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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
MAO(EC1.4.3.4) 主要存在于脊椎动物的各种器官，特别是分泌腺、脑、肝脏，在无脊椎动物、豆类的芽等植物中也存在催化单胺类物质代谢，含量较低，具有重要的生理功能，其活性能反映肝纤维化的程度。此外，MAO活性异常导致细胞内单胺类神经递质运转出现紊乱，从而引发多种病症。 测定原理：MAO催化单胺类底物脱氨生成相应的醛，进一步氧化成酸，底物在360nm处有特征吸收峰，测定360nm光吸收下降的速率，计算MAO活性。
Monoamine Oxidase (MAO) (EC 1.4.3.4) is primarily found in various organs of vertebrates, especially in secretory glands, the brain, and the liver. It also exists at lower levels in invertebrates and plants such as bean sprouts, where it catalyzes the metabolism of monoamine substances and plays important physiological roles. Its activity can reflect the degree of liver fibrosis. Moreover, abnormal MAO activity leads to disruptions in the transport of intracellular monoamine neurotransmitters, thereby contributing to the development of various diseases. Assay Principle: MAO catalyzes the deamination of monoamine substrates to produce corresponding aldehydes, which are further oxidized into acids. The substrate exhibits a characteristic absorption peak at 360 nm, and the activity of MAO is calculated by measuring the rate of decrease in absorbance at 360 nm.
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