JOURNAL OF MEMBRANE SCIENCE
·
2026
·
IF 8.8
Xiaozhen Lu,Lin Wang,Bin Liu,Hong Peng,Xuewu Zhu
Nanofiltration (NF) for advanced drinking-water treatment has long been constrained by the need to remove contaminants while preserving beneficial mineral ions in health-oriented drinking water. Herein, an ethylene-glycol (EG)-regulated aqueous microenvironment was introduced to tailor the interfacial polymerization process. EG-mediated hydrogen bonding and modified interfacial thermodynamics jointly regulated piperazine diffusion, interfacial transport, and polymerization kinetics, producing polyamide NF membranes with enhanced negative charge surface density and a more uniform effective pore structure. Compared with the pristine membrane, the EG-20 membrane exhibited a thinner, more hydrophilic, and more negatively charged selective layer, together with a narrower pore-size distribution. The optimized EG-20 membrane achieved a permeance of 23.6 L m −2 h −1 bar −1 while maintaining Na 2 SO 4 rejection above 95.5%. In the treatment of natural surface water, dissolved organic matter removal reached approximately 92.1%, while partial passage of beneficial mineral ions was maintained, enabling effective organic contaminant removal with mineral preservation for health-oriented drinking water treatment. Moreover, high rejection of PFAS and antibiotics was maintained, mainly because steric exclusion and enhanced electrostatic repulsion compensated for the moderately enlarged effective pores. In addition, the membrane showed improved antifouling performance, as enhanced surface hydration and electrostatic repulsion reduced foulant adhesion and suppressed irreversible fouling. Overall, this microenvironment-regulation strategy provides a feasible route for developing NF membranes that integrate effective contaminant control, mineral preservation, and stable operation.
✓ 已验证
产品关联
DOI
高影响因子
DESALINATION
·
2026
·
IF 9.9
Yuwen Yang,Zhi Wu,Kelang Wang,Jingyi Wang,Yunrong Liao,Zhiming Zhang,Renjie Chen,Fei Pan,Wenjun Meng
High-value utilization of agricultural waste • Green and low-cost fabrication • Synergistic double-layer design • Efficient solar desalination performance • Practical applicability Sorghum distillers' grains (SDG) are abundant by-product of sorghum liquor production but are often underutilized. In this study, we report a form-stable, carbohydrate-based double-layer aerogel (DLA) fabricated via directional freezing followed by ambient-pressure drying, which avoids energy-intensive supercritical freeze-drying routes. Cellulose nanofibers (CNF) extracted from SDG via TEMPO-mediated oxidation were combined with sodium alginate to form a Ca 2+ -crosslinked skeleton, and an rGO/g-C 3 N 4 photothermal layer was integrated on top to construct the DLA evaporator. By tuning the rGO/g-C 3 N 4 ratio, A 3 (0.6/0.4, w /w) exhibited markedly enhanced dimensional stability during cycling, showing only 3.2% projected-area shrinkage after 10 days, compared with severe shrinkage in the control samples. Meanwhile, A 3 maintained efficient solar evaporation with an evaporation rate of 1.43 kg·m −2 ·h −1 and a photothermal conversion efficiency of 93.14% under simulated irradiation. Outdoor tests further confirmed robust freshwater production across seasons (maximum 2.74 kg·m −2 ·h −1 ), and the collected condensate satisfied WHO ion-concentration guidelines. This work demonstrates an ambient-pressure-drying-enabled, form-stable CNF aerogel platform for scalable solar desalination and SDG valorization.
✓ 已验证
产品关联
DOI
高影响因子
ANALYTICAL CHEMISTRY
·
2026
·Vol. 98
·期 30
·22484-22494
·
IF 7.3
Rao Yanhua,Yang Zhongyu,Long Yongteng,Yang Jiabao,Liu Nannan
Scandium (Sc), as a critical rare earth element (REE),
holds significant
application value in advanced manufacturing, energy materials, catalysis,
and other fields. However, due to the common coexistence of Sc with
light and heavy REEs, which exhibit high similarities in ionic radius,
valence state, and coordination chemistry, conventional spectrophotometric
methods suffer from poor selectivity, making accurate quantification
of Sc 3+ in complex matrices difficult. In this study, we
present a label-free ion sensing platform based on silicon nanowire-modified
glass micropipettes (SiNWs@GMP). By incorporating the Sc-1 DNA recognition
unit, the platform achieves highly sensitive and selective detection
of Sc 3+ as well as sequential discrimination between light
and heavy REEs. The three-dimensional porous SiNWs network inside
the GMP provides abundant immobilization sites for Sc-1 DNA. Under
an applied electric field, the specific binding between Sc 3+ and Sc-1 DNA modulates ion transport within the channel, generating
measurable changes in ionic current. The constructed sensor exhibits
a detection concentration range for Sc 3+ from 1 pM to 10 5 pM and a detection limit for Sc 3+ as low as 1
pM, which can effectively distinguish Sc 3+ from light REEs.
Meanwhile, the use of EDTA to selectively suppress interference from
coexisting heavy REEs further verifies the high selectivity of Sc-1
DNA. This platform demonstrates good stability, repeatability, and
reliability in aqueous environments, highlighting its potential for
applications in environmental monitoring and REEs analysis.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2026
·
IF 8.3
Jinlan Yang,Habib Khan,Chushi Chen,Meng Wang,Lina Xiu,Li Yang
Paper-based analytical devices (PADs) have revolutionized environmental monitoring, food safety and disease diagnosis due to their inherent portability, simplicity, and cost-efficiency. Among these, distance-based PADs enable instrument-free quantitative detection by translating target concentration into measurable flow distance. Stimuli-responsive hydrogels, whose viscosity can be altered by target-triggered sol-gel transitions, are widely used in distance-based PADs, among which click-chemistry hydrogels stand out by virtue of their efficient and stable covalent bonding. Such stable covalent networks provide click hydrogels with strong anti-swelling and anti-degradation properties, crucial for reliable performance in on-site environments. In this study, we present a novel distance-based PAD approach that integrates target-induced click hydrogels, establishing a highly stable, versatile, and sensitive platform for multi-analyte detection. This innovative PAD makes use of copper-catalyzed azide-alkyne cycloaddition click chemistry to craft hydrogels from polyethylene glycol derivatives. Notably, specific target analytes like Cu²⁺, ascorbic acid, alkaline phosphatase, and pyrophosphate finely modulate the hydrogel crosslinking degree, causing noticeable changes in its viscosity. These viscosity variations are then translated into measurable flow distances on pH test papers, providing a direct and quantitative visual readout without the need for complex instrumentation or extensive operation. The entire detection process, from sample loading to result readout, can be accomplished within approximately 5 min, demonstrating the rapid analysis capability of this approach. This work offers stable, rapid, sensitive, and cost-effective multi-target detection, significantly advancing instrument-free PAD technology and expanding the scope of versatile analyte detection.
✓ 已验证
产品关联
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2026
·
IF 5.2
Guoyong Liu,Yanrui Xie,Yanzhen Cao,Yingying Jing
Under the catalysis of MnO 2 , TBHQ can react with Cys to generate fluorescent CDs. • A fluorescence turn-on sensor for detection of TBHQ is proposed based on in-situ formation of fluorescent CDs. • This sensor is capable of quantitatively measuring the concentration of TBHQ in edible oils. Excessive intake of the food additive tert -butylhydroquinone (TBHQ) causes potential hazards to the human body. Designing an easy-to-fabricate and efficient TBHQ sensor is of great research significance. We found that in the presence of MnO 2 , TBHQ can react with cysteine (Cys) to generate fluorescent carbon dots (CDs). Inspired by this simple fluorogenic reaction, a turn-on sensor for TBHQ detection is proposed based on in-situ formation of fluorescent CDs. The sensor offers a linear range of 1–200 μM and a detection limit as low as 0.06 μM. Due to its simple reaction precursors and unambiguous reaction mechanism, this sensor demonstrates good practicability for TBHQ measurement in edible oils. This fluorescence turn-on in-situ sensor, which does not require pre-synthesized materials, offers considerable potential for on-site detection of TBHQ. Download: Download high-res image (122KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
Journal of Environmental Chemical Engineering
·
2026
·Vol. 14
·期 5
·124230
·
IF 7.5
Xiao Wu,Linye Li,Yongxiang Yi,Qingqing Qin,Zhu Luo,Shuhao Qin
To overcome the technical bottleneck caused by imperfect conductive networks in films, which limits separation selectivity, this study employed a novel polymer - amide - sulfonic acid gradient coating strategy to achieve near-individual dispersion of high-purity carbon nanotubes (CNT). On this basis, a conductive carbon nanotube@polyvinylidene fluoride (CNT@PVDF) film was prepared via phase separation, showing a conductivity of up to 4.99 S·m –1 . By regulating the CNT slurry concentration to reduce mass-transfer resistance during phase separation, and through the combined mechanisms of Donnan rejection, the electroosmotic flow effect, and physical filtration, the separation performance of the film was significantly improved. Under the optimal CNT content (6 wt%) and an applied voltage of –3 V, the film showed a pure water flux of 134.52 L·m –2 ·h –1 , with rejection of 98.13% for Bovine Serum Albumin (BSA) and a selectivity factor of 84.7 for Congo red/sodium chloride (CR/NaCl), exceeding currently reported values. Furthermore, after 10 cycles, the film retained about 98% of its CR/NaCl selectivity factor and showed a flux recovery rate of 96.2% compared with the initial use, indicating favorable antifouling ability and long-term operational stability. These results demonstrate the considerable potential of high-purity CNT slurries in constructing conductive separation films and provide a new strategy to address the trade - off between permeability and selectivity in dye/salt separation processes.
✓ 已验证
产品关联
DOI
高影响因子
Surfaces and Interfaces
·
2026
·
IF 6
Jitong Ren,Lei Gu,Zhuoya Chen,Lei Li,Yanyan Guo,Jiang Zhao
Flexible capacitive humidity sensors frequently suffer from active material leaching, weak interfacial adhesion, and complex electrode fabrication processes. To address these challenges, a lithium chloride-enhanced laser-induced graphene (LiCl/LIG) composite electrode on a polyimide (PI) substrate is obtained through a one-step, in-situ laser direct writing approach. The synthesized three-dimensional (3D) interconnected porous LIG framework provides abundant anchoring sites that spatially confine the highly hygroscopic LiCl. This architecture effectively mitigates deliquescence-driven leaching while ensuring a highly conductive signal transmission network. Consequently, the optimized sensor exhibits an ultrahigh sensitivity of 35,373.8 % (Δ C / C 0 ) across a broad working range (11–97 % RH). The device also demonstrates rapid response and recovery times (76 s and 110 s, respectively), alongside low hysteresis (5.87 %). The practical utility of the sensor is validated through high-fidelity continuous respiratory monitoring and non-contact spatial sensing applications. Furthermore, the sensor is seamlessly integrated into a portable, fully wireless smart diaper monitoring system capable of real-time moisture alerts, demonstrating substantial promise for scalable wearable electronics and intelligent Internet of Things (IoT) healthcare systems. Download: Download high-res image (430KB) Download: Download full-size image
✓ 已验证
产品关联
DOI
高影响因子
COLLOIDS AND SURFACES B-BIOINTERFACES
·
2026
·
IF 5.9
Peiyao An,Mengxiao Li,Shanshan Zhang,Di Lian,Chuqi Li,Chuan Wang,Miao Yu,Duo Wang,Lingyi Kong,Jun Ren,Yue Li,Haiyan Wang,Xin Yang,Zhenlin Wu
LC sensing platform based on WGM laser is developed for the AD-related biomarker Aβ42 detection. • The sensor sensitivity is approximately 0.003 nm/pg/mL, and the LOD is 3 pg/mL. • RNA aptamer is used as recognition probes to enhance the specificity of the biosensing platform. • The combination of RNA aptamer and Aβ42 causes RI changes, resulting in WGM spectral shifts. • The structure design provides an ideal sensing platform for detecting biomedical samples. Alzheimer's disease (AD) is an irreversible and progressively worsening neurodegenerative disorder. Amyloid beta (Aβ42) plays a crucial role in the early diagnosis of this disease. However, the concentration of Aβ42 in the blood is extremely low, which poses a challenge for Aβ42 detection. Herein, a liquid crystal (LC) biosensing platform based on whispering gallery mode (WGM) laser was developed for rapid and real-time monitoring of the AD-related biomarker Aβ42. The LC microcavities were functionally modified using cetyltrimethyl ammonium bromide (CTAB) and RNA aptamers. Based on this, the quantitative monitoring mechanism of Aβ42 was analyzed, stemming from the interaction between the negatively charged RNA aptamer and CTAB, leading to the reorientation of LC molecules. This alters the refractive index distribution within the microcavity, thereby enabling the shift of the WGM spectrum. The dynamic changes of molecular orientation in the LC microcavity were monitored by polarization optical microscopy and spectral analysis. The experimental results showed that the total shifts in the resonance spectrum were directly proportional to the concentration of Aβ42 within the range of 0–1000 pg/mL. The sensitivity of the sensor is 0.003 nm/pg/mL. The experiment further confirmed the practicability of this sensor in the mouse serum. The sensor is inexpensive, easy to manufacture and fast and it is potentially useful for AD-related biomarker screening after further validation.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SEPARATION AND PURIFICATION TECHNOLOGY
·
2026
·
IF 9.1
Yingzhen Wu,Enshen Shi,Haojie Song,Lu Li,Chungang Xie,Yongjiang Yu,Yanan Liu,Zhongyi Jiang
Nanofiltration membranes possess great potential in ion separation, meanwhile, the pore and surface properties determining membrane permeance and selectivity, should be designed and regulated. Herein, we utilized reactive ionic liquid (1-aminoethyl-3-methylimidazolium tetrafluoroborate, AMIM-BF 4 ) simultaneously as aqueous phase additive and surface modifier to regulate pore and surface properties for fast and efficient Li + /Mg 2+ separation. AMIM-BF 4 was added in aqueous phase to undergo a competitive interfacial polymerization with polyethyleneimine (PEI), effectively increasing the average pore size of the membrane. Then, amino group in AMIM-BF 4 could react with the unreacted acyl chloride groups to modify membrane surface, increasing its positive charge and hydrophilicity. Accordingly, the membrane possessed high water permeance of 33.3 L m −2 h −1 bar −1 with MgCl 2 rejection rate of 98.9%, and separation factor of 22.7 for the mixed solution with magnesium-to‑lithium ratio (MLR) of 50:1. Meanwhile, during the 168-h continuous cross-flow test, the rejection rate for MgCl 2 remained above 98.1% with stable water permeance. Moreover, through the three-stage nanofiltration experiment, the membrane could reduce the MLR of simulated salt lake brine with 2000 ppm from 50:1 to only 0.02:1, demonstrating its potential for efficient lithium enrichment from complex brine.
✓ 已验证
产品关联
DOI
高影响因子
ADVANCED FUNCTIONAL MATERIALS
·
2026
·Vol. 36
·期 61
·e76959
·
IF 19.9
Haoxuan Jiao,Xin Peng,Xin Liu,Jianqiang Chen,Hao Tian,Yuzhi Fang,He Zhao,Xinyu Huang,Yahui Xue,Yuegang Zhang
Recent advancements in nanofluidic memristors have drawn significant attention owing to their capability to mimic neuromorphic functions observed in biological neural systems. However, challenges remain in structure miniaturization and achieving ion-specific and complex neuromorphic functions. Hydrogels, with excellent ionic conductivity and dynamic porous structures, establish an ideal ionic transport environment. Moreover, their diverse chemical functionalities enable pH- or electric field-modulated ion selectivity. Here, a miniaturized on-chip nanofluidic memristor based on asymmetrically nanoconfined polyacrylic acid (PAA) hydrogel is reported. The device exhibits distinct transport behaviors depending on ion species, attributed to different interaction strengths between cations and carboxyl groups. Through diverse electrical modulations, neuromorphic functionalities including short-term plasticity, long-term plasticity, and spike-timing-dependent plasticity are demonstrated. Beyond electrical modulation, the device can also be chemically modulated. By regulating the pH of the solution and hence modulating the cation–hydrogel interactions in the nanofluidic channel, the device can achieve reconfigurable synaptic functions. Furthermore, by integrating two devices into series and parallel circuits, the “synaptic integration” function of biological neurons is mimicked, enabling fundamental “AND” and “OR” logic operations. This work presents a nanofluidic platform achieving ion-specificity, electrical control, chemical reconfiguration, and biomimetic integration, laying the groundwork for complex brain-like computing.
✓ 已验证
产品关联
DOI
高影响因子
International Journal of Analytical Chemistry
·
2026
·Vol. 2026
·期 1
·3877339
·
IF 2.8
Feifei Liu,Jing Li,Wenna Jiang,Jing Pang,Shuo An,Yue Shi,Li Ren
Human epidermal growth factor receptor 2 (HER2) is a critical biomarker for targeted therapy of gastric cancer. Tissue-based HER2 testing via immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH) remains the clinical gold standard, while serum HER2 represents a potential complementary circulating biomarker for disease monitoring. However, conventional serum HER2 assays often suffer from limited sensitivity. Herein, we develop a highly sensitive fluorescence assay for serum HER2 detection using nonlinear hybridization chain reaction (NHCR) coupled with a HER2-specific aptamer (HB5). Unlike linear hybridization chain reaction (HCR), NHCR enables branching-mediated exponential amplification, in which each trigger initiates multiple independent HCR cascades, leading to nonlinear signal growth. The method exhibited a good linear relationship ( R 2 = 0.993) in the HER2 concentration range of 0.5–90 ng·mL −1 , with a detection limit as low as 38 pg·mL −1 . The sensor demonstrated excellent specificity for HER2, good reproducibility, and reliable stability. Clinical serum sample detection results indicated that the method was highly correlated with the clinically commonly used chemiluminescence immunoassay (CLIA), with spiked recoveries ranging from 95.4% to 109.6%. The NHCR-based fluorescent detection strategy established in this study provides a new tool for accurate and noninvasive detection of serum HER2, featuring simple operation and controllable cost.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Small
·
2026
·
IF 11.8
Lixun Zhang,Xuewu Shen,Han Hu,Shengyin Tang,Sunny Jiang,Yuntao Guan
Microcystin contamination caused by harmful cyanobacterial blooms is a growing global challenge for water safety. Here we reported a self-assembled living microreactor that encapsulated microcystin-degrading bacteria within a biochar-reinforced double-network hydrogel, enabling integrated molecular sieving, adsorption, and enzymatic degradation. The system exhibited size- and charge-selective removal of microcystin over coexisting organic matters, while maintaining high degradation efficiency under harsh stress conditions, including pH (5−9), inorganic ions (10−200 mg/L), and natural organic matters (5−20 mg/L). The microreactor demonstrated excellent mechanical stability, negligible cell leakage, and high bioactivity, and achieved nearly complete removal of microcystin-LR during five repeated operation cycles and continuous biofiltration in environmental water, confirming its scalable application potential. Mechanistic investigations revealed a cascade process involving shell-confined molecular sieving, adsorption-mediated toxin enrichment on biochar, and localized biodegradation within the living core. This work establishes a generalizable design paradigm for programmable living materials, offering new opportunities for selective biodegradation and remediation in complex aqueous systems.
✓ 已验证
产品关联
DOI
PubMed
高影响因子
危险品化学品经营许可证（带存储）