MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Jijun Guan,Liwei Wang,Fugang Xu,Guangran Ma
Ratiometric electrochemical probes are vital for reliable sensing but often suffer from complex preparation, reference molecule leakage, and single function. To address these limitations, this study reports a flower-like Cu-doped zeolite imidazolate framework (Zn 0.5 /Cu 0.5 /Co-ZIF) prepared at room temperature via simple stirring. This material acts as both an electrode material and a robust ratiometric probe for detecting catechol (CC) and acetaminophen (AP). Compared with pristine Zn/Co-ZIF, Cu doping confers several advantages: transforming lamellar Zn/Co-ZIF into a flower-like structure for enhanced electron and mass transfer; significantly improving redox current of CC/AP for high sensitivity; and generating a stable Cu-based redox signal as an internal reference, improving accuracy. The sensor achieved wide linear ranges (CC: 0.5–150 μM; AP: 0.2–300 μM) and low detection limits (CC: 0.12 μM; AP: 0.04 μM) for determination of phenol compounds. Compared to single-signal assay, the ratiometric approach showed lower RSDs and superior linear correlations. The sensor also achieved satisfactory simultaneous detection of CC and AP, along with accurate quantification in lake water samples. This work presents a facile strategy for a MOF based reference probe, offering a promising platform for stable and accurate ratiometric electrochemical sensors.
研究领域:
生物传感
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分析化学
·
纳米材料
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环境监测
·
电化学检测
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2019
·Vol. 166
·期 15
·H777
·
IF 3.12
Wenwen Xu,Yonghong Sun,Cuimin Shao,Jianguo Wang
ATP, ADP, and cytidine triphosphate (CTP) are common sources of energy for various cellular activities. Therefore, a method that efficiently measures ATP, ADP, and CTP levels is urgently needed. In unbuffered solution, ATP, ADP, and CTP were observed to cause a new cathodic peak at a positive potential during benzoquinone (BQ) reduction. The hydrolysis of ATP, ADP, and CTP generated additional proton donors, which provided numerous protons for the reduction of BQ and formation of a large new cathodic peak. The peak current difference between the peaks caused by ATP, ADP, and CTP before and after hydrolysis was linear to the ATP, ADP, and CTP concentrations but independent of the BQ concentration. An electrochemical method for the detection of ATP, ADP, and CTP was developed using a bare glassy carbon electrode. The proposed method showed good selectivity for the detection of ATP samples.
研究领域:
生物化学
·
分析化学
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产品关联
DOI
高影响因子
Food Analytical Methods
·
2018
·Vol. 11
·期 12
·3380-3390
·
IF 2.245
Tang Jing,Mao Yueyuan,Guo Jiahao,Li Zirong,Zhang Chen,Jin Baokang
A glassy carbon electrode (GCE) was modified with eosin Y that was electrodeposited on GCE via continuous cycling between − 1.6 and 1.5 V (vs Ag/AgCl). This electrode was characterized by scanning electron microscopy and electrochemical impedance spectra. The resulting electrode exhibited excellent electrocatalytic activity toward the oxidation of butylated hydroxyanisole (BHA) and tert-butyl hydroquinone (TBH 2 Q); in addition, the oxidation products of BHA and TBH 2 Q were found to be the same, which was studied by CV and in situ FT-IR spectroelectrochemistry. Under the optimized condition, the oxidation peak currents were linear to BHA/TBH 2 Q in the range from 0.10 to 7.00 μg mL −1 with the detection limits of 0.01 μg mL −1 (S/N = 3) for BHA and 0.015 μg mL −1 (S/N = 3) for TBH 2 Q, respectively. Moreover, the reproducibility and repeatability of the electrode were determined. The proposed method was successfully applied in the simultaneous determination of BHA and TBH 2 Q in several edible oil samples, and satisfactory results when compared with those obtained using high-performance liquid chromatography.
研究领域:
食品科学
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分析化学
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DOI
高影响因子
MATERIALS RESEARCH BULLETIN
·
2024
·
IF 5.3
Ji Zhang,Chenguang Yang,Yan Xu
Hierarchical electrochemical sensors with specific recognition function have been widely applied for trace amounts detection of metal ions, showing great significance for monitoring environmental quality. Herein, a novel flower-like ytterbium benzene-1,3,5-tricarboxylate metal-organic framework (Yb-MOF-1) was prepared by a one-step solvothermal method, which was then cast on a glassy carbon electrode to construct a sensing platform. Compared to the traditional rod-like Yb-MOF-2 prepared at a lower pH (pH = 4.26), the Yb-MOF-1 assembled from ultrathin nanosheets has a large surface area (462.356 m²/g), showing simultaneous electrochemical detection performance towards Cd 2+ , Pb 2+ and Cu 2+ in aqueous solution with detection limits of 9.22, 1.69, 15.15 nM, respectively. The experimental results demonstrate its good anti-interference and repeatability. The reliable practical application of Yb-MOF-1 for Cd 2+ , Pb 2+ and Cu 2+ detection in real water samples shows good recovery rates ranging from 95.8 % to 103.5 %, proving the effective strategy in exploring efficient electrochemical sensing materials.
研究领域:
环境科学
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材料科学
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分析化学
✓ 已验证
产品关联
DOI
高影响因子
FOOD CHEMISTRY
·
2024
·
IF 8.5
Jiani Zhang,Xiaohui Guo,Jian Zhang,Xiaobing Guo,Yuying Xu,Lijuan Chen
Phoxim, extensively utilized in agriculture as an organothiophosphate insecticide, has the potential to cause neurotoxicity and pose human health hazards. In this study, an electrochemical enzyme biosensor based on Ti 3 C 2 MXene/MoS 2 @AuNPs/AChE was constructed for the sensitive detection of phoxim. The two-dimensional multilayer structure of Ti 3 C 2 MXene provides a robust framework for MoS 2 , leading to an expansion of the specific surface area and effectively preventing re-stacking of Ti 3 C 2 MXene. Additionally, the synergistic effect of self-reduced grown AuNPs with MoS 2 further improves the electrical conductivity of the composites, while the robust framework provides a favorable microenvironment for immobilization of enzyme molecules. Ti 3 C 2 MXene/MoS 2 @AuNPs electrochemical enzyme sensor showed a significant response to phoxim in the range of 1 × 10 −13 M to 1 × 10 −7 M with a detection limit of 5.29 × 10 −15 M. Moreover, the sensor demonstrated excellent repeatability, reproducibility, and stability, thereby showing its promising potential for real sample detection.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2020
·
IF 7.1
Yu-Feng Sun,Jing-Jing Li,Feng Xie,Yan Wei,Meng Yang
Metal oxides nanomaterials are limited in electrochemical detection of heavy metal ions (HMIs) because of their poor conductivity and less active sites, which hinders electron transport and reduce the redox rate of HMIs, making it difficult to achieve sensitive and accurate detection of trace pollutions. Herein, Ru-loaded cerium dioxide nanocubes (Ru/CeO 2 ) with rich oxygen vacancies (OVs) was developed to construct electrochemical sensing interface. An unexpected sensitivity of up to 2169.8 μA μM −1 cm -2 was obtained with a detection limit of 0.019 μM in the detection of Hg(II). The predominantly exposed highly active (100) crystal facets and abundant OVs on the surface of CeO 2 nanocubes, as well as Ru nanoparticles with excellent metal activity, providing large amounts of reactive oxygen species and active sites, thereby enhancing the conductivity and adsorption capacity of the nanocomposites. Ultimately, the outstanding electrochemical signal was achieved by promoting the redox reaction of Hg(II). In addition, the proposed method shows the excellent stability and high anti-interference ability, and the accurate analysis of Hg(II) in real water samples was realized. This finding provides a good strategy for the development of nano-metal oxide with OVs for the reliable determination of trace heavy metal substance.
研究领域:
材料科学
·
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2021
·
IF 7.46
Lei Liu,Yue Yao,Kejian Ma,Changjian Shangguan,Songlong Jiao,Songyang Zhu,Xiaoxuan Xu
Elucidation of the photoelectrochemical (PEC) detection mechanism and exploring highly efficient photoactive materials hold both a challenge and an opportunity to construct high-performance biosensors. In this work, we present a strategy to enhance the charge separation efficiency by fabricating hierarchical Ti 3 C 2 @ReS 2 via the vertical anchoring flaky ReS 2 on the Ti 3 C 2 backbone. According to the experimental results, the Ti 3 C 2 @ReS 2 sample containing 45 wt % of ReS 2 exhibits a 2.48-time promotion in the photocurrent as compared to ReS 2 owing to the synergistic effects of its photoactive and conductive counterparts, indicating its significant advantages in separating photo-induced carriers and suppressing carrier recombination. In essence, the Ti 3 C 2 @ReS 2 Schottky junction formed at the interface can capture the photogenerated electrons generated by ReS 2 , thereby suppressing carrier recombination. As a result, an ultrasensitive PEC detection platform based on the optimized Ti 3 C 2 @ReS 2 can offer a log-linear detection window from 0.1 fM to 1 nM with an estimated detection limit of 2.4 aM (S/N = 3) for cancer-related miRNA-141 without any other amplification.
研究领域:
材料科学
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生物传感器
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癌症研究
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光电化学
✓ 已验证
DOI
高影响因子
MICROCHEMICAL JOURNAL
·
2025
·
IF 5.1
Hui Dong,Linlin Zheng,Zhenlong Jiang,Tao Wang,Xinyue Li,Yangyang Ma,Zhu Chang,Xuechuan Lv,Xiaohan Gao,Maotian Xu,Yanli Zhou
Maltol (MA) is a common additive used in many fields, and its detection is of great importance to human health. Here, we synthesized a bimetallic MOF (CuNiMOF) based on graphite paper by a fast, simple, and green electrodeposition method. Then, we constructed a self-calibrated MOF to detect maltol. CuNiMOF was based on graphite paper by a fast, simple, and green electrodeposition method, and then constructed a self-calibrated flexible biosensor for the detection of maltol. In this work, we utilized the amperometric i-t curve (IT), cyclic voltammetry (CV), and multipotential step (STEP) methods to electrosynthesize three modified electrodes (Gp/CuNiMOF/IT, Gp/CuNiMOF/CV, Gp/CuNiMOF/STEP). The MA was characterized by differential pulse voltammetry electrochemical reactions on the electrode surface were investigated. The results showed that compared with the other two electrodeposition processes, the IT method was used to the sensor prepared by the IT method exhibits superior performance compared to the other two electrodeposition processes. The nonlinear response of the sensor to MA was in the concentration range of 0.5 ∼ 450 μM with a detection limit of 0.17 μM.
研究领域:
分析化学
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材料科学
·
电化学传感器
✓ 已验证
产品关联
DOI
高影响因子
SENSORS AND ACTUATORS B-CHEMICAL
·
2019
·
IF 6.393
Li Fu,Aiwu Wang,Kefeng Xie,Jiangwei Zhu,Fei Chen,Henggang Wang,Huaiwei Zhang,Weitao Su,Zhenguang Wang,Cangtao Zhou,Shuangchen Ruan
Sensitive and low-cost determination of Ag + is important due to the potential risk of Ag + increasingly applied in various fields. In this work, we report an extremely simple electrochemical sensor for the Ag + determination based on the sulfur quantum dots (SQDs) modified Au electrode. The SQDs were synthesized by a top-down method through alkali etching of bulk sulfur powder, which were then directly used for Au electrode surface modification due to the high affinity between Au and S atoms. The strong binding between Ag and S makes the modified electrode highly sensitive for Ag + sensing. The theoretical investigation was carried out by calculating the bond length and binding strength between Ag and S. Since the non-conductive nature of the SQDs, the amount of modifier is a crucial factor for the sensing performance. Under optimum condition, the proposed sensor showed a linear detection range of 0.1 nM to 3 μM with a detection limit of 71 pM.
研究领域:
分析化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
ELECTROANALYSIS
·
2019
·Vol. 32
·期 3
·620-625
·
IF 2.691
Xiangyu Ma,Kun Qian,Martha Kandawa-Schulz,Weimin Miao,Yihong Wang
Copper ion (Cu 2+ ) is one of the heavy metal ions which has been considered as a severe pollutant affecting the environment and human health. Therefore, it is necessary to detect Cu 2+ sensitively and conveniently in food and drinks. However, the gold standard method that inductively coupled plasma mass spectrometry (ICP-MS) is expensive equipment required and time-consuming. In this work, a highly sensitive and facile electrochemical method was studied to directly determine the concentration of Cu 2+ without cumbersome modification on the surface of glassy carbon electrode (GCE). In the presence of ferric ion (Fe 3+ ), Cu 2+ could play a role of catalyst in the detection system, and the electrochemical signal of differential pulse voltammetry (DPV) response to Cu 2+ could be amplified obviously. Under the optimal conditions, a good linear relationship was obtained in the range of 1 nM to 5 μM with a detection limit of 57.5 pM (S/N=3) were obtained. Besides, the proposed method has good applicability for the detection of Cu 2+ in tap water. Furthermore, the copper complex was detected and the results were indicated the proposed method was effective and sensitive.
研究领域:
环境科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
e-Journal of Surface Science and Nanotechnology
·
2023
·Vol. 21
·期 1
·1-8
·
IF 0.7
J. F. Huang,F. H. Tao,F. Y. Li,Z. Y. Cai,L. Z. Pei
Polypyrrole (PPy)/CuBi2O4 nanosheets (NSs) were prepared by an in situ polymerization process and the NS-modified glassy carbon electrode (GCE) for electrochemical determination of benzoic acid was studied. The structure, morphology, and functional groups of the PPy/CuBi2O4-NSs were analyzed by X-ray diffraction, transmission electron microscopy (TEM), high-resolution TEM, and Fourier transform infrared spectroscopy. The obtained NSs contain a tetragonal CuBi2O4 phase, and nanoscale PPy particles attach to the surface of the NSs. The electrochemical responses of the PPy/CuBi2O4-NS-modified GCE in 0.1 M KCl solution with benzoic acid were investigated by the cyclic voltammetry (CV) and electrochemical impedance spectroscopy. An irreversible CV peak is located at −0.84 V on the PPy/CuBi2O4-NS-modified GCE in 2 mM benzoic acid and 0.1 M KCl solution. The intensities of the CV peaks show linear variation with increasing the scan rate and concentration of benzoic acid. The linear range is 0.001−2 mM with a detection limit of 0.52 μM. The PPy/CuBi2O4-NS-modified GCE shows high stability and reproducibility. The prepared PPy/CuBi2O4-NSs have great promise in the electrochemical detection of benzoic acid.
研究领域:
材料科学
·
分析化学
✓ 已验证
产品关联
DOI
高影响因子
JOURNAL OF SOLID STATE ELECTROCHEMISTRY
·
2016
·Vol. 21
·期 3
·793-801
·
IF 2.327
Dong Sheying,Li Miao,Wei Wenbo,Liu Dan,Huang Tinglin
A substantial outstanding challenge in diagnostics and disease monitoring is the ability to assay rapidly and conveniently for protein biomarkers within complex biological media. Bi 2 Se 3 , as an important topological insulator (TI) material, was synthesized by a solvothermal method and characterized structurally. Subsequently, the composite of Bi 2 Se 3 and ionic liquid ([BMIm]BF 4 IL) was used as a sensing interface to cross-link goat anti-human immunoglobulin G (anti-IgG) via glutaraldehyde (GA) to fabricate an Bi 2 Se 3 /IL/GA/anti-IgG-carbon paste electrode (CPE). The nonspecific binding sites were enclosed with bovine serum albumin (BSA) to develop a label-free IgG immunosensor. The result showed that the proposed label-free IgG immunosensor exhibited high specificity with a detection limit of 0.8 ng mL −1 and linear range from 2 to 300, and 300 to 2200 ng mL −1 . Besides, the immunosensor exhibited high specificity for IgG detection, acceptable reproducibility, and stability. Thus, the strategy reported here paved a simple way to design a sensitive and cost-effective sensing platform for extension to other disease biomarkers.
研究领域:
生物医学工程
·
材料科学
·
诊断学
✓ 已验证
产品关联
DOI
高影响因子
危险品化学品经营许可证（带存储）