Evidence-based Complementary and Alternative Medicine
·
2020
·
IF 1.813
Yongpan Huang,Xian Long,Xinliang Li,Saihua Li,Jianbin He
Background. Oxymatrine (OMT) is the primary pharmacological component of Sophora flavescens Aiton., which has been shown to possess potent antifibrotic, antioxidant, and anti-inflammatory activities. The aim of the present study was to clarify the protective mechanism of OMT on acute lung injury (ALI) subjected to myocardial ischemia/reperfusion (I/R). Methods. A myocardial I/R-induced ALI model was achieved in diabetic rats by occluding the left anterior descending coronary artery for 1 h, followed by reperfusion for 1 h. The levels of inflammatory factors (tumor necrosis factor-α, interleukin- (IL-) 6, and IL-17) in bronchoalveolar lavage fluid were assessed using commercially available kits. The index of myocardial injury, including the detection of cardiac troponin I (cTnI), cardiac troponin T (cTnT), lactate dehydrogenase (LDH), and creatine kinase-MB (CK-MB), was also determined using commercially available kits. Hematoxylin and eosin staining and terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling were used to identify histological changes. The expression levels of endoplasmic reticulum chaperone BiP (GRP78), DNA damage-inducible transcript 3 protein (CHOP), eukaryotic translation initiation factor 2-alpha kinase 3 (PERK), inositol dependent enzyme 1α (IRE1α), ATF6, caspase-3, -9, and-12, Bcl-2, and Bax were determined by Western blotting. The mRNA expression levels of GRP78 and CHOP were detected by reverse transcription-quantitative PCR. Results. Myocardial I/R increased the levels of cTnI, cTnT, LDH, and CK-MB in diabetic rats. Damaged and irregularly arranged myocardial cells were also observed, as well as more serious ALI with higher lung injury scores and WET/DRY ratios and lower PaO2. Moreover, the expression of key proteins of endoplasmic reticulum stress (ERS) was increased by I/R injury, including phosphorylated- (p-) PERK, p-IRE1ɑ, and ATF6, as well as decreased levels of apoptosis. These effects were all significantly reversed by OMT treatment. Conclusions. OMT protects against ALI subjected to myocardial I/R by inhibiting ERS in diabetic rats.
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高影响因子
Laser & Photonics Reviews
·
2025
·Vol. 19
·期 8
·2401888
·
IF 10
Jie Zhang,Fei Xu,Xiuyan Gao,Zhaojiang You,Yongsheng Gao,Duanqi Ma,Bin Xia,Dehua Wang,Shufang Zhang,Kai Wang
2D bismuth-based perovskites have attention as a potentially transformative technology in optoelectronics due to their exceptional non-toxic and environmentally friendly properties. However, their practical applications are hindered by the low luminous efficiency caused by self-trapped excitons (STEs) under normal environmental conditions. Here, a new composition of lead-free ultrathin 2D perovskite nanosheet iso-octylamine bismuth bromide [(i-OA) 3 BiBr 6 ] is synthesized, with thicknesses down to 1.1 nm, using a solution-based method and explored their stability. Notably, the behavior of STEs in these ultrathin nanosheets can be modulated through a pressure treatment strategy. After completely releasing the pressure, an optimal lattice distortion is stabilized, resulting in an 80-fold increase in irreversible pressure-induced emission. This finding highlights the critical roles of steric hindrance and hydrogen bonding cooperativity effects in the organic cationic layers, along with OA ligand passivation, in enhancing STE radiation recombination under ambient conditions. This advancement opens new possibilities for creating stable, bright STEs under ambient conditions, thus facilitating its potential applications in the fields of pressure sensing, display, and energy savings.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2019
·
IF 5.107
Weiguang Wang,Gequn Shu,Hua Tian,Xiuping Zhu
The treatment of heavy metal ions in wastewater is of great significance for protecting the environment and human health. To improve the power density and removal efficiency of thermally regenerative ammonia electro-deposition battery and expand the concentration range of effective wastewater removal, a new method for removing Cu(II), Co(II), Ni(II) and Ag(I) from wastewater while generating high-power electric energy by using waste heat, called bimetallic thermally regenerative electro-deposition battery (B-TREB), was constructed in this work. For Cu(II)-containing wastewater with a wide concentration range of 0.002–0.3 M, the removal efficiency (RE) of Cu/Zn-TREB could reach more than 90%. With the initial concentration of Cu(II) being increased from 0.0005 to 0.3 M, the peak power density was enhanced from 20 to 546 W m −2 . Besides, for 0.01 M and 0.1 M Co(II) wastewaters, the REs of Co/Zn-TREB were 85% and 90%, respectively. The RE of Ni/Zn-TREB was 88% for 0.01 M Ni(II) wastewater. These results illustrated that B-TREBs could remove many kinds of heavy metal ions in the wastewaters while maintaining a high removal efficiency of ~90% over a wide concentration range, and the produced high-power electricity could provide energy for further treatment or other uses.
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International Journal of Electrochemical Science
·
2023
·Vol. 12
·期 3
·1915-1928
·
IF 1.5
Li Feng,Shengtao Zhang,Song Yan,Shenying Xu,Shijin Chen
In order to explore the corrosion inhibition mechanism of 1-vinyl-3-hexylimidazolium iodide with different concentration for mild steel in 0.5M H 2 SO 4 at 298K, experimental and theoretical studies were carried out. Not only weight loss but also electrochemical experiments reveal that 1-vinyl-3-hexylimidazolium iodide ([VHIM]I) has higher inhibition efficiency. And all experiments have good consistency. The inhibition efficiency was more than 96% comparing with the blank when the concentration was 5mM. It indicates that [VHIM]I adsorbed on the surface of invested metal by forming a film to protect metal. In addition, SEM observation and ATR-IR spectra was used to further confirmed the above. The Langmuir adsorption isotherm was the most proper adsorption model for the adsorption of [VHIM]I molecule on mild steel surface. Moreover, theoretical calculation and molecular dynamic (MD) simulation also manifest that [VHIM]I was absorbed mightily on the metal surface in a parallel mode.
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Science China-Materials
·
2020
·Vol. 64
·期 1
·158-168
·
IF 6.098
Fang Cong,Li Ye,Cai Yuting,Zhou Tian-Liang,Tang Xueyuan,Xie Rong-Jun
Cesium lead halide perovskite nanocrystals (NCs) have attracted unprecedented attention owing to their compelling properties for optoelectronic applications. Compared with the classical hot-injection method, the room-temperature (RT) synthetic strategy is more facile and tender, but it is hard to obtain stable CsPbI 3 NCs and it usually uses polar solvents that sometimes reduce the stability and properties of NCs. Here, we reported a simple approach to synthesize highly efficient and stable CsPbI 3 as well as other color-tunable CsPbX 3 NCs with high quantum efficiency at room temperature via an anion exchange at the water-oil interface, in which the as-synthesized pristine CsPbBr 3 NCs in toluene were treated in aqueous solutions of HX (X=Cl, Br, and I) and protonated oleylamine (OAm) acted as a carrier. The synthesized CsPbI 3 NCs had an emission at 680 nm and even showed excellent colloidal stability after being stored for 32 d. The high efficiency and stability of the obtained CsPbX 3 NCs were ascribed to the facts that: (i) the polar reagents were almost removed from the surface of NCs; (ii) the defect-related nonradiative recombination was suppressed efficiently by surface passivation.
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Nanoscale
·
2026
·
IF 5.1
Limeili Tian,Miaomiao Yang,Jing Wang,Shuai Yang,Chunxu Han,Yangyang Huang,Qingqiang Meng,Aiping Wu
Photocatalytic degradation is an eco-friendly method for decomposing tetracycline hydrochloride (TC), yet it faces challenges such as slow photogenerated carrier transfer, poor separation efficiency, and limited active sites. Semiconductor composites offer a promising solution to enhance catalytic efficiency. In this context, a novel 0D/2D BiOCl 0.7 I 0.3 /Bi 2 MoO 6 (BOCI-BMO) direct Z-scheme photocatalyst was synthesized via a solvothermal method, featuring 0D BiOCl 0.7 I 0.3 quantum dots anchored on 2D Bi 2 MoO 6 nanosheet. The composite photocatalyst with an optimal BOCI to BMO mass ratio of 7:3 (50 mg), achieved over 94% removal of TC (10 ppm) in 40 minutes, demonstrating excellent cyclic stability and broad applicability. Both theoretical calculations and experimental results confirm that the photogenerated carrier transport between semiconductors follows a Z-scheme mechanism, significantly enhancing carrier separation efficiency while preserving strong redox capabilities. Moreover, the unique 0D and 2D structures provide a large specific surface area, offering abundant active sites and reducing carrier transport distance, thereby boosting photocatalytic performance. This study provides theoretical and experimental insights for designing and synthesizing novel visible light-responsive photocatalysts.
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Materials Today Nano
·
2026
·
IF 7.6
Chaohui Zhou,Qi Zheng,Nengqin Jia
I/N co-doped carbonized polymer dot nanozyme was synthesized using DTA, PEI and RhB as precursors. • The DAP CPDs exhibited exceptional peroxidase-like activity, fluorescence property and specific recognition of Hg 2+ . • A portable smartphone-assisted paper-based colorimetric sensing platform for on-site visual detection of Hg 2+ was constructed. • The proposed sensing platform has simplicity, portability, and potential versatility. Mercury ion (Hg 2+ ) pollution poses a serious threat to ecosystems and human health owing to its high toxicity, environmental persistence, and bioaccumulative nature. The development of rapid, cost-effective, on-site visual detection methods for Hg 2+ is paramount but challenging. In this work, we developed a novel iodine/nitrogen co-doped carbonized polymer dots nanozyme (DAP CPDs) via a simple hydrothermal method, which exhibits excellent peroxidase-like activity. Based on the specific inhibitory effect of Hg 2+ on the enzymatic activity of DAP CPDs, a solution-based colorimetric sensor was constructed for the rapid and sensitive visual detection of Hg 2+ , achieving a detection limit of 13.21 nM. Furthermore, A smartphone-assisted, portable paper-based sensing platform was developed by integrating smartphones with paper devices, enabling rapid, cost-efficient, convenient and on-site visual analysis of Hg 2+ in real water samples. This work not only offers insights into the design of high-performance carbonized polymer dot nanozymes, but also presents a practical and portable tool for the on-site monitoring of heavy metal ions in the environment. Schematic diagram of the preparation of DAP CPDs nanozyme and the detection of Hg 2+ by smartphone-based paper device colorimetric platform. Download: Download high-res image (387KB) Download: Download full-size image
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FOOD HYDROCOLLOIDS
·
2026
·
IF 13.8
Xueting Zhang,Chuying Huo,Pengfei Shan,Niping Chen,Quanwei Zhang,Hauyee Fung,Wenting Zhao,Jing Li,Peili Zhu,Shanlong Tang,Ye Yuan,Lin Sun,Junmei Xia,Xuwei Liu,Lifeng Li,Yifa Zhou,Quanbin Han
The functions of polysaccharides are governed by their structures, making sample purity essential for robust structure-activity studies. Polygalacturonic acid (PGA) is widely used as a reference hydrocolloid in bioactivity and materials science research. However, commercial PGA is frequently contaminated with co-purifying polysaccharides, which complicates structure-activity relationship studies. This study identifies a prevalent impurity in commercial PGA and reveals its previously unrecognized, dual role in governing both immunostimulatory activity and hydrogel properties. Using chromatographic methods combined with enzymatic strategies, we isolated two distinct impurities and further purified PGA (pPGA). The impurities were determined to be a free β-1,4-galactan (Galactan) and a rhamnogalacturonan I decorated with β-1,4-galactan side chains (RGI) by structural analyses via MS, NMR, methylation and oligosaccharide profiling. Among them, only the RGI—which naturally carries galactan side chains—triggered a significant immune response in RAW264.7 cells, activating MAPK signaling and increasing levels of NO, IL-6, IL-1β, and TNF-α In contrast, neither the pPGA nor the other impurity, Galactan, showed any immunostimulatory activity. Critically, this bioactive RGI was also essential for material properties. Its removal from commercial PGA markedly weakened the Ca 2+ -crosslinked gels, leading to reductions in both storage (G′) and loss (G″) moduli and resulting in a fragile microstructure. In contrast, the removal of the Galactan did not significantly affect the properties of the hydrogel. Our findings demonstrate that a co-purifying RGI, not PGA itself, is the decisive factor for key biological and physical functionalities attributed to commercial PGA. This finding emphasizes the importance of using structurally defined polysaccharides standards for accurate mechanistic research and controlled biomaterial design.
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JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
·
2026
·Vol. 74
·期 30
·23556-23575
·
IF 6.7
Li Wennian,Huang Yujie,Su Hualing,Nong Jiale,Liang Wenyu,Liu Yonghong,Zhao Longyan,Yuan Qingxia
Pectic
polysaccharides hold therapeutic potential for ulcerative
colitis (UC). This study reports the first isolation of two structurally
distinct pectins from Avicennia marina fruit pericarp: AMPP-2-1 (158 kDa), a rhamnogalacturonan-I (RG-I)-rich
pectin with galactan branches and intricate arabinan side chains rich
in β-Ara f terminals; and AMPP-2-2 (16 kDa),
a low-molecular-weight homogalacturonan (HG)-rich pectin with unsaturated
Gal p A at the nonreducing ends. Both pectins significantly
ameliorated dextran sodium sulfate-induced UC by suppressing inflammation,
restoring intestinal barrier integrity, and modulating gut microbiota
to enrich beneficial bacteria while depleting pathogenic bacteria,
alongside promoting short-chain fatty acid production. Low-molecular-weight
HG showed greater ameliorative effects than RG-I under the present
experimental conditions. These findings establish that pectins may
contribute, at least in part, to the intestinal benefits of A. marina fruits in traditional use, expanding the
structural diversity and biomedical applications of pectic polysaccharides
from underexplored plant resources.
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Green Energy & Environment
·
2026
·
IF 16.7
Na Wang,Wenting Lu,Fengyan Han,Weiping Xiao,Xiaofei Yang
The electron density of Ce active center is modulated via constructing the Ce–O–Bi configuration in Ce-doped BiOX (X = Cl, Br, I). • Halogen-induced differences in electronegativity and ionic radius effectively modulate Bi–O lattice symmetry and electronic properties. • The optimal 2.5%Ce-BOB catalyst delivers excellent H 2 O 2 selectivity, high production yield and favorable 2e - ORR kinetics. • In-situ electro-generated H 2 O 2 realizes efficient electro-Fenton degradation of organic dye pollutants. The selectivity of two-electron oxygen reduction reaction (2e - ORR) is predominantly determined by the adsorption strength of the key intermediate *OOH on the catalyst active sites, which has often been tuned by 3d transition-metal doping. Herein, we fabricate rare earth Ce doped bismuth oxyhalide (BiOX, X = Cl, Br, I) catalysts. The built in Ce–O–Bi local configuration triggers efficient charge rearrangement and tunes the surface electron density of Ce active centers. Meanwhile, the differences in ionic radius and electronegativity among halogen species can modulate the symmetry of the Bi–O lattice, thereby forming a typical volcano-type correlation between the bond length and 2e - ORR catalytic performance. The synergistic effect of Ce doping and halogen modulation endows the 2.5%Ce-BOB catalyst with optimal 2e - ORR performance. It delivers a H 2 O 2 selectivity of over 90% within the potential range of 0.2-0.6 V and achieves a H 2 O 2 production rate of 2631.4 mmol g -1 h -1 at 0.1 V. Furthermore, this optimized catalyst demonstrates potential application in organic wastewater treatment, where the degradation efficiency of methylene blue (MB) reaches approximately 95% in 40 min and that of rhodamine B (RhB) approaches 99% in 15 min. This work provides new insights into the rational design of electrocatalysts and environmental applications of electrosynthesized H 2 O 2 via the synergistic regulation of rare-earth metal doping and halogen modulation. The synergistic strategy integrating Ce-doping and halogen modulation finely tailors the electronic environment of Ce active centers, endowing the 2.5%Ce-BOB electrocatalyst with favorable H 2 O 2 selectivity, considerable production capacity and effective electro-Fenton degradation of organic dyes. Download: Download high-res image (284KB) Download: Download full-size image
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INORGANIC CHEMISTRY
·
2026
·
IF 4.6
Yongjing Deng,Xiaodong Zhao,Ning Ding,Yong Yang,Yongkang Zhu,Mengzhu Wang,Shujuan Liu,Yun Ma,Qiang Zhao
Zero-dimensional (0D) organic–inorganic hybrid metal halides are promising phosphors, yet their wide bandgaps typically require ultraviolet excitation, limiting compatibility with commercial blue light-emitting diode (LED) chips. Here, we present an aggregate-engineering strategy to unlock blue-light excitability in 0D copper(I) iodides by modulating the aggregation architecture of Cu–I motifs within a fixed phosphonium-cation framework. Two homologous compounds, (C26H24OP)2Cu2I4 and (C26H24OP)2Cu4I6, were selectively synthesized through simple stoichiometric regulation. Increasing the nuclearity from a dimer to a tetramer strengthens cuprophilic interactions, narrows the optical bandgap from 2.98 to 2.61 eV, and markedly broadens the excitation window into the blue region. Density functional theory calculations further support the aggregation-induced bandgap narrowing by revealing increased inorganic contributions at the band edges in the tetramer. Notably, the tetramer achieves a high thermal stability and moisture tolerance. Finally, a single-component white LED (WLED) based on the tetramer and a 450 nm chip delivers high-quality white light, and a proof of concept for visible light communication enables high-fidelity audio transmission. This work establishes aggregate engineering as an effective design principle for bridging 0D hybrid halides with practical blue-chip pumping and integrated lighting communication platforms.
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JOURNAL OF HAZARDOUS MATERIALS
·
2025
·
IF 11.3
Chao Xie,Pengyu Zhang,Yi Hu,Dandan Yang,Yahui Li,Yulian Li,Jiandong Lu,Zijian Wu,Junyong He,Peidong Hong,Lingtao Kong
Engineering a catalytic and hydrophilic membrane integrated system holds significant environmental implications for fouling-resistant and efficient water purification. The heterojunction Cu 2 O/Ti 3 C 2 T x was successfully synthesized by leveraging the specific interactions between the terminal active groups of MXene and Cu 2 O, effectively addressing the limitations of the catalytic membrane’s performance due to low-dose doping, and enhancing its catalytic activity and hydrophilicity. Here we report a ultra-low Cu(I) loading that achieves ultra-high fouling-resistance and decontamination performance in a self-cleaning Cu 2 O/Ti 3 C 2 T x @PVDF catalytic membrane integrated system. The representative membrane incorporating 1.0 wt% of Cu 2 O/Ti 3 C 2 T x (denoted as M-1.0) as a PMS activator demonstrated the successful performance of long-lasting antifouling and sustainable decontamination across a wide pH range in complex water matrices. The intrinsic Cu(I)/Cu(II) redox cycles was found to be crucial for driving PMS activation and oxidative conversion. Moreover, the Cu 2 O/Ti 3 C 2 T x -functionalized membrane demonstrated enhanced hydrophilicity and fouling-resistance compared to the pristine PVDF membrane. We further investigate the transformation and ecotoxicity of tetrabromobisphenol A and its intermediates within the M-1.0/PMS membrane system, providing valuable insights into the evolutionary dynamics of TBBPA. This work offers innovative perspectives for advancing environmental purification, membrane self-cleaning, and resources utilization technologies.
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危险品化学品经营许可证（带存储）