MICROCHEMICAL JOURNAL
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2026
·
IF 5.1
Yidan Zhang,Yuhua Lai,Yifei Ma,Lin Ge,Jinhua Liu
Since excess histamine (His) in seafood poses a significant health threat, the development of intelligent, on-site, and visual multimodal methods for detecting fish freshness has attracted widespread attention. In this study, we developed a Lewis base-induced paper-based chip coupled with smartphone RGB (Red Green Blue) recognition for the real-time colorimetric/fluorescent dual-mode detection of His in fish meat. The sensing mechanism was based on the catalytic role of His in rapidly forming a green fluorescent compound (GFC) from dopamine and 3-ethylamino-4-methylphenol. Interestingly, the introduction of 1% Tween (TW) 80 was found to significantly enhance the fluorescence signal and real-time stability of the system, achieving an exceptional detection limit of 16.67 nM for His. By immobilizing the GFC probe on Whatman 1 filter paper, a paper-based test strip for His was further developed. His quantification is achieved through RGB analysis with a smartphone, allowing visual and real-time assessment of fish meat freshness directly in the field. The developed sensor exhibits outstanding selectivity, stability, and sensitivity, and has been successfully applied to monitor His levels in fish meat samples (crucian, saury and golden pomfret) over time, providing a reliable means to prevent His poisoning. Therefore, this work presents a robust, low-cost, and user-friendly point-of-care testing platform that holds significant potential for applications in intelligent food monitoring and environmental sensing.
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ADVANCED ENGINEERING MATERIALS
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2026
·
IF 3.6
Jiashuo Sun,Jianyu Jiang,Junwen Che,Zhiqiang Zhang,Yongji Wang,Hong Zhang,Yue Yu
Energy shortage and water scarcity are global challenges, and integrating thermal energy storage with seawater desalination is an effective approach to address these issues. In this study, a phase-change thermal management film (PGPF) with excellent photothermal conversion capability was fabricated via a blending and doping process, combining double-network phase-change microgels (PSP), graphene oxide (GO), and poly(vinyl alcohol) (PVA). Inspired by the bioinspired flexible and strong adhesion mechanism of octopus tentacles, PSP was prepared and uniformly “welded” within the material through hydrogen bonding among PSP, GO, and PVA, forming a multinetwork structure. This design significantly enhances the mechanical properties of PGPF in saline environments (up to 130 MPa) and its self-healing ability, extending its service life during seawater desalination. PGPF efficiently converts solar energy into heat, exhibiting high photothermal conversion efficiency, enabling rapid temperature rise to high levels, and achieving efficient thermal evaporation. Under xenon lamp illumination simulating sunlight, the PGPF temperature quickly reaches 162 °C, demonstrating excellent photothermal performance, with an evaporation rate as high as 3.18 kg·m −2 ·h −1 . The material’s outstanding phase-change behavior and thermal stability indicate its promising potential for solar-driven seawater desalination applications.
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ACS Biomaterials Science & Engineering
·
2026
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IF 6
Cong Cao,Rou Li,Yanning Guo,Wei Ji,Yuqing Wang,Yingjie Yu,Shiqing Xu,Chunyu Li,Baohua Xu,Qing Cai,Jing Li
Periodontal bone destruction caused by periodontitis, surgery, or trauma results in loss of periodontal ligament attachment, which in turn leads to tooth mobility and tooth loss. Complete periodontal bone reconstruction remains challenging. Periodontal ligament mesenchymal stem cells (PDLSCs) are a crucial cellular resource for regenerating and repairing periodontal bone defects. As a cell-free therapeutic approach, exosomes (Exos) derived from PDLSCs represent a promising and effective cell-free therapeutic strategy for inducing neo-bone growth. Due to the electrophysiological features of native bone, this study proposed the use of a piezoelectric fibrous membrane as the delivery carrier for Exos in guided tissue/bone regeneration therapy, synergistically promoting periodontal bone regeneration. The membrane was composed of poly(l-lactide)/gelatin, fabricated via electrospinning, and coated with polydopamine for Exos loading and sustained release. The piezoelectricity of the membrane came from the poly(l-lactide) after polarization. The material electroactivity and the bioactive Exos combinedly created a microenvironment conducive to cell recruitment, proliferation, angiogenic and osteogenic differentiation. In rat periodontal bone defect models, piezoelectric membranes functionalized with PDLSC-Exos significantly enhanced bone regeneration compared to membranes lacking Exos or piezoelectric properties. Collectively, this study provided valuable new insights to design biomimetic membranes with enhanced angiogenesis and osteogenesis properties for vascularized periodontal bone regeneration and other applications.
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PubMed
高影响因子
MOLECULES
·
2025
·Vol. 30
·期 12
·2543
·
IF 4.6
Qiaoling Liu,Xiaole Chen,Menghan Wu,Weihao Wang,Yinru Lin,Zilong Chen,Shuhan Yang,Yuhui Zheng,Qianming Wang
The primary challenge associated with stainless steel in fuel cell operation is its susceptibility to corrosion, which leads to increased contact resistance and subsequent degradation of electrochemical performance. In general, the protective layers have been loaded onto the metal surface by widely used traditional techniques such as physical vapor deposition (PVD), or cathode arc ion plating. However, the above sputtering and evaporation ways require a high-vacuum condition, complicated experimental setups, higher costs, and an elevated temperature. Therefore, herein the achievement for uniform coatings over a large surface area has been realized by using a cost-effective strategy through a complete wet chemical process. The synergistic regulation of two conductive components and a plastic additive has been employed together with the entrapment of a surfactant to optimize the microstructure of the coating surface. The assembly of layered graphite and a polystyrene sphere could maintain both the high corrosion resistance feature and excellent electrical conductivity. In particular, the intrinsic vacant space in the above physical barriers has been filled with fine powders of indium tin oxide (ITO) due to its small size, and the interconnected conductive network with vertical/horizontal directions would be formed. All the key technical targets based on the U.S. Department of Energy (DOE) have been achieved under the simulated operating environments of a proton exchange membrane fuel cell. The corrosion current density has been measured as low as 0.52 μA/cm2(for the sample of graphite/mixed layer) over the applied potentials from −0.6 V to 1.2 V and its protective efficiency is evaluated to be 99.8%. The interfacial contact resistance between the sample and the carbon paper is much less than 10 mΩ·cm2(3.4 mΩ·cm2) under a contact pressure of 165 N/cm2. The wettability has been investigated and its contact angle has been evolved from 48° (uncoated sample) to even 110°, providing superior hydrophobicity to prevent water penetration. Such an innovative approach opens up new possibilities for improving the durability and reducing the costs of carbon-based coatings.
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Arabian Journal of Chemistry
·
2023
·
IF 6
Baimei Dai,Peng Xu,Mingbiao Xu,Qisheng Jiang,Qinglin Liu,Siwei Wang
It is difficult to seal oil-based drilling fluids in the large pore and micro-fracture formation, and there are few suitable materials for the oil phase with good sealing ability at present. In order to solve the problem of the lack of sealing ability of oil-based drilling fluids, acrylamide, 2-acrylamido-2-methylpropane sulfonic acid, and acryloyl morpholine were used as monomers, N' N -methylenebisacrylamide was used as a cross-linking agent, Span-80 and Tween-60 were used as emulsifiers, and 2,2′-azobis(2-methylpropionamidine) dihydrochloride was used as an initiator. Polymer microsphere emulsion OPME was synthesized by inverse emulsion polymerization. The structure of polymer microspheres was characterized by infrared spectroscopy, scanning electron microscopy, electron microscopy, H NMR, laser particle size analysis and thermogravimetric analysis. The optimal synthesis conditions were determined by the control variable method: the monomer ratio of acrylamide, 2-acrylamido-2-methylpropane sulfonic acid, and acryloyl morpholine was 45:20:15, the amount of emulsifier was 8%, and the reaction temperature was 55℃. The synthetic polymer microspheres were added to the oil-based drilling fluids to perform filtration and loss plugging at atmospheric pressure and high-temperature and high-pressure, as well as pore and artificial fracture core plugging evaluation. The evaluation results show that the permeability reduction rate of pore core can reach 82%, and that of fracture core can reach 100% by adding polymer microspheres with 3% dosage. Finally, the pressure transmission experiment proves that the addition of polymer microspheres can slow the pressure transmission and filtrate intrusion, and enhance the stability of wellbore. Therefore, polymer microspheres are a micron-level plugging agent with good compatibility and high performance with oil-based drilling fluids, and the 3% dosage can better seal the formation of large pores and micro-fractures, which has a good potential for field application.
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COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
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2022
·
IF 5.518
Dege Li,Jianchao Li,Kaixin Wang,Guodong Yang,Yi Cao,Bingfang Huang,Xinlei Wu,Qiang Sun,Chi Ma,Lilong Zhao,Peng Liu,Yonghong Liu,Yanzhen Zhang
Diverse functional alginate fibers have played irreplaceable roles in life science, precision measurement, etc., drawing considerable attention from numerous researchers. However, further application of multifunctional fibers is greatly restricted by the preparation efficiency and the flexibility of equipment. Herein, modified anti-Rayleigh-Plateau-Instability sodium alginate solution filament and homemade piezoelectric ejector have been prepared to develop an efficient dry-jet wet spinning and encapsulating system for preparing functional fibers. This method has two working modes, which can readily realize the fabrication of conventional hollow fibers or fibers wrapping super large bubbles and functionalized fibers encapsulating reagents with on-demand size (ranging from 1 to 100 µm) and interval distance (ranging from several microns to a few centimeters) with excellent flexibility. Furthermore, the fiber size can be facilely tuned by regulating the flow rate and the rolling speed, up to 1 m s −1 , higher than all the wet spinning techniques ever reported. Functional reagents with different sizes and shapes have been encapsulated in fibers to verify the feasibility and practicality of this approach, demonstrating the potential for further applications in drug delivery, even cell encapsulation and culture.
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Bioactive Materials
·
2022
·
IF 16.874
Yike Gao,Zuoying Yuan,Xiaojing Yuan,Zhuo Wan,Yingjie Yu,Qi Zhan,Yuming Zhao,Jianmin Han,Jianyong Huang,Chunyang Xiong,Qing Cai
Exosomes derived from mesenchymal stem cells (MSCs) have demonstrated regenerative potential for cell-free bone tissue engineering, nevertheless, certain challenges, including the confined therapeutic potency of exosomes and ineffective delivery method, are still persisted. Here, we confirmed that hypoxic precondition could induce enhanced secretion of exosomes from stem cells from human exfoliated deciduous teeth (SHEDs) via comprehensive proteomics analysis, and the corresponding hypoxic exosomes (H-Exo) exhibited superior potential in promoting cellular angiogenesis and osteogenesis via the significant up-regulation in focal adhesion, VEGF signaling pathway, and thyroid hormone synthesis. Then, we developed a platform technology enabling the effective delivery of hypoxic exosomes with sustained release kinetics to irregular-shaped bone defects via injection. This platform is based on a simple adsorbing technique, where exosomes are adsorbed onto the surface of injectable porous poly(lactide-co-glycolide) (PLGA) microspheres with bioinspired polydopamine (PDA) coating (PMS-PDA microspheres). The PMS-PDA microspheres could effectively adsorb exosomes, show sustained release of H-Exo for 21 days with high bioactivity, and induce vascularized bone regeneration in 5-mm rat calvarial defect. These findings indicate that the hypoxic precondition and PMS-PDA porous microsphere-based exosome delivery are efficient in inducing tissue regeneration, hence facilitating the clinical translation of exosome-based therapy.
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ACS Photonics
·
2022
·
IF 7.077
Hongwei Yu,Hao Zhu,Mengxin Xu,Jiaming Zhang,Haiwei Feng,Letian Zhang,Shihao Liu,Wenfa Xie
Flexible displays are essential to provide information in real time for human–machine interactions. As a next-generation display technology, quantum-dot light-emitting diodes (QLEDs) are potentially serving as key components for flexible displays. However, it is still challenging for QLEDs to simultaneously achieve flexibility, large-scale production, and high efficiencies. To this end, a strategy is proposed here by combining a top-emitting structure, optical microcavity optimization, and large-scale film preparation. A top-emitting microcavity with semitransparent and reflective metals is designed to achieve flexibility, efficient carrier injection, and high light extraction efficiency. Precision manufacturing of large-area QLEDs with the designed top-emitting microcavity is achieved by combining surfactant-assisted blade-coating and vacuum thermal evaporation processes. With this strategy, a large-area flexible QLED with an active area of 400 mm2 and a maximum external quantum efficiency of 21.8% is developed. This strategy provides a promising approach toward the development of flexible displays with the demonstration of a 1.3 in. passive-matrix flexible QLED display of 19 by 19 pixels.
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JOURNAL OF HAZARDOUS MATERIALS
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2022
·
IF 14.224
Jian Zhang,Siyan Zhan,Lu-Bin Zhong,Ximo Wang,Zumin Qiu,Yu-Ming Zheng
With rapid urbanization, microplastics and natural organic matters (NOMs) are ubiquitous in aquatic environment, and microplastics could act as carriers for organic matters in the aqueous solution and may pose a potential risk. In this study, the adsorption behaviors and mechanism of typical NOM, humic acid (HA), on polyvinyl chloride (PVC) and polystyrene (PS) microplastics were investigated. Various influence factors such as solution pH, ions species and concentrations, particle size, and coexisting surfactants were studied. The results suggested that HA adsorption onto PVC and PS was low pH-dependent, and ion species and concentrations have a significant impact on the adsorption capacity. In addition, the particle size of PVC and PS microplastics exhibited a significant correlation with HA adsorption, and the adsorption process was influenced by the surfactant species and concentrations. Moreover, the adsorption behaviors of HA in different real water environments were tested, and UV aging exhibited the opposite effects on adsorption capacity of PVC and PS. Furthermore, the adsorption mechanisms of HA onto PVC and PS were explored, indicating halogen bonding, hydrogen bonding, and π–π interaction play important roles in the adsorption process.
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Micro & Nano Letters
·
2022
·Vol. 17
·期 2
·42-48
·
IF 0.98
Liya Zeng,Zhe Wang
The chemical compositions of Ginkgo biloba exocarp extracts (GBEE) and leaf extracts are similar, however, studies describing the development of GBEE biopesticides are few. In this study, the authors investigated the preparation of GBEE nanoemulsionand and characterized by transmittance, physical stability, droplet size and size distribution for the first time. Insecticidal activity and lipophilicity screening of four different solvents indicated ethyl acetate was satisfactory. Based on dispersibility, centrifugation, heating-cooling cycle, cloud point and long-term stability experiments, two formulations (ethyl acetate/Tween 40-Span 60 (9:1)/water and ethyl acetate/Tween 60-Span 60 (9:1)/water) were optimum to formulate nanoemulsions. However, the smallest droplet size and size distribution (10.93 ± 0.16 nm, PDI = 0.15 ± 0.01) was obtained using the Tween 60/Span 60 combination. The insecticidal activity of GBEE nanoemulsion was evaluated against the third instar larvae of Plutella xylostella . Lethal concentration (LC 50 ) values of the optimized nanoemulsion were 127.38 mg/L at 12 h and 72.80 mg/L at 24 h, respectively. This indicated that GBEE nanoemulsion had higher insecticidal activity than the GBEE. The results proposed that the GBEE nanoemulsion is a potential and effective natural alternative for the management of P. xylostella .
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MOLECULES
·
2021
·Vol. 26
·期 24
·7464
·
IF 4.412
Liya Zeng,Yongchang Liu,Zhihui Yuan,Zhe Wang
The purpose of this work was to evaluate the possibility of adding tea saponin (TS) to reduce the synthetic surfactant concentration, and maintain or improve the shelf stability of nanoemulsions. TheZanthoxylum bungeanumessential oil (2.5 wt%) loaded oil-in-water nanoemulsions were co-stabilized by Tween 40 (0.5–2.5 wt%) and TS (0.1–5 wt%). A combination of several analytical techniques, such as dynamic laser scattering, interfacial tension, zeta potential, and transmission electron microscope, were used for the characterization of nanoemulsions. Low levels of TS (0.1–0.5 wt%) with Tween 40 had significant effects on the emulsification, and a nanoemulsion with the smallest droplet diameter of 89.63 ± 0.67 nm was obtained. However, in the presence of high TS concentration (0.5–5 wt%), micelles generated by the non-adsorbed surfactants in the aqueous lead to droplets growth. In addition, the combinations of Tween 40 and TS at the high level (>3.5 wt%) exerted a synergistic effect on stabilizing the nanoemulsions and preventing both Ostwald ripening and coalescence. The negative charged TS endowed the droplets with electrostatic repulsion and steric hinderance appeared to prevent flocculation and coalescence. These results would provide a potential application of natural TS in the preparation and stabilization of nanoemulsions containing essential oil.Keywords:tea saponin;Zanthoxylum bungeanum;biosurfactants;Ostwald ripening;electrostatic repulsion
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JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
·
2021
·Vol. 109
·期 12
·2580-2596
·
IF 4.396
Yiqian Huang,Zhiyun Du,Tianyi Zheng,Wei Jing,Huanhuan Liu,Xue Liu,Jianping Mao,Xu Zhang,Qing Cai,Dafu Chen,Xiaoping Yang
Many osteoconductive and osteoinductive scaffolds have been developed for promoting bone regeneration; however, failures would occur in osteogenesis when the defect area is significantly infected while the biomaterials have no antibacterial performances. Herein, a kind of multipurpose PATGP@PDA + Ag microspheres was prepared via emulsion method by using a conductive aniline tetramer (AT) substituted polyphosphazene (PATGP), followed by polydopamine (PDA) modification and silver nanoparticles (AgNPs) loading. The PATGP@PDA + Ag microspheres demonstrated a strong antibacterial activity against Staphylococcus aureus both in vitro and in vivo, while showing no cytotoxicity at an optimized AgNPs loading amount. Due to the electron-donor structure of the AT moieties, the PATGP@PDA + Ag microspheres displayed antioxidant capacities to scavenge reactive oxygen species (ROS). Due to their phosphorus-rich feature, the PATGP@PDA + Ag microspheres favored the osteogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). As controls, nonconductive microspheres (PAGP@PDA, PAGP@PDA + Ag) were prepared similarly by using poly[(ethylalanine)(ethylglycyl)]phosphazene (PAGP). By co-implanting these microspheres with S. aureus into rat calvarial defects, among them, it was determined that the PATGP@PDA + Ag microspheres achieved the most abundant neo-bone formation, benefiting from their antibacterial, antioxidant and osteogenic activities. These results revealed that AgNPs loaded scaffolds made of conductive polyphosphazenes were promising for the regeneration of infected bone defects.
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危险品化学品经营许可证（带存储）