INTERNATIONAL JOURNAL OF FOOD PROPERTIES
·
2026
·
IF 3.9
Nian Cao,Yubo Yang,Xiaoling Xiong,Bohan Zhang,Ping Xiang,Fan Yang
This pioneering study investigated the effects of sip volume on sensory perception and drinking comfort during the consumption of Jiangxiangxing Baijiu (JB). Six sip volumes (6, 9, 12, 15, 18, and 20 mL) were tested with 30 participants (15 males and 15 females). Results revealed gender-specific preferences: females tended to prefer sip volumes of 9–12 mL, while males were more likely to favor 18 mL. Using Temporal Dominance of Sensation (TDS) and Check-All-That-Apply (CATA) methods, it was found that oral sensations of sweetness and sauce flavor, as well as post-pharyngeal sensations of “smoothness,” “mellowness,” and “lingering aftertaste,” enhanced drinking comfort. In contrast, oral sensations of spiciness and bitterness, along with post-pharyngeal sensations of “pungency,” “thinness,” “blandness,” and “momentary aftertaste,” impaired comfort. Notably, females may place greater emphasis on oral perception, whereas males could focus more on post-pharyngeal sensations. A novel flavor analysis identified 20 key compounds that influence JB perception. The insights from this research provide valuable contributions to improving the drinking experience of JB.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF CHEMICAL AND ENGINEERING DATA
·
2026
·
IF 2.4
Jingwen Wang,Fanjing Wei,Qingqing Zhang,Shaofu Li,Lijie Guan,Hao Qin,Zhiwen Qi
Deep eutectic solvents (DESs) have emerged as promising alternatives to conventional solvents due to their tunable properties and potential environmental benefits. While most studies focus on ionic DESs, nonionic DESs remain less explored. In this work, four nonionic deep eutectic solvents (DESs) are prepared using diethylene glycol dimethyl ether or isoquinoline as hydrogen-bond acceptors (HBA) and cyclohexanecarboxylic acid, nonanoic acid, or 1-naphthylamine as hydrogen-bond donors (HBD) at specific molar ratios. Their fundamental thermophysical properties, including density, viscosity, surface tension, electrical conductivity, and melting point, are systematically measured over the temperature range of 303.15–343.15 K. The temperature dependence of all measured properties is quantitatively analyzed using appropriate empirical or Arrhenius-type correlations. The results provide insights into the influence of molecular composition on nonionic DES behavior, expanding the experimental database and highlighting their potential as low-viscosity, tunable, and versatile solvents for chemical engineering applications.
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Mengdi Chen,Jianing Ye,Dong Wang,Buyu Liu,Mingqin Li,Ting Li,Xinxia Zhang,Li Wang
Flavor compounds with different structures showed distinct binding patterns. • Heat treatment enhanced flavor-protein interaction. • Binding was mainly driven by hydrogen bonding and hydrophobic forces. • Glutelin contributed 65.9% to overall flavor binding. • Docking energies showed protein-dependent correlations with binding behavior. Interactions between rice proteins and flavor compounds play a crucial role in flavor retention and release. This study examined binding mechanisms with five key flavor compounds and the influence of heat treatment. Rice proteins showed relatively strong binding to (E)-2-octenal (45.05%), 1-octen-3-one (22.07%), and 2-pentylfuran (46.63%), which increased after heating, while 1-octen-3-ol (13.03%) and nonanoic acid (19.95%) showed lower binding and were more easily released. Spectroscopic analyses indicated that protein–flavor interactions were mainly driven by static quenching and accompanied by structural changes in rice proteins. Molecular docking suggested hydrogen bonding and hydrophobic interactions as the major contributors, with residues ARG103, THR155, ARG52, and LYS143 in albumin, globulin, prolamin, and glutelin, respectively, contributing to binding specificity. Regression analysis quantified the contributions of storage proteins, highlighting glutelin as the dominant contributor (65.9%). Overall, this study clarifies protein–flavor interaction mechanisms and their heat-induced changes, offering insights for improving rice flavor quality. Download: Download high-res image (258KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Food Chemistry-X
·
2025
·
IF 8.2
Yuxin Wang,Jin Liu,Suzhen Li,Jizhen Fu,Xiaowen Wang,Li Li,Xu Jing
The widespread use of triazole fungicides has raised concerns over residual. This study presents an automated, environmentally friendly, simple, and efficient method for detecting triazole fungicides in food samples, utilizing high-throughput liquid processing, dispersive liquid-liquid microextraction, and ultra-high-performance liquid chromatography-tandem mass spectrometry. The automated liquid handling workstation was employed to automate the whole sample pre-treatment process. Fatty acid, bio-based solvent, and saturated sodium chloride solution were used as the extractant, dispersant, and demulsifier, respectively. The whole operation process obviated the use of toxic reagents and eliminated the need for time-consuming centrifugation. The linear ranged from 0.01 to 1 μg L −1 with limits of detection and quantification of 0.003 μg L −1 and 0.01 μg L −1 , respectively. Ten triazole fungicides were successfully detected in food samples with recoveries of 70.1 %–105.7 %. The automation of dispersive liquid-liquid microextraction demonstrates huge potential for broad applicability within the field of food safety testing.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ACS Sustainable Chemistry & Engineering
·
2025
·
IF 7.3
Na Wang,Yun Tian,Xu Wu,Huanyu Liu,Hongsheng Lu,Yuanqiang Zhu
Curcuminoids make up a class of valuable natural pigments, and their green and efficient extraction has always been a challenging task. This study synthesized hydrophobic deep eutectic solvents (HDESs) from natural anisyl alcohol and saturated fatty acids. With the assistance of pulsed ultrasound, these green HDESs efficiently extracted curcuminoids from the plant Curcuma longa L. The extraction parameters were optimized using single-factor experiments and response surface methodology (RSM). The optimal extraction conditions were obtained as follows: a molar ratio of anisyl alcohol to n-nonanoic acid of 1:2, a liquid–solid ratio of 21.58 mL·g–1, an extraction temperature of 25 °C, an ultrasonic time of 25 min, and an extraction time of 60 min. Under these conditions, the extracted curcuminoids amount reached 115.64 mg·g–1 in a single extraction process, outperforming the traditional solvent methanol. The sustainable extraction of curcuminoids by HDES was shown to be as high as 743 mg·g–1 through sequential extraction. Quantum chemical calculations and molecular dynamics simulations investigated the interactions between HDES and curcuminoids during extraction. This work presents a natural green HDES that can replace traditional organic solvents for the efficient extraction of curcuminoids, further promoting the application of green solvents in natural product extraction.
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2025
·
IF 4.6
Yawen Zhang,Hongli Zhang,Jiangong Ma,Jing Zhao,Huajuan Yin,Xu Jing,Xiaowen Wang
With the advent of new-generation green extraction solvents, deep eutectic solvents (DESs) present significant prospects for the extraction of bioactive substances. In this study, saponins were extracted from oats using an ultrasonic-assisted method with green DESs, replacing conventional toxic organic solvents. Adding sodium chloride markedly reduced solubility, resulting in the separation of two phases from the extract: DES and water. The saponins were separated into the water phase, while the DES was reused in subsequent extractions, supporting extractant recycling and promoting sustainable development. Adding salt offers a more gentle, convenient, and cost-effective alternative to current phase separation methods, such as pH adjustment, temperature variation, and carbon dioxide or nitrogen gas application. Optimizing the extraction and recovery parameters yielded the highest oat saponin extraction efficiency at 18.73 mg g –1 , and the recovery was 86.4 %. When compared with ethanol extracts, DES extracts exhibited superior antioxidant activity. Lastly, the greenness of this extraction method was confirmed through three greenness evaluation programs of greenness. The extraction method based on emerging responsive solvents can be extended to other hydrophilic bioactive substances.
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2026
·
IF 10.4
Tianyu Dong,Shuwei Wang,Panpan Wu,Jie Sun,Haitao Chen,Shuqi Wang
As a popular seasoning, fried pepper oil (FPO) conveniences the cooking of cuisine. However, it is susceptible to rancid off-flavors during storage. Therefore, the aim of this study was to explore the formation pathways of off-flavor compounds using molecular sensory science. 92 volatile compounds were identified under different storage conditions using headspace solidphase microextraction-gas chromatography–mass spectrometry (HS-SPME-GC–MS). The off-flavor of FPO mainly originated from aldehydes and acids. By orthogonal partial least squares-discriminant analysis (OPLS-DA), 24 compounds were determined as differential marker compounds for distinguishing FPOs for different storage conditions. Based on modeling experiment and isotopic tracing, limonene, linalool and linoleic acid were identified as the main producers of off-flavor compounds. Random forest was the optimal model for screening fresh and storage FPOs. 7 VOCs have been identified as key factors influencing the flavor quality of FPOs. The results provide a theoretical guidance for the regulation of off-flavor in FPO.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
CHROMATOGRAPHIA
·
2026
·
IF 1.6
Wang Meng,Zhang Renjun,Shang Lulu,Zhang Jingzhen,Wang Liwei,Zhang Mo
Comprehensive profiling of carboxyl metabolites (CMs) is critical for biomarker discovery in disease pathogenesis but remains challenging due to matrix interference and poor ionization in mass spectrometry (MS). To overcome these limitations, we developed APH (amino-terminated polyuria–magnetic hexamethylenediamine composite), an integrated chemoselective probe for superior separation and detection. APH combines a magnetic Fe₃O₄@SiO₂ core for rapid isolation, a functionalized polyurea shell with high-density binding sites, a chemoselective moiety for covalent CMs capture, and a cleavable linker incorporating an MS signal-enhancing tag. This design enables specific enrichment of CMs directly from complex biosamples and efficient matrix removal via magnetic separation and gentle analyte release. Applied to mouse cecum samples, APH demonstrated deep carboxyl sub-metabolome profiling capabilities. By effectively reducing matrix suppression and enhancing sensitivity, APH facilitates the annotation of low-abundance CM biomarkers previously obscured in conventional analyses. This platform advances separation science for targeted metabolomics in biomarker research.
✓ 已验证
产品关联
DOI
高影响因子
Foods
·
2026
·Vol. 15
·期 17
·3002
·
IF 6
Min Li,Yulin Wang,Huajuan Yin,Xu Jing,Yunlong Li
Triazole fungicides (TFs) are widely used in cereal production due to their potent fungicidal activity and broad-spectrum efficacy. Nonetheless, residues of TFs in food products may pose risks to food safety and human health. Therefore, the development of efficient and environmentally friendly sample preparation methods is paramount for the reliable determination of TFs. Herein, a novel green solvent-based dispersive liquid–liquid microextraction method coupled with high-performance liquid chromatography (DLLME-HPLC) was developed for the determination of TFs in cereal samples. The prepared magnetic deep eutectic solvents (MDESs), composed of nonanoic acid and ferric hydroxide, served as green, magnetically responsive extraction solvents, enabling rapid magnetic separation without centrifugation. Four bio-based solvents (BBSs) were investigated as green dispersive solvents to facilitate the dispersion of MDESs and replace conventional toxic organic dispersants, thereby further enhancing the environmental sustainability of the extraction procedure. Owing to the combined effects of hydrophobic interactions, hydrogen-bonding networks, and magnetic responsiveness, the proposed method achieved efficient extraction and rapid phase separation while minimizing solvent consumption and operational complexity. The greenness of the method was evaluated using multiple green analytical chemistry metrics, confirming its low environmental impact, reduced waste generation, and improved operational safety compared with conventional DLLME procedures. Under optimized conditions, the method was successfully applied to determine TFs in rice, wheat, corn, buckwheat, and oat samples, achieving recoveries ranging from 75.0% to 101.9% and relative standard deviations of 1.6–4.8%. The developed DLLME method provides a rapid, sensitive, and environmentally friendly strategy for cereal pesticide residue analysis and expands the application of MDESs and BBSs in green sample preparation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Kaige Zhang,Yanrong Chen,Jing Wang,Rong Guo,Guifen Zhu
A novel supramolecular deep eutectic solvent based ferrofluid for vortex-assisted liquid-liquid microextraction (SUPRADES-FF-VA-LLME) method was developed firstly for extraction of Alkylphenols (APs) from water and beverage samples. In this method, the SUPRADES composed of hydroxyethyl-β-cyclodextrin, thymol and caprylic acid was firstly designed, synthesized and then used as carrier liquid for ferrofluid. The influencing parameters were screened by a plackett-burman design and optimized by a central composite design. Under optimal conditions, the linear range of 4-heptylphenol, 4-octylphenol and 4-nonylphenol was 0.3–400, 0.2–400 and 5–400 μg L −1 , respectively, with R 2 ≥ 0.9990. And the limit of detection and the quantification of this method were 0.05–1.5 μg L −1 and 0.2–5 μg L −1 , respectively. Both intra-day and inter-day precision ( n = 5) were ≤2.1 %, and the enrichment factor were 22–24. After microextraction, phase separation was quickly completed with the help of an external magnet, without the need of centrifugation equipment, greatly simplifying the operation steps and shortening the extraction time (∼2 min). Additionally, due to the introduction of hydroxyethyl-β-cyclodextrin, the encapsulation effect between its hydrophobic cavity and APs significantly enhances its molecular recognition ability, the method modification resulting in 19–29 % increase in extraction efficiency. Extraction mechanism was also studied by density functional theory. Combined with high performance liquid chromatography-fluorescence, this method was used for determination of APs in environmental water and beverages with spiked recovery of 98.4–102.4 %. The SUPRADES-FF-VA-LLME provides a new technique for the selective separation of pollutants, which is expected to be widely used in the field of food analysis and environmental monitoring.
✓ 已验证
产品关联
DOI
高影响因子
Food Chemistry-X
·
2023
·
IF 6.1
Min Wang,Luyao Zhao,Yu Niu,Shu Qin,Lixin Zhang,Liyan Jia,Xu Jing
In this study, a magnetic deep eutectic solvent coupled with dispersive liquid–liquid microextraction using high-performance liquid chromatography (MDES-DLLME-HPLC) was developed to detect strobilurin fungicides. The green hydrophobic MDES synthesized by methyltrioctylammonium chloride, ferric chloride, and heptanoic acid was used as an extraction solvent, which was dispersed by vortex and separated by an external magnetic field. The use of toxic solvents was avoided, and the separation time was reduced. The best experimental results were obtained through single factor and response surface optimization. The method had a good linear relationship with R 2 > 0.996. The limit of detection (LOD) ranged from 0.001 to 0.002 mg L −1 . The extraction recoveries were 81.9–108.9%. The proposed method was rapid and green, and it has been successfully applied to detection of strobilurin fungicides in water, juice, and vinegar.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
ANALYTICA CHIMICA ACTA
·
2022
·
IF 6.911
Ang Li,Song Xue,Yu Xu,Sihui Ding,Di Wen,Qi Zhang
A critical challenge in using deep eutectic solvents (DESs) in capillary electrophoresis (CE) is to develop separation systems in which a DES can really work as a single entity. To achieve this, the authors recently demonstrated a novel strategy that takes advantage of the aqueous dispersibility of hydrophobic DESs (or more accurately hydrophobic eutectic solvents (HESs)). However, the previous work was limited only to the separation of achiral analytes, e.g., analogues, homologues, and isomers. The present study was designed as a follow-up study in order to explore the feasibility of employing HES-type pseudo-stationary phases (PSPs) in CE for chiral separations . By using carboxymethyl-β-cyclodextrin (CM-β-CD) as a model chiral selector, we provide the first evidence that there is a potential synergistic effect between HESs and traditional chiral selectors. Specifically, the combined use of HES (−)-menthol:octanoic acid and CM-β-CD allowed excellent enantioseparations of several basic drugs which were not able to be resolved in the single CM-β-CD system. The enantioresolutions were significantly improved while the migration times of the enantiomers were also shortened due to the hydrophobic mechanism of the HES-type PSP. Critical factors influencing the novel chiral CE system were systematically investigated. Since HESs are considered as “designer” solvents with highly tunable properties, this study demonstrates the potential of employing HESs (or HDES)-type PSPs in CE for chiral separations .
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）