JOURNAL OF MEMBRANE SCIENCE
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2026
·
IF 8.8
Zhang-Fu Shi,Peng Cheng,Yi-Fan Li,Jie Yang,Yan Chen,Xiao-Jing Guo,Xi Yan,Wan-Zhong Lang
Polyethylene glycol (PEG), a versatile non-ionic surfactant with excellent biocompatibility and robust chemical stability, offers significant potential for the precise regulation of interfacial polymerization (IP). In this study, PEG was introduced into the aqueous phase as an additive to modulate the interfacial diffusion behavior of piperazine (PIP). By systematically optimizing its molecular weight, concentration, and terminal group parameters, a polyamide (PA) active layer with a smaller and more uniformly distributed pore structure was successfully constructed. This optimized architecture effectively strengthened both the size exclusion and charge repulsion mechanisms of the nanofiltration (NF) membrane. Consequently, the optimal MP 1000 -10 membrane exhibited highly competitive NF performance, achieving an impressive Na 2 SO 4 rejection of 98.0% and a high water permeance of 11.5 L m −2 h −1 bar −1 . More importantly, tailoring the PEG terminal groups facilitated targeted control over the pore size and surface charge properties, significantly enhancing the removal of structurally and physicochemically diverse emerging organic contaminants (EOCs). Across a broad set of experimental parameters, PEG modification consistently delivers improved separation performance for membranes. With excellent stability, high efficiency and economic feasibility, this strategy provides solid technical and theoretical support for developing advanced separation membranes targeting high-efficiency EOCs removal.
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Foods
·
2026
·Vol. 15
·期 15
·2649
·
IF 6
Wei Dai,Min Quan,Guangli Yu,Qingsen Shang
Background/Objectives: Raffinose is a prebiotic trisaccharide fermented by human gut microbiota, yet the strain-level determinants of its degradation and associated metabolic outputs remain poorly characterized.Methods: In the present study, anaerobic fermentation, 16S rRNA gene amplicon high-throughput sequencing, culturomics, and metabolomics were conducted to address this question.Results: In vitro fermentation of raffinose was performed using fecal samples from 16 healthy donors, and substantial interindividual variation was observed in substrate consumption, microbiota composition, and short-chain fatty acid production. Through culturomics, 204 bacterial strains spanning 18 species were isolated, among whichLimosilactobacillus reuterisubsp.reuteriexhibited the highest raffinose-degrading efficiency. Untargeted metabolomics comparingL. reuterisubsp.reutericultured on raffinose versus glucose revealed a distinct metabolic shift, with 290 metabolites significantly upregulated, including the putatively identified fructooligosaccharide 1-kestose—a compound with documented prebiotic and anti-inflammatory properties. KEGG enrichment further highlighted coordinated remodeling of nucleotide and amino acid metabolism.Conclusions: Collectively, this study provides a strain-level framework for understanding how raffinose shapes the gut microbiota and identifiesL. reuterisubsp.reuterias a key metabolic hub linking prebiotic consumption to the production of bioactive metabolites.
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JOURNAL OF MEMBRANE SCIENCE
·
2026
·
IF 8.8
Cheng Yi,Qian Liu,Tengfei He,Yue Yao,Lijia Liu,Chunhong Zhang,Chao Wang
Membranes with excellent chlorine resistance are required for stable operation and long service life. Traditional polyamide (PA) nanofiltration (NF) membranes typically suffer from inadequate chlorine resistance. To overcome this critical challenge and the long-standing problem of insufficient permeability, a novel polyesteramide (PEA) NF membrane was fabricated. Specifically, naringin (NG), a naturally occurring polyphenol rich in hydroxyl groups, was introduced as a co-monomer with piperazine (PIP) in the aqueous phase for interfacial polymerization with trimesoyl chloride (TMC) in the organic phase. The chlorine-susceptible amide groups were partially substituted by intrinsically chlorine-resistant ester groups in the fabricated PEA membrane. As a result, the chlorine resistance of the PEA membrane was greatly enhanced, with Na 2 SO 4 rejection remaining above 93 % after exposure to 20,000 ppm h of free chlorine. The resulting PEA membrane exhibited reduced surface roughness and selective-layer thickness, coupled with a slight increase in pore size and free volume fraction, which was attributed to intermolecular interactions between NG and PIP in the aqueous phase. Consequently, the PEA membrane demonstrated a water flux approximately twice that of the PA membrane, while maintaining a high Na 2 SO 4 rejection rate of 99 % and rejecting more than 98 % of various antibiotics (e.g., cephalosporins and tetracyclines). Furthermore, the PEA membrane exhibited favorable antifouling performance, satisfactory anti-swelling property, and filtration stability under various conditions.
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JOURNAL OF MEMBRANE SCIENCE
·
2026
·
IF 8.8
Cunxian Lai,Wentian Zhang,Fangang Meng,Shanshan Zhao
Precise ion sieving by polyamide (PA) nanofiltration (NF) membranes relies on narrowly distributed subnanometer pores and tailored surface chemistry, yet simultaneously controlling both within a single interfacial polymerization (IP) process remains challenging. Here, we developed a density contrast-assisted sequential immersion strategy by preloading a porous substrate with a polyethyleneimine (PEI)/sucrose phase before piperazine (PIP) immersion. The preloaded phase regulated PIP storage and interfacial supply, enabling rapid PIP-dominated film formation and diffusion-limited growth, while limited PEI near the initial interface may participate in reaction before interfacial sealing. This reaction-diffusion process produced a thinner selective layer with an MWCO of approximately 190 Da, a narrowed pore-size distribution, and modified chemical and electrostatic characteristics. The resulting sequential immersion membrane (SIM-PA) achieved a Li + /Mg 2+ selectivity of 28.7 at a Mg 2+ /Li + mass ratio of 100:1 and maintained stable separation under moderately elevated salinity. Transport analysis suggested that the enhanced Mg 2+ /Li + discrimination mainly originated from strengthened steric and dielectric exclusion during ion partitioning and diffusion. Integrated with multistage NF and evaporation-precipitation, SIM-PA enabled lithium recovery from both simulated salt-lake brine and spent lithium-ion battery discharge wastewater. This work establishes density contrast-assisted sequential monomer loading as a practical route to NF membranes with narrow pore-size distributions for lithium recovery from complex saline streams.
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FOOD CHEMISTRY
·
2026
·
IF 10.4
Ru Jia,Sha Yan,Xuezhe Huang,Zongyan Cui,Xiaofeng Xue
Honey is primarily composed of sugars, with their profiles governing its quality. Twelve types of sugars in 784 honey samples, including 20 types of Chinese monofloral honeys, were accurately quantified by ultra-high performance liquid chromatography coupled with evaporative light scattering detection. Turanose (1.48 ± 0.63 g/100 g) was the most abundant oligosaccharide, followed by maltose (1.33 ± 0.43 g/100 g), and erlose (0.96 ± 0.80 g/100 g) was the predominant trisaccharide. Using unsupervised clustering, these honey samples were segmented into three clusters: high-oligosaccharide (e.g., jujube and fennel honey), high-glucose and low-oligosaccharide (e.g., rape, lychee and rubber honeys) and moderate-oligosaccharide clusters. The correlation analysis revealed strong correlations among turanose, maltulose, kojibiose and isomaltose, suggesting co-transformation among these sugars during honey ripening process and guiding future research directions. This study elucidated the sugar profile characteristics of Chinese honey, laying the foundation for enhancing its quality.
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ACS Applied Materials & Interfaces
·
2026
·
IF 8.2
Wan-Ting Lin,Chang Liu,Xiao-Wei Luo,Wan-Long Li,Zi-Lu Zhang,Si-Yuan Zhang,Zhi-Kang Xu,Ling-Shu Wan
Separation under high temperature is a crucial challenge for polymer nanofiltration (NF) membranes. Polyamide NF membranes with favorable compactness and pore size distribution are promising for boosting their thermal stability and high-temperature separation performance. Despite recent strategies to improve thermal stability, the effect of polyamide membrane compactness on structural changes and separation performance at high temperatures remains insufficiently explored. Herein, we propose a straightforward and effective concentration regulation strategy to address this challenge in the classic piperazine-trimesoyl chloride (PIP-TMC) interfacial polymerization system, focusing on the precise tuning of the polyamide network structure and the high-temperature NF performance through the controlled adjustment of monomer concentration and the relative ratios. Polyamide layer fabricated with a PIP/TMC ratio of 30:1.5 exhibits higher cross-linking degree than that with a PIP/TMC ratio of 2:1.5, and the NF membrane exhibits exceptional thermal stability, with MgSO4 rejection remaining >98.5% at 85 °C. Molecular dynamics simulations reveal that denser polyamide network possesses significantly weaker segmental motion, along with smaller changes in pore size distribution and fractional free volume at elevated temperatures. This concentration regulation strategy effectively enhances the intrinsic thermal stability without complex modifications and provides critical insights into polyamide segment evolution at high temperature.
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JOURNAL OF MEMBRANE SCIENCE
·
2026
·
IF 8.8
Zhongbiao Wang,Qiuyan Bi,Xin Shi,Zizhen Peng,Zhicheng Wang,Wenzhong Ma,Yakai Lin,Shiai Xu
In this work, we proposed a staged interfacial reaction strategy to regulate the formation of the polyamide selective layer by separating nascent-layer formation from subsequent densification, thereby addressing the mismatch between monomer diffusion and reaction kinetics in conventional interfacial polymerization (IP) and enabling high permeability and selectivity in nanofiltration (NF) membranes for Mg 2+ /Li + separation. The optimized membrane (SIP) was fabricated using 0.2 wt% BAPP and 0.1 wt% TMC for 120 s in Stage-I, followed by 0.5 wt% BAPP for 120 s in Stage-II. Compared with membranes prepared by conventional one-step IP, the SIP membrane exhibited a thinner selective layer (14.89 ± 1.16 nm), a higher amide-related O C–N content (50.96 at%), a more favorable hydration state, and a lower molecular weight cut-off (330 Da), indicating the formation of a thinner yet more compact and uniform polyamide network. Benefiting from these tailored structural and physicochemical features, the SIP membrane exhibited robust Mg 2+ /Li + separation over a broad range of feed Mg 2+ /Li + mass ratios, with high Mg 2+ rejection, low Li + rejection, and stable water flux. During long-term filtration tests, the Mg 2+ /Li + mass ratio in the permeate remained below 0.68, while the Mg 2+ rejection and separation factor were maintained at 95.57%–97.79% and 25.50–35.34, respectively. These results demonstrate that the staged interfacial reaction strategy is an effective platform for regulating polyamide selective layer formation and offers a promising route for lithium extraction from brines with high Mg 2+ /Li + mass ratios.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2026
·
IF 9.1
Shiwei Guo,Liang Gou,Yuhan Wang,Haoran Xiong,Xiaoying Ma,Ming Li,Chungang Yuan
The permeability–selectivity trade-off and the permanent hydraulic resistance introduced by conventional interlayers remain critical challenges for thin-film composite polyamide nanofiltration (NF) membranes. In this paper, we present a low-cost, transient polyester interlayer strategy that utilizes pyrogallol (PG) and trimesoyl chloride (TMC) to regulate interfacial polymerization (IP). A transient polyester interlayer strategy is presented, in which the PG-TMC layer serves as a temporary regulatory scaffold: it suppresses piperazine diffusion during interfacial polymerization and subsequently undergoes partial structural disintegration in aqueous environments, leaving behind a residual porous sublayer with tunable content, thereby avoiding the formation of dense, permanent mass-transfer barriers. This process of kinetic suppression resulted in the compression of the IP reaction zone, thereby yielding a significantly thinner (∼60 nm), smoother (Rq = 25.6 nm), and more uniformly porous polyamide selective layer in comparison to the pristine membrane (83 nm, Rq = 33.3 nm). Consequently, the optimized membrane achieved a ∼ 64% increase in pure water permeability (from 11.4 to 18.7 L m −2 h −1 bar −1 ) while maintaining high Na₂SO₄ rejection (95.0%). It is noteworthy that pharmaceutical rejection was significantly enhanced owing to the narrowed pore size distribution and reduced defect density, with cefalexin rejection rising from 82.6% to 95.0%. In the context of cyclic cross-flow fouling conditions, the modified membrane exhibited enhanced flux and favorable flux recovery, thereby substantiating that the observed permeability enhancement was not attained at the expense of antifouling efficacy. The stability of the separation selectivity was verified over a period of 32 h by conducting long-term cross-flow tests. In contrast to conventional permanent interlayers, the PG-TMC layer functions as a transient regulatory layer and undergoes partial structural disintegration in aqueous environments. This prevents the formation of dense permanent mass-transfer barriers. Utilizing commercially available reagents and a simple dip-coating process that is fully compatible with existing manufacturing lines, this strategy offers a scalable route toward high-performance NF membranes.
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ACS Applied Materials & Interfaces
·
2026
·Vol. 18
·期 30
·41834-41843
·
IF 7.8
Lin Wan-Ting,Chen Xiaohong,Luo Xiao-Wei,Li Wan-Long,Zhang Si-Yuan,Zhang Zi-Lu,Zhang Zi-Jun,Xu Zhi-Kang,Wan Ling-Shu
Separating monovalent ions from divalent ions remains a central challenge in resource recovery. While the classic poly(piperazine-amide) nanofiltration membrane exhibits superior rejection of divalent anion, the application in cation separation is constrained by the strongly negatively charged surface and limited size-sieving precision. To address this limitation, we propose a solvent treatment-induced optimization strategy for surfactant-tailored polyamide networks. The surfactant-assisted interfacial polymerization yields a dense and uniform nascent polyamide network that can withstand solvent treatment while preserving its cross-linked structure. Subsequent solvent treatment selectively removes oligomers trapped within the network, thereby refining the polyamide network architecture. This strategy facilitates the formation of a thinner polyamide selective layer that exhibits an attenuated negative surface charge and a more uniform pore size distribution. The optimized membrane achieves a dual enhancement in performance, exhibiting high mono-/divalent ion selectivity (Li + /Mg 2+ selectivity of 96.1 and Cl – /SO 4 2– selectivity of 1351) coupled with a high water permeance of 14.9 L m –2 h –1 bar –1 . This work provides a straightforward and effective method to refine surface properties and internal architecture of polyamide networks for efficient mono-/divalent ion separation.
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CARBOHYDRATE POLYMERS
·
2025
·
IF 12.5
Liping Xu,Dandan Sha,Rongfan Ren,Hongli Li,David Da Yong Chen
Oligosaccharides are carbohydrate polymers with prebiotic, immunomodulatory, and antimicrobial activities. However, their structural complexity makes it challenging for characterization. In this work, we demonstrated a powerful instant in situ methylation approach to derivatize oligosaccharides with tetramethylammonium hydroxide (TMAH) in an ambient ion source known as direct analysis in real time (DART). The reaction occurs instantaneously when the sample and TMAH mixture is bombarded by excited-state helium from the DART source, and the methylated species are simultaneously charged through the Penning process. Mass spectrometry (MS) showed the formation of partial, full, and per-methylation products, along with methylated saccharide fragments. Unique fragmentation patterns can be generated because of the enhancement on the structural differences of isomers when fully or partially methylated. By using accurate mass and tandem MS (MS/MS), we demonstrated that trisaccharide and pentasaccharide isomers with subtle structural variations produced distinctively characteristic fragment ions. Isomeric saccharides in mixtures were qualitatively identified, and trisaccharide isomers in real samples were quantified. Varying degrees of polymerization of oligosaccharides, and their stereochemical and other isomeric differences were directly characterized. This method is significantly simpler compared to currently used workflow, and the time-consuming chromatographic separation step was eliminated.
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SEPARATION AND PURIFICATION TECHNOLOGY
·
2025
·
IF 9
Chao Wang,Peijuan Chu,Tengfei He,Cheng Yi,Yue Yao,Lijia Liu,Chunhong Zhang
The application of membrane separation technology in wastewater treatment and pharmaceutical purification has attracted considerable attention. The development of a membrane with effective separation performance and antibacterial properties is of considerable interest for the separation and purification of antibiotics. Here, a thin-film composite (TFC) polyester membrane with effective antibiotic removal and antibacterial properties was fabricated via a facile one-step interfacial polymerization (IP) strategy. Naringenin (Nar), a natural product of flavonoid material derived from the pericarp, was utilized as the aqueous monomer. The suitable reactivity of Nar afforded the resulting membrane with a highly negative charged surface. The rejection performances for the antibiotics cephalothin, cefuroxime sodium, ceftriaxone sodium, and cefoperazone sodium were 96.3 %, 97.7 %, 99.2 %, and 99.8 %, respectively. The pure water permeance was 7.5 L m −2 h −1 bar −1 at a transmembrane pressure of 5 bar. The antibacterial efficacy was greater than 99.0 % against Escherichia coli and Staphylococcus aureus , attributable to the flavonoid structure of Nar. The present work proposed a feasible strategy to prepare TFC membranes with high nanofiltration performance and intrinsic antibacterial efficacy.
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Insects
·
2026
·Vol. 17
·期 2
·
IF 3
Yulong Guo,Haoyuan Zhang,Wenzheng Zhao,Yakai Tian,Dan Yue,Xueyang Gong,Kun Dong
Honeybees are vital pollinators that contribute substantially to global ecosystem stability and agricultural productivity.Camellia reticulata, a cross-pollinated crop species, depends on honeybees for successful reproduction.Apis ceranashows reluctance to pollinateC. reticulata, yet the molecular mechanisms underlying this phenomenon remain unexplored. In this study, we performed controlled feeding experiments in which adult workerA. ceranawere supplied with stachyose, raffinose, and their combination. We assessed physiological traits including survival rate, sucrose solution consumption, and body weight gain, alongside histological changes in intestinal cell structures. We conducted RNA-seq of gut tissues as well as 16S rRNA sequencing and metabolomic profiling. Our findings revealed that the mixed oligosaccharide treatment significantly reduced the survival rate of workers, and three oligosaccharide treatments significantly reduced sucrose consumption inA. cerana. Both mixed and single-oligosaccharide treatments caused pronounced intestinal cell damage and disrupted the gut microbial community structure. Among the gut microbes,Gilliamellaexhibited the most substantial decline in the stachyose group. Metabolomic analysis further demonstrated that oligosaccharide feeding significantly altered amino acid and galactose metabolism pathways, which may play critical roles in oligosaccharide utilization and directly influence honeybee survival. In summary, this study provides new insights into the molecular mechanisms underlyingA. ceranamortality associated withC. reticulatapollination. These findings not only enhance our understanding of host-diet-microbiota interactions in honey bees but also offer a theoretical basis for the integrated management ofA. ceranaforC. reticulatapollination and the development of oligosaccharide-adapted bee diets.
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