Mtb-cyt-bd oxidase-IN-6 is a potent Mycobacterium tuberculosis ( Mtb ) cytochrome bd (cyt-bd) oxidase ( MtbCyt-bd Oxidase ) inhibitor with an IC 50 value of 0.35 μM. Mtb-cyt-bd oxidase-IN-6 can effectively inhibit the growth of Mtb (MIC= 4 μM). Mtb-cyt-bd oxidase-IN-6 can be used in the study of tuberculosis.