidative stress-related markers, as well as expression of pro-apoptotic proteins were reduced by K-3-G. In vitro , BV2 microglial cells exposed to oligomeric amyloid beta (Aβ) 1-42 were treated with 100 μM K-3-G. K-3-G showed similar anti-inflammatory effects on BV2 cells as in vivo . K-3-G-induced alterations were partly diminished by fulvestrant, an ER antagonist. Moreover, dual-luciferase reporter system demonstrated that K-3-G induced ER expression by activating the transcription of estrogen-response elements (EREs). Collectively, these findings demonstrate that K-3-G may be a novel therapeutic agent for senescence-related cognitive impairment by inhibiting microglial inflammation through its action on ERs.
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
·
2015
·
IF 3.447
Feifei Li,Guoli Wu,Huixia Zheng,Li Wang,Zhengbao Zhao
A glycoside prodrug of 4-aminosalicylic acid (4-ASA) with d -glucose was synthesized for targeted drug delivery to inflammatory bowel. The in vitro assessment of 4-aminosalicylic acid-β-O-glucoside (4-ASA-Glu) as a colon-specific prodrug was studied using colitis rat with the healthy one as control. The stability studies in aqueous buffers (pH 1.2, 6.8 and 7.4) indicated that 4-ASA-Glu was stable over a period of 12 h. The incubation of 4-ASA-Glu with cecal or colonic contents of healthy rats at 37 °C released 4-ASA in 77 or 80% of the dose in 12 h, respectively. The amount of 4-ASA liberated from the incubation of 4-ASA-Glu in cecal or colonic contents of colitis rats at 37 °C was 69 or 79% in 12 h respectively, while less than 9% 4-ASA was detected from the incubation of 4-ASA-Glu with the homogenates of stomach or small intestine . The curative effect of 4-ASA-Glu was evaluated in 2, 4, 6-trinitrobenzenesulfonic acid (TNBS) induced experimental colitis model in male Sprague–Dawley (SD) rats. It was found that 4-ASA-Glu possess significantly ameliorate effect than sulfasalazine , oral 4- and 5-aminosalicylic acid.
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DIAMOND AND RELATED MATERIALS
·
2023
·
IF 4.1
Shangshu Peng,Yang Wu,Shengshang Lu,Ruiya Zhao,Linxi Dai,Bo Chen,Quan Xie,Yunjun Ruan
Among the numerous benefits of porous carbon materials, their economic viability, abundance of availability, and environmental sustainability have made them increasingly popular in the realm of energy transformation and storage. Herein, the rotted Cucurbita pepo L. precursor was served as the starting material for the production of nitrogen (N) and oxygen (O) co-doped porous activated carbon, which was involved in high-temperature carbonization and KOH activation processes . The rotted Cucurbita pepo -derived activated carbon (RCPAC) showcases a remarkably elevated specific surface area of 2434 m 2 g −1 , while its micropore volume is 0.73 cm 3 g −1 . These inherent attributes offer a significant quantity of electroactive sites that effectively enable the electrochemical process of adsorption as well as the desorption of electrolyte ions . The RCPAC electrode demonstrates a notable specific capacitance value of 208 F g −1 when subjected to the current density of 1 A g −1 . Furthermore, it retains >99 % of its original capacitance even after undergoing 10,000 cycles at a current density of 10 A g −1 . Moreover, a symmetric supercapacitor (SSC) consisting of RCPAC electrodes and 6 M potassium hydroxide (KOH) electrolyte results in a significant specific capacitance of 55 F g −1 at 0.25 A g −1 . The SSC demonstrates an impressive retention of capacitance, amounting to 85.6 %, even subsequent to enduring a substantial number of 8000 charge/discharge cycles. Additionally, an SSC was assembled using two undifferentiated RCPAC-6 electrodes in [BMIM]BF 4 /AN electrolyte. The SSC exhibits an impressive energy density of 92.25 Wh kg −1 , while simultaneously maintaining a power density of 374.9 Wh kg −1 . Furthermore, it demonstrates a capacitance retention surpassing 72.6 % subsequent to enduring 5000 cycles at 2 A g −1 . Our research elucidates a financially feasible methodology for the fabrication of porous carbon-based compounds, which exhibit immense potential for deployment in various energy conversion and storage .
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Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 6
·125110
·
IF 7.5
Bingdang Wu,Zihao Cang,Yonghai Gan,Jun Luo,Zhe Li,Zheng Wang,Hongcen Zheng,Minghui Cai,Xiao Luo,Chengcheng Ding,Yibin Cui
Synthesis pathway governs Si-O-Fe bonding uniformity and functional group exposure. • GPFC-H unlocks pH-switchable synergy: charge neutralization (acidic) and hydrophobic association (alkaline). • GPFC-H achieves 91.2% HA removal at pH 6.0 and 74% at pH 9.6, versus < 41% for PFC. • The GPFC-H route requires no post-treatment and is compatible with spray drying. • Spray-dried powder retains > 90% coagulation activity after 28-day storage. Long-chain silane coupling agents like dimethyloctadecyl[3-(trimethoxysilyl)propyl]ammonium chloride (TPODAC) promise enhanced coagulation performance through hydrophobic interactions, yet their practical application is crippled by uncontrolled hydrolysis and detrimental self-condensation during conventional synthesis. This study demonstrates that the synthesis pathway fundamentally governs Si-O-Fe bonding configuration, colloidal stability, and the resulting coagulation mechanisms. By systematically comparing four synthesis strategies with modulated silane hydrolysis states and component addition sequences, a clear structure-property hierarchy is established through multi-method characterization (FTIR, XPS, XRD, zeta potential) and coagulation performance evaluation. The optimal route, pre-hydrolyzed silane grafted onto pre-formed polymeric ferric chloride (GPFC-H), suppresses silane self-condensation and yields uniform Si-O-Fe covalent bonding with fully exposed quaternary ammonium and C18 hydrophobic chains. This structural perfection unlocks a rare pH-switchable multi-mechanism synergy. At pH 6.0, GPFC-H achieves 91.2% humic acid removal via charge neutralization. Remarkably, at pH 9.6 where conventional coagulants fail (<41% removal), GPFC-H maintains 74% removal through hydrophobic association mediated by its pH-insensitive C18 chains. GPFC-H also achieves 78% Sb(V) removal at pH 7.0, versus 65% for PFC. Furthermore, this synthesis route requires no post-treatment and is compatible with spray drying; the obtained solid powder retains > 90% of its initial activity after 28-day storage, demonstrating its practical potential for industrial production and long-distance transport. By establishing causal links from synthesis pathway to bonding structure to pH-adaptive performance, this work transforms hybrid coagulant preparation from empirical optimization into a designable strategy for advanced water purification. Download: Download high-res image (173KB) Download: Download full-size image
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FOOD RESEARCH INTERNATIONAL
·
2023
·
IF 8.1
Mingguang Yu,Qinggang Xie,Huanlu Song,Lijin Wang,Han Sun,Shilong Jiang,Yongjiu Zhang,Chengdong Zheng
Odor analysis of human milk (HM) is often challenging. Here, a new strategy for the analysis of odorants in HM using dynamic headspace sampling combined with comprehensive two-dimensional gas chromatography–olfactometry-mass spectrometry (DHS/GC × GC-O-MS) was established based on the comparison of different extraction methods and instrument modes. Overall, DHS/GC × GC-O-MS was proved to be able to provide higher extraction efficiency and better analytical results of the odor-active compounds (OACs) in HM, meanwhile, the salt addition during the extraction further promoted the release of the odorants. Twenty key OACs in HM were identified by flavor dilution analysis and odor activity calculation, of which 1-octen-3-one, 2,3-butanedione, ( E )-2-nonenal, and nonanal contributed significantly to the odor of HM. In addition, 2,3-pentanedione was detected as a key OAC in HM for the first time. This study provided a powerful analytical strategy for the comprehensive odor analysis of HM.
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Chem Catalysis
·
2023
·
IF 9.4
Rong Wang,Yue Peng,Jane Chung,Zhen Chen,Xiyang Wang,Haibo Yin,Yimin A. Wu,Jingshan Luo,Junhua Li
Summary The electrocatalytic reduction of CO 2 is an attractive method for reducing greenhouse gases and producing chemical feedstocks. However, the activation of C=O bonds limits the reaction kinetics; therefore, understanding the mechanism of C=O bond activation can guide the design of high-performance catalysts. Here, we investigate the C=O bond activation mechanism during the electroreduction of CO 2 to CO on ZnO. Using in situ experimental techniques and quantum chemical calculations , we find that defects in ZnO promote the formation of Zn–ZnO x interfaces during CO 2 reduction, which mediates an intimate-junction exciton state by the metal semiconductor heterophase. This promotes the formation of CO 2 radicals, exposing electron donation centers for CO 2 adsorption and redox centers for cleaving stable C=O bonds. The internal electric field generated by the heterojunction enhances the initial C=O activation by facilitating the interaction between the metalized Zn d-orbital and the O π -orbital in CO 2 .
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危险品化学品经营许可证（带存储）