JOURNAL OF POLYMER SCIENCE
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2026
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IF 3.9
Jianxiong Cheng,Rui Wang,Ziqian Xu,Qiang Dou,Linlin Wu
DES-based eutectogels suffer from limited mechanical performance due to solvent-induced plasticization, and phase separation alone cannot reliably reinforce network structures. Although metal-salt-based DESs enable coordination reinforcement, how ligand identity regulates coordination environment, phase behavior, and interdomain connectivity remains unclear. Here, we show that ligand-controlled coordination dictates both network formation and phase behavior in intrinsically phase-separating eutectogels. Using poly(N-isopropylacrylamide) (PNIPA) and ZnCl 2 -based DESs with acetamide (AcAm) and ethylene glycol (EG) as ligands of distinct coordination strength, two regimes are identified. In PNIPA/ZnCl 2 –AcAm, weak Zn 2+ –AcAm coordination enables Zn 2+ bridging between polymer chains, suppressing phase separation and forming a homogeneous network with uniform polymer–Zn 2+ interactions, high transparency (> 90%), high elongation (2553%), and tensile strength of 5.21 MPa. In contrast, PNIPA/ZnCl 2 –EG shows strong Zn 2+ –EG coordination, limiting polymer–metal interactions and inducing coordination-stabilized phase-separated domains with reduced transparency (~50%), higher strength (14.45 MPa), and limited elongation (85%). Non-coordinating choline chloride DESs yield weak networks (< 1.3 MPa), confirming that coordination-governed connectivity dominates reinforcement. A mixed-ligand system ([AcAm]/[EG] = 1:2) achieves balanced strength (7.67 MPa) and elongation (1270%). These results establish ligand-controlled coordination as a general strategy to regulate phase separation and interdomain connectivity, enabling simultaneous optimization of strength and stretchability. Graphical Ligand-controlled coordination in metal-salt deep eutectic solvents regulates the competition between polymer–metal and ligand–metal interactions in eutectogels. This coordination balance governs phase separation behavior and interdomain connectivity, leading to either homogeneous or phase-separated networks with distinct mechanical responses. A mixed-ligand strategy enables simultaneous enhancement of strength and stretchability.
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XENOBIOTICA
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2026
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IF 1.5
Jia-ou Chen,Ling-li Zhou,Jian-heng Lin,Hao-tian Zhou,Lai-fang Sun,Cheng-ke Huang
1. This study aims to investigate the effects of orally administered paeoniflorin (PF), a major bioactive compound from Paeonia lactiflora, on cytochrome P450 (CYP450) enzyme activity in rats to assess potential drug-drug interactions (DDIs). Following PF treatment, rats received a mixed probe drug solution containing phenacetin (PHE), tolbutamide (TOL), omeprazole, and metoprolol, and plasma concentrations of the substrates and metabolites were quantified using ultra-high-performance liquid chromatography-tandem mass spectrometry. The metabolic ratio, calculated as the ratio of metabolite to parent drug area under the curve (AUC), was used to evaluate CYP activity.2. Results showed that AUCAcetaminophen/AUCPHE values were significantly elevated in PF-treated groups, indicating induction of CYP1A2, whereas AUCOHTOL/AUCTOL values were significantly reduced, suggesting inhibition of CYP2C11. No significant effects were observed on CYP2C or CYP2D2 activities.3. These findings indicate that PF can modulate CYP1A2 and CYP2C11 activities under the experimental conditions tested, as assessed using PHE and TOL as functional markers. However, the magnitude of these effects was modest and observed only at relatively high PF doses (50 and 100 mg/kg). Given the inherent species differences between rat and human CYP enzymes, direct extrapolation of these findings to human CYP1A2 and CYP2C11 requires further validation in human-relevant models.
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高影响因子
ACS Sustainable Chemistry & Engineering
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2026
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IF 7.6
Xie Wancen,Pan Denghui,Wen Jiahui,Zhao Zexu,Zhou Yitong,Mei Xinyi,Luo Hongbing,An Xiaochan,Shen Lixue,Yu Qingjun,Jiang Li,Tang Peng
Replacing toxic solvents and petrochemical additives in poly(vinylidene fluoride) (PVDF) ultrafiltration (UF) membrane fabrication is essential for advancing sustainable membrane manufacturing. Herein, a greener fabrication route for PVDF UF membranes was developed by employing PolarClean as a green solvent and a nonionic deep eutectic solvent (NIDES) as a green additive at a relatively low temperature. The effects of PVDF concentration, NIDES dosage, and the support layer on phase inversion behavior as well as membrane properties were systematically investigated. The results showed that the NIDES acted as both a pore-forming agent and a surface chemical modifier. At an appropriate dosage, NIDES promoted pore formation and enriched functional groups on the membrane surface. However, excessive addition led to additive deposition and surface heterogeneity. The optimized membrane M5-8P-1DES achieved a pure water permeability of 1040 L m –2 h –1 bar –1 with a sodium alginate rejection of 96.8%. For mechanical property optimization, the support layer was utilized and the supported membrane further increased permeability to 2459 L m –2 h –1 bar –1 . Life cycle assessment showed that PolarClean and NIDES were mostly environmentally preferable to conventional materials. However, under realistic fabrication conditions, the PolarClean-based membrane showed higher impacts in most categories due to higher solvent demand and energy input. Green electricity analysis showed that onshore wind electricity markedly improved its environmental competitiveness, making it the lowest-impact option. This highlights the importance of low-carbon electricity for realizing the sustainability potential of PolarClean-based membrane fabrication. Overall, this study provides both a greener fabrication strategy for PVDF membranes and a clearer framework for assessing truly sustainable membrane manufacturing.
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Nature Communications
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2026
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IF 18.1
Shi Zhiheng,Tang Yongchao,Wei Yue,Liu Guigui,Huang Haolong,Qi Jintu,Feng Zhenfeng,Ye Minghui,Zhang Yufei,Wen Zhipeng,Liu Xiaoqing,Yang Qi,Zhi Chunyi,Li Cheng Chao
Aqueous Zn | |I 2 batteries, involving I - /I 0 /I + redox, are promising yet usually facing low I 2 utilization dominated by I 0 /I + redox, especially under high loadings. Unlocking alternative pathway to I 0 /I + redox, preferably in noncorrosive dilute electrolytes, is a crucial solution. Here, we report a pathway towards more thermodynamically favorable I 0 /I + redox, via a unique carbon-halogen bond substitution. This pathway is realized with a low-concentrated (0.7 M), noncorrosive organohalide additive (2-bromoacetamide, BrAce), triggering a reversible Br-C···I (0) and C-I (+) -Br bond substitution. Compared with conventional interhalogen bonding (I-Br) pathway, this pathway synchronously lowers the barrier for I⁰/I⁺ redox and strengthens the anti-hydrolysis of I + species, by elaborately regulating axial δ hole activity of interhalogen bond (I (δ+) -Br). Notably, this pathway enables sustainable operation of four-electron Zn | |I 2 batteries with high I 2 loading (8.6 ~ 24.0 mg cm -2 ), featuring improved performances: (1) high I 2 utilizations (55% ~ 80%) at high rates (5.8 ~ 46.4 mA cm -2 ), (2) long lifespan ( \( > \) 400 cycles) with practical areal capacity ( ~ 3.85 mA h cm -2 ) and 99.5% retention even at 47.5 mA cm -2 . This pathway opens an exciting research direction to unlock unusual halogen chemistry for scalable, high-energy, sustainable aqueous batteries.
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高影响因子
ADVANCED FUNCTIONAL MATERIALS
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2026
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IF 19
Fan Xue,Tianqiang Yin,Zhiyuan Guo,Jingfu Song,Qingjun Ding,Gai Zhao
High-precision in situ monitoring of tribological interface temperature is essential for the reliable operation of aerospace and advanced tribological systems, yet conventional thermocouples and infrared methods suffer from implantation difficulties, delayed response, and environmental interference. Here, we report a novel multifunctional lubricated nanocapsule that leverages the phase-change behavior of deep eutectic solvents (DES) to overcome these limitations. Structural characterization was performed using scanning electron microscopy (SEM), transmission electron microscopy (TEM), and Raman spectroscopy, and tribological tests were conducted to evaluate both tribological behavior and capacitance-temperature response mechanisms. Experimental results demonstrate that when the interface temperature reaches the melting point of the DES, the capacitance of the tribological system undergoes an abrupt transition, while both the coefficient of friction (COF) and the wear rate decrease to a certain extent. The improvement in dielectric properties is ascribed to the ion polarization effect generated by the molten DES, whereas the enhancement of tribological performance arises from the lubrication protection provided by its liquid phase. This work demonstrates a materials-based strategy for real-time temperature sensing at dynamic tribological interfaces, offering new opportunities for intelligent lubrication and fault prediction in high-end equipment.
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JOURNAL OF COLLOID AND INTERFACE SCIENCE
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2026
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IF 9.6
Shanshan Li,Fanyong Yan,Dongyang Liu,Yu Wang,Wen Li,Cuiyan Zhang,Yang Fu
To achieve room-temperature phosphorescence (RTP) emission, two effective approaches are constructing rigid microenvironments and enhancing intersystem crossing (ISC) efficiency. However, designing highly efficient RTP carbon dots (CDs) remains challenging. Herein, the RTP CDs were fabricated through a synergistic combination of heteroatom doping and matrix-assisted synthesis strategies. The obtained B, N-doped composite materials N-CDs@Na 2 B 4 O 7 exhibit long-lived and color-tunable RTP emission. N-doping with lone-pair electrons facilitates the ISC process, thereby enhancing RTP emission. The boron‑oxygen network in sodium tetraborate (Na 2 B 4 O 7 ) effectively shields RTP emission from environmental quenching. Characterizations including X-ray Photoelectron Spectroscopy (XPS) demonstrated C B and B N bonds, confirming successful encapsulation of N-CDs within the Na 2 B 4 O 7 matrix. The RTP lifetime was extended from 32.79 ms to 122.00 ms with the incorporation of the matrix. The wavelength-dependent RTP color variation under UV excitation enables its application in multi-level information encryption. The detection of berberine hydrochloride (BRH) was based on the inner filter effect (IFE) of the N-CDs@Na 2 B 4 O 7 composite. The combined strategy provides experimental evidence for RTP color regulation. The resulting CDs exhibit excitation-dependent RTP. The resulting CDs demonstrate excellent performance in multi-level information encryption applications. With tunable colors and long lifetimes, making them highly suitable for multi-level information encryption.
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Nature Communications
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2026
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IF 18.1
Xia Shuai,Tan Hao,Zhang Jianfang,Han Miao,Xu Chang,Yu Cuiping,Chen Kui,Zhang Yong,Wu Yucheng,Wang Yan
The electrocatalytic synthesis of amides from abundant small molecules offers a sustainable route for green chemical production, yet faces fundamental challenges due to kinetic competition between C–C and C–N bond formation. Here we show an atomically engineered dual-site catalyst featuring nickel single atoms adjacent to copper nanoclusters (Ni-SA/Cu-NCs) on a nitrogen-doped carbon matrix for efficient CO 2 and NO 3 − co-reduction to acetamide. This architecture enables complementary functions, with Ni sites selectively converting CO 2 to CO and neighboring Cu nanoclusters promoting C–C coupling to form the *CCO intermediate while concurrently reducing NO 3 − to form the *NH 2 intermediate. The resulting synergy facilitates rapid intermediate transfer and C–N coupling, delivering an acetamide yield rate of 257.3 mmol h −1 g cat . −1 at an industrial current density of 215.7 mA cm −2 , with stable operation over 160 h. In situ spectroscopic studies and theoretical calculations suggest that strong Ni–Cu electronic coupling promotes reactant adsorption and reduces the activation barriers for critical steps, including *CO dimerization and *CCO–*NH 2 coupling. This work provides an atomic-level design strategy for multi-site catalysts to steer complex electrocatalytic reactions toward value-added products.
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ACS Sustainable Chemistry & Engineering
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2025
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IF 7.3
Fuhui Luo,Fenfen Zeng,Zhongqiao Zhao,Xu Ren,Yong He,Xia Yang,Fengxiang Zhang,Hanqing Pang,Wei Shi
The development of efficient and green extraction methods to meet the needs of the food and pharmaceutical industries for natural products has received widespread attention. In this work, a novel two-step extraction process for acid-electrolyzed oxidizing water (AOEW) pretreatment with deep eutectic solvents (DESs) (EWDES) was designed. Screening of 25 ultrasound-assisted DESs and EWDESs revealed that the extraction rate of EWDES (chlorine chloride-acetic acid) (ChCl-AA) was significantly higher than that of UADES (ChCl-AA) and traditional solvents. Back-propagation-genetic algorithm proved superior to response surface methodology in robustness and predictive intelligence. The mechanism analysis demonstrated that the addition of AOEW significantly enhanced the destruction of the cell wall structure, facilitating the entry of DESs into cells and promoting the formation of hydrogen bonds with components, which aid in the delivery of active ingredients. Notably, the addition of AOEW further promotes the formation of hydrogen bonds between DESs and the active ingredients. The EWDES system demonstrates multifunctional capabilities in enhancing the natural product extraction efficiency through synergistic mechanisms. Furthermore, the green evaluation tools validated the environmental sustainability of EWDES.
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Journal of Environmental Chemical Engineering
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2025
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IF 7.2
Wensheng Wu,Lingzhi Huang,XiuShuai Guan,Xiaochao Zhang,Changming Zhang,Jinbo Xue
Photocatalytic reduction of CO 2 is a promising strategy for the conversion of high value-added chemicals, but the difficulty lies in the design of photocatalysts that combine high electron transfer efficiency, activity and stability. In this paper, the pore structure and the number of active sites of carbon spheres were modulated to promote the adsorption and reduction of CO 2 . MBZCSs-40 achieved a CO yield of 28.23 μmol g -1 for 8 h. N 2 adsorption and desorption and SEM confirmed the existence of a hierarchical pore structure. XPS showed that the ratio of the introduced pyridine nitrogen groups was well linearly correlated with the reducing properties and was hypothesized to be the main active centers. CO 2 adsorption isotherms revealed that MBZCSs-40 had the highest adsorption capacity of 1.86 g. In situ infrared detected that CO 2 was adsorbed on the nitrogen active sites and converted to CO 2 *, followed by the generation of the key intermediate COOH* in the presence of e - and H + . The moderate amount of nitrogen doping promoted micropores generation and thus exposed more active sites. Pyridine nitrogen enhanced the adsorption and activation of CO 2 and promoted the generation of COOH*. This study provides a new perspective for the design of nitrogen-doped metal-free photocatalysts.
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高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9
Jing Fan,Jingfan Huang,Fenhong Song,Nan He,Xu Wang
Efficient carbon capture technologies are crucial for mitigating climate change amid escalating CO₂ emissions. Traditional solvents like monoethanolamine (MEA) suffer from limitations such as high energy consumption and degradation. This study synthesized eight novel phase-change deep eutectic solvents (DESs) via a one-step process, combining 2-amino-2-methyl-1-propanol (AMP) as hydrogen bond donor (HBD) with acetamide, tetraethylammonium chloride, tetrabutylammonium bromide, and tetrabutylphosphonium bromide as hydrogen bond acceptors (HBAs) at 1:4 and 1:6 ratios. It addresses the critical challenge of developing absorbents concurrently featuring high CO₂ capacity, excellent stability, and environmental benignity. DES density decreased linearly while viscosity declined exponentially with temperature, with negligible toxicity as predicted by ECOSAR. Acetamide-based DESs exhibited the highest thermal stability (132.67 °C). Dual absorption mechanisms were observed: chemical reaction dominated at low pressures (0–0.2 MPa), while physical absorption governed by Henry's law prevailed at high pressures (0.2–0.7 MPa). The acetamide/AMP (1:6) DES achieved a maximum capacity of 3.29 mol·kg −1 at 323.15 K, significantly outperforming MEA. Cyclic absorption-desorption experiments confirmed the excellent regenerability of the solvents, particularly the acetamide-based DES, which maintained a regeneration efficiency of over 80% after three cycles. Fourier Transform Infrared Spectroscopy (FTIR) confirms the occurrence of chemical reactions during the absorption process. When deep eutectic solvents absorb CO₂, insoluble carbamates are formed, which leads to phase change. Phase-change deep eutectic solvents are promising candidates for next-generation materials in the field of efficient and sustainable industrial CO₂ capture.
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ACS Applied Polymer Materials
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2026
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IF 4.7
Ziqian Xu,Rui Wang,Jianxiong Cheng,Xiaofeng Ma,Ling Zhang,Linlin Wu,Qiang Dou
Deep eutectic solvent (DES)-based eutectogels are emerging as promising candidates for flexible sensors owing to their intrinsic ionic conductivity, nonvolatility, biocompatibility, and cost-effectiveness. However, conventional eutectogels are typically mechanically weak, as they lack efficient mechanisms to dissipate energy through reversible molecular interactions. In this work, we demonstrate the rational design of transparent and ultratough eutectogels achieved by in situ polymerization of sulfobetaine vinylimidazole (VIPS) in a ZnCl2–acetamide (ZnCl2–AcAm) Type IV metal-salt DES. In this system, the sulfonate groups on PVIPS chains dynamically coordinate with Zn2+, while the adjacent imidazolium rings stabilize these interactions through dipole–dipole and π–π associations. Meanwhile, acetamide molecules form extensive hydrogen bonds with sulfonate and imidazolium groups of PVIPS, providing an additional dynamic cross-linking network. The resulting eutectogel exhibits outstanding mechanical performance with a tensile strength of 3.95 MPa, toughness of 19.78 MJ m–3, stretchability of 683%, and high optical transparency of 90%. The eutectogels also display multifunctional features including self-healing, adhesion, shape memory, and stable mechano-ionic coupling, which enable sensitive responses to strain, pressure, and temperature. These results establish the integration of zwitterionic polymers with metal-salt DESs as a distinctive strategy for designing adaptive eutectogels, advancing the development of flexible and wearable electronics.
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NEW JOURNAL OF CHEMISTRY
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2026
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IF 2.5
Xiaojun Bao,Yu Cao,Lei Gong,Renjiang Li,Dongshun Deng
As an important and free amino acid, taurine (Tau) shows extensive application in pharmaceuticals. The coexistence of inorganic salts during the production process affects the purity and quality of Tau. Present study firstly described a novel method to separate Tau and Na2SO4 by forming deep eutectic solvents (DESs) in situ. Ethanolamine (MEA) was chosen as the optimal hydrogen bond donor to pair with Tau. After removal of Na2SO4, taurine was stripped out from in situ DES using n-propanol as reverse solvent with the yield of 98% and trace impurities (Na2SO4 and NaCl contents less than 13.70 mg•g -1 and 12.93 mg•g -1 , respectively). On the optimized parameters, the Tau purification and separation process were further elucidated using quantum chemical calculations and molecular dynamics simulations together. Results showed the interaction energy of 116.1 kJ/mol between MEA and Tau, confirming the superiority of Tau purification using DES in situ.
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危险品化学品经营许可证（带存储）