Polymer Chemistry
·
2020
·Vol. 11
·期 41
·6650-6657
·
IF 5.342
Shanshan Chen,Tingting Sun,Zhigang Xie,Dewen Dong,Ning Zhang
Mobile divalent zinc, Zn(II), is an essential cofactor involved in mammalian biological processes. To understand the intrinsic action mechanism of mobile zinc, the development of a Zn2+-selective fluorescent probe that can detect mobile zinc via biological imaging is of great significance. We present here a novel Zn2+-selective fluorescent sensor based on poly(2-oxazoline) (POx) cylindrical molecular brushes with good water solubility and biocompatibility. The POx molecular brushes were end-capped by a Zn2+-responsive functionality, which can give efficient blue emission upon coordination with zinc ions. Fluorescence investigation indicates that the POx molecular brushes exhibit superior selectivity toward Zn2+ in comparison with most competitive heavy and transition metal ions. Due to the ease of cellular uptake that results from their unique molecular contour, POx molecular brushes are capable of detecting intracellular Zn2+ ions as demonstrated by living cell fluorescence studies.
研究领域:
生物化学
·
材料科学
·
分析化学
✓ 已验证
DOI
高影响因子
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
·
2020
·
IF 2.69
Ye Han Yan,Muhammad Atif,Ren Yong Liu,Hai Kun Zhu,Li Juan Chen
In this work, the comb-like poly(2-methyl-2-oxazoline) copolymer, poly(2-aminoethyl methacrylate-random-poly(2-methyl-2-oxazoline) (PMOXA-r-AEMA, PMA) is synthesized, and the CuSO4/H2O2-triggered dopamine/PMA co-deposition process is investigated. Ellipsometry, water contact angle (WCA), and X-ray photoelectron spectroscopy (XPS) are used to characterize the thickness, hydrophilicity, and surface composition of PMA-based coatings. PMA is facilely anchored to substrates within 60 min with the assistance of dopamine/polydopamine triggered by CuSO4/H2O2, and the coating thickness can achieve about 13 nm. Anti-protein adsorption and anti-blood platelet adhesion measurements are also studied to verify their antifouling properties. The adsorption capacity of FITC-BSA can be reduced to 5% of the original surface, and PMA-based coatings present excellent protein-resistant properties (∼95% reduction relative to gold surface) according to surface plasmon resonance (SPR) measurement, and it can resist adhesion of almost all blood platelets. Moreover, it is applied to a capillary inner wall for surface modification. An alkaline protein mixture and egg white proteins are successfully separated, and present excellent stability. The relative standard deviation (RSD) of migration time is lower than 0.71%. The practicability of this promising PMA-based coatings with this preparation strategy can be used for further proteomics analysis.
研究领域:
材料科学
·
生物医学工程
·
表面化学
✓ 已验证
产品关联
DOI
PubMed
高影响因子
Journal of Materials Chemistry B
·
2014
·Vol. 2
·期 44
·7785-7794
·
IF 0
Longchao Bai,Lin Tan,Lijuan Chen,Songtao Liu,Yanmei Wang
Poly(2-methyl-2-oxazoline) (PMOXA) has been proved to be a kind of potential antifouling coating material. In this work, a series of comb copolymers, poly[(2-methyl-2-oxazoline)-random-glycidyl methacrylate] (PMOXA-r-GMA), with a variety of compositions were synthesized by free radical polymerization of the oligo(2-methyl-2-oxazoline) methacrylate macromonomer and glycidyl methacrylate, and then characterized and used to coat silicon/glass surfaces. A one-step coating procedure by a simple annealing protocol was used to yield covalent and cross-linked PMOXA-based antifouling coatings. The coatings were rigorously characterized in terms of the surface chemical composition, hydrophilicity, thickness and morphology using X-ray photoelectron spectroscopy (XPS), the water contact angle (WCA) test, ellipsometry and atomic force microscopy. The results demonstrated that the PMOXA-r-GMA brushes could successfully be bonded onto silicon/glass surfaces. Finally, the fouling resistance ability of the modified surface was evaluated by analyzing the adsorption of bovine serum albumin protein, bacterial cell attachment and platelet adhesion, which indicated that the modified silicon/glass surfaces had a superior resistance to protein, bacterial cell and platelet adsorption, and the performance of fouling resistance was enhanced with the content of PMOXA segments in the copolymers.
研究领域:
材料科学
·
生物医学工程
·
表面化学
✓ 已验证
DOI
PubMed
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
·
2013
·Vol. 160
·期 8
·H502
·
IF 2.588
Wu Lei,Zhenyan Gu,Weimeng Si,Fengxiang Wang,Qingli Hao
Conducting poly (2,6-dimethoxynaphthalene) (PDMN), a novel fluorescent polymer was electrochemically synthesized in boron trifluoride diethyl etherate (BFEE) containing additional concentrated sulfuric acid via direct anodic oxidation of 2,6-dimethoxynaphthalene (DMN). The oxidation potential onset of DMN in this medium was 0.43 V, lower than other electrolyte media. PDMN films showed good electrochemical behavior and thermal stability. The structure and morphology of the polymer were investigated in detail. Fluorescent spectra indicated that the electrochemically polymerized PDMN was an excellent blue light-emitting material. The insoluble PDMN film deposited on the indium tin oxide glass was used to develop a sensor for the determination of imidacloprid based on the fluorescence quenching of PDMN. The interaction of imidacloprid and PDMN was investigated by electrochemical techniques. The fluorescent intensity of PDMN has a good linear relationship with the concentration of imidacloprid on the surface of PDMN in the range of 4.994 × 10−1 to 2.557 × 102 μg/mL with a detection limit of 3.093 ng/mL. The sensor based on PDMN films showed high recognition ability for imidacloprid and will have more potential applications in the industrial or environmental and healthy fields.
研究领域:
材料科学
·
环境科学
·
分析化学
✓ 已验证
DOI
高影响因子
Journal of Materials Chemistry A
·
2023
·Vol. 11
·期 18
·9955-9963
·
IF 11.9
Xin Ren,Donggang Tao,Yudi Tang,Yuliang Cao,Fei Xu
Rechargeable Mg batteries (RMBs) are promising devices for large-scale energy-storage applications, but the lack of cathode materials is hindering their development. Conjugated organic polymers provide more selection by breaking the limit of the inorganic crystal lattice. Herein, a series of poly(2,6-anthraquinonyl polysulfide)s with different sulfur chains (AQ units are connected with polysulfides, 26PAQSx, x = 1, 1.4, 1.9 and 2.2) are synthesized and investigated as RMB cathodes. 26PAQS1.9 provides a high capacity of 270 mA h g−1 at 50 mA g−1 exceeding that of the two-electron carbonyl enolization, with the extra capacity being delivered by formation of the SO/S–O bond between the enolized carbonyl (C–O−) and the S–S unit. The sulfur chain of 26PAQSx is stable when 1.0 < x < 2.0, and 26PAQS1.9 exhibits a stable cycling for 500 cycles at 2C. The formation of the SO/S–O bond is highly reversible and fast, and 26PAQS1.9 shows a good rate capability of 86 mA h g−1 at 5.0 A g−1 (about 20C). The new mechanism revealed herein would inspire new insight for the design of conjugated carbonyl polymers as RMB cathodes.
研究领域:
材料科学
·
电化学
·
能源存储
✓ 已验证
DOI
高影响因子
PHYTOCHEMICAL ANALYSIS
·
2022
·Vol. 33
·期 4
·590-598
·
IF 3.024
Xuemei Xue,Fei Deng,Zhenkai Ge,Jingwen Meng,Xiya Liu,Yongheng Zhao,Yanggen Hu,Xu Ling
Introduction The quantitative analysis of trace resveratrol and polydatin in plant tissues is suitable for elucidation of the compounds' mechanisms of action. Objectives The main objective of this work was to develop a feasible and effective sample pretreatment method to measure the concentrations of resveratrol and polydatin in complex samples. Methodology A polymer sorbent, poly(2-mercaptobenzimidazole), was electrochemically prepared and utilized for selective extraction, while resveratrol and polydatin were used as target analytes. The sorbent was characterized by cyclic voltammetry, scanning electron microscopy and Fourier transform infrared spectroscopy. After extraction and elution, the analytes were analyzed by a Thermo U3000 HPLC system. Several affecting parameters, including the volume of elution solution, sample pH value, sample flow rate and sample volume, were evaluated and optimized. Results The proposed method showed good linearity with low limits of detection (from 0.5 to 0.8 ng·mL −1 ) and ideal accuracy with spiked recoveries from 81.30% to 99.16%. A good enrichment factor (more than 200-fold) together with good sensitivity was obtained with this method. Analysis of resveratrol and polydatin in Polygonum cuspidatum samples by this method is efficient. Conclusion The method developed in this work exhibits several significant merits, including easy operation and high extraction efficiency, indicating that electrochemically prepared polymer sorbent is useful for sample pretreatment and analysis of traditional Chinese medicine samples.
研究领域:
分析化学
·
中药学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2013
·Vol. 4
·期 1
·510-515
·
IF 2.562
Huan Wang,Baoqing Shentu,Zhixue Weng
A one-pot synthetic approach for the preparation of poly(2,6-dimethyl-1,4-phenylene oxide)/polystyrene (PPO/PS) alloy in aqueous medium was developed. The method was based on the combination of the oxidative coupling polymerization of 2,6-dimethylphenol (DMP) to form PPO in the presence of a reactive swelling agent, styrene (St), and in situ reverse atom transfer radical polymerization (RATRP) of St initiated by 2,2′-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride (AIBI) in alkaline aqueous solution. The complex of CuCl2 and 4-dimethylaminopyridine (DMAP) was utilized as the catalyst to catalyze the two types of polymerization mentioned above. Oxygen was employed as the sole oxidant to synthesize PPO. The introduction of St during the oxidative polymerization of DMP could increase the molecular weight of PPO. Finally thermodynamically compatible PPO/PS alloy was successfully prepared.
研究领域:
高分子化学
·
材料科学
✓ 已验证
DOI
高影响因子
POLYMER
·
2024
·
IF 4.1
Hongjing Pei,Yanmei Han,Yong Liu,Xu Han
Although copper-aliphatic amines have been extensively used as catalysts for the polymerization of 2,6-dimethylphenol (DMP) to poly (2,6-dimethyl-1,4-phenylene oxide) (PPO), the high polydispersity index (PDI) of PPO and high content of 3,3′,5,5′-tetramethyl-4,4'diphenoquinone (DPQ) in PPO significantly affect the physical properties of PPO . In this study, different CuBr-aromatic amines have been used as catalysts for synthesizing PPO. CuBr– N -methylbenzylamine shows a high yield of PPO (94.4 %) with the low DPQ yield (0.46 %) and PDI (1.33) in the presence of 0.1 % H 2 O, which facilitates the formation of dinuclear Cu(Ⅱ) species. In addition, the low dielectric constants (2.43 and 2.25) and low dielectric loss factors (1.07 × 10 −3 and 1.29 × 10 −3 ) of the PPO synthesized by CuBr– N -methylbenzylamine and CuBr-4-aminopyridine again indicate that aromatic amines are more appropriate for the synthesis of PPO with superior dielectric properties . Meanwhile, the high-molecular-weight PPO can be successfully redistributed to low-molecular-weight PPO by adding DMP in the presence of CuBr– N -methylbenzylamine, and the decreased T g values from 212.5 to 187.8 °C with decreasing M n values from 2.7 × 10 4 to 5.5 × 10 3 indicate the improved processability of the low-molecular-weight PPO. This study provides new insights on important roles of aromatic amines in the synthesis of PPO.
研究领域:
高分子化学
·
材料科学
✓ 已验证
产品关联
DOI
高影响因子
Journal of Materials Chemistry A
·
2014
·Vol. 2
·期 43
·18562-18573
·
IF 0
Lijia Yang,Beibei Tang,Peiyi Wu
In this work, graphene oxide (GO) was first functionalized with branched polyethyleneimine (PEI). The obtained PEI–GO was incorporated into a brominated poly(2,6-dimethyl-1,4-phenylene oxide) (BPPO) matrix by a covalent bond interaction to form a cross-linking network. Then, a novel ultrafiltration (UF) membrane was prepared via casting and phase-inversion methods. The PEI–GO/BPPO membrane showed highly improved water flux, which was almost 6 times higher than that of the pristine BPPO membrane and 2.5 times higher than that of the GO/BPPO membrane, whereas the rejection of PEI–GO/BPPO membrane was still maintained at a high level. The improvement of membrane performance could be attributed to the special property of PEI–GO and the interactions between PEI–GO and the BPPO matrix. First, a cross-linking network of PEI–GO/BPPO membrane was formed because of the reaction between PEI–GO and the BPPO matrix to provide passageways for water rapidly passing through. Second, the high hydrophilicity of PEI–GO could accelerate the exchange rate between solvent and non-solvent, resulting in a rougher and more hydrophilic surface, higher porosity and a more porous structure. Third, the good dispersion and compatibility of PEI–GO promoted the formation of a uniform structure with fewer defects. Proper molecular weight of PEI was very important for the modification of GO, subsequently resulting in an overall enhancement in membrane performance. Anti-fouling experiments and stability tests of the membranes were also conducted. All of these results were confirmed by various characterizations, such as SEM, TEM, AFM and, etc.
研究领域:
材料科学
·
环境工程
✓ 已验证
DOI
Polymers
·
2022
·Vol. 14
·期 13
·2748
·
IF 4.967
He Xi,Zhicheng Song,Yonggang Guo,Weijia Zhu,Lisong Ding,Weidong Zhu,Dazheng Chen,Chunfu Zhang
To promote the performance of perovskite solar cells (PSCs), its theoretical power conversion efficiency (PCE) and high stability, elaborative defect passivation, and interfacial engineering at the molecular level are required to regulate the optoelectric properties and charge transporting process at the perovskite/hole transport layer (HTL) interfaces. Herein, we introduce for the first time a multifunctional dipole polymer poly(2-ethyl-2-oxazoline) (PEOz) between the perovskite and Spiro-OMeTAD HTL in planar n-i-p PSCs, which advances the PSCs toward both high efficiency and excellent stability by stimulating three beneficial effects. First, the ether–oxygen unshared electron pairs in PEOz chemically react with unsaturated Pb2+on the perovskite surfaces by forming a strong Pb–O bond, which effectively reduces the uncoordinated defects on the perovskite surfaces and enhances the absorption ability of the resulting PSCs. Second, the dipole induced by PEOz at the perovskite/HTL interface can decrease the HOMO and LUMO level of Spiro-OMeTAD and optimize the band alignment between these layers, thereby suppressing the interfacial recombination and accelerating the hole transport/extraction ability in the cell. Third, the hygroscopic PEOz thin film can protect perovskite film from water erosion by absorbing the water molecules before perovskite does. Finally, the PEOz-modified PSC exhibits an optimized PCE of 21.86%, with a high short-circuit current density (Jsc) of 24.88 mA/cm2, a fill factor (FF) of 0.79, and an open-circuit voltage (Voc) of 1.11 V. The unencapsulated devices also deliver excellent operation stability over 300 h in an ambient atmosphere with a humidity of 30~40% and more than 10 h under thermal stress.
研究领域:
材料科学
·
光伏技术
·
界面工程
✓ 已验证
DOI
高影响因子
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
·
2019
·
IF 3.131
Feng Su,Peng Yun,Chenglong Li,Rongye Li,Laishun Xi,Yuandou Wang,Yangsheng Chen,Suming Li
A series of poly(2-ethyl-2-oxazoline)-poly(L-lactide) (PEOz-PLA) diblock copolymers were synthesized by ring-opening polymerization of l -lactide using a monohydroxy terminated PEOz-OH macro-initiator in the presence of stannous octoate as catalyst. The resulting diblock copolymers were characterized by 1 H nuclear magnetic resonance and gel permeation chromatography . Self-assembled micelles were prepared using the co-solvent evaporation method in water and in phosphate buffered saline (PBS) at pH 7.4, 6.5 and 5.0. The resulting micelles exhibit different morphologies, such as spherical micelles and worm-like micelles depending on the hydrophilic/hydrophobic balance. Spherical micelles were exclusively observed for PEOz-PLA copolymers with short PLA blocks, whereas co-existence of worm-like and spherical micelles was observed for copolymers with long PLA blocks. The micelle size increases with decreasing pH due to the electrostatic repulsion between PEOz chains resulting from ionization of the tertiary amide groups along PEOz chains. A hydrophobic anti-tumor drug, paclitaxel , was entrapped in PEOz-PLA micelles. High loading efficiency up to 86.7% was obtained for copolymers with long PLA blocks. Drug release was performed in PBS at different pH values. During the 30-day release period, faster release was obtained for copolymers with shorter PLA blocks than for copolymers with longer PLA blocks, at acidic pH than at pH 7.4. It is thus concluded that pH-responsive PEOz-PLA copolymer micellss could be promising as carrier of anti-tumor drugs.
研究领域:
生物材料学
·
药剂学
·
高分子化学
✓ 已验证
DOI
高影响因子
CHEMICAL ENGINEERING JOURNAL
·
2022
·
IF 16.744
Hailong Yang,Hantian Lu,Yueyue Miao,Yang Cong,Yubin Ke,Jun Wang,Hua Yang,Jun Fu
Non-swelling super-tough polymer hydrogels have great potentials for stable applications in wet conditions. It has been challenging since most polymer hydrogels uptake water from the environment and swell, which deteriorates the mechanical strength and toughness. Here, we present multi-responsive non-swelling polymer hydrogels ( PHFGs ) by using amphiphilic triblock copolymer micelles as non-covalent crosslinkers. Pluronic F127 (or polyethylene oxide- block -polypropylene oxide- block -polyethylene oxide, PEO-PPO-PEO) (F-127) micelles are used as a prototype for the synthesis of micelle-crosslinked poly-(2-hydroxyethylene methacrylate) (PHEMA) hydrogels, without using any modification of F-127 or other crosslinkers. FT-IR and 1 H NMR studies provide first evidence that F-127 micelles form extensive hydrogen bonding and hydrophobic association with PHEMA chains. The non-covalent crosslinked hydrogels show a high fracture elongation about 460 %, a fracture strength about 240 kPa, and a fracture toughness about 660 kJ/m 3 . Negligible swelling is observed for the polymer hydrogels in aqueous solutions. The hydrogels are self-healable, and responsive to variations in pH or water content to change volume, shape, and transparency. Such multiple-responsive polymer hydrogels are utilized as smart switches and shape memory materials that are actuated by environmental stimuli in a controllable manner.
研究领域:
材料科学
·
高分子化学
·
智能材料
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）