RSC Advances
·
2014
·Vol. 4
·期 48
·25183-25188
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IF 3.708
Meihua Wang,Weifen Niu,Xin Wu,Lixia Li,Jun Yang,Shaomin Shuang,Chuan Dong
3-Mercaptopropionic acid (MPA)-capped ZnS:Cu/ZnS core/shell quantum dots (QDs) have been synthesized via a facile aqueous coprecipitation method and characterized by fluorescence, UV-Vis absorption, infrared spectroscopy and transmission electron microscopy. The fluorescence of ZnS:Cu/ZnS could be increased in the presence of uric acid (UA). The affecting factors for the fluorescence of ZnS:Cu/ZnS were examined including pH, temperature and reacting time. Under the optimized conditions, the fluorescence intensity of the ZnS:Cu/ZnS QDs against the UA concentration showed a linear response in the range of 0.66 μM to 3.3 μM with the correlation coefficient (R2) 0.9973 and the limit of detection 0.044 μM. Most relevant molecules and physiological ions had no effect on the detection of UA. The feasibility of the developed method was further demonstrated by determining the concentration of uric acid in human urine samples and the recoveries were 95% ∼ 103%. Our work provides a sensitive, selective and convenient fluorescence method to determine UA in real samples.
研究领域:
分析化学
·
纳米医学
·
生物传感器
·
临床检验
·
分子诊断
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DOI
高影响因子
CATALYSIS TODAY
·
2018
·
IF 4.667
Xiaoyan Liu,Guojun Lan,Panpan Su,Lihua Qian,Tomas Ramirez Reina,Liang Wang,Ying Li,Jian Liu
The hydrogenation of levulinic acid to γ-valerolactone with water as solvent is a crucial reaction for producing fine chemicals. However, the development of highly stable catalysts is still a major challenge. Here, we prepared a Ru nanoparticles incorporated in mesoporous-carbon (Ru-MC) catalyst to achieve high stability in acidic aqueous medium. The Ru-MC showed excellent catalytic performance (12024 h −1 turnover frequency) in the hydrogenation of LA-to-GVL. Compared with Ru supported on mesoporous carbon catalyst (Ru/MC) prepared by conventional wet impregnation method, the Ru-MC showed excellent reusability (more than 6 times) and thermal stability (up to 600 °C). Based on H 2 -TPR-MS characterization, it was proposed that the incorporated structure significantly increased the interaction between Ru nanoparticles and carbon support, which effectively prevent the leaching and sintering of Ru nanoparticles and contributed to increased high reusability and thermal stability of the Ru-MC.
研究领域:
催化化学
·
绿色化学
·
生物质转化
·
纳米材料
·
能源化学
·
有机合成
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高影响因子
Green Energy & Environment
·
2019
·Vol. 4
·期 4
·424-431
·
IF 0
Yangyang Zhang,Xinli Tong,Linhao Yu,Lingwu Meng,Pengfei Guo,Song Xue
The catalytic transformation of furfuryl alcohol and hexose into value-added chemicals have been investigated with a series of polymer-based catalysts including poly(styrenesulfonic acid) (PSS), graphite oxide-doped poly(styrenesulfonic acid) (PSS-GO), and graphite-doped poly(styrenesulfonic acid) (PSS-C). It is found that the selective conversion of furfuryl alcohol to methyl levulinate (MLE) was successfully performed with PSS as the catalyst, in which a 96.4% yield is attained in methanol solvent. Moreover, the efficient dehydration of d -fructose to produce 5-hydroxymethylfurfural (HMF) has also been achieved using PSS-GO as the catalyst, where a 76.5% yield of HMF was obtained in N -methylpyrrodinone solvent. The effects of reaction temperature, time and solvent were investigated. Furthermore, the used catalysts have been respectively characterized by XRD, TG, FTIR, SEM and TEM techniques to reveal the physical properties and structures of these polymeric catalytic materials.
研究领域:
催化化学
·
生物质能源
·
绿色化学
·
有机转化
·
高分子材料
·
可持续化学
·
生物基化学品
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DOI
FUEL PROCESSING TECHNOLOGY
·
2019
·
IF 4.507
Haonan Qu,Bingyi Liu,Guohua Gao,Yiming Ma,Yanmei Zhou,Hua Zhou,Li Li,Yonghong Li,Shengjian Liu
Levulinic acid (LA) is a versatile key building block in the conversion of carbohydrates and it is an important basic chemical with various potential uses. MIL-100(Fe) loading with insoluble lysine functionalized phosphotungstic acid (Lys-PM 2 ) as heterogeneous catalysts have been synthesized for the conversion of glucose to LA in water. The optimized yield of LA is obtained by using Lys-PM 2 to catalyze glucose conversion is comparable to the majority of effective catalysts. The highest yield of LA (57.9%) is obtained at 150 °C for 9 h with 100 mg glucose and 25 mg Lys-PM 2 , since the Brønsted acidity and Lewis acidity of Lys-PM 2 . And the catalyst is able to recycle at least four times. It demonstrates the potential of Lys-PM 2 for the conversion of biomass.
研究领域:
催化化学
·
绿色化学
·
生物质能源
·
有机转化
·
材料化学
·
可持续化学
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DOI
高影响因子
npj Science of Food
·
2026
·
IF 9.7
Luo Chenghua,Fan Xiaohong,Zhou Yakui,Wu Haifeng,Zhang Lei,Zhao Xiangsheng
The early detection of aflatoxins (AFs) and their biosynthetic precursors is vital for preventing mycotoxin contamination, yet conventional extraction methods generate substantial ecological burdens due to excessive organic solvent consumption. Herein, a tailored menthol-propionic acid Natural Deep Eutectic Solvent (NADES) was developed for the simultaneous extraction of 11 AFs and their precursors from lotus seeds. This refined solvent system demonstrated satisfactory extraction efficiency when coupled with UPLC-MS/MS, and a 50% contamination incidence was observed in real samples. Notably, the NADES-based protocol showed practical advantages under the compared conditions, including over 90% organic solvent reduction and 10~20 times faster extraction than conventional methods. The extraction mechanism was further elucidated at the molecular level through integrated density functional theory (DFT) calculations and molecular dynamics simulations (MDs). Quantum chemical analysis revealed energetically favorable hydrogen bonding and hydrophobic interaction between the NADES system and aromatic rings of AFB 1 , while MDs further demonstrated the formation of persistent hydrogen-bond networks. This work provides a viable, eco-friendly strategy for extracting aflatoxins and their precursors, demonstrating a high potential for applications in the extraction of mycotoxins from food, feed, and herbal products.
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高影响因子
FOOD RESEARCH INTERNATIONAL
·
2026
·
IF 8.8
Yaning Nie,Ting Xia,Yihong Fu,Yixie Chen,Jun Wang,Nannan Zhang,Shuxia Huang,Junhong Yu,Min Wang
Dark beer melanoidin (BM) exhibited colloidal properties and negative charge. • Glycosidic, peptide and non-covalent bonds were broken after chemical treatment. • Structure and bioactivity of BM were relatively stable during in vitro digestion. • The levels of polyphenolics and SCFAs were increased during colonic fermentation. • Phloroglucinol was the main phenolic compound during colonic fermentation. Melanoidins are brown macromolecular products of Maillard reaction formed through thermal processing, which provide unique flavor and bioactive function of food. This study aims to reveal the changes of structure and bioactive characteristics in beer melanoidin-rich fraction (BM) during different chemical treatments and in vitro digestion and fermentation. The results showed that BM had colloidal properties with 24.21–99.28 nm and negative charge, which mainly contained carbohydrates. In addition, microscopic morphology showed surface cracks after acid treatment, blocky particles after alkali treatment, and some porous small particles after salt treatment. These might be caused by the disruption of polysaccharide, protein, and the skeleton structure through spectra. Moreover, during simulated in vitro digestion stage, Mw of BM was slightly decreased, which might be due to the breakage of glycosidic bonds. Microscopic morphology presented a relatively complete block structure. However, the contents of total phenolics and flavonoids and the production of short-chain fatty acids were significantly increased during colonic fermentation process. Phloroglucinol was the main phenolic compound and its content also increased during colonic fermentation. Collectively, the results indicated that BM had relative stability during the digestion stage, and released bioactive compounds during colonic fermentation. These findings suggest that BM, as a novel colloidal prebiotic, possesses potential role in intestinal health. Download: Download high-res image (164KB) Download: Download full-size image
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高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Liu Yang,Baoshan He,Ming Lu,Zhengyong Liang,Yao Liu,Wenjie Ren,Yiwei Xu
The core–shell FeNPs@Pt shows excellent catalytic activity and stability. • Selective detection via thiol–Michael addition without enzymes or aptamers. • The color development is rapid and convenient, taking only 150 s to complete. • The suppression–recovery mechanism amplifies the signal and enhances sensitivity. In this study, we propose an innovative Acrylamide (AA) detection platform based on platinum-coated magnetic iron nanoparticles (FeNPs@Pt). The introduction of a platinum shell not only preserves the intrinsic catalytic properties of FeNPs but also significantly enhances their structural stability and catalytic activity. Compared with traditional antibody–aptamer-based detection methods, this platform employs a thiol–Michael addition reaction combined with a nanocatalyst-mediated cascade colorimetric process. This approach overcomes key limitations of antibody–aptamer technologies, such as high cost and operational complexity, enabling rapid and low-cost detection of AA. The mechanism involves a specific Michael addition reaction between AA and 2,2′-(ethylenedioxy)diethanethiol (EDT), which mitigates the inhibitory effect of EDT on the catalytic activity of FeNPs@Pt. Subsequently, the addition of 3,3′-dimethylbenzidine (TMB) triggers a colorimetric reaction within 150 s, rendering the result visible to the naked eye. This sensing platform exhibits a linear response over the range of 1–200 μM, with a detection limit as low as 0.63 μM. Notably, the FeNPs@Pt–EDT–TMB-based colorimetric detection platform not only provides an efficient and low-cost method for acrylamide detection but also offers an innovative solution for on-site food safety monitoring, demonstrating significant application potential. Download: Download high-res image (108KB) Download: Download full-size image
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OPTICAL MATERIALS
·
2026
·
IF 4.3
Dewei Ma,Xiaoyang Qin,Chengdong Wu
Lead-free copper-based halides have attracted significant attention for optoelectronic applications due to their excellent photophysical properties, good stability, and environmental friendliness. However, current synthesis methods for copper-based halide nanocrystals either require high-temperature inert protection or rely on insulating long-chain ligands, limiting their practical applications. In this study, we report a facile one-pot room-temperature synthesis of Cs 3 Cu 2 X 5 (X = Cl, Br) and CsCu 2 I 3 nanocrystals using an anti-solvent method. Short-chain propionic acid (PA) is introduced as a surface passivation ligand, significantly enhancing photoluminescence through defect passivation. The PA-coated Cs 3 Cu 2 Cl 5 nanocrystals exhibit good resistance to ethanol but poor stability in water. To improve thermal stability, PMMA encapsulation is employed, with the composite film retaining ∼90% of initial PL intensity at 80∼90 °C and two-thirds at 150 °C. Time-resolved PL decay measurements confirm that both PA coating and PMMA encapsulation prolong the exciton lifetime. This work provides a green and effective strategy for the synthesis and surface engineering of copper-based halide nanocrystals for environmentally friendly optoelectronic applications.
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高影响因子
npj Science of Food
·
2026
·
IF 9.7
Shi Yuxuan,Sun Jiayi,Chen Lin,Xu Shuang,Guo Shasha,Xu Anan,Ye Qun,Wang Yuefei,Xu Ping
While black tea’s oxidized polyphenols hold potential for gut health, the specific protective mechanisms of its ethanol-soluble fraction (BES), particularly regarding host-microbiota interactions, remain poorly defined. This study elucidated the dual mechanisms through which BES ameliorates dextran sulfate sodium (DSS)-induced colitis in mice. By integrating network pharmacology, molecular docking/dynamics simulations, RT-qPCR, and Western blot analysis, we identified the PI3K/AKT signaling axis as a potential host target. Our findings suggest that key flavonoid constituents stably bind to critical nodes, potentially downregulating the expression and activation of pathway components. Concurrently, 16S rRNA sequencing and metabolomics revealed that BES reshaped gut microbiota by suppressing Akkermansia and enriching SCFA producers such as Lactobacillus , restoring fecal SCFA levels. Fecal microbiota transplantation confirmed that BES-modulated microbiota alone transferred protection. Thus, BES acts concertedly through direct PI3K/AKT inhibition and indirect microbiota-SCFA modulation, providing a mechanistic basis for targeted use of black tea fractions in intestinal inflammation.
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PubMed
高影响因子
Microorganisms
·
2026
·Vol. 14
·期 8
·1814
·
IF 4.7
Huipeng Liu,Xining Geng,Yousi Fu
Pectin oligosaccharides have emerged as promising prebiotics whose biological activities are closely tied to their structural features, particularly monosaccharide composition. However, systematic experimental evidence regarding how different monosaccharide compositions collectively influence gut microbiota modulation, SCFA production, and the metabolomic responses of mixed pectin oligosaccharides remains limited. To address this gap, Pool-I (27.92% galacturonic acid, rich in neutral sugars including galactose, glucose, and arabinose) and Pool-II (98.73% galacturonic acid) were evaluated by comparison with inulin, a reference prebiotic, using an in vitro human fecal fermentation model. Microbial community structure, SCFA production, and metabolomic profiles were assessed at 12 h and 24 h via 16S rRNA gene sequencing, gas chromatography, and untargeted metabolomics, respectively. Inulin exhibited superior enrichment of Actinobacteria (predominantly Bifidobacterium ) and consistently higher total SCFA production (24.07 ± 0.25 mmol/L acetic acid at 24 h vs. 20.27 ± 0.28 and 20.53 ± 0.76 mmol/L for pectin oligosaccharides), particularly propionic and butyric acids. Although Pool-I and Pool-II yielded lower overall SCFA concentrations, they significantly enriched beneficial SCFA-producing genera (including Coprococcus_3 , Butyricicoccus , and Parabacteroides ) at 24 h. Metabolomic analysis revealed that Pool-I uniquely upregulated twenty-six differential metabolites ( VIP > 1, p < 0.05), including taurine ( VIP = 2.40, p < 0.001), L-proline ( VIP = 1.72, p = 0.015), and pantothenate ( VIP = 1.63, p < 0.001), while reducing uric acid ( VIP = 1.05, p < 0.001), whereas only two differential metabolites were identified for Pool-II. We conclude that monosaccharide composition is a key determinant of the prebiotic efficacy of pectin oligosaccharides: Pool-II selectively promotes SCFA-producing taxa, whereas Pool-I elicits broader metabolic regulation. These effects provide a theoretical foundation for developing pectin oligosaccharides as potential prebiotic candidates.
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DOI
PubMed
高影响因子
Nature Communications
·
2026
·
IF 18.1
Zhai Yanjie,Gong Shanhe,Zuo Yunpeng,Sun Libo,Li Weisong,Yang Yile,Xia Qing,Cui Lele,Zhou Yingying,Wu Jie,Zhang Xiao,Wang Xin
Electrochemical hydrogenation of biomass-derived substrates offers a sustainable route to valuable chemicals, yet conventional systems often struggle to simultaneously achieve high efficiency and high product purity. Here we report an electrochemical process based on a porous solid-electrolyte reactor that integrates efficient hydrogenation with intrinsic purification for biomass-derived substrates, thereby eliminating the need for supporting electrolytes. The system promotes the hydrogenation of maleic acid solution (a model unsaturated biomass substrate) into succinic acid (a model saturated biomass substrate), via a cation shielding effect while suppressing competing reactions such as hydrogen evolution. By continuously recycling the generated sodium succinate from the cathode to the middle layer, the reactor further converts it into pure succinic acid, establishing a closed-loop alkali-metal-cation shuttle that enhances selectivity and minimizes side reactions. This system delivers succinic acid Faradaic efficiencies ~ 85%, long-term operational stability (over 500 hours), and a final solution of > 98% purity, without downstream electrolyte recovery. These results highlight a scalable pathway toward cleaner, more efficient electrochemical upgrading of biomass.
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高影响因子
ACS Omega
·
2026
·Vol. 11
·期 32
·47667-47674
·
IF 5.2
Han Lu,Lin Ling,Xu Haiju,Hu Qinjia,Xie Dan
To improve the solubility
and bioavailability of astaxanthin
while
enhancing its processing properties, this study established an eco-friendly,
highly efficient microwave-assisted Z -isomerization
system. We first conducted a systematic screening of various menthol-based
deep eutectic solvents (DESs) to identify the most effective medium
for this conversion. Following the selection of the optimal DES, we
investigated the catalytic effect of three representative natural
sulfur-containing compounds─methyl isothiocyanate (MITC), hexyl
isothiocyanate, and dimethyltrisulfide─under microwave irradiation.
Furthermore, we systematically evaluated the influence of other key
process parameters, including heating method, catalyst dosage, astaxanthin
mass concentration, microwave power, temperature, and duration, through
single-factor experiments. The results demonstrated that the menthol-acetic
acid-based DES provided the most effective reaction environment, and
MITC exhibited the highest catalytic efficacy, achieving a peak total Z -isomer proportion of 36.2% at 60 mg/mL, compared to a
baseline of 6.82% in the catalyst-free control group. Mechanistic
analysis suggests that the electrophilicity of isothiocyanates and
the steric effects of their side chains play critical roles in the
isomerization process. These findings demonstrate that this green
processing system can serve as an efficient and sustainable approach
for the production of Z -isomer-enriched astaxanthin.
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高影响因子
危险品化学品经营许可证（带存储）