MG-T-19 is an effective TIM-3 inhibitor that can suppress the interaction of TIM-3 with PtdSer , CEACAM1 , and Gal-9. MG-T-19 can increase the production of tumor necrosis factor-α ( TNF-α ) and interferon-γ ( IFN-γ ) in peripheral blood mononuclear cells (PBMCs) from healthy donors, and enhance the ability of PBMCs to inhibit the proliferation of Kasumi-1 cells (an acute myelogenous leukemia cell line).