Herein, a novel bright-green and highly fluorescent polyethyleneimine capped copper nanoclusters (CuNCs@PEI) has been hydrothermally synthesized, which is employed as a fluorescence probe to determine rifampicin. Under optimum synthetic conditions, the morphology, surface chemistry and optical features of resulting CuNCs@PEI are well characterized by transmission electron microscopy, Fourier transform infrared spectroscopy, UV–Vis absorption spectra, transient and steady-state fluorescence. In comparison to previous reports, the new species with a larger diameter of approximately 3 nm exhibit higher fluorescence quantum yield (QY) up to nearly 10.7%, and demonstrate tolerability to extreme pH, high ionic strengths as well as long-term UV irradiation. These excellent optical properties ascribe to unique grain size and surface chemical features of products, which are further discussed in this work. In addition, we employed as-prepared CuNCs@PEI to detect rifampicin based on fluorescence quenching phenomenon. The fluorescence intensity of probe is linearly proportional to rifampicin over the concentration rage from 0 to 20 μM, where the limit of detection (LOD) is 50 nM. Besides, this probe can be also used to assay rifampicin in serum samples with satisfactory recoveries.
Zhenguang Wang,Yu-e Shi,Xuming Yang,Yuan Xiong,Yanxiu Li,Bingkun Chen,Wing-Fu Lai,Andrey L. Rogach
A water-soluble, positively charged polymer is obtained by copolymerizing chitosan with hypromellose, and the evaluation of its biocompatibility and the capacity for the loading of exogenous agents is performed. Films based on hypromellose grafted chitosan (HGC) are employed as a matrix to fabricate composite films by dehydration-triggered aggregation of copper nanoclusters (NCs). The resulting HGC/Cu NC films are transparent and exhibit an aggregation-induced emission enhancement of copper NCs, with a resulting photoluminescence quantum yield of 42%. The application of these orange emitting films as color converters for fabrication of remote light-emitting devices is demonstrated.
危险品化学品经营许可证（带存储）