Menin-MLL inhibitor 29 (Compound C1) is a Menin-MLL PPI inhibitor. Menin-MLL inhibitor 29 binds to Menin with a K D value of 138 nM, and inhibits the binding of Menin to MBM1 (Menin-binding motif 1) with an IC 50 value of 46 nM. Menin-MLL inhibitor 29 inhibits HepG2 and Hep3B hepatoma cell proliferation (IC 50 s: 0.31 μM and 0.71 μM). Menin-MLL inhibitor 29 inhibits tumor growth.