ATMOSPHERIC ENVIRONMENT
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2026
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IF 3.8
Jin Zhang,Jianze Zhang,Yifan Qiao,Xinxing Zhang,Yifan Meng
Direct capture of carbon dioxide (CO 2 ) by organic amines is often inefficient in bulk aqueous solutions under mild conditions, whereas microdroplets provide a unique gas-water interfacial environment that enables the transformation. However, whether CO 2 capture occurs from the gas side or the water side of the microdroplet interface remains unclear. Here we show that amines capture CO 2 predominantly on water microdroplets to form carbamates, suggesting that the gas–water interface plays a key role in this process. In the presence of dipropylamine vapor, spraying water microdroplets generates a carbamate anion which is directly detected by mass spectrometry (MS) and tandem mass spectrometry (MS 2 ). Control experiments show that removing dissolved CO 2 from water has little effect on product formation, whereas replacing the surrounding gaseous CO 2 with N 2 strongly suppresses the carbamate signal. These results indicate that CO 2 capture occurs predominantly from the gas side rather than from the water side of the gas–water interface. Comparison of vapor-phase amine and dissolved amine conditions shows that the carbamate formation occurs more readily when the amine is introduced from the gas side of the gas–water interface. Water microdroplets are also found to be more effective than other organic solvents, demonstrating that water provides a unique interfacial environment for efficient CO 2 -capture and stabilization of the product. Primary and secondary amines give analogous products, whereas a tertiary amine does not, further supporting carbamate formation. This work suggests a directional role of the gas–water interface in amine-mediated CO 2 capture and provides preliminary mechanistic insight into gas uptake at microscopic aqueous interfaces.
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JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY
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2026
·
IF 16.8
Xue Li,Wei Li,Yanqin Fu,Jianhua Zhang,Sen Yang,Zifeng Hu,Junhao Zhao,Yongbo Cao,Jian Zhang,Yulei Zhang
The laser ablation mechanism of PDC-SPS HfC x N 1 − x ceramics was clarified. • At 39.8 MW m –2 heat flux, HfC 0.75 N 0.25 shows superior ablation resistance. • Dislocations, lath-like structures and dense Hf(C,N,O) layers stabilize ablation. Hafnium carbonitride (HfC x N 1− x ) ceramics show great potential for thermal protection systems due to their ultra-high melting point, and investigating their ablation behavior is essential for their application under extreme conditions. In this work, HfC x N 1− x ceramics with varying nitrogen contents were synthesized via polymer-derived ceramic followed by spark plasma sintering. Laser ablation tests showed that HfC 0.75 N 0.25 achieved excellent ablation resistance under the laser power of 500 W, with linear and mass ablation rates of 1.08 µm s −1 and 0.32 mg s −1 , respectively. This is ascribed to the high melting point and exceptional thermal stability of HfC 0.75 N 0.25 , which result from moderate nitrogen incorporation. During laser ablation, dislocation accumulation and the formation of lath-like structures dissipate part of the laser heat flux. Subsequently, a dense Hf(C, N, O) solid solution layer with high viscosity forms, which effectively impedes oxygen diffusion and maintains stable ablation resistance of HfC 0.75 N 0.25 . Conversely, excessive nitrogen incorporation induces the formation of the Hf 7 O 8 N 4 phase with numerous defects and crack nucleation, ultimately deteriorating laser ablation resistance. These findings provide useful insights for the design and development of ultra-high temperature ceramics for applications in extreme environments. Download: Download high-res image (277KB) Download: Download full-size image
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DIAMOND AND RELATED MATERIALS
·
2026
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IF 5.2
Dong Sui,Zhanghan Shi,Zhirong Sun,Linqi Si,Wenwen Liu,Yanliang Yang,Yongsheng Zhang
With the merit of abundant resources, SiO 2 is emerging as a high-capacity and cost-effective anode for lithium-ion battery (LIB). Nevertheless, the inherently low conductivity and severe volume change of silica result in inferior rate capability and poor cycling life, which impede its practical applications. To overcome these shortcomings, designing novel nanostructures and coating with highly conductive carbon are two commonly used strategies to realize high-performance SiO 2 anodes. Herein, glucose-derived carbon coated SiO 2 nanotubes (SNTs@C) were designed and fabricated through a facile hydrothermal reaction and pyrolysis. Benefiting from the one-dimensional tubular structure and uniform carbon coating, SNTs@C can provide excellent transfer paths for electrons and ions, expose more active sites and accommodate the large volume variation. Therefore, the optimized SNTs@C could deliver a high specific capacity of 615 mAh g −1 , excellent rate capability of 220 mAh g −1 at 3 A g −1 , and superior cycling stability with a capacity of 400 mAh g −1 after 600 cycles. Our work offers a facile but feasible method to fabricate SiO 2 -based anode for LIB.
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ADVANCED FUNCTIONAL MATERIALS
·
2026
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IF 19.9
Siyu Guo,Xueting Ren,Xijiao Ren,Jinming He,Huocheng Yang,Wei Zhou,Menghuan Li,Lulu Wang,Yan Hu,Zhong Luo
The melanoma microenvironment is hallmarked by severe hypoxia and excessive regulatory T cells (Tregs), which significantly limits anti-melanoma efficacy of radiotherapy by impairing both its tumoricidal and immunostimulatory potential. Here, we report a supramolecular aptamer-engineered DNA di-tetrahedron nanoplatform (AEN) as a neoadjuvant treatment of melanoma radiotherapy, aiming to improve the radio-immunotherapeutic responses through dynamically remodeling the melanoma microenvironment. Specifically, DNA tetrahedra are separately loaded with vascular endothelial growth factor A inhibitor Thalidomide (Thal) and Treg-inhibitory drug Epirubicin (EPI) via DNA intercalation, followed by modification with plrogrammed death-ligand 1 (PD-L1) or cytotoxic T-lymphocyte-associated protein 4 (CTLA4) vascular endothelial growth factor A (VEGF-A)-binding aptamers and further conjugation with i-motif or chain-1 motifs to generate aptPD-L1-TDN@Thal and aptCTLA-4-TDN@EPI components, which eventually self-assemble into a di-tetrahedron through complementary binding between i-motif and chain-1. AENs dissociate into aptPD-L1-TDN@Thal and aptCTLA-4-TDN@EPI in acidic melanoma microenvironment, which are then taken up by PD-L1-overexpressing melanoma cells and CTLA4-overexpressing Tregs through ligand-mediated endocytosis. Thal inhibits tumor-intrinsic vascular endothelial growth factor A (VEGFA) signaling to normalize tumor vasculature for relieving hypoxia, while EPI inhibits Treg-intrinsic Foxp3-p65 signaling to abolish their immunosuppressive activity. The AEN treatment effectively remodels the melanoma microenvironment into a radiosensitive and immunosupportive state for enhancing the radio-immunotherapy response, providing an approach for melanoma radiotherapy in the clinic.
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SEPARATION AND PURIFICATION TECHNOLOGY
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2026
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IF 9.1
Shiyu Zhang,Zhiruo Li,Jia Tong,Xingxing Shi,Yue Xu,Lijuan Zhang,Haikuan Yuan,Yan Zhang,Jie Lu
A chiral metal-organic framework, [Zn( NCG )bpy] n (NCG = N-(4-aminobenzoyl)- L-glutamic acid; bpy = 4,4′-bipyridine), was meticulously designed and synthesized for the first time and thoroughly assessed for its extensive chiral recognition abilities. This MOF features an average pore size of 7.12 nm and is constructed from enantiopure N-(4-aminobenzoyl)-L-glutamic acid ligands, which provide functional sites for the highly enantioselective adsorption and separation of various chiral compounds. The chiral recognition ability of [Zn( NCG )bpy] n was initially tested with batch adsorption of ( R )- and ( S )-dropropizine enantiomers at various starting concentrations and solution pH levels. A dispersive solid-phase extraction (dSPE) strategy coupled with high-performance liquid chromatography (HPLC) was then employed to assess its competitive chiral resolution efficacy toward four structurally distinct racemates: ( R , S )-dropropizine, ( R , S )-tetramisole hydrochloride, (D,L)-phenylalanine, and (D,L)-aspartic acid. The [Zn( NCG )bpy] n exhibited remarkable enantioseparation capability toward smaller amino acid molecules, with an enantiomeric excess ( ee ) of 46.17 ± 1.39% and a separation factor of 2.72 ± 0.10 for (D,L)-phenylalanine in a single batch separation. X-ray photoelectron spectroscopy (XPS), combined with the Independent Gradient Model based on Hirshfeld partition (IGMH) isosurface analysis and binding energy computations, elucidated the underlying recognition mechanism at the atomic level. The results conclusively showed that chiral resolution is primarily regulated by non-covalent host-guest interactions.
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ENERGY & FUELS
·
2025
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IF 5.3
Xiu Chen,Ying Zhang,Haidong Li,Quan Shi,Suoqi Zhao,Linzhou Zhang
Vanadyl porphyrins, which have central metals in the form of cations, are liable to coordinate axially with basic ligands. In the presented paper, the interaction behaviors of vanadyl octaethylporphyrin (VOOEP) with different basic ligands, viz. amines and N-heterocycles (such as pyridine, morpholine, n-butylamine, triethylamine, diethylamine, azetidine, and pyrrolidine), have been studied in detail through ultraviolet–visible (UV–vis) spectroscopy, collision-induced dissociation (CID) combined with Orbitrap mass spectrometry (MS), and density functional theory (DFT). The axial coordination ability and binding preference of VOOEP and ligands, as well as the relative stability, binding energies, and absorption spectra of the VOOEP-ligand complexes, were fully characterized in this study. The complexes involved two types of binding forms: axial coordination bonding and hydrogen bonding. It was observed that the axial coordination between VOOEP and basic ligands resulted in a decrease in intensity and red-shift of the UV–vis Soret band compared to pure VOOEP. Moreover, the axial coordination is closely correlated to the basicity and steric hindrance of the ligands. The relative stability and binding energies of the complexes are positively related to the basicity of the ligands. Additionally, besides VOOEP-ligand complexes (1:1 adducts), VOOEP-VOOEP-ligand complexes (2:1 adducts) were also observed and studied. This work offers insights that may aid petrochemists in the separation, enrichment, or selective removal of vanadyl porphyrins from petroleum samples and the investigation of porphyrin-asphaltene association behavior.
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Nature Communications
·
2026
·
IF 15.7
Qingming Kong,Yu Tan,Kaiqiang Zhang,Haiyang Zhang,Tengyang Zhu,Xu Wang
Thermosetting polymers are widely used for their high mechanical performance and long-term structural reliability, but their permanent crosslinked networks prevent reprocessing and recycling, leading to persistent environmental challenges. Existing dynamic covalent and supramolecular strategies offer partial solutions, yet often suffer from performance loss after repeated recycling due to incomplete reversibility and the accumulation of defects. Here, we present a strategy for the decrosslinking and upcycling of post-service thermosets based on a dynamic polyurethane network containing hindered urea bonds (HUBs). The elastic network exhibits high mechanical strength, self-healing, and thermal reprocessability. Upon exposure to small-molecule amines, the HUBs undergo exchange reactions that enable controlled network disassembly, allowing the thermosets to be transformed into reprocessable thermoplastics. The decrosslinked derivatives facilitate high-value composites—toughening glass fiber matrices by 229% through interfacial reinforcement and achieving commercial-grade electromagnetic shielding (28.1 dB) via optimized carbon nanotube integration. This molecularly engineered decrosslinking-upcycling paradigm establishes a viable pathway for circular thermoset utilization, advancing sustainable polymer technologies. Dynamically cross-linked thermosets often show decreased performance after numerous reprocessing cycles, limiting their long-term recyclability. Here, the authors introduce dynamic hindered urea bonds into polyurethane, enabling its thermal-decrosslinking and offering an upcycling route.
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JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
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2026
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IF 4.9
Mingming Li,Suhong Fu,Jiaxin Chen,Xinxing Sun,Yang Chen,Lei Yang
High-quality wound healing is a primary clinical goal, yet it remains difficult to achieve reliably with current treatments. For this purpose, this study developed an ion-paired asiatic acid (AA) hydrogel specially for wound healing and systematically evaluated its pharmacodynamic efficacy both in vitro and in vivo. The formulation strategy involved screening organic amines as counter-ions using an ex vivo stratum corneum-removed skin model. Triethanolamine was identified as the optimal counterion, maximizing AA penetration into local tissue while minimizing systemic permeation via the formation of an ion-pair as confirmed by Nuclear Magnetic Resonance. The resulting hydrogel exhibited ideal properties for wound application, as characterized by its water vapor transmission rate, swelling ratio, degradability ratio, and water retention. In vitro , the hydrogel accelerated wound closure by stimulating cellular proliferation and migration, promoting vascular differentiation, and exhibiting selective antibacterial efficacy against S. aureus . In a rat full-thickness skin defect model, the hydrogel effectively facilitated scarless healing, which was mechanistically linked to collagen remodeling (indicated by a higher proportion of type III relative to type I collagen), suppression of TNF-α-mediated inflammation, and downregulation of TGF-β-driven fibrosis. Collectively, this work establishes a strategically designed ion-pair hydrogel system that coordinates key healing processes, offering a promising strategy for achieving reliable, high-quality wound regeneration.
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MICROCHEMICAL JOURNAL
·
2026
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IF 5.1
Li Zhang,Shanxia Jin,Xiaofeng Guo,Yi Yu,Ping Zhou
Lipids are structural components of biomembrane and also have multiple cellular functions. Lipids are difficult to be studied due to their great diversity. Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS) has played an important role in lipid analysis. However, the detection of specific lipids still suffers from challenges such as low selectivity and signal interference from other lipids, especially in complex biological samples. In this study, we have synthesized a series of N-alkyl-9-aminoacridines (N-alkyl-9AAs) with different alkyl chain lengths as the matrices for MALDI-MS analysis of phospholipids and created a unique strategy to distinguish phosphatidylethanolamine (PE) from other membrane phospholipids. A laser-induced ultrafast photochemical click reaction between N-alkyl-9AA and the amino group enabled to selectively tag PE species in source with an apparent yield up to 97%. Meanwhile the interference from phosphatidylcholine, most frequently encountered in MS analysis, was avoided. Among the N-alkyl-9AAs, C6-9AA exhibited the best performances and offered higher detection sensitivity for PEs in comparison to 9AA. This approach was successfully applied to the identification of PEs in Gram-positive and Gram-negative bacteria. This work not only provides a novel matrix for selective analysis of PE but also demonstrates a new way for fast screening of target biomolecules based on photochemical click reaction, avoiding tedious procedures for derivatization. In addition, it makes a valuable contribution to the understanding on the mechanism of MALDI.
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SCIENCE OF THE TOTAL ENVIRONMENT
·
2023
·
IF 9.8
Tianze Liu,Xiaobin Liao,Xinna Lin,Jing Yu,Huan Qi,Zhibin Jiang,Jing Zou,Qingsong Li
This study was to evaluate the feasibility of controlling carcinogenic nitrosodiethylamine (NDEA) formation from greenhouse gas adsorbent 3-diethylaminopropylamine (DEAPA) by pre-O 3 in subsequent chlorination/chloramination processes. The result indicated that the NDEA yields (0.4 %) during chlorination was 1.3 times of that during chloramination (0.3 %); pre-oxidation with 4 mg/L O 3 significantly cut down its formation; the reduction rates were up to 67.5 and 48.5 %, respectively. OH scavenger greatly augmented the final NDEA amount from 1.86 to 5.05 μg/L during ozonation , while its roles on subsequent processes differed with disinfection methods as well as O 3 (g) dosages. Most of co-existed substances inhibited NDEA generation, except NO 2 − , CO 3 2− and SO 4 2− , which slightly promoted during ozonation. Basing on Gaussian calculation, GC/MS and UPLC-Q-TOF-MS analysis, the influencing mechanisms of pre-O 3 on NDEA formation in subsequent disinfection processes were proposed. In addition, the calculated toxicity analysis as well as the whole toxicity was applied to evaluate the possibility of pre-O 3 on risk control.
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ACS Applied Nano Materials
·
2023
·
IF 5.9
Shushu Chao,Yiqiu Zhang,Shihong Cheng,Xinzhe Shao,Songlin Liu,Wenjuan Lu,Yanfeng Wang,Pingping Zhang,Qingqiang Yao
Based on the opportunities of ibuprofen administration innovation and challenges associated with the construction of transdermal drug delivery systems using medicated nanoparticles and electrospun nanofiber membranes, we developed a transdermal drug delivery system comprising ibuprofen-loaded ZnO nanoparticles/polyacrylonitrile electrospun nanofiber membranes (ZnO-ibuprofen/PAN), which was dual-stimulus responsive, wherein both pH and temperature triggered drug release. ZnO-ibuprofen nanoparticles with high drug loading capacity (17.7%) were prepared at room temperature by a one-step method involving 4,4′-((4-(4H-1,2,4-triazol-4-yl) phenyl) azanediyl)dibenzoic acid, Zn(NO3)2·6H2O, and ibuprofen, following which electrospinning was conducted to generate the ZnO-ibuprofen/PAN nanofibers. The transdermal drug release behavior of the ZnO-ibuprofen/PAN electrospun nanofiber membranes in the normal (pH = 7.4, 37 °C) and inflammatory (pH = 6.5, 42 °C) tissue environment exhibited increased drug release rate at higher ambient temperatures and decreased pH following 24 h of drug release. The cumulative drug release rate of ZnO-ibuprofen/PAN electrospun fibers through porcine skin under inflammatory conditions reached 71.35% ± 2.96% after 24 h, thereby demonstrating their favorable transdermal permeation behavior. The cytotoxicity assays revealed that the nanofibers possessed excellent biocompatibility. Thus, the dual stimulus-responsive ZnO-ibuprofen/PAN can be an effective transdermal drug delivery carrier.
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MOLECULES
·
2023
·Vol. 28
·期 6
·2444
·
IF 4.6
Yan Wang,Peng Dou,Xiaofeng You,Qing Liu,Zhaoyang Fei,Xian Chen,Zhuxiu Zhang,Jihai Tang,Mifen Cui,Xu Qiao
Resins have enormous potential in the removal of naphthenic acids (NAs) from transformer oil due to their rich porosity and high mechanical and diversified functionality, whereas their poor adsorption capacity limits application. In this work, the polystyrene–diethylamine resin (PS−DEA−x) was prepared by grafting diethylamine (DEA) onto chloromethylated polystyrene (PS−Cl) resin to efficiently adsorb cyclopentane carboxylic acid from transformer oil for the first time. The characterization analysis results indicated that amine contents were significantly enhanced with the increase in DEA. Particularly, resin with a molar ratio of 1:5 depending on chloromethyl to DEA (PS−DEA−5) exhibited the highest amine contents and efficient adsorption of cyclopentane carboxylic acid (static adsorption capacity up to 110.0 mg/g), which was about 5 times higher than that of the pristine PS−Cl. The thermodynamic and kinetic studies showed that the adsorption behaviors could be well fitted to the Langmuir isotherm equation and pseudo−second−order rate equation. Moreover, it was found that 1 g of the PS−DEA−5 can decontaminate about 760 mL transformer oil to meet reuse standards by a continuous stream, indicating its potential application in industry.Keywords:resin;diethylamine;chemical modification;cyclopentane carboxylic acid;transformer oil purification
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