Nano Energy
·
2026
·
IF 16.7
Hanxiao Zhang,Weihui Li,Yonglan Huang,Can Wang,Hui Cai,Jiulong Sha
Triple-layer hydrogel MEG builds sustained ionic gradient via dual ion-transport synergy. • Device outputs 0.47 V at 10% RH and 0.72 V at 100% RH, showing excellent adaptability. • At 80% RH, the device outputs 0.895 V and 201.8 µA cm ⁻2 for over 200 h. • This device enables self-powered hydrogen production. Moisture-enabled generators (MEGs) harvest electricity from atmospheric humidity, yet their performance declines under extremely low or high humidity owing to inadequate or excessive moisture uptake. Inspired by ion-selective migration in electric eels, an integrated triple-layer hydrogel-based MEG (QLT-MEG) is developed. It features a central hygroscopic layer (LGP) sandwiched between anion- (QP) and cation-selective (TPP) layers. A water gradient from the LGP drives intrinsic ion (Cl − /H + ) diffusion in the side layers, while the side layers selectively and directionally guide reservoir ions (Cl − /Li + ) from the LGP. This dual-ion-transport synergy builds a sustained concentration gradient for efficient power generation. A single QLT-MEG delivers a high output of 0.895 V and 201.87 µA cm −2 at 80% relative humidity (RH). Using an Al electrode boosts the performance to 1.38 V and 1.41 mA, respectively. Remarkably, it retains substantial outputs of 0.47 V and 29.22 µA cm −2 at 10% RH, and 0.72 V with 154.31 µA cm −2 at 100% RH, demonstrating exceptional humidity adaptability. Experimental and DFT/MD analyses confirm sustained water gradient and ion-selective migration as the underlying mechanisms for its high performance. Furthermore, integrated QLT-MEG arrays reliably power small electronics and drive water electrolysis, showcasing their potential for flexible, scalable off-grid power solutions. Download: Download high-res image (225KB) Download: Download full-size image
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Foods
·
2026
·Vol. 15
·期 14
·2420
·
IF 6
Junren Zhao,Yugang Ji,Wenjing Tao,Chun Wang,Zhimei Tang,Yujia Shi,Huiyun Zhang
Chlorogenic acid (CA) exhibits robust lipid antioxidant activity within meat matrices. However, excess CA generates quinones that alter and damage porcine myofibrillar protein (MP). This study investigated the restorative effects of chitosan (CS) on MPs suffering from CA-induced oxidative damage. Three CA concentrations (0, 50, 100 μmol/g protein) and five CS dosages (0.125–1.0 g/g protein) were used to evaluate conformation, turbidity, surface hydrophobicity, solubility, emulsification, rheology, and gel properties. CA-oxidative damage to MP triggered protein unfolding, thiol depletion and aggregation, greatly lowering solubility, emulsifying capacity, viscoelasticity and water retention. CS exerted biphasic effects on turbidity, surface hydrophobicity, tertiary structure, and solubility only under severe CA-induced oxidative modification (100 μmol/g CA): low-to-medium CS aggravated adverse changes, while 1.0 g/g CS partially reversed such damage. For conformational, emulsion and gel parameters, CS consistently alleviated structural disorder caused by CA-induced oxidative damage across all treatments, with 1.0 g/g CS optimally mitigating α-helix loss and uneven emulsion droplets. Significant CA × CS interactions were detected for conformation, turbidity, surface hydrophobicity, solubility, emulsification and rheology (p< 0.001). Gel strength, water-holding capacity and water distribution exhibited non-significant interactions (p> 0.05), revealing independent additive effects of CA and CS on gel networks. Overall, high-dose CS partially ameliorates structural and functional defects of MP caused by CA-induced oxidative damage, which provides theoretical support for the combined application of polyphenols and polysaccharides in meat protein regulation.
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ADVANCED FUNCTIONAL MATERIALS
·
2026
·
IF 19.9
Quanli Qian,Kaiying Zhao,Mengjiao Diwu,Jiarui Cui,Ziheng Zhang,Lijuan Wang,Cheolmin Park,Yan Cheng,Jianying Huang,Yuekun Lai,Tianxue Zhu
Ambient humidity represents a ubiquitous and renewable energy source for next-generation moisture-driven energy harvesting, yet achieving stable and long-term output remains a formidable challenge for practical use in wearable electronics and environmental sensing. Here, we report a high-performance moisture-driven energy generator (MEG) that exploits a gradient bilayer electrospun membrane to realize directional moisture transport, resulting in efficient and long-term stable electricity generation. The device integrates two polyacrylonitrile/sulfonated polyaniline (PAN/S‑PANI) nanofiber layers with different porous structure, an electrostatic-flocked carbon cloth electrode, and an aluminum electrode. Fixed anionic sites in S‑PANI facilitate cation (e.g., Li + , H + ) transport while suppressing anion (Cl − ) migration, whereas the flocked electrodes promote enhanced water evaporation and directional moisture transport. Benefiting from the rational design, the MEG delivers an output of up to 1.1 V and 3.3 mA . cm −2 under 45°C and >80% relative humidity, representing state-of-the-art performance. Remarkably, after being stored for 180 days, the device still maintained an output voltage of ∼0.7 V and a current above 450 µA, which was sufficient to power calculators and smartwatches. This work offers a promising pathway toward durable, self-powered, and flexible energy systems.
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ACS Sustainable Chemistry & Engineering
·
2026
·
IF 7.6
Zhou Deng,Zicheng Wu,Yaxin Chen,Yanhong Zhou,Manqi Cheng,Xiang Li,Yu Feng,Shiyu Lu,Zhiwei Yi,Guangya Zhang
Efficient deployment of carbonic anhydrase (CA) in direct air capture (DAC) is constrained by the lack of enzyme durability under alkaline, chemically complex, and long-term operating conditions. A carrier-free self-immobilization strategy based on encapsulin-mediated intracellular assembly was proposed to address these challenges. The fusion of Sulphurihydrogenibium azorense carbonic anhydrase (SazCA) with the encapsulin EncMh from Mycolicibacterium hassiacum enables spontaneous self-assembly into supramolecular particles during expression in host cells, allowing high-yield production and low-energy recovery by simple centrifugation. The resulting SazCA-EncMh assemblies exhibit high thermal stability and broad tolerance toward alkaline and ion-rich environments. Notably, their supramolecular state can be reversibly switched between nano- and microscale assemblies by pH modulation without loss of catalytic activity over multiple cycles. Under DAC, free SazCA-EncMh significantly enhances long-term Chlorella cultivation over 21 days, indicating sustained extracellular catalytic function and improved inorganic carbon availability. In addition, SazCA-EncMh exbibits improved stability relative to ferritin-based assemblies in representative DAC absorbents, including amino acid salts and tertiary amines. Overall, encapsulin-enabled self-immobilization offers a practical and scalable strategy for stabilizing CA under DAC-relevant conditions, supporting its integration into biological and hybrid carbon capture systems.
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Science Signaling
·
2026
·Vol. 19
·期 948
·
IF 7
Qian Zhang,Yuedan Zhu,Yi Chen,Wenhao Hou,Aolong Sun,La Yan,Xingzhu Liu,Yu Yuan,Chaoxin Gao,Junfeng Xie,Rui Zhang,Haiyang Chen
Aging impairs intestinal stem cell (ISC) function, disrupting epithelial homeostasis and regenerative repair. Loss of ISC quiescence promotes intestinal dysfunction and contributes to organismal aging. Here, we report an epitranscriptomic mechanism through which a decrease in adenosine-to-inosine (A-to-I) RNA editing by the adenosine deaminase ADAR in ISCs during aging disrupts a conserved signaling axis that maintains ISC quiescence. In Drosophila melanogaster , ISC-specific loss of dADAR triggered hyperproliferation and tissue aging, whereas dADAR overexpression reduced age-related gut dysfunction and extended life span. Intestinal injury induced a decrease in dADAR, which was necessary for tissue regeneration, and in the zinc finger protein dZn72D, which stabilized dADAR to support intestinal homeostasis during aging. dADAR edited transcripts encoding the RNA binding protein Pumilio (dPUM) to generate an isoform that inhibited translation of two components of the mitogen-activated protein kinase (MAPK), dEGFR and dERK, thereby maintaining ISC quiescence. The abundance of ADAR2 and of the dZn72D ortholog ZFR decreased in human colonic crypts with aging and in mouse colon after injury, suggesting that attenuation of ADAR activity may play a conserved role in ISC aging and in facilitating colonic regeneration. Our work identifies a conserved mechanism of epitranscriptomic regulation that safeguards tissues and the decay of ADAR-mediated RNA editing as a form of age-related epigenetic information loss that disrupts ISC homeostasis.
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JOURNAL OF CATALYSIS
·
2026
·
IF 6
Haoling Yang,Qi Zhang,Kunyu Xu,Guang Wang,Yiqi Pan,Licheng Lu,Qi Mao,Zihao Yang,Zhaoxia Dong
Enhancing the catalytic activity of germanium-based catalysts can reduce their required dosage and effectively lower the production cost of high-end polyester. Numerous studies have demonstrated that variations in catalyst crystal structures exert a decisive influence on their activity, selectivity, and stability. Based on this observation, the adsorption energy of tetragonal germanium dioxide (GeO 2 ) on polyester reactants was calculated through molecular simulations, revealing that tetragonal GeO 2 possesses a stronger adsorption capacity for polyester reactants than hexagonal GeO 2 . Subsequently, a novel low-temperature hydrothermal approach was developed to synthesize small-sized tetragonal GeO 2 . This approach reduces the crystal transition temperature from 1000 °C to 240 °C, thereby significantly lowering the energy consumption of the process. The catalytic activities of GeO 2 with different crystal systems were analyzed using kinetic studies. Polyethylene terephthalate (PET) samples synthesized from GeO 2 catalysts with different crystal systems were subsequently characterized. The results indicate that tetragonal GeO 2 exhibits superior catalytic activity, and the resulting PET polyester displays improved color, transparency, and thermal stability. These findings confirm the feasibility of enhancing the catalytic performance of germanium-based catalyst systems through crystal transformation. This work provides new insights and possibilities for the future development of high-performance polyester products and efficient germanium-based polyester catalysts.
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ACS Nano
·
2026
·
IF 16
Xi Wang,Yifan Guo,Qixiang Zhang,Tianyun Jing,Zhe Li,Kai Chen,Naijia Zhao,Zhen Zhang,Lei Jiang
Constructing ion channels to mimic the diode characteristics of protein channels in living organisms is crucial for realizing ionic signal transmission and brain-like computing with logical capabilities. Nonetheless, it is challenging to achieve unidirectional transport of protons due to their high mobility and small volume for the dimensions of most nanochannels (>0.5 nm). Herein, drawing inspiration from the architecture of human skin, composed of dry epidermis and wet dermis that features an inherent electrochemical ion gradient and asymmetric transport routes, we present a quasi-solid-state heterogeneous ionic diode membrane by integrating two layers of poly(vinyl alcohol)-based hydrogels, which synergize the intrinsic electrochemical gradient with asymmetric structure and functional groups. Such membranes exhibit a remarkable proton rectification ratio of 47, which can be further amplified to 65 in response to external pressure, representing the state-of-the-art. Experimental and theoretical results reveal that the difference in proton migration energy barriers at the heterogeneous membrane interface is the key reason for the unidirectional proton transport behavior. With this membrane, we have successfully simulated the signal transmission and computation between neuronal synapses by constructing voltage-adaptive ionic transistor devices. This work demonstrates a general route for designing a high-rectifying proton diode, enabling advanced functionalities in biosensing and neuromorphic computing.
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npj Science of Food
·
2026
·
IF 9.7
Chen Yu,Pan Yi,Hu Yu-Ting,Yang Le-Ying,Wang Lin-Ru,Sha Xiao-Mei,Tu Zong-Cai
Neutral protease and gum arabic (GA) were combined to enhance foaming ability (FA) and foaming stability (FS) of fish gelatin. Meanwhile, structural changes of pure, single-modified and combined-modified fish gelatins were evaluated in detail to investigate the mechanism. FA and FS of combined-modified fish gelatin were boosted to the maximum of 158% and 55%, respectively. The enzymolysis enhanced the surface hydrophobicity (increased by 40%) and destroyed the microstructure. On the basis, hydrogen bond and electrostatic forces of combined-modified fish gelatin were strengthened by GA, which elevated viscosity and interfacial protein adsorption content (6 mg/g), enhancing FS and FA. The redshift of amide I and II wavenumbers indicated more stable secondary structure of combined-modified fish gelatin, reflected in the SEM-verified denser foam. The underlying mechanism for improving foaming properties of fish gelatin was related to the opened structure by neutral protease and further noncovalent interaction by GA. New insights for the development of sustainable foaming agents were provided by these findings.
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Current Protocols
·
2025
·Vol. 5
·期 10
·e70241
·
IF 2.2
Yiming Zhao,Jingjun Hong
Chromatin remodeling is a process of regulating gene expression levels by altering chromatin structure, facilitated by chromatin remodeling factors. ISWI (Imitation SWItch), a type of chromatin remodeling factor, plays a crucial role in epigenetic regulatory processes, such as cell differentiation and development. It primarily achieves remodeling effects by promoting the direct sliding of nucleosomes and their relocation on DNA. To study the function and structural characteristics of ISWI, this basic protocol describes a simple and rapid procedure for the large-scale expression and purification of soluble Ct ISWI 77-1038 and Ct ATPase 77-722 proteins in Escherichia coli ( E. coli ). The procedure provides high yields (∼20 mg) and is followed by in vitro measurement of ATP hydrolysis activity. © 2025 Wiley Periodicals LLC. Basic Protocol : Expression, purification, and ATP hydrolysis activity measurement of Ct ISWI and Ct ATPase
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FOOD CHEMISTRY
·
2025
·
IF 9.8
Xiang Li,Bo Wang,Wenwen Hou,Jie Tang,Hongbin Lin,Junqiang Lian,Qian Liu,Mingfeng Xu,Yuan Ma,Dong Yu,Dong Zhang,Jiaxin Chen
The effects of sucrose ester concentrations (0.1, 1.0 and 10 mM) on myofibrillar protein emulsion gel at 0.3 and 0.6 M ionic strengths were investigated. At 0.3 M ionic strength, an elevated sucrose ester concentration increased the droplet size (from 31.86 to 55.97 μm) and absolute zeta potential (from 29.60 to 47.57 mV). Furthermore, it promoted protein folding at 0.3 M ionic strength but induced unfolding at 0.6 M. Elevated sucrose ester concentration reduced the α-helix content (from 45 % to 20 %) at 0.6 M ionic strength. Molecular dynamics simulations showed that high ionic strength promoted stable binding between sucrose ester and myosin. Moreover, higher sucrose ester concentrations weakened gels, increased free water content and enhanced viscous dominance in rheology. These findings provided meaningful insights into the mechanism of the surfactant-mediated formation of myofibrillar protein emulsion gels under varying ionic strengths.
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CHEMICAL ENGINEERING JOURNAL
·
2025
·
IF 13.2
Gangli Zhao,Fangzhou Li,Linglan Guo,Dingyun Zhang,Haotian Luo,Jiaxing Huo,Zechao Han,Peicheng Han,Qiaolin Gu,Ran Tang,Yanjie Su,Feng Zhan,Limin Zhu,Daozhi Shen
Harvesting energy from ubiquitous moisture in air from the interaction with hygroscopic materials shows great promise in green energy and portable power for off-grid electronics. However, the lack of efficient materials design and tunable ions migration result in the short duration time and low output. Here, we propose an efficient and durable moisture electric generator (MEG) design by adding cellulose nanofibers into ionic hydrogel where sodium ions act as anchors through electrostatic interactions to prevent the output collapse. The accessible nanochannels in cellulose nanofiber clusters provide the additional ion migration pathways for efficient electricity generation. A single MEG device can yield open-circuit voltage of 0.8 V and maintain >95 % of its initial output even after ∼1000 h of continuous operation. This maintaining period exceeds the operating time of similar devices by a factor of 10–60. Importantly, this long duration is purely originated from the intrinsic moisture electricity generation since the utilization of inert electrodes in MEGs eliminates the potential chemical reactions between water and the electrodes. Our work presents a strategy for designing intrinsically sustainable MEGs with enhanced output and paves ways for achieving substantial breakthroughs for moisture power generation.
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CARBOHYDRATE POLYMERS
·
2025
·
IF 12.5
Jinyu Chen,Siyang Wang,Zhirui Ji,Xianji Yi,Jiaqi Guo,Guofeng Jin,Zijian Wu
For purpose of overcoming the negative impact of high-dose phenols on meat quality, xanthan gum (XG), a natural anionic polysaccharide, was employed to prevent the undesirable interaction between myofibrillar protein (MP) and gallic acid (GA, 150 μmol/g) and ameliorate the gel and emulsification characteristics of MP. XG dose-dependently alleviated the structural damage of MP caused by GA and reduced protein aggregation, manifested as the decrease in surface hydrophobicity, turbidity and aggregate size ( p < 0.05) and increase in α-helix content and intrinsic fluorescence. As a result, more proteins participated in establishing an ordered cross-linked network, favoring the entrapment of immobilized water and imparting the gel with improved rheological properties and gel strength (from 2.2 N·mm to 3.1–5.5 N·mm) and a decreased cooking loss (from 13.6 % to 3.2 %–7.7 %). In addition, the presence of XG reduced oil–water interfacial tension of MP, promoting uniform distribution of emulsion droplets in a smaller size. The emulsifying activity and stability increased from 6.5 m 2 /g to 8.1–8.4 m 2 /g, and 41.5 % to 81.2 %–93.2 %, respectively, and the creaming index decreased from 52 % to 0 %–24 %. The multiple light scattering and microrheology results further demonstrated the enhancement of emulsion stability. The competition mechanism of XG, along with its hydrophilicity, electronegativity and viscosity, collectively contributed to the improvement of gel and emulsion quality. Our paper exploited the potential of dual application of polysaccharides and polyphenols in meat products for simultaneously reducing protein oxidation and quality deterioration.
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危险品化学品经营许可证（带存储）