Waste and Biomass Valorization
·
2024
·Vol. 15
·期 7
·4353-4372
·
IF 2.6
Shankaranarayana Sahana Hosanagara,Gajanana Vijayalaxmi Karki,Chavan Mohan,Chavannavar Suvarna V.,Doddanagappa Shobha
Purpose To analyse phytochemical composition, antioxidant potential, antimicrobial activity and α-amylase, α-glucosidase and xanthine oxidase inhibitory potential of corn silk extracts derived from the Syngenta 5414 corn variety. Methods Corn silk sample was lyophilized and extracted using 80% ethanol, methanol, water or acetone. Phytochemicals were qualitatively screened and bioactive compounds were identified through GCMS. Antimicrobial activities were evaluated using the agar well method for bacteria and fungal biomass method for fungi. The extracts were subjected to evaluation for their antidiabetic activity through α-amylase and α-glucosidase inhibitory assays, while their anti-gout potential was assessed through xanthine oxidase inhibitory assay, encompassing all four solvent extracts in the study. Results Phytochemical screening revealed the presence of phenols, flavonoids, tannins, alkaloids, sterols, protein xanthoproteic, and cardiac glycosides in the extracts. The Folin-Ciocalteu and AlCl 3 assays demonstrated higher yields of phenolics and flavonoids in 80% ethanolic extract. Furthermore, the extracts remarkably scavenged reactive oxygen species like DPPH, ABTS and elicited considerable ferric ion reducing antioxidant power. GC–MS analysis identified 21 compounds in the 80% ethanolic extract, with 1,2,3-Propanetriol-1-acetate, n-Hexadecanoic acid, and 4H-Pyran-4-one,2,3-dihydro-3,5-dihydroxy-6-methyl- as major components. Antimicrobial assays demonstrated the ethanolic (80%) and methanolic extract's remarkable ability to inhibit the growth of Gram-positive bacteria and exhibit anti-fungal properties. The ethanolic (80%) extract exhibited an IC 50 value of 0.70 ± 0.02 and 0.71 ± 0.01 mg against α-amylase and α-glucosidase, respectively, and 33.76 ± 0.43 mg against xanthine oxidase. Conclusion Corn silk exhibits potential as a valuable reservoir of natural bioactive compounds endowed with a wide array of health-promoting properties. Graphical
研究领域:
天然产物化学
·
药用植物学
·
生物化学
·
药物代谢
·
微生物学
·
内分泌药理学
·
代谢性疾病
✓ 已验证
DOI
高影响因子
Petroleum Science
·
2021
·Vol. 19
·期 2
·608-618
·
IF 4.09
Jin-Sheng Sun,Zong-Lun Wang,Jing-Ping Liu,Kai-He Lv,Fan Zhang,Zi-Hua Shao,Xiao-Dong Dong,Zhi-Wen Dai,Xian-Fa Zhang
The demand for non-toxic and biodegradable shale inhibitors is growing in the drilling industry. In this paper, the effect of notoginsenoside (NS) as a new, environmentally friendly inhibitor of shale hydration is systematically studied for the first time. The inhibition performance of NS was evaluated via inhibition evaluation tests, including mud ball immersion tests, linear expansion tests, shale rolling recovery tests, and compressive strength tests. The inhibition mechanism of NS was analyzed using Fourier transform infrared spectroscopy (FTIR), contact angle measurements, particle size distribution determination, thermogravimetric analysis (TGA), and scanning electron microscopy (SEM). The experimental results demonstrate that NS is able to adhere to the clay surface, forming a hydrophobic film that prevents the entry of water molecules and inhibiting the hydration dispersion of the clay. Because of this, NS can maintain the original state of bentonite pellets in water, which can effectively reduce the swelling rate of bentonite, increase the recovery rate of shale drill cuttings, maintain the strength of the shale, and therefore maintain the stability of the borehole wall during drilling. In addition, NS is non-toxic, degradable, and compatible with water-based drilling fluids. The above advantages make NS a promising candidate for use as an environmentally friendly shale inhibitor.
研究领域:
石油工程
·
钻井液化学
·
环境材料科学
·
胶体与界面化学
·
可持续能源技术
✓ 已验证
DOI
高影响因子
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
·
2019
·Vol. 103
·期 14
·5907-5916
·
IF 3.67
Qiu Yongting,Wang Zhihong,Liu Feng,Liu Junxia,Tan Kaiting,Ji Ruibo
Allelopathy by hydrophytes can be utilized to control algal blooms. This study was conducted to investigate the allelopathic effect (inhibition) of Scenedesmus quadricauda on Microcystis flos-aquae . When M. flos-aquae was co-cultured with S. quadricauda , the secretion of high-MW biopolymer by M. flos-aquae was inhibited by S. quadricauda . We further identified the allelochemicals and found that 4-tert-butylpyrocatechol (TBC) was the main active ingredient that could inhibit the growth of M. flos-aquae . When the dose of TBC was larger than 0.2 mg/L, almost all of the M. flos-aquae died. Additionally, TBC was found to suppress the growth of M. flos-aquae by disturbing the synthesis and secretion of proteins and polysaccharides and harming the chlorophyll to affect the light harvesting of algal cells. Therefore, TBC has the potential for use as a potential and promising algaecide to restrain the biomass of M. flos-aquae .
研究领域:
水生生物学
·
环境微生物学
·
化学生态学
·
藻类生理学
·
生物防治
✓ 已验证
DOI
高影响因子
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
·
2023
·Vol. 30
·期 58
·121908-121914
·
IF 5.8
Zhang Dong-Chi,Ullah Abid,Tian Peng,Yu Xiao-Zhang
Root architecture is the temporal and spatial configuration of root system in the heterogeneous matrix of soil that is prone to chemical stresses. Gallium (Ga) is among the emerging chemical pollutants that are mostly associated with high-tech industries, specifically associated with semiconductors. In view of its potential risk and increasing distribution in the environment, this study was designed to evaluate the inhibition rate, Ga distribution in different tissues, and root architecture of rice seedlings under different concentrations of Ga. We observed that 2.59, 46.7, and 168.2 mg Ga/L were minimum (EC 20 ), medium (EC 50 ), and maximum (EC 75 ) effective concentrations for rice plants that corresponded to the 20, 50, and 75% inhibition on the relative growth rate, respectively. Distribution of Ga in rice tissues showed that accumulation of Ga was much higher in roots than shoots of rice seedlings, and it increased with an increase in Ga doses. Evan blue staining technique reveals that the number of damaged/dead cell was dose-dependent on Ga. Moreover, several traits associated with root system architecture demonstrating that rice root system architecture altered in response to Ga stress. Collectively, the results reveal that Ga exposure inhibited the growth and development of rice plants. This study will enhance our understanding that how different concentrations of Ga in the environment can affect plants; however, more comprehensive studies are essential to further determine plant response against Ga stress.
研究领域:
植物生理学
·
环境毒理学
·
土壤生物学
·
重金属污染
·
作物科学
✓ 已验证
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2018
·
IF 5.667
Xiaoyun Lin,Zhenmao Zhu,Chengfei Zhao,Shaoguang Li,Qicai Liu,Ailin Liu,Liqing Lin,Xinhua Lin
In this study, we developed a simple, sensitive and label-free colorimetric sensor for trypsin and its inhibitor using oxidase mimicking activity of protamine-stabilized platinum nanoparticles units (Pro-PtNPs units). Protamine is designed to stabilize PtNPs and served as the substrate of trypsin hydrolysis. The results show that protamine combines several PtNPs together to form active units, which have stronger oxidase mimicking activity than other PtNPs. In addition, the Michaelis constant of the Pro-PtNPs units is smaller than negatively charged citrate capped PtNPs, suggesting that the positively charged Pro-PtNPs units have better affinity with 3,3′,5,5′-tetramethylbenzidine (TMB), which is inconsistent with previous reports. The protamine stabilizer could be hydrolyzed in the presence of trypsin, and the Pro-PtNPs units would be decomposed and aggregated, resulting in a decrease of catalytic activity of Pro-PtNPs units. The color of the solution would be reduced according to the decrease of catalytic activity, so the catalytic activity is linearly related to UV absorbance. The linear range of trypsin detected by this new method is 0.06 μg/mL˜0.6 μg/mL, and the detection limit down to 0.03 μg/mL. Pro-PtNPs units have been successfully applied to the determination of serum trypsin and screening of inhibitors.
研究领域:
生物化学
·
纳米医学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Energy Chemistry
·
2022
·
IF 13.599
Xi Wang,Yong Wang,Yiyu Wu,Yunmiao Fan,Yang Tian
Li 6.4 La 3 Zr 1.4 Ta 0.6 O 12 (LLZTO) solid garnet-type electrolyte has been widely reported due to its outstanding safety and electrochemical stability. However, the inherent rigidity and brittleness of LLZTO lead to poor contact with anode/cathode and the operation failure of full cells. Herein, the dual-interlayers are constructed as the fast interfacial ion-migration channel by using Ti 3 C 2 T x (MXene, T x is –O, –OH, –F) with trace ionic liquid (IL), which promote the intimate contact between LLZTO and anode/cathode and suppress Li-dendrites growth. Notably, IL can wet the cathode to promote intimate interface contact and be decomposed into some inorganic compounds (such as Li 3 N, LiF, and Li 2 S x ), resulting in reduced interfacial resistance and fast Li-ion transportation. Consequently, in the prepared Li-symmetric cell, the interfacial resistance on the anode side plunges to 33.1 Ω cm −2 , and stably maintains over 1000 h without short circuit at 0.05 mA cm −2 . The full cell of Li|LiFePO 4 delivers a high initial capacity of 158.52 mA h g −1 and outstanding retention of 90.18% after 100 cycles at 60 °C and 0.2 C. Our work provides an efficient strategy to design dual-interlayers between LLZTO and anode/cathode for the interfacial modification to enhance the performance of solid garnet batteries.
研究领域:
材料科学
·
电化学
·
固态电池
·
界面工程
·
能源材料
✓ 已验证
DOI
高影响因子
Biomed Research International
·
2020
·Vol. 2020
·期 1
·5084057
·
IF 2.276
Li Yang,Yiwei Fang,Ronghua Liu,Junwei He
Dendropanax dentiger root is a traditional medicinal plant in China and used to treat inflammatory diseases for centuries, but its phytochemical profiling and biological functions are still unknown. Thus, a rapid, efficient, and precise method based on ultra high-performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UHPLC-Q-TOF-MS/MS) was applied to rapidly analyse the phytochemical profiling of D. dentiger with anti-inflammatory and antioxidant activities in vitro . As a result, a total of 78 chemical compositions, including 15 phenylpropanoids, 15 alkaloids, 14 flavonoids, 14 fatty acids, 7 phenols, 4 steroids, 4 cyclic peptides, 3 terpenoids, and 2 others, were identified or tentatively characterized in the roots of D . dentiger . Moreover, alkaloid and cyclic peptide were reported from D . dentiger for the first time. In addition, the ethanol crude extract of D. dentiger roots exhibited remarkable anti-inflammatory activity against cyclooxygenase- (COX-) 2 inhibitory and antioxidant activities in vitro . This study is the first to explore the phytochemical analysis and COX-2 inhibitory activity of D. dentiger . This study can provide important phytochemical profiles and biological functions for the application of D. dentiger roots as a new source of natural COX-2 inhibitors and antioxidants in pharmaceutical industry.
研究领域:
天然药物化学
·
药用植物学
·
炎症生物学
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自由基生物学
·
药物代谢
✓ 已验证
DOI
高影响因子
Biomed Research International
·
2018
·Vol. 2018
·期 1
·5314320
·
IF 2.583
Hong-Xin Cui,Fang-Fang Duan,Shan-Shan Jia,Fang-Rong Cheng,Ke Yuan
Torreya grandis Fort. ex Lindl. is a plant belonging to the Taxaceae family and Torreya grandis cv. Merrillii is the only grafted and thoroughbred species belonging to this species. In this study, we extracted five different seed oils, including T. grandis seed oil (TGSO), T. grandis “Xiangyafei” seed oil (XYSO), T. grandis “Zhimafei” seed oil (ZMSO), T. grandis “Majus”seed oil (TGMSO), and T. grandis “cunguangfei” seed oil (CGSO) using physical pressure. The resulting extracts were analyzed to determine their fatty acid composition, antioxidant activity, and inhibitory activity towards tyrosinase. The results of the antioxidant activity assays revealed that XYSO and ZMSO exhibited much greater DPPH radical scavenging activity and ferric reducing power than TGSO. Notably, all five of the seed oils showed dose-dependent inhibitory activity towards tyrosinase. XYSO and TGSO gave the highest activities of all of the seed oils tested in the current study against monophenolase and diphenolase, with IC 50 values of 227.0 and 817.5 μ g/mL, respectively. The results of this study show that wild TGSOs exhibit strong antioxidant and tyrosinase inhibition activities. These results therefore suggest that wild TGSOs could be used as a potential source of natural antioxidant agents and tyrosinase inhibitors.
研究领域:
植物化学
·
食品科学
·
药用植物学
·
生物活性成分
·
天然产物化学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2015
·Vol. 5
·期 100
·82153-82158
·
IF 3.84
Wei-ping Hu,Guo-dong Cao,Jin-hua Zhu,Jia-zhong Li,Xiu-hua Liu
Batatasins are endogenous plant hormones found in yams and other related plant species. These plants are widely consumed as botanical dietary supplements in many parts of the world. This study investigated the inhibitory effects and mechanisms of Batatasin I, III, IV, V against α-glucosidase regarding their antidiabetic activities. The results revealed that Batatasin I, III, IV inhibited α-glucosidase in a reversible and noncompetitive manner, with IC50 values of 2.55, 1.89 and 2.52 mM respectively, while Batatasin V completely abolished its inhibitory activity even at the highest concentrations tested. Furthermore, a class of Batatasin-derived compounds with different substitution patterns was synthesized and subjected to the assay to clarify the structure–activity relationships, which suggested that the hydroxyl at the C-2′ position may play a significant role in improving the inhibitory activities. Their probable binding modes and the specificity of the binding sites were studied using molecule docking simulation. It was concluded that Batatasins, especially Batatasin III and IV, are promising α-glucosidase inhibitors, which therefore could be used as functional food to alleviate postprandial hyperglycemia and as potential candidates for the development of antidiabetic agents.
研究领域:
天然产物化学
·
药理学
·
分子生物学
·
药物代谢
·
功能食品
✓ 已验证
DOI
高影响因子
JOURNAL OF POWER SOURCES
·
2019
·
IF 7.467
Liming Jin,Jie Ni,Chao Shen,Fenglai Peng,Qiang Wu,Donghao Ye,Junsheng Zheng,Gaoran Li,Cunman Zhang,Zhoupeng Li,Jim P. Zheng
A metallically conductive TiB 2 is developed to construct multifunctional separator toward improved lithium-sulfur (Li–S) battery performance. Coupled with two-dimensional graphene, the obtained TiB 2 @G separator fulfills a synergistic combination of strong physical and chemical sulfur immobilization as well as a high-efficiency sulfur reutilization, thus establishing a robust barrier against the polysulfide shuttling and enabling a fast and durable sulfur electrochemistry . As a result, cells based on TiB 2 @G separator exhibit a high sulfur utilization with 1350 mA h g −1 capacity at 0.05C, superb rate capability up to 5.0C, and excellent cyclability with a high capacity retention over 85% after 300 cycles at 0.5C. Moreover, significantly mitigated self-discharge and considerably high areal capacity of 5.8 mA h cm −2 can be also achieved, indicating the great promise of this separator design for the development of high-performance Li–S batteries.
研究领域:
电化学
·
能源材料
·
纳米材料科学
·
储能技术
·
电池化学
✓ 已验证
DOI
高影响因子
BIOSENSORS & BIOELECTRONICS
·
2014
·
IF 6.451
Qin Xu,Lijuan Cai,Huijie Zhao,Jiaqian Tang,Yuanyuan Shen,Xiaoya Hu,Haibo Zeng
An enzymatic procedure based on a catalase biosensor for the detection of forchlorfenuron (CPPU) has been reported in this work. Catalase was immobilized on boron nitride (BN) sheets dispersed in chitosan by adsorption. The immobilized catalase exhibited direct electron transfer character and excellent electrocatalytic activity towards H 2 O 2 reduction. After introducing CPPU into the H 2 O 2 containing phosphate buffer solution , the catalase-catalyzed H 2 O 2 reduction current decreased. By measuring the current decrease, CPPU can be determined in the range of 0.5–10.0 µM with the detection limit of 0.07 μM. The non-competitive inhibition behavior of CPPU towards catalase was verified by the Lineweaver–Burk plots. Long stability character has been ascribed to this biosensor. Possible use of this biosensor in flow systems is illustrated. The proposed biosensor has been successfully applied to CPPU determination in fruits samples with satisfactory results.
研究领域:
分析化学
·
生物传感
·
食品安全
·
酶学
·
纳米材料
·
电化学
·
药物残留检测
✓ 已验证
DOI
高影响因子
Surfaces and Interfaces
·
2024
·
IF 5.7
Peilin Cao,Cong Wang,Linpeng Liu,Kaiwen Ding,Jiahua He,Dejin Yan,Nai Lin,Ji'an Duan
The reliability of Cu bonding technology in three-dimensional integration packaging is limited by high sintering temperatures and the growth of oxide at the joining interface. Hence, we propose a bionic adhesion interface of creeper sucker on the Cu substrate and covered with monolayer graphene, which increases the shear strength by 3 times compared to the conventional flat Cu substrate. The covered graphene layer effectively inhibits the generation of oxide at the joint interface and maintains a high shear strength after aging at 300 °C for 48 h Nanoscale Cu particles could reduce the chemical potential energy of the substrate surface , and stable bonding was achieved at 200 °C under a pressure of 2 MPa. Molecular dynamics simulation models reveal crystal structure evolution and residual stresses during the sintering process . This work demonstrates that bionic microstructures applied to copper bonding play an important role in interface enhancement, resulting in reliable bonding of Cu substrate at low temperatures. The method proposed here can provide insight into diversified applications including high-power light-emitting diodes soldering, SiC electronic devices, and flexible electrode interconnects.
研究领域:
材料科学
·
微电子封装
·
纳米技术
·
表面工程
·
固态物理
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）