Small
·
2010
·Vol. 7
·期 1
·87-94
·
IF 6.171
Yi-Lun Ying,Hai-Yan Wang,Todd C. Sutherland,Yi-Tao Long
An aptamer is a specific oligonucleotide sequence that spontaneously forms a secondary structure capable of selectively binding an analyte. An aptamer’s conformation is the key to specific binding of a target molecule, even in the case of very closely related targets. Nanopores are a sensitive tool for the single-molecule analysis of DNA, peptides, and proteins transporting through the pore. Herein, a single α -hemolysin natural nanopore is utilized to sense the conformational changes of an adenosine 5’-triphosphate (ATP)-binding aptamer (ABA). The known DNA sequence of the ABA is used as a model to develop real-time monitoring of molecular conformational changes that occur by binding targets. The native, folded ABA structure has a nanopore unfolding time of 4.17 ms, compared with 0.29 ms for the ABA:ATP complex. A complementary 14-mer strand, which binds the ABA sequence in the key nucleic acids responsible for folding, forms linear duplex DNA, resulting in a nanopore transit time of 0.50 ms and a higher capture probability than that of the folded ABA oligomer. Competition assays between the ABA:ATP and ABA:reporter complexes are carried out, and the results suggest that the ABA:ATP complex is formed preferentially. The nanopore allows for the detection of an ABA in its folded, ATP-bound, and linear conformations.
研究领域:
分子生物学
·
生物传感器
·
核酸化学
·
单分子检测
·
转化医学
✓ 已验证
DOI
高影响因子
MATERIALS LETTERS
·
2021
·
IF 3.423
Dan Liu,Sen Wen,Yuxiao Guo,Xingtian Yin,Wenxiu Que
Subject to the complexity and high cost of traditional semiconductor materials and manufacturing processes, the features of facile solution process with low cost have made the colloidal quantum dots (CQDs) more competitive, in which HgTe nanocrystals can be tuned as a potential in infrared region and achieve a great photoresponsivity. Herein, we reported the synthesis and characterization of HgTe CQDs materials by a facile solution process, and explored the relationship between the nanocrystal size and the reaction temperature and time, as well as the effect of the ligand exchange on the thickness of the HgTe CQDs film. The as-fabricated photoconductive device showed a high photoresponse even under a weak light, which provides a direction for the next-generation infrared photodetectors.
研究领域:
材料科学
·
纳米科技
·
光电子学
·
半导体物理
·
凝聚态物理
✓ 已验证
DOI
高影响因子
MACROMOLECULAR CHEMISTRY AND PHYSICS
·
2016
·Vol. 217
·期 24
·2726-2735
·
IF 2.495
Huiliang Sun,Shuren Zhang,Yike Yang,Xiao Li,Hongmei Zhan,Yanxiang Cheng
Six aryl Pd(II) bromide complexes based on perylene diimide derivative (Ar) and phosphine mixed-ligands are successfully synthesized by directly oxidative addition of Ar–Br to the Pd(0) precursor. These complexes with the general formulas ArPdBr(PCy 3 ) 2 (PCy 3 = tricyclohexylphosphine; Pd1–Pd3 ) and [ArPdBr(TXP-2,4)] 2 (TXP-2,4 = tri-2,4-xylylphosphine; Pd4–Pd6 ) are stable and can be handled in air at room temperature. By employing the Pd(II) complexes as initiators, Suzuki catalyst transfer polymerization (SCTP) of AB-type fluorene monomer is investigated for preparing polyfluorenes (PFs) with the defined end group. Complexes Pd4–Pd6 with auxiliary TXP-2,4 ligand can initiate polymerization of AB-type fluorene monomer at room temperature, while higher polymerization temperature is required for Pd1–Pd3 with alkyl phosphine PCy 3 . The obtained polymers are analyzed by matrix-assisted laser desorption ionization-time-of-flight mass spectrometry, which confirms that the Ar group is appended to the terminus of the polymer chain. Moreover, PFs prepared by Pd4–Pd6 -catalyzed SCTP bear precisely the Ar group on one chain end and 4- tert -butylphenyl end-capping group on the opposite end, which indicates that Pd4–Pd6 with the bulky TXP-2,4 exhibit better catalytic performance in SCTP. Photoluminescence spectra of the obtained polymers show a dual or a blue emission resulting from the difference of the molecular weight.
研究领域:
高分子化学
·
有机合成
·
功能材料
·
聚合反应机理
·
光电子材料
✓ 已验证
DOI
高影响因子
JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY
·
2013
·Vol. 51
·期 8
·1690-1694
·
IF 3.543
Yun-Hai Yu,Xiao-Hui Liu,Di Jia,Bo-Wen Cheng,Yuan-Lin Ren,Fei-Jun Zhang,Hui-Na Li,Peng Chen,Shan Xie
Graphical A universal high reactive ligand, Me 6 TREN, was successfully explored as the reducing agent for the ambient temperature copper-mediated LRP of AN. The key to success is ascribed to the optimized Me 6 TREN amount and reaction conditions employed, producing ideal living free radical polymerization characteristics. The very high chain-end functionality of the resultant polymer has been confirmed by GPC and 1 H NMR analyses as well as the chain-extension reaction.
研究领域:
高分子化学
·
聚合反应
·
功能高分子
·
可控自由基聚合
·
材料化学
✓ 已验证
DOI
高影响因子
Advanced Optical Materials
·
2022
·Vol. 10
·期 13
·2200276
·
IF 10.05
Chenwei Liu,Yongjie Liu,Shuxin Wang,Jiwei Liang,Cheng Wang,Fang Yao,Weijun Ke,Qianqian Lin,Ti Wang,Chen Tao,Guojia Fang
Quasi-two-dimensional (quasi-2D) perovskite light-emitting diodes (PeLEDs) are considered as one of the most potential candidates in electroluminescence territory owing to their unique quantum confinement effect and excellent thermal stability of the light. Nevertheless, heterogeneous energy domain distribution leads to severe non-radiative recombination in the process of energy transfer, which enormously hinders the performance and application of PeLEDs. Herein, an ambipolar amino acid, 5-aminovaleric acid (5AVA), is demonstrated to be able to coordinate lead and halides simultaneously with its carboxyl and amidogen groups. The coordinated ambipolar molecule not only reconstitutes energy domains of perovskites but also minimizes the interfacial defects of PeLEDs. Accordingly, the presence of 5AVA in perovskite precursors leads to dramatic suppression of the n = 1 and n = 2 phases and accelerates energy transfer from wide bandgap domains to narrow bandgap ones. As a result, maximum external quantum efficiency (EQE) of 19.3% (18.20% ± 1.10%) is achieved in quasi-2D green PeLEDs with current efficiency of 61.7 cd A −1 .
研究领域:
材料科学
·
光电子学
·
纳米科技
·
半导体器件
·
凝聚态物理
✓ 已验证
DOI
高影响因子
DALTON TRANSACTIONS
·
2018
·Vol. 47
·期 26
·8697-8705
·
IF 4.099
Yang Ding,Jie Liu,Ming Zeng,Xishu Wang,Junli Shi,Weili Wang,Yanru Miao,Xibin Yu
Rare earth (RE3+)-doped NaY(MoO4)2 nanocrystals are efficient materials for realizing multicolor emission, which plays an important role in displays, W-LEDs, solar cells and biolabeling. Up to now, research on the multicolor tuning properties of RE3+-doped NaY(MoO4)2 nanoparticles has mostly focused on traditional preparation routes such as the hydrothermal method and sol–gel process. However, the products obtained using these methods are usually large in size (on the micron/submicron scale) and agglomeration problems are inevitable. With the development of nano optoelectronic devices and bioluminescence labeling, there is an urgent need to find an efficient method to prepare nanoscale, monodispersed and NaY(MoO4)2:RE3+ nanocrystals (NCs) with good crystallinity and stronger emission properties. In this work, we demonstrate a simple, fast, reproducible and one-step synthesis of NaY(MoO4)2:Eu3+ NCs with sizes varying from 1–20 nm via a ligand-assisted reprecipitation strategy. The reaction mechanism and emission intensities of NaY(MoO4)2:Eu3+ NCs with various morphologies have been discussed in detail. Furthermore, Tb3+ and Eu3+ ion co-doped NaY(MoO4)2 NCs were also prepared, and various emission colors were obtained and tuned from red, orange-red, yellow and yellow-green to green. Energy transfer between the Tb3+ and Eu3+ ions in the NaY(MoO4)2 host matrix has also been demonstrated. Finally, a highly efficient and stable NaY(MoO4)2:0.05Tb,0.04Eu NC-based W-LED device was built, which indicates the promising future application for this material in the field of lighting. The tunable multicolour emission, ease of preparation and nanosize reveal that NaY(MoO4)2:RE3+ NCs have a potential application in full color displays and W-LEDs.
研究领域:
材料科学
·
纳米技术
·
光学材料
·
无机化学
·
光电子学
✓ 已验证
DOI
高影响因子
KINETICS AND CATALYSIS
·
2013
·Vol. 54
·期 6
·716-723
·
IF 0.543
Zeng Minfeng,Sun Xudong,Qi Chenze,Zhang Xian-Man
A novel and environmentally friendly heterogeneous catalyst has been prepared through the wet impregnation of copper(I) species onto the highly porous chitosan microspheres (CuI/PCMS). This novel CuI/PCMS heterogeneous catalyst with no additional ligands is much better than CuI homogeneous catalysts when applied in Heck reactions. Moreover, the reaction conditions are much milder than those for the similar copper catalysts mediated cross-coupling reactions reported in the literature. PCMS has been demonstrated not only the excellent solid support, but also have many unique functional groups to chelate the copper (I) species to enhance its catalytic activity.
研究领域:
催化化学
·
有机合成
·
材料化学
·
环境友好化学
·
功能高分子材料
✓ 已验证
DOI
高影响因子
JOURNAL OF THE CHINESE CHEMICAL SOCIETY
·
2017
·Vol. 64
·期 4
·412-419
·
IF 0.935
Xiu-Yan Dong,Sunday Folaranmi Akogun,Wei-Min Zhou,Wen-Kui Dong
A new tetranuclear Zn(II) complex, [{Zn(L)(μ-OAc)Zn(H 2 O)} 2 ], based on an asymmetrical salamo-type bisoxime chelating ligand H 3 L (6-hydroxy-4′-chloro-2,2′-[ethylenediyldioxybis(nitrilomethylidyne)]diphenol) was synthesized and characterized by elemental analyses, differential thermal methods, single-crystal X-ray crystallography, and IR, UV–vis, and fluorescence spectra. The Zn(II) complex crystallizes in the triclinic system, space group P -1 with cell parameters a = 9.0742(6) Å, b = 11.8225(5) Å, c = 12.4182(8) Å, Z = 2, V = 1212.56(12) Å 3 , R 1 = 0.0572, and wR 2 = 0.1734. The environment of the tetranuclear Zn(II) complex is penta-coordinated having a slightly distorted trigonal bipyramidal geometry. Moreover, a 1D chain supramolecular structure is formed along the c -axis by the intermolecular C1–H1B⋯O14 hydrogen bonds; in the same manner, C2–H2C⋯Cg2 functions in the formation of supramolecular structures along the a -axis of the 1D chain. A 2D supramolecular structure along the ac plane extends infinitely under the force of intermolecular hydrogen bonds. Differential scanning calorimetry-thermogravimetry thermal analysis provides evidence of the coordination of Zn(II) atoms to the ligand H 3 L. The Zn(II) complex shows intense photoluminescence with a maximum emission at ~453 nm upon excitation at 360 nm.
研究领域:
无机化学
·
配位化学
·
超分子化学
·
材料化学
·
分析化学
·
物理化学
·
晶体学
✓ 已验证
DOI
高影响因子
BIOCHEMICAL ENGINEERING JOURNAL
·
2021
·
IF 3.978
Jia-Li Gu,Wen-Yan Pi,Wei-Feng Xie,Jia-Wen Gu,Ya-Jun Wang,Li Xiao,Yong-Jin Li,Jing-Fen Li
The present work is aimed to improve the antibody adsorption performance of phenyl-based mixed-mode adsorbents by adjusting the functional group of ligand. Two new mixed-mode adsorbents coupled with 4-(aminomethyl)phenol (AMP) and 4-(aminomethyl)benzonic acid (AMA) were designed based on the structure of benzylamine (BA), where a hydroxyl or carboxyl group was introduced. Bovine serum Immunoglobulin G (IgG) and bovine serum albumin (BSA) were used as the model proteins. The adsorption isotherms of IgG and BSA were investigated at different pH values ranging from 4.0–8.9 to evaluate the adsorption performance, and protein-ligand molecular interactions were explored through addition of sodium chloride and glycerol. The results showed that both of adsorbents coupled with AMP or AMA had lower saturated binding capacities ( Q m ) towards BSA and higher adsorption capacity ratio of IgG to BSA when compared to BA-based adsorbents. The contributions of electrostatic interactions and hydrophobic interactions to proteins binding were different among these phenyl-based mixed mode adsorbents. Finally, AMP-based adsorbent possessing high adsorption capacity ratio of IgG to BSA and salt tolerance was selected to separate IgG from mimetic serum with purity higher than 96 %. The results indicated adjusting the functional groups of ligand to regulate the electrostatic and hydrophobic interactions of protein-ligand was useful to improve the antibody separation performance of mixed-mode adsorbents.
研究领域:
生物分离工程
·
免疫学
·
生物材料
·
蛋白质工程
·
生物制药
·
分子识别
·
层析技术
✓ 已验证
DOI
高影响因子
JOURNAL OF SOLID STATE CHEMISTRY
·
2022
·
IF 3.656
Liang Qin,Yan Li,Deyun Ma,Fenglan Liang,Lidian Chen,Chenyang Xie,Jiayong Lin,Yani Pan,Guizhen Li,Fenrou Chen,Peiru Xu,Canlin Hong,Jiaxing Zhu
Two transition metal-based MOFs , {[Ni 2 (pip) 2 (bimb) 1.5 ]·2(H 2 O)} n ( 1 ), and {[Zn(pip)(bimb)]·DMF} n ( 2 ) (pip = 5-phenyl-isophthalate, bimb = 1,4-bis(imidazole-1-ylmethyl)benzene) have been successfully prepared. Complex 1 displays a three-dimensional structure with a 7-connected svk topology with a point symbol of (3 3 ∙4 14 ∙5 3 ∙6). Complex 2 performs a two-dimensional (4,4) sql net with channels of 7.0 × 5.5 Å 2 and 10.5 × 4.7 Å 2 along the b and c axis, respectively. The magnetic result of 1 shows an antiferromagnetic coupling between the two metal centers. Desolvated 2 adsorbs around 15.25 wt% 5-fluorouracil (5-FU). The 5-FU was slowly released without any burst release. The degradation of methyl orange caused by oxidizing sulfate radicals (SO 4− ) in a Fenton-like process has also been explored.
研究领域:
无机化学
·
材料科学
·
药物递送
·
环境催化
·
配位化学
✓ 已验证
DOI
高影响因子
RSC Advances
·
2016
·Vol. 6
·期 27
·22908-22916
·
IF 3.289
Jianwen Tian,Xiaohui He,Jingyin Liu,Xiaodan Deng,Defu Chen
Palladium(II) and copper(II) chloride complexes bearing bulky 9,10-dihydro-9,10-ethanoanthracene-11,12-diimine ligands were synthesized and sufficiently characterized by elemental and spectroscopic analysis along with X-ray diffraction analysis. The X-ray diffraction demonstrated that palladium(II) complexes (C1–C2) and copper(II) complexes (C3–C4) were four-coordinated. All these complexes displayed catalytic activities up to 105 gpolymer molMt−1 h−1 for norbornene vinyl-addition polymerization on treatment with excess methylaluminoxane (MAO). The parameters of the reaction conditions, the type of metals and steric effects of coordinative ligands had influences on the catalytic properties. C2 was selected as a catalyst precursor for the copolymerization of norbornene (NB) with 2-butyloxymethylene norbornene (BN), which exhibited catalytic activities up to 1.1 × 105 gpolymer molPd−1 h−1 and produced copolymers with relatively high molecular weights. The fraction of BN in the copolymer could reach up to 9.8–62.1% by controlling the monomer feed ratio range from 10–80%. The achieved vinyl-addition type poly(NB-co-BN) displayed high thermal stability and was soluble in common organic solvents, such as CHCl3 and THF.
研究领域:
高分子化学
·
配位化学
·
催化化学
·
有机金属化学
·
功能高分子材料
✓ 已验证
DOI
高影响因子
JOURNAL OF COLLOID AND INTERFACE SCIENCE
·
2015
·
IF 3.368
Xiang Shen,Bing Yan
A series of luminescent Ln 3+ @bio-MOF-1 (Ln = Eu, Tb, bio-MOF-1 = Zn 8 (ad) 4 (BPDC) 6 O⋅2Me 2 NH 2 (ad = adeninate, BPDC = biphenyldicarboxylate)) are synthesized via postsynthetic cation exchange by encapsulating lanthanide ions into an anionic metal–organic framework (MOF), and their photophysical properties are studied. After loading 2-thenoyltrifluroacetone (TTA) as sensitized ligand by a gas diffusion (“ship-in-bottle”) method, it is found that the luminescent intensity of Eu 3+ is enhanced. Especially, when loading two different lanthanide cations into bio-MOF-1, the luminescent color can be tuned to close white (light pink) light output. Additionally, bio-MOF-1 and Eu 3+ @bio-MOF-1 are selected as representative samples for sensing metal ions . When bio-MOF-1 is immersed in the aqueous solutions of different metal ions , it shows highly sensitive sensing for Fe 3+ as well as Eu 3+ @bio-MOF-1 immersed in the DMF solutions of different metal ion. The results are benefit for the further application of functionalized bio-MOFs in practical fields.
研究领域:
无机化学
·
材料科学
·
分析化学
·
纳米生物技术
·
光物理学
·
配位化学
✓ 已验证
DOI
高影响因子
危险品化学品经营许可证（带存储）