Journal of Healthcare Engineering
·
2022
·Vol. 2022
·期 1
·2271937
·
IF 3.822
Xiangwen Yuan,Jiabin Zhang
Glaucoma is caused by excessive aqueous humor in the eye, resulting in a continuous or intermittent increase of intraocular pressure, which exceeds the tolerance of the eyeball and damages the optic nerve. Existing treatments for glaucoma do not work well or have significant side effects. Intraocular pressure signal is a very important physiological signal that needs real-time and accurate monitoring in glaucoma patients, especially in severe glaucoma patients. Therefore, long-term, real-time, and accurate monitoring of intraocular pressure is of great significance for the diagnosis and treatment of glaucoma patients. The use of wearable devices for real-time ocular diagnosis and treatment of glaucoma patients is an effective approach. However, the current commonly used intraocular pressure measurement and monitoring technology is difficult to meet the diagnosis and monitoring needs of glaucoma patients in terms of size, measurement accuracy, power consumption, and intelligence. Therefore, facing the needs of glaucoma disease treatment, this topic studies an implantable flexible intraocular pressure sensor for long-term continuous monitoring of intraocular pressure in glaucoma patients and mainly focuses on the working principle, structural design, process fabrication, measurement and control system, characterization, and performance test of the intraocular pressure sensor. It is of great significance for personalized and accurate treatment of glaucoma patients.
研究领域:
眼科
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生物医学工程
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传感器技术
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转化医学
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慢性病管理
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DOI
高影响因子
Nano Energy
·
2018
·
IF 13.12
Xuan Zhao,Zhuo Kang,Qingliang Liao,Zheng Zhang,Mingyuan Ma,Qian Zhang,Yue Zhang
In the Internet of things (IoT), motion sensor in the perceptual layer is at the forefront of the information collection, which plays a crucial role in the IoT. However, with a large number of commercial applications, several problems of motion sensor limit the development of IOT such as poor portability, poor environmental adaptability, and high energy consumption, etc. In this work, an ultralight, self-powered and self-adaptive motion sensor (UMS) is reported. Total mass of the UMS is less than 20 mg. Self-powered characteristic of the UMS is achieved based on the principle of triboelectric nanogenerator by using the coupling of triboelectrification and electrostatic induction as governed by the Maxwell's displacement current. Moreover, the UMS shows satisfactory self-adaptive performance of both temperature and humidity, less-sensitive to temperature in surroundings, from 15 ℃ to 60 ℃, and ambient humidity under 90% RH. Furthermore, sensing signals triggered by different motion behaviors, such as grasping, walking, stooping and so on, can be distinguished by the processor clearly, which can be applied to motion recognition and machine control. This work presents a novel UMS with characteristics of portability, energy conservation and environmental friendliness. The UMS shows broad prospect in perceptual layer application in IoT.
研究领域:
纳米能源
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传感器技术
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物联网
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微纳系统
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智能感知
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生物医学工程
·
可穿戴设备
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DOI
高影响因子
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
·
2017
·Vol. 45
·期 6
·830-836
·
IF 0.795
Hong-Cai ZHAO,Pu ZHANG,She-Hong LI,Hong-Xia LUO
A large area graphene platform electrode (GPE) was fabricated by transferring chemical vapor deposition (CVD) grown graphene on Cu foils onto polyethylene terephthalate (PET) substrates with the aid of polymethyl methacrylate (PMMA). Cobalt hexacyanoferrate (CoHCF) was electrodeposited on GPE by cyclic voltammetry. The morphology and electrochemical properties of CoHCF/GPE were studied by scanning electron microscope (SEM), electrochemical impedance spectroscopy (EIS) and the electrochemical measurements. The CoHCF/GPE showed favorable sensing effect toward H 2 O 2 . A novel non-enzyme H 2 O 2 sensor was constructed. Under the optimal experimental conditions, the proposed sensor responded to the addition of H 2 O 2 very quickly (about 2 s) with a wide linear rang (0.005–1.2 mM) and a low detection limit (7.1 nM). This sensor was easy to be fabricated and showed excellent stability and anti-interference ability.
研究领域:
电化学
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生物传感器
·
纳米材料
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分子诊断
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转化医学
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即时检测
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2024
·
IF 13.3
Yong Huang,Lida Xu,Qibin Zhuang,Xiong Zhou,Zhenjin Xu,Wei Xiao,Xin Liu,Qinnan Chen,Yang Zhao,Chao Wu,Daoheng Sun,Dezhi Wu
High-temperature heat flux sensors play a pivotal role in detecting the dynamic heat exchange processes of heating and cooling, in high-temperature environments. However, the detection of surface heat flux on curved parts operating at high temperatures remains a formidable challenge. Flexible thin-film heat flux sensors, while offering benefits such as conformal adhesion and excellent portability, are typically limited by low operational temperatures and narrow measurement ranges. This work proposes a high-temperature flexible heat flux sensor based on multi-layered high-temperature resistant ceramics nanofibre membranes that one layer worked as a substrate and the other two work as thermal resistance layers, and direct ink writing platinum sensitive elements with Wheatstone Bridge configuration. The prototype sensor is capable of quantifying heat flux reaching 1330 kW/m 2 and withstands temperature as high as 1200 °C. The sensor is bendable with resistance change only about 0.5 % even when the bending radius was larger than 10 mm. These extraordinary characteristics indicate that such methodology will offer a new way for the development of high-temperature thin-film flexible heat flux sensors, demonstrating considerable potential for applications in high-temperature environments.
研究领域:
传感器技术
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材料科学
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热物理学
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仪器仪表工程
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高温测量技术
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DOI
高影响因子
FOOD AND AGRICULTURAL IMMUNOLOGY
·
2019
·
IF 2.398
Fan He,Tingting Zou,Jinyi Yang,Hong Wang,Lihua Deng,Yuanxin Tian,Zhenlin Xu,Yuanming Sun,Hongtao Lei,Xuecai Tan,Yudong Shen
In this work, a rapid, convenient and sensitive Au nanoparticle-based immunochromatographic sensor (AuNPs-ICS) for simultaneous detection of various tadalafil adulterants in health food was established for the first time, based on one high affinity and broad-spectrum antibody through skeleton-specific hapten design according to the common structure of tadalafil drugs. This immunochromatographic sensor was developed by the polyclonal antibody conjugated with AuNPs and the IC50 was 10.04 ng mL−1 for tadalafil and 9.55, 11.46, 17.01 ng mL−1 for amino tadalafil, acetamino tadalafil and nortadalafil, respectively. The limit of detection results could be obtained visually by naked eyes for and computationally by the hand-held immunochromatography reader. The sensor could specially detect Tadalafil and its analogs within 10 min in health food samples, and the close correlation with UPLC-MS/MS method showed the sensor was accurate and reliable, which could apply to on site detection Tadalafil and its analogs rapidly and accurately.
研究领域:
分析化学
·
药物检测
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产品关联
DOI
高影响因子
CARBOHYDRATE POLYMERS
·
2019
·
IF 6.044
Jun Rao,Hui Gao,Ying Guan,Wen-qi Li,Qiang Liu
An effective and green method to incorporate graphene oxide into quaternized hemicelluloses to form a hemicelluloses based film was introduced in this study. Tight, homogeneous, and smooth surfaces of the film were obtained from the SEM image. Data on the mechanical properties of the films indicated that the hybrid films prepared from QH and GO (component of GO was 4.8%) exhibited a high tensile strength of 43.83 MPa. This finding suggested that addition of GO contributed to the desirable mechanical properties of the hybrid film. The hybrid films exhibited high sensitivity to humidity; they could be bent spontaneously under wet conditions within seconds and stretched under dry conditions. In addition, the results of DMA indicated that the storage modulus of the hybrid films had an order of magnitude change in value at different humidities. These characteristics show that films can be potentially used in bio-medicine, packaging materials, and humidity sensors.
研究领域:
材料科学
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生物医学工程
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环境科学
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产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2017
·
IF 5.401
Kai Liu,Ye Zhang,Ti Zhou,Xiaohe Liu,Bo Chen,Xin Wang,Xiaojun Zhao,Jianzhong Huo,Yajing Wang,Bolin Zhu
A novel multifunctional sensor based on the ‘privileged ligand’ salen scaffold conjugated with BODIPY was designed and synthesized. This conjugate displays a sequential recognition of Hg 2+ and I − with high selectivity and sensitivity via formation of three-component ensembles.These new approaches have been successfully applied for the detection of their corresponding targets in Haihe River with acceptable recovery.
研究领域:
分析化学
·
环境监测
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分子探针
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生物传感
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无机离子检测
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DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2018
·
IF 6.735
Xiangqian Li,Jiapei Gu,Zhan Zhou,Lufang Ma,Yiping Tang,Jinwei Gao,Qianming Wang
The generation of novel optical sensing structures through the lanthanide coordination has been a key scientific endeavor. The design of molecular indicator for chemical response is derived from the assembly of a polymeric-based ternary europium (III) complex system (Eu(NTA) 3 L/PVA (NTA = 4,4,4-trifluoro-1-(naphthalen-2-yl)butane-1,3-dione, L = 2-(4-(4-(allyloxy)phenyl)-6-(pyridin-2-yl)pyridin-2-yl)pyridine, PVA = poly(vinyl acetate)). The electrospinning technique has been employed to create a nanometer scale membrane and this functional film with ultrafine fibers (diameter of about 110 nm) exhibits intense red light at 618 nm under ultra-violet excitation of 340 nm. The luminescent signal transduction involves the interaction of hydrogen chloride (HCl) with the organic ligand. The strong acidity of the analyte induces dissociation of complex network and the evolution of emission from red to blue has been observed. The fabricated nanosensor demonstrates rapid response time (<2 s) and the detection limit has been calculated to be 3.0 ppm. This effective strategy for achieving lanthanide complex-encapsulated polymer fibers will contribute to the development of new intelligent photonic devices.
研究领域:
材料化学
·
分析化学
·
纳米科技
·
光子学
·
功能材料
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DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2022
·
IF 5.304
Xu Chu,Tao Chen,Yan Cao
This paper reports a simple, rapid and sensitive fluorescence sensor for the parallel determination of iron (III) (Fe 3+ ), terbium (III) (Tb 3+ ) and europium (III) (Eu 3+ ) ions using Carbon Dot (CD) serving as a fluorescence probe. The Carbon Dot (CD), which was synthesized via an acid-cutting method using anthracite coal as the carbon source, was found to have rich carboxyl and hydroxyl groups on its surface. The fluorescence of the as-prepared CD can be selectively quenched by the Fe 3+ ion via non-radiative electron-transfer, and furthermore, the as-prepared CD can also sensitize the luminescence of both Tb 3+ and Eu 3+ ions through the antenna effect and enhance the fluorescence of Tb 3+ and Eu 3+ by more than several orders of magnitude. Therefore, the as-prepared CD was applied as a fluorescence probe towards the parallel determination of Fe 3+ , Tb 3+ and Eu 3+ and exhibited detection limits in 0.019, 0.10 and 0.79 μM, respectively. The fluorescence quenching mechanism and energy transfer mechanism were also studied in details.
研究领域:
分析化学
·
环境监测
·
纳米材料
·
荧光探针
·
生物传感
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DOI
高影响因子
CHINESE CHEMICAL LETTERS
·
2019
·Vol. 31
·期 8
·2099-2102
·
IF 3.839
Xin Yu,Ding Wang,Yuqiu Wang,Ji Yan,Xianying Wang
In this work, the two-dimensional MoS 2 film was prepared by sulfuring the molybdenum atomic layer on SiO 2 /Si substrate. The reaction temperature, heating rate, holding time and carrier gas flow rate were investigated comprehensively. The quality of MoS 2 film was characterized by optical microscopy, atomic force microscopy, Raman and photoluminescence spectroscopy. The characterization results showed that the optimum synthesis parameters were heating rate of 25 °C/min, reaction temperature of 750 °C, holding time of 30 min and carrier gas velocity of 100 sccm. The MoS 2 gas sensor was fabricated and its gas sensing performance was tested. The test results indicated that the sensor had a good response to both reducing gas (NH 3 ) and oxidizing gas (NO 2 ) at room temperature. The sensitivity to 100 ppm of NO 2 was 31.3%, and the response/recovery times were 4 s and 5 s, respectively. In addition, the limit of detection could be as low as 1 ppm. This work helps us to develop low power and integrable room temperature NO 2 sensors.
研究领域:
材料科学
·
纳米科技
·
传感器技术
·
环境监测
·
半导体物理
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DOI
高影响因子
MACROMOLECULAR MATERIALS AND ENGINEERING
·
2018
·Vol. 303
·期 10
·1800339
·
IF 2.69
Zhandong Gu,Yichao Xu,Lie Chen,Ruochen Fang,Qinfeng Rong,Xu Jin,Lei Jiang,Mingjie Liu
Conductive hydrogels have attracted considerable attention due to their promising applications in a variety of fields. However, conductive hydrogels prepared by conventional strategies usually suffer from poor mechanical properties and low fatigue resistance. In this study, a synergistic strategy to fabricate macroporous conductive hydrogels (PC-hydrogels) by introducing macroporous structure to the hydrogels is reported. The polypyrrole can distribute uniformly in the hydrogel network, thus endowing the hydrogels with good electrical conductivity and outstanding fatigue resistance. Moreover, the combination of stiff polypyrrole and soft hydrogel network can enhance the mechanical properties of the hydrogel. As a result, the PC-hydrogels show negligible performance degradation after being compressed for more than 1200 cycles. Furthermore, the PC-hydrogels-based sensors can detect a variety of human motions with different intensities and ranges. The outstanding mechanical reliability and electrical conductivity make these PC-hydrogels suitable for application in areas of strain sensors and wearable devices.
研究领域:
生物材料
·
生物医学工程
·
柔性电子
·
纳米医学
·
组织工程
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DOI
高影响因子
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
·
2013
·
IF 2.672
Yinfeng Li,Lina Zou,Ge Song,Kunjing Li,Baoxian Ye
The electro-polymerization of l -Theanine was investigated for the first time on glassy carbon electrode and the polymeric conditions and mechanism were discussed in detail. Hereafter, a simple and sensitive electrochemical sensor based on the poly( l -Theanine) film was established for sophoridine sensing. The electrode process of sophoridine was then studied by cyclic voltammetry and its determination was achieved by amperometry . The results revealed that the poly( l -Theanine) membrane effectively decreased the oxidation potential of sophoridine and greatly increased its response current. And this sensor, fabricated easily and simply as well as very easy surface update, showed good response for sophoridine with a wide linear range from 1.0 × 10 −6 to 1.4 × 10 −4 mol L −1 and a low detection limit of 5 × 10 −7 mol L −1 . The application of proposed method in analysis of real sample was also evaluated with good performance. This work promoted the potential applications of amino acid materials in electrochemical sensors.
研究领域:
分析化学
·
电化学
·
药物分析
·
生物传感
·
分子诊断
·
药物代谢
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）