SOLAR ENERGY
·
2018
·
IF 4.374
Xiuli Wang,Xiaomin Cheng,Yuanyuan Li,Ge Li,Jun Xu
A self-assembly method is introduced to prepare composite phase change materials (PCMs) consisting of 1-octadecanol (OD) and graphene. The shape stability and thermal properties of 1-octadecanol/graphene composite PCMs with three-dimensional network structure are investigated. Graphene is dispersed evenly in OD matrix and the three-dimensional network structure is getting tighter with increasing ratio of graphene. OD is completely encapsulated at relatively low amount of graphene about 1.5 wt%. XRD and Raman results show that the combination between OD and graphene is physical adsorption. The 1-octadecanol/graphene (OG) composite phase change materials possess excellent shape stability, which can prevent the leakage of molten OD during phase transition. In addition, around 99.3% phase change enthalpy of pure OD is maintained by connected network structure of graphene while the melting and solidifying temperature merely have small fluctuations. The thermal conductivity of composite phase change material with 1.5 wt% graphene increases to 0.358 W/(m K), which is 1.5 times higher than that of pure OD. Furthermore, the porous network of graphene can delay the evaporation and thermal decomposition point of the composite phase change materials, thus extending the operating temperature of OD efficiently. This work provides a promising way to encapsulate low-temperature organic phase change materials with little carbon additives, and enhance the thermophysical properties of base materials simultaneously.
研究领域:
材料科学
·
能源工程
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JOURNAL OF CONTROLLED RELEASE
·
2026
·
IF 12.4
Yu Han,Guohua Ma,Kai Zhang,Runcai Xu,Ning Xin,Jingtong An,Ning Wang,Yantao Li
Lipid nanoparticles (LNPs) have emerged as a powerful nanoplatforms contributing to the success of mRNA vaccines. However, the rational design of lipid structures and the optimization of LNP composition, especially via metal-based adjuvants to boost extrahepatic delivery and immune responses, represent a promising yet technically challenging strategy. Herein, we developed a Zn(II)-adjuvanted imidazole-based LNP system that integrates rational lipid design with metal-coordinated self-assembly to achieve synergistic enhancement in delivery and immunogenicity. Initially, a library of 28 imidazole-based ionizable lipids was synthesized and screened, identifying A10–1 LNPs with a well-balanced lipid composition and high transfection efficiency. Furthermore, Zn 2+ coordination with the imidazole headgroup imparts Zn-A10–1 LNPs with enhanced structural stability and delivery performance, leading to improved cellular uptake, efficient endosomal escape, and preferential accumulation in the spleen. These attributes contributed to the robust activation of bone marrow-derived dendritic cells (BMDCs), induced memory T cell responses, and elevated proinflammatory cytokine secretion. In a melanoma model, vaccination with Zn-A10–1 LNPs markedly suppressed tumor progression and promoted the infiltration of OVA-specific CD8 + T cells. Overall, this study underscores the potential of Zn(II)-coordinated LNPs as effective nanoplatforms for extrahepatic mRNA vaccine delivery, offering a promising strategy for the mRNA-based vaccine design and immunotherapies.
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TRIBOLOGY INTERNATIONAL
·
2026
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IF 7.6
Lin Fan,Yongqiang Wang,Jian Qin,Changqing Liu,Xuemin Sun,Ming Zhang,Yijing Liang,Qiang Chen,Shuyan Yang,Yanyan Bai,Meirong Cai
The growing demand for reliable, long-lasting equipment performance has heightened the requirements for advanced lubrication solutions. Supramolecular gel lubricants not only mitigate lubricant creep but also enhance lubrication performance through precise molecular design. A novel phosphate ester-type gelator was designed through a simple synthesis route with low-cost raw material. The supramolecular gel lubricants exhibited dual responsiveness to temperature. Reversible sol-gel transitions were achieved by controlling the system within its specific transition temperature range. The gel state restricts the mobility of the lubricant, thereby facilitating its retention and practical development. In contrast, the sol state enhances the interface adsorption of the lubricant molecules, which in turn improves their lubrication performance. In addition, the supramolecular gels exhibited favorable viscoelastic properties, along with prominent shear-thinning behavior and efficient creep recovery performance. Importantly, phosphate-based supramolecular gels exhibit exceptional lubricating properties, including excellent anti-wear behavior, low friction coefficients, and high load-bearing capacities. The lubrication mechanism indicates that under boundary lubrication, the gel rapidly adsorbs onto surfaces. Under stress and thermal influence, it reacts with the substrate to continuously form a high-load-bearing reactive film that protects friction surfaces. In mixed lubrication or elastohydrodynamic lubrication, its unique rheological properties enable the formation of a thick fluid film that reduces wear and friction. These superior properties suggest that supramolecular gel lubricants could replace conventional oils and greases under certain working conditions.
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AICHE JOURNAL
·
2026
·
IF 4.4
Xuexue Dong,Benhuan Xu,Jian Tian,Bo Jiang,Yu Deng,Bin Chen,Yixin Li,Gen Li,Guowu Zhan
Selective deoxygenation of fatty acids to diesel-range alkanes without carbon-chain shortening is essential for sustainable biomass upgrading, but high selectivity remains challenging by competing decarbonylation/decarboxylation pathways. Here, a Re/In 2 O 3 featuring Re single atoms and ReO 3 clusters was synthesized for the hydrodeoxygenation of stearic acid. In contrast to In 2 O 3 , which primarily yields 1-octadecanol (93.1% selectivity) with minimal n-octadecane (1.2% selectivity), the optimized Re/In 2 O 3 catalyst achieves 100% selectivity diesel-range alkanes (>85% n-octadecane). Isotopic labeling, in situ spectroscopy, and kinetic analyses reveal Re-induced synergy: ReO 3 enhance H 2 dissociation, while Re single atoms promote bidentate adsorption of fatty acids, and oxygen vacancies in In 2 O 3 facilitate selective C–O bond cleavage. This multifunctional synergy suppresses C–C bond scission and significantly lowers the apparent activation energy for hydrodeoxygenation by 36.5 kJ·mol −1 . The catalyst exhibits broad applicability across diverse carboxylic acids, including unsaturated and aromatic substrates, underscoring its potential for efficient biomass utilization.
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ACS Applied Nano Materials
·
2026
·
IF 5.8
Congkai Guo,Yao Liu,Xiaoyu Yao,Wenjuan Xia,Shaoyang Xu,Lianjun Xiao,Guohua Wu,Yaohong Zhang
Low-dimensional tungsten oxide (WOx) nanomaterials, characterized by large active surface areas and electrochemical activity, have recently emerged as a hot research area in the field of electrochromism. In oil-phase synthesis, long-chain ligands are commonly employed for synthesizing and stabilizing colloidal WOx quantum dots (QDs) as well as preventing QDs aggregation, but they form a dense insulating coating that impedes charge transfer between QDs which must be removed during the fabrication of solid films, significantly affecting their electrochromic performance. In this work, we innovatively adopted a solid-state ligand exchange method to employ short-chain organic molecular ligands with thiol functional groups such as 1,2-ethanediol (EDT) and 3-mercaptopropanoic acid (MPA), along with halide ion ligands such as tetrabutylammonium iodide (TBAI) and cetyltrimethylammonium bromide (CTAB), to replace the original oleic acid ligands on the surface of colloidal WOx QDs which was synthesized by a solvothermal method, thereby preparing WOx QD solid films. Subsequently, the effects of different ligands on the electrical and electrochromic properties of the WOx QD films were systematically investigated. Results revealed that EDT-modified WOx QD films exhibited the highest optical modulation (80.3% at 750 nm) and fastest response times (tc/tb = 5.49/3.50 s) among other ligands-modified WOx QD films due to its lower defect state and higher ion diffusion rate, demonstrating outstanding electrochromic performance. Notably, the WOx QD films prepared by this method require no annealing treatment, supporting the development of highly efficient, flexible inorganic electrochromic devices.
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JOM
·
2026
·
IF 2.3
Xiang Zhe,Xu Chengjin,Yu Haiyin,Wang Zhimei,Sun Guoxin,Cui Yu,Peng Xiujing
Titanium white waste acid contains economically recoverable concentrations of scandium (25 mg/L); however, the high acid content and presence of multiple impurity ions present significant challenges for scandium separation. In this study, a novel monoalkyl phosphate extractant, PC68, consisting of 1-hexadecyl phosphate and 1-octadecyl phosphate, was synthesized. The effects of extraction time, sulfuric acid concentration, and temperature on scandium extraction were systematically investigated using a simulated titanium white waste acid solution. The results demonstrated that equilibrium was reached within 50 min at 298 K, and that the extraction efficiency of scandium with 0.1 mol/L PC68 was 99%. Analytical techniques, including the Equimolar Series Method, FT-IR, and XPS, confirmed that PC68 extracts scandium through coordination with P-O − and P=O groups. The separation performance of scandium from titanium white waste acid was evaluated, yielding high separation factors of 1093 for Sc/Fe and 733 for Sc/Mn, which demonstrates excellent separation efficiency. The addition of 1% H 2 O 2 followed by three-stage countercurrent extraction enabled effective separation of scandium and titanium. These results provide new insights and practical approaches for scandium separation from titanium white waste acid.
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Materials Today Communications
·
2025
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IF 4.5
Zitong Chen,Tao Hu,Li Li,Wenhui Yuan
Traditional thermal insulation materials can slow down the transfer of heat while having the drawback of being vulnerable to the environmental factors and low energy utilization efficiency. In this work, the 1-octadecanol (OD) phase change aerogels based on polyvinyl alcohol (PVA) were fabricated through simple freezing-thawing cycles and lyophilization. The prepared PVA/GX/OD-4 aerogel exhibits a high phase change enthalpy up to 149.5 J/g and a thermal conductivity as low as 0.0795 W·m −1 ·K −1 , showing superior hot-water heat-preservation performance compared with ceramic fiber papers. Meanwhile, the aerogel demonstrates exceptional mechanical properties, achieving a compressive strength of 9.72 MPa at 80 % strain with a low density of only 0.2108 g/cm 3 and displays thermal reliability during continuous heating-cooling repetition processes, with only a 1.8 % decrease in heat value after 100 thermal cycles. This work offers a simple and efficient strategy for the design of thermal insulation materials with energy storage capabilities which have significant potential for practical applications within the realm of thermal insulation.
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CHEMICAL ENGINEERING JOURNAL
·
2026
·
IF 12.5
Lei Tan,Wei Tan,Yin Tian,Guixiang Song,Ying Chang,Ping Li,Yuanlin Ren
Cellulose aerogels are widely regarded as an ideal thermal insulation material. However, the production equipment of aerogels, such as supercritical dryers or lyophilisers, requires extreme operating conditions. The present study has developed a novel method that combines thermally induced phase separation with heterogeneous ice nucleation to prepare cellulose aerogels via an ambient drying process. This methodology can be applied to a variety of manufacturing technologies in order to produce fibers (1D), films (2D) and complex structures (3D). The resulting cellulose aerogels fibers exhibit an excellent tensile strength of 25.63 MPa, a high porosity of 91.2%, and a strain value of 81.9%. This represents a substantial enhancement over conventional cellulose aerogel fibers (approximately 2%). It demonstrated that the thermal insulation performance remained stable even after the material was subjected to washing and dyeing processes. This preparation strategy offers a plethora of possibilities for the development of multifunctional cellulose aerogel fibers, cellulose aerogel films, and three-dimensional cellulose aerogel structures.
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RSC Advances
·
2023
·Vol. 13
·期 7
·4542-4552
·
IF 3.9
Bin Yu,Huicong Liu,Haining Chen,Weiping Li,Liqun Zhu,Weitao Liang
Hydrophobic coatings have attracted extensive research due to their broad application prospects. However, hydrophobic coatings in practical applications are often limited by their insufficient stability and are difficult to be applied on a large scale. In this regard, wear and heat resistance are key aspects that must be considered. In this paper, a method for preparing a robust hydrophobic coating with modified ZrO2 particles as the core component and modified acrylic resin is proposed. First, γ-aminopropyltriethoxysilane (APTES) was used to silanize ZrO2 to obtain Si–ZrO2 nanoparticles, which were grafted with amino groups. Then, the nanoparticles reacted with isocyanates to be grafted with hydrophobic groups. A simple spray method was developed to deposit a hydrophobic (141.8°) coating using the mixture containing the modified nanoparticles and non-fluorinated water-based silicon-modified acrylic resin (WSAR) that was prepared by free radical polymerization. The obtained coating exhibited a rough surface and the particles and resin were closely combined. Compared with pure resin coating, the composite coating exhibited 150% enhancement in wear resistance and it could wear 45 meters at a pressure of 20 kPa. Moreover, the coating could maintain the hydrophobic property even when it lost 70% quality or after it was heated at 390 °C. The thermogravimetric results showed that the temperature could reach 400 °C before the quality of the fluorine-free coating dropped to 90%. In addition, the coating could easily take away graphite or silicon carbide powder under the impact of water droplets, showing excellent self-cleaning performance.
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Metabolic Engineering Communications
·
2022
·
IF 0
Yushi Liu,Wan-Qiu Liu,Shuhui Huang,Huiling Xu,Haofan Lu,Changzhu Wu,Jian Li
Fatty acid-derived products such as alkanes, fatty aldehydes, and fatty alcohols have many applications in the chemical industry. These products are predominately produced from fossil resources, but their production processes are often not environmentally friendly. While microbes like Escherichia coli have been engineered to convert fatty acids to corresponding products, the design and optimization of metabolic pathways in cells for high productivity is challenging due to low mass transfer, heavy metabolic burden, and intermediate/product toxicity. Here, we describe an E. coli -based cell-free protein synthesis (CFPS) platform for in vitro conversion of long-chain fatty acids to value-added chemicals with product selectivity, which can also avoid the above issues when using microbial production systems. We achieve the selective biotransformation by cell-free expression of different enzymes and the use of different conditions (e.g., light and heating) to drive the biocatalysis toward different final products. Specifically, in response to blue light, cell-free expressed fatty acid photodecarboxylase (CvFAP, a photoenzyme) was able to convert fatty acids to alkanes with approximately 90% conversion. When the expressed enzyme was switched to carboxylic acid reductase (CAR), fatty acids were reduced to corresponding fatty aldehydes, which, however, could be further reduced to fatty alcohols by endogenous reductases in the cell-free system. By using a thermostable CAR and a heating treatment, the endogenous reductases were deactivated and fatty aldehydes could be selectively accumulated (>97% in the product mixture) without over-reduction to alcohols. Overall, our cell-free platform provides a new strategy to convert fatty acids to valuable chemicals with notable properties of operation flexibility, reaction controllability, and product selectivity.
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Pharmaceutics
·
2023
·Vol. 15
·期 1
·262
·
IF 5.4
Yuting Liu,Xinhui Wang,Zhe Wang,Rui Liao,Qian Qiu,Yuequan Wang,Cong Luo
Cabazitaxel (CTX) has distinct therapeutic merits for advanced and metastatic cancer. However, the present clinical formulation (Jevtana®) has several defects, especially for undesirable tumor-targeting and serious side effects, greatly limiting the therapeutic efficacy. Small-molecule prodrug-based nanoassemblies integrate the advantages of both prodrug strategy and nanotechnology, emerging as a promising treatment modality. Herein, disulfide bonds with different lengths were employed as linkages to elaborately synthesize three redox-sensitive stearyl alcohol (SAT)-CTX prodrug-based nanoassemblies (SAC NPs, SBC NPs and SGC NPs) for seeking optimal chemotherapeutical treatment. All the prodrug-based nanoassemblies exhibited impressive drug-loading efficiency, superior self-assembly capability and excellent colloidal stability. Interestingly, the drug release behaviors of three prodrug-nanoassemblies in the same reductive environment were different owing to tiny changes in the carbon chain length of disulfide bonds, resulting in disparate cytotoxicity effects, pharmacokinetic outcomes and in vivo antitumor efficacies. Among them, SAC NPs displayed rapid drug release, excellent cytotoxicity, long blood circulation and enhanced tumor accumulation, thus showing strong tumor inhibition in the 4T1-bearing mouse model. Our study shed light on the vital role of connecting bonds in designing high-efficiency, low-toxicity prodrug nanoassemblies.Keywords:cabazitaxel;disulfide bond;prodrug nanoassemblies;reduction-responsive;cancer therapy
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Journal of Materials Chemistry B
·
2022
·Vol. 10
·期 48
·10027-10041
·
IF 7.571
Jieqiong Cen,Yuqin Huang,Jie Liu,Yanan Liu
Reactive oxygen species (ROS) have become an effective “weapon” for cancer therapy due to their strong oxidation and high anti-tumor activity. Photodynamic therapy (PDT) is one of the classical methods to induce reactive oxygen species. Therefore, an ultraminiature palladium ruthenium alloy (sPdRu) and Ru(II) were combined with thermally responsive phase change materials (PCMs). Polypyridyl-complex (RCE) co-encapsulation was performed to obtain thermally responsive nanoparticles (PdRu-RCE@PCMNPs) for multimodal synergistic anti-breast cancer therapy. On the one hand, the thermosensitive PCM protective layer can realize the slow release of sPdRu, and then catalyze the production of oxygen from tumor endogenous H2O2 to perform RCE-mediated PDT. At the same time, sPdRu further increased ROS levels through peroxidase (POD) activity. On the other hand, sPdRu has high photothermal conversion efficiency and can be effectively used for photothermal therapy and photodynamic therapy. Importantly, PdRu-RCE@PCM NPs not only can effectively inhibit primary tumor growth, but also can inhibit tumor metastasis. In addition, due to the effective accumulation of sPdRu and RCE, PdRu-RCE@PCM NPs also show excellent fluorescence and photothermal imaging capabilities of tumors, which can be used for tumor tracing and evaluation of treatment. Accordingly, PdRu-RCE@PCM NPs are useful in treating primary tumors and inhibiting tumor metastasis.
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