Scientific Reports
·
2020
·Vol. 10
·期 1
·1-15
·
IF 3.998
Yu Wei,Yang Hu
Two series of cellulose-based antiscalants with different chain architectures, i.e., linear carboxymethyl cellulose (CMC) and branch-shaped carboxymethyl cellulose- graft -poly(acrylic acid) (CMC- g -PAA), were synthesized. The carboxyl groups were distributed on CMC backbone but mainly on the grafted chains of CMC- g -PAA. The addition of CMC and CMC- g -PAA can both increase the surface energy of CaCO 3 scale and decrease its crystal nucleation rate, thereby inhibiting CaCO 3 scale formation. The structural effects of these cellulose-based antiscalants, especially the chain architectures, on the scale inhibition were investigated in detail. High degree of carboxymethyl substitution caused better inhibition effect of linear CMC. However, CMC- g -PAA with an appropriate content of carboxyl groups but high average number of PAA grafted chains can achieve high inhibition performance. Besides, with similar contents of carboxyl groups, CMC- g -PAA showed much better inhibition performance than CMC due to the distinct multi-dimensional spatial structure of graft copolymer in solution, causing the enhanced chelation and dispersion effects. Characterization of CaCO 3 crystal by scanning electron microscopy and X-ray diffraction confirmed that crystal distortion effect obviously existed in CMC but quite minor in CMC- g -PAA. The differences between the scale-inhibition performance of CMC and CMC- g -PAA should be attributed to the different scale-inhibition mechanisms originated in their distinct chain architectures.
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高影响因子
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
·
2020
·Vol. 413
·期 1
·235-244
·
IF 3.637
Guo Haixin,Su Xiaoping,Su Qingfu,Zhuang Wei,You Zhijiao
A portable photothermal immunoassay based on Au-coated magnetic Fe 3 O 4 core-shell nanohybrids (Au-Fe 3 O 4 ) was developed for point-of-care (POC) testing of lipoprotein-associated phospholipase A 2 (Lp-PLA 2 ) on a digital near-infrared (NIR) thermometer. Au-Fe 3 O 4 photothermal materials were first synthesized through reverse micelle method, and then functionalized with polyclonal rabbit anti-human Lp-PLA 2 antibody. A sandwiched immunoreaction was carried out in polyclonal mouse anti-human Lp-PLA 2 antibody-coated microplate using Au-Fe 3 O 4 -labeled antibody as the detection antibody. With formation of sandwich-type immunocomplex, the captured Au-Fe 3 O 4 on the plate converted the light into heat under an 808-nm laser irradiation (1.5 W cm −2 ), thereby resulting in the increasing temperature of the detection solution. The temperature variations relative to surrounding temperature was determined on a portable NIR thermometer. Several labeling protocols with gold nanoparticle, Fe 3 O 4 nanoparticle, or Au-Fe 3 O 4 nanohybrids were investigated for determination of Lp-PLA 2 and improved analytical features were achieved with the core-shell Au-Fe 3 O 4 nanohybrids. Under optimum conditions, Au-Fe 3 O 4 -based immunoassay exhibited good photothermal responses for the detection of Lp-PLA 2 with a dynamic linear range of 0.01–100 ng mL −1 at a low detection limit of 8.6 pg mL −1 . Good reproducibility and intermediate precision were less than 9.7%. Other biomarkers or proteins did not interfere with responses of this system. An acceptable accuracy was acquired for analysis of human serum sample between Au-Fe 3 O 4 -based photothermal immunoassay and commercialized human Lp-PLA 2 ELISA kit.
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高影响因子
CHROMATOGRAPHIA
·
2021
·Vol. 84
·期 3
·219-231
·
IF 2.044
Wang Yu,Zhou Qianru,Yang Wei,Yang Qianzhan,Zhang Xuejing,Yue Xiaochun
Taste-and-odor occurrence has extensive socio-economic impacts on drinking water, which is now a public health concern. Sulfur odorants can significantly affect the esthetic quality of drinking water and arouse unpleasant organoleptic experience of consumers, which can also harm the human body at high concentration levels. Researches on analysis of sulfur odorants in air and environmental water are numerous, while the reports on analysis of them in tap water are few. The analysis of sulfur odorants in tap water is quite different with it in environmental samples owing to the treatment of the water plant, such as the introduction of disinfectants. In this paper, a novel and practical method for determining the dimethyl disulfide (DMDS) and dimethyl trisulfide (DMTS) in tap water and source water by purge-and-trap coupled to gas chromatography–mass spectrometry (GC–MS) analysis was proposed. The evaluations of sample preservation were performed due to the adverse impact caused by the remaining disinfectant in tap water on the analysis of DMDS and DMTS, including the investigation on the selection and the dosage of preservatives. Besides, aspects affecting the preconcentration procedure and GC–MS analysis of DMDS and DMTS were investigated as well. Moreover, the proposed method was validated by five independent laboratories from different regions of China, representing a good linearity with correlation coefficients ( r ) ranged from 0.9990 to 0.9999 for both DMDS and DMTS between the concentrations of 10 ng L −1 and 100 ng L −1 . The method detection limit (MDL) and limit of quantification (LOQ) of DMDS and DMTS were 3 ng L −1 and 10 ng L −1 , respectively. Meanwhile, satisfactory precision and accuracy were also obtained when the method was applied to detect DMDS and DMTS in tap water and source water. The relative standard deviation (RSD) was 0.90–7.3% for DMDS and 1.1–7.6% for DMTS, and the recovery was 81.2–120% for DMDS and 73.6–118% for DMTS. Furthermore, the repeatability limits and reproducibility limits of DMDS and DMTS were acquired, ranging from 0.631 to 5.71 at low, medium and high concentrations. The proposed method is an effective, environmentally friendly, and promising approach for routine monitoring of DMDS and DMTS in tap water and source water.
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Microfluidics and Nanofluidics
·
2021
·Vol. 25
·期 2
·1-13
·
IF 2.529
Ge Xue-hui,Du Yu-han,Huang Xiaolian,Mo Liangji,Wang Hongxing,Qiu Ting
In this paper, the peppermint oil/HP-β-CD (2-hydroxypropyl-β-cyclodextrin)/chitosan composite microcapsules were prepared. The release ability of these microcapsules was improved for peppermint oil through the combination of molecular encapsulation by HP-β-CD and physical encapsulation by chitosan shell. First, stable peppermint oil/HP-β-CD pre-emulsion was prepared by stirring, based on which the optimal conditions were determined for producing the pre-emulsions with the highest encapsulation efficiency. Then, the pre-emulsion was moved into the flow-focusing microfluidic device as the inner phase and was cut into droplets by chitosan aqueous solution as the middle phase and the octanol as the outer phase to obtain templated emulsions. They were collected using a Petri dish with n-octane coagulation bath containing glutaraldehyde and 2 wt% span80 to be cured into microcapsules. The crosslinking time and the ratio of HP-β-CD in the templated emulsions were adjusted to investigate their impact on the microcapsule structures and correspondingly the capability of the microcapsules to retain peppermint. It was found out that the extended crosslinking time and the addition of HP-β-CD can improve the capability of the composite microcapsules to retain peppermint oil. It provides a straightforward method to produce composite microcapsules. Besides, the microcapsules with improved retaining ability were obtained by combing molecular and physical encapsulation, thus laying a foundation for the exquisite, efficient and polylaminate protection of the volatile perfume or other physically or chemically active components.
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高影响因子
CANCER GENE THERAPY
·
2021
·Vol. 29
·期 1
·101-121
·
IF 5.987
Pan Jiongwei,Huang Gang,Yin Zhangyong,Cai Xiaoping,Gong Enhui,Li Yuling,Xu Cunlai,Ye Zaiting,Cao Zhuo,Cheng Wei
Significantly high-expressed circFLNA has been found in various cancer cell lines, but not in lung cancer. Therefore, this study aimed to explore the role of circFLNA in the progression of lung cancer. The target gene of circFLNA was determined by bioinformatics and luciferase reporter assay. Viability, proliferation, migration, and invasion of the transfected cells were detected by CCK-8, colony formation, wound-healing, and transwell assays, respectively. A mouse subcutaneous xenotransplanted tumor model was established, and the expressions of circFLNA, miR-486-3p, XRCC1, CYP1A1, and related genes in the cancer cells and tissues were detected by RT-qPCR, Western blot, or immunohistochemistry. The current study found that miR-486-3p was low-expressed in lung cancer. MiR-486-3p, which has been found to target XRCC1 and CYP1A1, was regulated by circFLNA. CircFLNA was located in the cytoplasm and had a high expression in lung cancer cells. Cancer cell viability, proliferation, migration, and invasion were promoted by overexpressed circFLNA, XRCC1, and CYP1A1 but inhibited by miR-486-3p mimic and circFLNA knockdown. The weight of the xenotransplanted tumor was increased by circFLNA overexpression yet reduced by miR-486-3p mimic. Furthermore, miR-486-3p mimic reversed the effect of circFLNA overexpression on promoting lung cancer cells and tumors and regulating the expressions of miR-486-3p, XRCC1, CYP1A1, and metastasis/apoptosis/proliferation-related factors. However, overexpressed XRCC1 and CYP1A1 reversed the inhibitory effect of miR-486-3p mimic on cancer cells and tumors. In conclusion, circFLNA acted as a sponge of miR-486-3p to promote the proliferation, migration, and invasion of lung cancer cells in vitro and in vivo by regulating XRCC1 and CYP1A1.
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高影响因子
POLYMER BULLETIN
·
2021
·Vol. 79
·期 3
·1615-1626
·
IF 2.87
Yang Rui,Hao Boran,Zhang Kan
The cleavage of the oxazine ring of benzoxazine resins generally requires high energy during the ring-opening polymerization, which leads them to be processed at a much higher temperature than the traditional thermoplastics. In this paper, a bio-based substance, L-histidine, has been used as the catalyst to lower the ring-opening polymerization of the well-commercialized benzoxazine resin (BA-a) based on aniline and bisphenol-A. The catalytic effect of L-histidine on the polymerization behaviors of benzoxazine resin (BA-a) has been monitored by differential scanning calorimetry and in situ Fourier transform infrared spectroscopy. In addition, L-histidine has also been found to be a good property modifier for BA-a-derived thermosets. The thermal properties of resulting polybenzoxazines have been investigated by thermogravimetric analysis and dynamic thermomechanical analysis. Notably, the thermoset derived from BA-a with adding only 5 mol% L-histidine exhibits excellent thermal stability in consideration of high T g (206 °C), high T d10 temperature (319 °C) and high chair yield value (40%), making this thermosetting resin a promising material for high-performance applications.
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高影响因子
ARCHIVES OF VIROLOGY
·
2021
·Vol. 166
·期 3
·871-879
·
IF 2.574
Zhang Xinyu,Liu Xiaoyu,Wu Xiaodong,Ren Weijie,Zou Yanli,Xia Xiaoli,Sun Huaichang
African swine fever (ASF), caused by African swine fever virus (ASFV), was first reported in Kenya in 1921, but an effective vaccine or antiviral drug is still not available for ASFV control. Rapid and effective diagnostics are key steps in managing ASF. We generated two monoclonal antibodies (MAbs) against the ASFV phosphoprotein P30 and designated these as 3H7A7 and 6H9A10. Epitope mapping revealed that MAb 3H7A7 and 6H9A10 recognized aa 144-154 and aa 12-18 of P30, respectively. A signal-amplified sandwich colloidal gold test strip for rapid detection of ASFV was developed based using these MAbs. Sensitivity and specificity analysis showed that the detection limit of the strip was 2.16 ng of P30. The strip only reacted with ASFV and did not react with other common porcine viruses. In detection tests using 153 clinical field samples including sera, plasma, anticoagulant-treated blood, and tissue, the strip had 95.42% concordance with real-time PCR. The new MAbs specific for P30 and the rapid colloidal gold test strip helped to reveal novel B cell epitopes in P30 and provide an efficient diagnostic test for on-site clinical detection of ASF.
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高影响因子
MICROCHIMICA ACTA
·
2021
·Vol. 188
·期 1
·1-8
·
IF 5.833
Gao Ruru,Wang Junhong,Wang Han,Dong Wei,Zhu Junwu
A new method based on coordination polymer nanoparticles (CPNs) derived from nucleotides and Tb 3+ ions (GMP/Tb) for the selective and sensitive determination of aqueous 2,4,6-trinitrophenol (TNP) (picric acid) is established. The fluorescence of GMP/Tb nanoparticles is effectively quenched by TNP via photo-induced charge transfer (PCT), thus achieving its selectivity toward TNP over other nitroaromatic explosives. The decreased fluorescence of GMP/Tb shows a good linear relationship to the concentrations of TNP ranging from 5.0 to 40.0 μM, and the limit of detection is 26.0 nM (5.96 ppb). The proposed GMP/Tb probe also achieves satisfactory results in real samples. The obtained recoveries of this method in river water samples are in the range 93.15–106.10%. The relative standard deviation (RSD) are 0.57 to 1.01% based on three repeated determinations. This fabricated detector provides a feasible path for determination of ppb-level TNP in natural water samples, which can help humans to avoid TNP-contaminated drinking water.
Graphical abstract
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高影响因子
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS
·
2021
·Vol. 32
·期 4
·4393-4403
·
IF 2.478
Liu Wei,Yao Tingting,Jia Kun,Gu Jianyu,Wang Donghong,Wei Xuehong
A flexible multi-walled carbon nanotubes (MWCNTs)/waterborne polyurethane (WPU) composite film was prepared via in situ polymerization followed by a facile blade coating process. An ultrahigh MWCNTs content of 48.1 wt% was obtained in this film, where MWCNTs without modification of acid or surfactant were uniformly dispersed in the WPU matrix. Therefore, the obtained film exhibited a high electrical conductivity of 16.67 S cm −1 and thermal conductivity of 5.31 W m −1 K −1 . Moreover, an outstanding EMI SE of 65.3 dB at the frequency of 110 MHz was achieved with a film thickness of 80 μm, which can screen 99.9999% of incident wave at such frequency. The EMI shielding performance of this film is comparable to those of other polymer-based shielding composites with larger thickness (0.5–2 mm) ever reported. Furthermore, excellent flexibility and durability of composite films were demonstrated by bending test, indicating that it is a promising candidate for thermal conduction and EMI shielding of portable and wearable devices.
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高影响因子
MICROCHIMICA ACTA
·
2020
·Vol. 187
·期 10
·1-12
·
IF 6.232
Li Zhe,Chen Xiaolan,Yu Lei,Li Huijuan,Chen Lu,Kang Qi,Shen Dazhong
A smartphone-based ratiometric fluorescence device was designed to monitor the reaction kinetic process under vigorous mixing conditions, demonstrated by the hydrolysis of Cs 4 PbBr 6 nanocrystals (NCs). In the presence of trace water, part of Cs 4 PbBr 6 NCs (non-fluorescent) was converted to CsPbBr 3 NCs (strong fluorescent). Using anthracene as the reference fluorophore, the brightness ratio of the green (from CsPbBr 3 NCs) to blue (from anthracene) components in the fluorescence image which was recorded in situ by the smartphone camera was measured as the signal for kinetic analysis. It was shown that the water-triggered conversion reaction from Cs 4 PbBr 6 NCs to CsPbBr 3 NCs follows the pseudo-second-order kinetic model in the early rapid hydrolysis stage (up to 4 min). With increasing water content, the hydrolysis of Cs 4 PbBr 6 NCs is promoted to yield more CsPbBr 3 NCs, which was used to determine trace water in n -hexane, dichloromethane, and toluene with detection limits of 0.031, 0.043, and 0.057 μL mL −1 , respectively. The device offers the advantages of portability and low cost for rapid field determination of trace water in hydrophobic organic solvents.
Graphical abstract
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高影响因子
CELLULOSE
·
2020
·Vol. 27
·期 16
·9311-9324
·
IF 4.21
Wang Mengdie,Yu Tingting,Tan Ling,Li Wei,Wei Wei,Jiang Man,Liu Dongqi,Zhou Zuowan
Abstract Applications of cellulose nanocrystals (CNCs) in various fields of high value have been and are being widely studied. However, research about the fundamental preparation method has come to a standstill. This work aims to introduce a concept of progressive dissolution of cellulosic fibers and an eco-friendly way of preparing CNCs. By controlling TBAH concentration, the amphiphilicity and dissolving capability of TBAH/H 2 O can be regulated. Through a controlled partial dissolution of cellulose in the solvent, aqueous tetra-butylammonium hydroxide (TBAH), the fiber can be dissolved to make nanoscale particles (CNC suspensions). Polarized light microscopy provides a quantitative evaluation of the progress of dissolution, by which a processing window (43% TBAH/H 2 O, 30 min dissolution at room temperature) for preparing CNCs from cotton pulp has been determined. The multiscale cellulose products, including micron-scale, nanoscale, and well-dissolved products of cellulose, have been separated with the assistance of the derivatization process. There are interestingly homogeneous materials of cellulose I with a needle-like shape in the nanoscale products extracted. Furthermore, the cellulose raw materials can be extended from cotton pulp to wood pulp, bamboo pulp, straw pulp, and microcrystalline cellulose, indicating it to be a universal method. Analysis of XRD patterns of the raw and CNCs indicates that amorphous and less-crystalline cellulose can be precisely and controllably dissolved by the solvent, leaving CNCs. Graphical abstract
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高影响因子
WATER AIR AND SOIL POLLUTION
·
2020
·Vol. 231
·期 4
·1-10
·
IF 1.9
Ning Qin,Dong Haoran,Li Long,Wang Yaoyao,Wang Bin
In this study, the dispersion stability and reactivity of sulfide-modified nanoscale zerovalent iron (SNZVI) coated with different surface stabilizers (i.e., starch, sodium dodecylbenzene sulfonate (SDBS), or carboxymethyl cellulose (CMC)) were investigated. All the three types of surface stabilizers could enhance the dispersion stability of SNZVI but exerted differing influences on the reactivity toward trichloroethylene (TCE) removal. The coating of starch on SNZVI markedly improved TCE removal, which was positively correlated with the enhanced dispersion stability (i.e., more active surface sites). However, although the SDBS and CMC could enhance the dispersion stability of SNZVI, they resulted in an inhibition in TCE removal, especially for CMC. It was presumed that the coated SDBS/CMC on the surface of SNZVI occupied the active surface sites for TCE removal. Besides, the effect of groundwater geochemistry (i.e., pH, Ca 2+ , and humic acid (HA)) was examined. The increasing pH from 5 to 9 led to a slight decrease for all stabilized SNZVI particles. The presence of Ca 2+ or HA exerted distinct influence on the TCE removal by the three stabilized SNZVI. The Ca 2+ /HA exerted an insignificant effect on the reactivity of CMC-SNZVI but markedly decreased the reactivity of starch-SNZVI and SDBS-SNZVI. The varying effects of Ca 2+ /HA should be due to their distinct interactions with different types of stabilizers on the surface of SNZVI.
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高影响因子
危险品化学品经营许可证（带存储）