阿拉丁提供二氧化锰（MnO₂）纳米片，尺寸约为100 nm，具有类过氧化氢酶（CAT） 活性和类超氧化物歧化酶（SOD）活性，可用做抗氧化剂，清除自由基。同时MnO₂纳米片作为氧气（O₂） 产生器可以催化过氧化氢（H₂O₂）产生大量O₂，环境组织缺氧；还可作为磁共振成像造影剂使用被广泛应用于肿瘤治疗、细菌感染治疗以及生物传感检测等生物医学领域。
| 货号 | M1520772
|
| 产品名称 | 二氧化锰纳米片
|
浓度
| 1 mg/mL
|
平均粒径
| 100 nm
|
Zeta 电位
| 约-40 mV
|
保存溶液
| 纯化水 |
表征数据
1. TEM 表征
图1. MnO₂ 的 TEM 图像：纳米片尺寸比较均匀，约为 100 nm
2. 水动力尺寸和 Zeta 电位表征
图2. MnO₂纳米片的DLS图（左边：Intensity，右边：Number）
MnO₂的DLS Intensity值为159.2 nm，Number 值为97.2 nm
3. Zeta 电位表征
图3. MnO₂ 纳米片的Zeta图
MnO₂的Zeta值为-44.45 mV
酶活性测试
1. 类过氧化氢酶（CAT）活性
如图4所示：将 MnO₂ 纳米片与 H₂O₂ 在纯水中混合后生成大量气泡，说明 MnO₂ 利用其类 CAT 活性催化 H₂O₂ 产生了大量氧气。
图4. MnO₂纳米片催化H₂O₂产生大量O₂泡
2. 类氧化酶（OXD）活性
如图5所示：MnO₂ 纳米片与 TMB 溶液混合后形成蓝色物质，说明 MnO₂ 利用其 OXD 活性氧化 TMB 形成氧化 TMB（oxTMB），oxTMB 与 TMB 结合形成蓝色物质。
图5. MnO₂纳米片氧化TMB，溶液变蓝色（左为 MnO₂ 纳米片与 TMB 混合液，右为 TMB 水溶液）
注意事项
超声分散后使用。
Aladdin provides Manganese Dioxide (MnO₂) Nanosheets with a size of approximately 100 nm. They exhibit catalase (CAT)-like activity and superoxide dismutase (SOD)-like activity, and can be used as antioxidants to scavenge free radicals. Meanwhile, MnO₂ nanosheets act as oxygen (O₂) generators, catalyzing hydrogen peroxide (H₂O₂) to produce a large amount of O₂, thereby alleviating tissue hypoxia. They can also serve as magnetic resonance imaging (MRI) contrast agents and are widely used in biomedical fields such as tumor therapy, bacterial infection therapy, and biosensing.
Cat. No.
| M1520772
|
Product Name
| Molybdenum Disulfide Nanoparticles
|
Concentration
| 1 mg/mL
|
Average Size
| 100 nm
|
Zeta Potential
| Approx. -40 mV
|
Storage Solution
| Purified water
|
Characterization Data
1. TEM Characterization
Figure 1. TEM image of MnO₂ nanosheets showing relatively uniform size of approximately 100 nm.
2. Hydrodynamic Size and Zeta Potential Characterization
Figure 2. DLS plot of MnO₂ nanosheets (Left: Intensity; Right: Number)
The DLS Intensity value of MnO₂ is 159.2 nm, and the Number value is 97.2 nm.
3. Zeta Potential Characterization
Figure 3. Zeta plot of MnO₂ nanosheets
The Zeta potential value of MnO₂ is -44.45 mV.
Enzyme Activity Tests
1. Catalase (CAT)-Like Activity
As shown in Figure 4: When MnO₂ nanosheets are mixed with H₂O₂ in purified water, a large number of bubbles are generated, indicating that MnO₂ utilizes its CAT-like activity to catalyze H₂O₂ and produce a large amount of oxygen.
Figure 4. MnO₂ nanosheets catalyze H₂O₂ to generate abundant O₂ bubbles.
2. Oxidase (OXD)-Like Activity
As shown in Figure 5: When MnO₂ nanosheets are mixed with TMB solution, a blue color develops, indicating that MnO₂ utilizes its OXD-like activity to oxidize TMB to oxTMB, which then combines with TMB to form a blue substance.
Figure 5. Oxidation of TMB by MnO₂ nanosheets, turning the solution blue (Left: mixture of MnO₂ nanosheets and TMB; Right: TMB aqueous solution).
Note
ZJ26F0434419
危险品化学品经营许可证（带存储）