Food Chemistry-X
·
2026
·
IF 8.2
Guangjia Lv,Dehai Li,Chengsen Hou,Mingsen Wang,Xuan Zhang,Wendi Zhang,Yihong Bao,Yutong Zhang,Yanjun Zhang
This research explores the mechanisms underlying the interactions within the cassava starch (CS)-hemicellulose (HE)-sinapic acid (EA) ternary complex. The results demonstrate that CS, HE, and EA predominantly form a ternary complex through hydrogen bonding and hydrophobic interactions. Specifically, HE intertwines with CS, while EA tends to attach and interact with HE. In the ternary system, EA interferes with the formation of double-helix-like structures between CS and HE, whereas HE impedes the formation of V-type complexes between CS and EA. These interactions influence the macroscopic properties of the ternary complex. HE and EA act synergistically to decrease viscosity and reduce digestibility, whereas antagonistic effects are observed in enhancing crystallinity and improving thermal stability. Overall, these findings elucidate the molecular-level interaction mechanisms among CS, HE, and EA within the ternary system and provide new insights into starch modification and the development of low-glycemic-index foods from a multicomponent perspective.
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JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY
·
2025
·
IF 2.4
Zichen Shang,Jingzhou Liu,Sifan Jiang,Keyi Bao,Zeni Zheng,Sheng Han,Jincan Yan
The main challenge to the use of vegetable oils as green lubricants is their oxidative stability. In this work, biolubricants with efficient antioxidant properties have been specifically designed and synthesized with the aim of maximizing the oxidative stability of vegetable oils by combining biophenols (p-coumaric, ferulic, and sinapic acids) with epoxidized ring-opened soybean oil in a single molecule. The synthetic products were named OIS-ESO-PCA (epoxidized ring-opened soybean oil grafted with p-coumaric acid), OIS-ESO-FA (epoxidized ring-opened soybean oil grafted with ferulic acid), and OIS-ESO-SA (epoxidized ring-opened soybean oil grafted with sinapic acid), respectively. Biophenols improve biolubricant antioxidant properties, addressing energy, and environmental challenges. The modified samples were characterized by Fourier transform infrared spectroscopy (FT-IR) and nuclear magnetic resonance (NMR). The free radical scavenging activity of the oil samples was evaluated using the DPPH (1,1-diphenyl-2-trinitrophenylhydrazine) method and was found to be much higher than that of the soybean oil (SBO). The oxidation resistance and thermo-oxidative stability of the oil samples were evaluated based on pressure differential scanning calorimetry (PDSC), rotary bomb oxidation test (RBOT), and thermogravimetry (TGA). Compared with SBO, the oxidative induction time of OIS-ESO-PCA, OIS-ESO-FA, and OIS-ESO-SA increased by 118%, 296%, and 384%. The modified oils showed excellent antioxidant properties compared to the SBO. Therefore, biophenolic acid can be effectively used to improve the antioxidant properties of vegetable oils. Graphical Antioxidant capacity of bio-phenolic oil samples.
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FOOD RESEARCH INTERNATIONAL
·
2025
·
IF 8
Lulu Wu,Fujing Zheng,Huiying Li,Mario Prejanò,Tiziana Marino,Nino Russo,Yongsheng Tao,Yunkui Li
The effect of hydroxycinnamic acids on the aroma formation of Cabernet Sauvignon dry red wine and the molecular mechanism were explored. Four hydroxycinnamic acids were added singly before alcoholic fermentation. Volatile components were analyzed qualitatively and quantitatively and aroma characteristics were evaluated by sensory analysis. The thermodynamic parameters of caffeic acid interacted to five esters were determined in simulated solution, and the effect of caffeic acid on the volatility of the esters was explored with GC-FID. Dispersion-corrected density functional theory (DFT) was applied for the molecular mechanism investigation between caffeic acid and esters. The results showed that the addition of hydroxycinnamic acid to wine caused an increase of esters, particularly in acetate, with ranging from 3.01 to 43.03 mg/L. Sensory evaluation revealed maximum intensity increases of 79.4 % (floral aroma), 26.3 % (fruity aroma), and 21.1 % (sweet aroma) in the treatment group. The interaction between caffeic acid and esters is a spontaneous exothermic reaction that inhibited the volatilization of esters. The retention effect is affected by the concentration of caffeic acid and the skeletal structure of esters. Theoretical studies have shown that the interaction between caffeic acid and esters is mainly driven by a combination of hydrophobic interactions, hydrogen bonding and dispersion, with the main driving force varying depending on the ester backbone. The hydroxyl group of caffeic acid and the ester group on the esters are the key sites for molecular interactions.
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MOLECULES
·
2026
·Vol. 31
·期 4
·621
·
IF 5.1
Ying Zhao,Yubo Lu,Yushan Ma,Sijia Wang,Pin Lv,Huifang Xu,Yuanyuan Li,Weisheng Feng
Breast cancer ranks among the most prevalent malignant tumors globally, underscoring the urgent need for efficient and low-toxicity treatment strategies. In this study, a novel nanomedicine (BBR-SA) was constructed based on the self-assembled of berberine (BBR) and sinapic acid (SA) for synergistic chemotherapy. Firstly, utilizing π-π stacking, hydrogen bonding, and electrostatic forces between BBR and SA, the BBR-SA achieved a well-defined nanostructure with high drug-loading capacity and favorable water dispersibility. Furthermore, BBR-SA nanomedicine effectively inhibited the proliferation of mouse mammary carcinoma cells (4T1), showing a significantly stronger inhibitory effect than either BBR or SA alone. Moreover, the remarkable anti-tumor effect was obtained after treatment with BBR-SA nanomedicine in vivo, further demonstrating a synergistic therapeutic effect. More importantly, no significant systemic toxicity was observed after 28 days of intravenous administration with BBR-SA nanomedicine. In summary, the BBR-SA nanomedicine represents a safe and effective therapeutic strategy for breast cancer, offering new perspectives on the application of the traditional chinese medicine in anti-tumor therapy.
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JOURNAL OF FOOD COMPOSITION AND ANALYSIS
·
2026
·
IF 4.6
Zhihao Yang,Tianle Shen,Jinhu Tian,Yanbin Wang,Xingqian Ye,Jianchang Jin,Dan Wu
The determination of phenolic compounds serves as a critical approach for food quality control and screening of bioactive phytochemicals. This study developed a high-performance liquid chromatography-photodiode array detection (HPLC-PDA)-based analytical technique for plant phenolics, enabling simultaneous accurate quantification of 37 representative phenolic compounds in samples. Method validation demonstrated excellent linearity, precision, and accuracy, with intra-day and inter-day precision below 3 %, and spiked recoveries ranging from 96.88 % to 103.75 %. The methodology was successfully applied to analyze 19 distinct plant specimens, confirming its exceptional versatility. This method can be used as an efficient assay for plant polyphenols in multiple fields including food analysis, phytochemical research, and bioactive component development.
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LWT-FOOD SCIENCE AND TECHNOLOGY
·
2022
·
IF 6.056
Hao Zhang,Antonio Dario Troise,Shangde Sun,Vincenzo Fogliano
Plant food by-products are often characterized by a tight matrix of insoluble polysaccharides entrapping bioactive functional molecules. In this study, we investigated the impact of black currant pomace (BC), red cabbage waste (RC) and their water-insoluble fraction (IBC and IRC, respectively) on the formation of Maillard reaction and lipid oxidation products during thermal treatment of potato-based fried crisps. Results showed that the substitution of 20% potato flake with IBC and IRC significantly reduced the formation of acrylamide (14.7%–66.3%) and 5-hydroxymethylfurfural (15.9%–55.4%). This can be explained both by the inhibition of Maillard reaction by plant polyphenols and by the decrease of asparagine and reducing sugars concentration due to the partial replacement of potato flakes. On the opposite, the addition of BC and RC promoted acrylamide and 5-hydroxymethylfurfural formation, which is related to the high amount of reducing carbohydrate in BC and RC. Besides the higher recoveries of extractable polyphenols in IBC- and IRC-enriched crisps, all the four ingredients significantly inhibited the accumulation of 4-hydroxy-2-nonenal, 4-hydroxy-2-hexenal, malondialdehyde and acrolein. These findings highlighted that the elimination of water-soluble compounds is a potential strategy for using plants by-products as efficient ingredients in fried products to limit the formation of processing contaminants.
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Foods
·
2023
·Vol. 12
·期 4
·827
·
IF 5.2
Lili Cao,Pengpeng Jia,Haotian Liu,Shengmei Kang,Shaotong Jiang,Min Pang
Fragrant rapeseed oil (FRO) is a frying oil widely loved by consumers, but its quality deteriorates with increasing frying time. In this study, the effect of high-canolol phenolic extracts (HCP) on the physicochemical properties and flavor of FRO during frying was investigated. During frying, HCP significantly inhibited the increase in peroxide, acid, p-anisidine, and carbonyl values, as well as total polar compounds and degradation of unsaturated fatty acids. A total of 16 volatile flavor compounds that significantly contributed to the overall flavor of FRO were identified. HCP was effective in reducing the generation of off-flavors (hexanoic acid, nonanoic acid, etc.) and increased the level of pleasant deep-fried flavors (such as (E,E)-2,4-decadienal). Therefore, the application of HCP has a positive effect on protecting the quality and prolonging the usability of FRO.Keywords:canolol;fragrant rapeseed oil;frying process;flavor compounds
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INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY
·
2023
·Vol. 58
·期 5
·2247-2257
·
IF 3.3
Jiao Wu,Bingjun Han,Xiaoyu Chen,Jinglin Gao,Shan Zhao,Liping Sun,Shijie Wang
Summary Stingless bee honey is a precious food product with therapeutic benefits. In this study, we determined the quality of Malaysian stingless bee honeys ( Heterotrigona itama and Tetrigona binghami ) by the physicochemical characteristics, phenolic compounds, and organic acids. Our results revealed that the major phenolic compounds in all honey samples were chlorogenic acid and myricetin, and the major organic acids contained gluconic acid and trans -cinnamic acid. The microbial community in honeys characterised using 16S rRNA and ITS amplicon sequencing techniques showed that Lactobacillus was assumed to be the predominant bacterium in stingless bee honeys. Furthermore, the antibacterial activity of honeys was examined in order to further demonstrate their health benefits. Our results are intended to pave the road for stingless bee honeys' probiotic capacity to be extended into our daily life.
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BIOCATALYSIS AND BIOTRANSFORMATION
·
2022
·
IF 2.325
Jian Yao,Lun Gui,Qizhang Long
Soil microbes are an abundant source of enzymes with unique properties that may be useful for industrial applications. As most wild-type strains show low chlorogenic acid esterase expression and activity, and most microbes cannot be cultured in the laboratory, a metagenomic approach provides methods of identifying new enzymes. In this study, a gene encoding a chlorogenic acid esterase, named Tan410, was isolated from a soil metagenomic library and overexpressed in Escherichia coli BL21 (DE3). The recombinant enzyme, with a predicted molecular weight of 54.88 kDa, was purified to homogeneity. The Km and Vmax values for Tan410 were 1.26 mM and 0.33 mM min–1, respectively, with chlorogenic acid as the substrate. Its optimum temperature and pH for reaction were 30 °C and 7.5, respectively. The enzyme exhibited moderate thermostability and broad pH stability (3.0–10.0). Tan410 was also able to hydrolyse ethyl ferulate, methyl caffeate, propyl gallate, ethyl gallate, methyl vanillate, methyl benzoate, ethyl benzoate, methyl 2,5-dihydroxybenzoate, and methyl 3,5-dihydroxybenzoate, and it released caffeic and ferulic acids from agricultural byproducts (destarched wheat bran and coffee pulp). Tan140 has potential for industrial application in biomass valorization.
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SENSORS AND ACTUATORS B-CHEMICAL
·
2022
·
IF 9.221
Shuzhen Dou,Zhongshun Wang,Qiye Chen,Nan Lu
The high sensitivity of surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) analysis depends on the enhancement of the signal intensity and the reduction of the background. Here, high-density Si nanotips were prepared as SALDI-MS substrate by taking template-free reactive ion etching for sensitive detection . The high-density Si nanotips act as tiny antennas to concentrate the laser energy and generate photo-induced electrons on a small area, which promotes desorption and ionization of molecule, enhancing the signal intensity. Additionally, the high stability of Si nanotips under laser irradiation ensures low background interference. The applicability of the substrate was demonstrated by the detection of various small molecules, e.g., fatty acids, amino acids , environmental pollutants and drugs. In addition, this substrate can be successfully applied for detecting trace small molecules in complex sample, such as 10 −9 M verapamil in serum and 10 −12 M crystal violet in lake water. Moreover, the banned fungicides left on the fish skin was also detected. The substrate is compatible with imaging, and the endogenous and exogenous substances in fingerprint were visualized by MS imaging. These results demonstrate the easily prepared high-density Si nanotips SALDI-MS substrate is of high detection sensitivity and great value toward large-scale practical applications.
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TALANTA
·
2022
·
IF 6.556
Wenjing Gao,Bin Li,Ling Ling,Li Zhang,Shaoning Yu
Differentiating methicillin-sensitive and methicillin-resistant Staphylococcus aureus (MRSA and MSSA) is crucial for clinical diagnosis and anti-microbial treatment. Matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS) is an efficient tool for identifying pathogenic microorganisms at the bacterial species level. Here, we found that MRSA and MSSA can be differentiated by MALDI-TOF MS by employing (E)-propylα-cyano-4-hydroxyl cinnamylate (CHCA-C3) as the matrix, which shows great performance for proteins/peptides, especially hydrophobic proteins. The results show that the mass spectra profile of standard MRSA (ATCC 43300) is significantly different from the profiles of standard MSSA strains (ATCC 25923 and 29213) when using CHCA-C3 as the matrix compared to traditional matrix. The mass profiles had great reproducibility and were scarcely influenced by the growth medium. Due to the enhanced discrimination ability of CHCA-C3, we collected the mass spectra of 62 clinical S. aureus strains and selected four representative peaks for principal component analysis, which showed great differentiation. Our results suggest that employing a suitable matrix could enhance the discrimination ability of antibiotic-resistant bacteria by MALDI-TOF MS.
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JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
·
2022
·
IF 3.318
Jiawei Liu,Xiangwei Liu,Yingying Liu,Quan Bai
In this work, we prepared a novel graphene-based composite by combination of mercapto-end capped polyhedral oligomeric silsesquioxane (POSS-SH) with graphene oxide (GO) through covalent bonding process. The composite was further conjugated with 4-vinyl pyridine (4-VP) through thiol-ene click reaction to fabricate pseudo-mercaptoethyl pyridine functionalized POSS-graphene composite (G-POSS-S-VP). The physicochemical properties were confirmed via FT-IR, TGA, XPS, and TEM characterizations and a high ligand density of ca. 87.3 μmol m −2 was obtained. G-POSS-S-VP composite displayed high selectivity toward antibody, i.e., immunoglobulin G (IgG) in this case based on the hydrophobic charge induced chromatography (HCIC) mechanism. A high adsorption efficiency of ca. 90% and large adsorption capacity of 500 mg g −1 were achieved for IgG at pH 7.4. At the same time, the non-specific adsorptions of co-existing proteins on graphene substrate were obviously hindered. The practical applicability of G-POSS-S-VP composite as adsorbent was verified by selective separation of IgG from human serum. SDS-PAGE assay and MALDI-TOF-MS analysis clearly demonstrated the successful isolation of IgG with high purity.
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